WO2000004887A3 - Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders - Google Patents

Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders Download PDF

Info

Publication number
WO2000004887A3
WO2000004887A3 PCT/CA1999/000655 CA9900655W WO0004887A3 WO 2000004887 A3 WO2000004887 A3 WO 2000004887A3 CA 9900655 W CA9900655 W CA 9900655W WO 0004887 A3 WO0004887 A3 WO 0004887A3
Authority
WO
WIPO (PCT)
Prior art keywords
omega
mixtures
derivatives
composition
fatty acids
Prior art date
Application number
PCT/CA1999/000655
Other languages
French (fr)
Other versions
WO2000004887A2 (en
Inventor
Egon Novak
Original Assignee
Forbes Medi Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forbes Medi Tech Inc filed Critical Forbes Medi Tech Inc
Priority to AU48916/99A priority Critical patent/AU4891699A/en
Priority to EP99932570A priority patent/EP1102591A2/en
Priority to CA002346881A priority patent/CA2346881A1/en
Publication of WO2000004887A2 publication Critical patent/WO2000004887A2/en
Publication of WO2000004887A3 publication Critical patent/WO2000004887A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11Plant sterols or derivatives thereof, e.g. phytosterols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A composition for use in preventing and treating cardiovascular disease and other disorders comprises one or more phytosterols, phytostanols or mixtures of both, and one or more omega-3 polyunsaturated fatty acids or derivatives thereof.
PCT/CA1999/000655 1998-07-20 1999-07-20 Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders WO2000004887A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU48916/99A AU4891699A (en) 1998-07-20 1999-07-20 Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders
EP99932570A EP1102591A2 (en) 1998-07-20 1999-07-20 Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders
CA002346881A CA2346881A1 (en) 1998-07-20 1999-07-20 Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11880998A 1998-07-20 1998-07-20
US09/118,809 1998-07-20

Publications (2)

Publication Number Publication Date
WO2000004887A2 WO2000004887A2 (en) 2000-02-03
WO2000004887A3 true WO2000004887A3 (en) 2000-05-04

Family

ID=22380876

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA1999/000655 WO2000004887A2 (en) 1998-07-20 1999-07-20 Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders

Country Status (4)

Country Link
EP (1) EP1102591A2 (en)
AU (1) AU4891699A (en)
CA (1) CA2346881A1 (en)
WO (1) WO2000004887A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID24148A (en) * 1998-11-26 2000-07-13 Hoffmann La Roche FITOSTFROL AND / OR FITOSTANOL DRIVINGS
US6998501B1 (en) 1999-08-30 2006-02-14 Ocean Nutrition Canada Limited Nutritional supplement for lowering serum triglyceride and cholesterol levels
NO313076B1 (en) 1999-12-28 2002-08-12 Pronova Biocare As Liquid nutrients and / or nutrients and processes for their preparation
AU2001242130A1 (en) * 2000-03-07 2001-09-17 Forbes Medi-Tech Inc. Novel derivatives comprising phytosterols and/or phytostanols and alpha-lipoic and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders
US7144595B2 (en) 2001-11-16 2006-12-05 Brandeis University Prepared foods containing triglyceride-recrystallized non-esterified phytosterols
US7514107B2 (en) 2002-03-21 2009-04-07 Mars, Incorporated Treatment of diseases involving defective gap junctional communication
WO2004029068A1 (en) * 2002-09-25 2004-04-08 Forbes Medi-Tech Inc. Derivatives comprising sterols and/or stanols and specific classes of anti-inflammatory agents and use thereof in treating or preventing cardiovascular disease
US7575768B2 (en) 2005-09-07 2009-08-18 Brandeis University Dietary supplements and prepared foods containing triglyceride-recrystallized non-esterified phytosterols
FI20051184A0 (en) * 2005-11-18 2005-11-18 Raisio Yhtymae Oyj Improved fat composition
CA2673005A1 (en) * 2005-12-20 2007-06-28 Forbes Medi-Tech Inc. Emulsions comprising non-esterified phytosterols in the aqueous phase
US20070254026A1 (en) * 2006-05-01 2007-11-01 Forbes Medi-Tech Inc. Softgel capsules
EP2020874A4 (en) * 2006-05-01 2015-07-15 Pharmachem Lab Inc Composition comprising one or more esterified phytosterols and/or phytostanols into which are solubilized one or more unesterified phytosterols and/or phytostanols, in order to achieve therapeutic and formulation benefits
US20080199589A1 (en) * 2007-02-20 2008-08-21 Cargill, Incorporated Lipid Microemulsions
FR2943506B1 (en) * 2009-03-25 2014-08-29 Lesieur Sas FOOD COMPOSITION ALLEGED IN FAT, POOR IN SALT, RICH IN OMEGA-3 AND ENRICHED IN PHYTOSTEROLS
US20110038848A1 (en) 2009-08-12 2011-02-17 Melaleuca, Inc. Dietary supplement compositions for cardiovascular health
US9119826B2 (en) * 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
CN113967192A (en) * 2021-11-09 2022-01-25 陕西海斯夫生物工程有限公司 Pharmaceutical composition for accelerating wound healing, preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581310A1 (en) * 1985-05-02 1986-11-07 Natura Medica Laboratoires THERAPEUTIC COMPOSITION COMPRISING A-LINOLENIC ACID AND A COMPOUND CAPABLE OF PROMOTING ACID PASSAGE THROUGH CELL MEMBRANE AND PLANT EXTRACT COMPRISING ACID AND COMPOUND
WO1998001759A1 (en) * 1996-07-03 1998-01-15 Forbes Medi-Tech Inc. A method of assessing risk for cardiovascular disease and other disorders and phytosterol-based compositions useful in preventing and treating cardiovascular disease and other disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1707572T3 (en) 1994-09-29 2014-05-12 Univ British Columbia Sterol compositions from pulp soap

