WO2000003681A3 - Procede de synthese de derives de benzopyrane - Google Patents

Procede de synthese de derives de benzopyrane Download PDF

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Publication number
WO2000003681A3
WO2000003681A3 PCT/US1999/015993 US9915993W WO0003681A3 WO 2000003681 A3 WO2000003681 A3 WO 2000003681A3 US 9915993 W US9915993 W US 9915993W WO 0003681 A3 WO0003681 A3 WO 0003681A3
Authority
WO
WIPO (PCT)
Prior art keywords
synthesis
benzopyran derivatives
formula
benzopyran
compounds represented
Prior art date
Application number
PCT/US1999/015993
Other languages
English (en)
Other versions
WO2000003681A2 (fr
Inventor
James Guy Breitenbucher
Hon C Hui
Gianine M Figliozzi
Original Assignee
Axys Pharm Inc
James Guy Breitenbucher
Hon C Hui
Gianine M Figliozzi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axys Pharm Inc, James Guy Breitenbucher, Hon C Hui, Gianine M Figliozzi filed Critical Axys Pharm Inc
Priority to AU49971/99A priority Critical patent/AU4997199A/en
Publication of WO2000003681A2 publication Critical patent/WO2000003681A2/fr
Publication of WO2000003681A3 publication Critical patent/WO2000003681A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Abstract

La présente invention se rapporte à un procédé de synthèse de composés à base de benzopyrane représentés par la formule (1). Elle se rapporte également à de nouveaux composés à base de benzopyrane représentés par la formule (E) et la formule (3).
PCT/US1999/015993 1998-07-16 1999-07-14 Procede de synthese de derives de benzopyrane WO2000003681A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU49971/99A AU4997199A (en) 1998-07-16 1999-07-14 Process for the synthesis of benzopyran derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9314298P 1998-07-16 1998-07-16
US60/093,142 1998-07-16

Publications (2)

Publication Number Publication Date
WO2000003681A2 WO2000003681A2 (fr) 2000-01-27
WO2000003681A3 true WO2000003681A3 (fr) 2000-04-20

Family

ID=22237427

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/015993 WO2000003681A2 (fr) 1998-07-16 1999-07-14 Procede de synthese de derives de benzopyrane

Country Status (2)

Country Link
AU (1) AU4997199A (fr)
WO (1) WO2000003681A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001010798A1 (fr) * 1999-08-04 2001-02-15 Chemrx Advanced Technologies, Inc. Synthese en phase solide d'oxa- et de thiazoles
EP1931681B1 (fr) * 2005-10-07 2012-11-14 Glenmark Pharmaceuticals S.A. Dérivés benzofusionnés substitués et leur utilisation en tant que ligands des récepteurs vanilloïdes
WO2007063385A2 (fr) * 2005-12-01 2007-06-07 Pfizer Products Inc. Antagonistes des recepteurs de l'histamine 3 pour des amines spirocycliques
MX2010005704A (es) * 2007-12-18 2010-08-17 Glenmark Pharmaceuticals Sa Derivados de cromano como modulares del trpv3.
WO2018231745A1 (fr) 2017-06-14 2018-12-20 Trevena, Inc. Composés pour moduler l'activité de s1p1 et leurs procédés d'utilisation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401848A (en) * 1990-11-26 1995-03-28 E. R. Squibb & Sons, Inc. Indane and quinoline derivatives
US5453421A (en) * 1992-09-11 1995-09-26 E. R. Squibb & Sons, Inc. Aryl and heterocyclic substituted propenamide derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5889044A (en) * 1991-06-13 1999-03-30 Smithkline Beecham P.L.C. Benzo- and pyridopyran derivatives having anxiolytic and anti-convulsant activity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401848A (en) * 1990-11-26 1995-03-28 E. R. Squibb & Sons, Inc. Indane and quinoline derivatives
US5889044A (en) * 1991-06-13 1999-03-30 Smithkline Beecham P.L.C. Benzo- and pyridopyran derivatives having anxiolytic and anti-convulsant activity
US5453421A (en) * 1992-09-11 1995-09-26 E. R. Squibb & Sons, Inc. Aryl and heterocyclic substituted propenamide derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives

Also Published As

Publication number Publication date
WO2000003681A2 (fr) 2000-01-27
AU4997199A (en) 2000-02-07

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