WO2000008209A3 - Nucleic acids encoding human tbc-1 protein and polymorphic markers thereof - Google Patents

Nucleic acids encoding human tbc-1 protein and polymorphic markers thereof Download PDF

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Publication number
WO2000008209A3
WO2000008209A3 PCT/IB1999/001444 IB9901444W WO0008209A3 WO 2000008209 A3 WO2000008209 A3 WO 2000008209A3 IB 9901444 W IB9901444 W IB 9901444W WO 0008209 A3 WO0008209 A3 WO 0008209A3
Authority
WO
WIPO (PCT)
Prior art keywords
tbc
protein
nucleic acids
acids encoding
encoding human
Prior art date
Application number
PCT/IB1999/001444
Other languages
French (fr)
Other versions
WO2000008209A2 (en
Inventor
Marta Blumenfeld
Lydie Bougueleret
Ilya Chumakov
Original Assignee
Genset Sa
Marta Blumenfeld
Lydie Bougueleret
Ilya Chumakov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US09/762,311 priority Critical patent/US6825004B1/en
Application filed by Genset Sa, Marta Blumenfeld, Lydie Bougueleret, Ilya Chumakov filed Critical Genset Sa
Priority to CA002337694A priority patent/CA2337694A1/en
Priority to EP99936910A priority patent/EP1108059A2/en
Priority to AU51878/99A priority patent/AU774440B2/en
Priority to JP2000563831A priority patent/JP2002532057A/en
Publication of WO2000008209A2 publication Critical patent/WO2000008209A2/en
Publication of WO2000008209A3 publication Critical patent/WO2000008209A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention concerns genomic and cDNA sequences of the human TBC-1 Gene. The invention also concerns polypeptides encoded by the TBC-1 gene. The invention also deals with antibodies directed specifically against such polypeptides that are useful as diagnostic reagents. The invention further encompasses biallelic markers of the TBC-1 gene useful in genetic analysis.
PCT/IB1999/001444 1998-08-07 1999-08-06 Nucleic acids encoding human tbc-1 protein and polymorphic markers thereof WO2000008209A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US09/762,311 US6825004B1 (en) 1998-08-07 1999-06-08 Nucleic acids encoding human TBC-1 protein and polymorphic markers thereof
CA002337694A CA2337694A1 (en) 1998-08-07 1999-08-06 Nucleic acids encoding human tbc-1 protein and polymorphic markers thereof
EP99936910A EP1108059A2 (en) 1998-08-07 1999-08-06 Nucleic acids encoding human tbc-1 protein and polymorphic markers thereof
AU51878/99A AU774440B2 (en) 1998-08-07 1999-08-06 Nucleic acids encoding human TBC-1 protein and polymorphic markers thereof
JP2000563831A JP2002532057A (en) 1998-08-07 1999-08-06 Nucleic acid encoding human TBC-1 protein and polymorphic marker thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9565398P 1998-08-07 1998-08-07
US60/095,653 1998-08-07

Publications (2)

Publication Number Publication Date
WO2000008209A2 WO2000008209A2 (en) 2000-02-17
WO2000008209A3 true WO2000008209A3 (en) 2000-11-09

Family

ID=22252989

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1999/001444 WO2000008209A2 (en) 1998-08-07 1999-08-06 Nucleic acids encoding human tbc-1 protein and polymorphic markers thereof

Country Status (5)

Country Link
EP (1) EP1108059A2 (en)
JP (1) JP2002532057A (en)
AU (1) AU774440B2 (en)
CA (1) CA2337694A1 (en)
WO (1) WO2000008209A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700927A (en) * 1994-12-23 1997-12-23 The Children's Medical Center Corporation Tbc1 gene and uses thereof
WO1998020165A2 (en) * 1996-11-06 1998-05-14 Whitehead Institute For Biomedical Research Biallelic markers
WO1999032644A2 (en) * 1997-12-22 1999-07-01 Genset Prostate cancer gene

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700927A (en) * 1994-12-23 1997-12-23 The Children's Medical Center Corporation Tbc1 gene and uses thereof
WO1998020165A2 (en) * 1996-11-06 1998-05-14 Whitehead Institute For Biomedical Research Biallelic markers
WO1999032644A2 (en) * 1997-12-22 1999-07-01 Genset Prostate cancer gene

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BERTHON P ET AL: "PREDISPOSING GENE FOR EARLY-ONSET PROSTATE CANCER, LOCALIZED ON CHROMOSOME 1Q42.2-43", AMERICAN JOURNAL OF HUMAN GENETICS,US,UNIVERSITY OF CHICAGO PRESS, CHICAGO,, vol. 62, no. 6, June 1998 (1998-06-01), pages 1416 - 1424, XP000857378, ISSN: 0002-9297 *
FAN J ET AL: "Genetic mapping: Finding and analyzing single-nucleotide polymorphisms with high-density DNA arrays", AMERICAN JOURNAL OF HUMAN GENETICS,US,UNIVERSITY OF CHICAGO PRESS, CHICAGO,, vol. 61, no. 4, SUPPL, 1 October 1997 (1997-10-01), pages 1601, XP002089397, ISSN: 0002-9297 *
WANG D G ET AL: "Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome", SCIENCE,US,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, vol. 280, 1998, pages 1077 - 1082, XP002089398, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
WO2000008209A2 (en) 2000-02-17
EP1108059A2 (en) 2001-06-20
CA2337694A1 (en) 2000-02-17
JP2002532057A (en) 2002-10-02
AU5187899A (en) 2000-02-28
AU774440B2 (en) 2004-06-24

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