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581310A1 (en) * 1985-05-02 1986-11-07 Natura Medica Laboratoires THERAPEUTIC COMPOSITION COMPRISING A-LINOLENIC ACID AND A COMPOUND CAPABLE OF PROMOTING ACID PASSAGE THROUGH CELL MEMBRANE AND PLANT EXTRACT COMPRISING ACID AND COMPOUND
WO1998001759A1 (en) * 1996-07-03 1998-01-15 Forbes Medi-Tech Inc. A method of assessing risk for cardiovascular disease and other disorders and phytosterol-based compositions useful in preventing and treating cardiovascular disease and other disorders

Also Published As

Publication number Publication date
WO2000004887A2 (en) 2000-02-03
AU4891699A (en) 2000-02-14
CA2346881A1 (en) 2000-02-03
EP1102591A2 (en) 2001-05-30

Similar Documents

Publication Publication Date Title
WO2000004887A3 (en) Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders
DK1075191T3 (en) Phytosterolcompositions
WO2000015201A3 (en) Compositions comprising one or more phytosterols, phytostanols or mixtures of both and one or more alpha, beta, delta, or gamma tocotrienols or derivatives thereof and use of the compositions in treating or preventing cardiovascular disease, its underlying conditions and other disorders
EP1143956A3 (en) Compositions and methods for the treatment of anorectal disorders
IL135800A0 (en) Methods and pharmaceutical compositions for the closure of retinal breaks
PL331515A1 (en) Stannoles containing composition and application thereof
HUP0303354A3 (en) 6-alpha, 9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-betha-hydroxy-16-alpha-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect, process for its preparation and pahrmaceutical composition containing it
CA2325360A1 (en) Compositions comprising osteoprotegerin for the prevention and treatment of cardiovascular diseases
AP2000002010A0 (en) Novel pharmaceutical compositions for treating and saving and the methods for the preparation thereof
HUP0002171A3 (en) Aminophosphonic acid derivatives, method for their preparation and pharmaceutical compositions thereof
EP1335736A4 (en) Compositions and methods for diagnosis and treatment of cardiovascular disorders
AU2001242130A1 (en) Novel derivatives comprising phytosterols and/or phytostanols and alpha-lipoic and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders
WO2003039490A9 (en) Compositions and methods for diagnosing and treating mental disorders
AU4834200A (en) Fatty acid-n-substituted indol-3-glyoxyl-amide compositions and uses thereof
HUP0203429A3 (en) Immunomodulatory steroids, in particular the hemihydrate of 16.alpha.-bromoepiandrosterone, process for their preparation and pharmaceutical compositions containing them
IL116828A0 (en) Use of 3,4-diphenyl chromans for the preparation of pharmaceutical compositions
IL116745A0 (en) Use of 3,4-diphenyl chromans for the preparation of pharmaceutical compositions
AU2001247471A1 (en) Compositions and methods of treating, reducing, and preventing cardiovascular diseases and disorders with polymethoxyflavones
EP0764438A3 (en) Composition for permanent waving of human hair
AU2001264522A1 (en) Methods and compositions for the prevention of myopia
IL139863A0 (en) 3,4-diphenyl bicyclo [4.3.0] nonyl derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same
ZA972708B (en) Pharmaceutical compositions and methods for the manufacture thereof.
AUPQ872800A0 (en) Compositions and methods for treating cardiovascular disorders
AUPP687298A0 (en) Herbal compositions for treatment of gastrointestinal disorders
EP1315499A4 (en) Compositions and methods for the treatment of anorectal disorders

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 1999932570

Country of ref document: EP

Ref document number: 48916/99

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2346881

Country of ref document: CA

Kind code of ref document: A

Ref document number: 2346881

Country of ref document: CA

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 1999932570

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: CA