WO2000002606A1 - A medication delivery device and a cartridge assembly for use in the same - Google Patents
A medication delivery device and a cartridge assembly for use in the same Download PDFInfo
- Publication number
- WO2000002606A1 WO2000002606A1 PCT/DK1999/000387 DK9900387W WO0002606A1 WO 2000002606 A1 WO2000002606 A1 WO 2000002606A1 DK 9900387 W DK9900387 W DK 9900387W WO 0002606 A1 WO0002606 A1 WO 0002606A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- assembly
- cartridge
- dosing
- delivery device
- cartridge assembly
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2492—Ampoule holder connected to rest of syringe via snap connection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
Definitions
- the present invention relates to a medication delivery device having a cartridge assembly and a dosing assembly coupled together for delivering selected doses of medication.
- Some medication such as insulin is self-administered.
- the typical diabetes patient will require injections of insulin several times during the day.
- the required insulin dose will vary from patient to patient, and will for each patient often also vary during the day.
- Each patient will often establish a regimen for the insulin administration adjusted to his or her insulin need as well as lifestyle.
- Medication delivery pens have been developed to facilitate the self-administration of medication, such as insulin.
- One prior art medication delivery pen includes a pen body assembly comprising a medication cartridge and a plunger device.
- a needle assembly may be connected to the pen body assembly.
- the medication is delivered by moving or pressing a plunger in the direction of the needle assembly thereby delivering the medication.
- the pen body assembly is dis- carded.
- the needle assembly will often have to be displaced by a new assembly or new needle due to increasing bluntness of the needle making injections painful for the patient.
- medication delivery pens were developed, for which pens only a part of the pen was discarded after medication exhaustion, such as the cartridge only.
- a medication de- livery pen has a reusable pen body assembly and a disposable cartridge assembly that are threadedly engageable with one another.
- the disposable cartridge assembly includes a plunger and can releasably receive a needle cannula assembly through a threaded coupling.
- a driving means in the pen body assembly engages the plunger after engagement of the pen body assembly and the cartridge assembly, whereby the pen is ready for dosing the medicine within the cartridge.
- the cartridge holder assembly can be disassembled from the pen body assembly after the medication therein has been exhausted, discarded and replaced.
- a drawback of the above-mentioned pen is that the driving means of the pen body may be disengaged from the plunger of the cartridge during normal use resulting in inaccurate dosing of the medicine.
- the needle assembly will often have to be replaced independently of replacement of the cartridge.
- the cartridge assembly may inadvertently be released or partly released from the pen body assembly.
- the driving means of the pen body may be disengaged from the plunger of the cartridge.
- the user will most probably not be aware of the disengagement but will receive only a portion or even nothing of the medicine.
- a medication delivery device which comprises
- a cartridge assembly having one end sealed with a pierceable sealing, said end of the cartridge assembly comprising coupling means for releasably mounting a needle assembly, and comprising a cartridge having a stopper adapted to receive plunger means,
- a dosing assembly comprising plunger means
- the device further comprises means for securing that the plunger means abuts on the stopper during use of the device
- a second aspect of the present invention is a medication delivery device wherein the dosing assembly is releasably coupled to the cartridge assembly
- the plunger means must disengage the stopper when the cartridge assembly is deliberately released from the dosing assembly because the medication in the cartridge has been exhausted and the cartridge assembly is to be discarded In this situation the plunger means is to be retracted to the dosing assembly before assembling the device with a new cartridge assembly
- Securing the abutment of the plunger means on the stopper during use of the medication delivery device, in particular when the needle assembly is coupled to and/or decoupled from the cartridge assembly, may be carried out by a variety of means
- the abutment is secured by preventing the cartridge as- sembly from being inadvertently released from the dosing assembly
- the dosing assembly is coupled to the cartridge assembly at the end of the cartridge assembly opposite the means for mounting the needle assembly, and the plunger means is a rod element adapted to exert an axial movement of the stopper towards the sealed end of the cartridge.
- the means for coupling the dosing assembly and the cartridge assembly together are such that the coupling and/or decoupling of the needle assembly does not cause an axial movement of the cartridge assembly with respect to the dosing assembly.
- the rod element does not disengage the stopper in the cartridge when the user attaches the needle assembly or removes it after use. Thereby the user can be confident of the accuracy of the dosage selected.
- the means for coupling the dosing assembly and the cartridge assembly together may be any suitable coupling, preferably a releasable coupling.
- suitable coupling preferably a releasable coupling.
- the coupling are snap locks, such as snap locks with guidewire and sideways snap locks, snap locks released through threads, bajonet locks, luer locks, hinged locks, threaded locks and any suitable combinations thereof.
- the means for releasably coupling the needle assembly and the cartridge assembly together are such that the coupling and/or decoupling of the needle assembly cannot cause an axial movement of the cartridge assembly with respect to the dosing assembly.
- the preferred couplings between the needle assembly and the cartridge assembly include releasable snap locks.
- Another preferred embodiment includes a safety on the coupling between the dosing assembly and the cartridge assembly, such as hinge on the coupling or a threaded coupling releasable only after exerting an axial pressure on the coupling.
- preferred combinations of couplings between the dosing assembly and the cartridge assembly and between the needle assembly and the cartridge assembly, respectively, are a threaded coupling combined with a snap coupling, a bajonet lock or a luer lock combined with a snap lock, or a snap lock combined with a snap lock, or any other combination for which the couplings are independently working.
- the cartridge assembly comprises a cartridge for the medication to be delivered.
- the cartridge assembly has one end sealed with a pierceable sealing, said end of the cartridge assembly comprising coupling means for releasable mounting a needle assembly, and another end com- prising coupling means adapted to engage a dosing assembly.
- the cartridge comprises a stopper.
- the cartridge assembly may further comprise a housing for protecting at least a part of the cartridge assembly.
- At least one of the coupling means of the cartridge assembly is unitarily moulded with the cartridge, and in a more preferred embodiment all the coupling means are unitarily moulded with the cartridge.
- the cart ⁇ dge assembly may be comprised of just one part, i.e. the cartridge including the coupling means.
- the invention in another embodiment relates to a medication delivery device for transferring medication from the cartridge into a syringe with a needle.
- the coupling means for engaging the needle assembly may be replaced by coupling means for engaging the syringe, or coupling means for both may be provided.
- the coupling means may be a syringe holder, for example a cylinder coupled to the cartridge comprising a central bore for receiving the syringe.
- the syringe is coupled to the cartridge having the needle piercing the sealing.
- the dosing means the metered amount of medication is driven into the syringe.
- the sy- ringe is then ready for injection after being removed from the cartridge.
- Fig. 1 is an exploded perspective view of the medication delivery device.
- Fig 2 is a cross-sectional view showing part of the medication delivery device, 2a immediately after assembling before the first injection, and 2b after some time of use
- Fig 3 is a cross-sectional view showing the cartridge before assembling of the medication delivery device
- a medication delivery device in accordance with the present invention is identified generally by the numeral 20 in Fig 1 and 2 Medication delivery device 20 includes a dosing assembly 6, and cartridge assembly 1 , a needle assembly 16 and a cap 14
- the dosing assembly 6 is illustrated in Fig 1 and 2 It is understood, however, that the dosing assembly 6 according to the invention may be any suitable dosing unit including plunger means, and accordingly, that variations from the depicted embodiment may be provided, and are considered to be within the scope of this invention
- the dosing assembly 6 includes a cylindrical housing surrounding the plunger means 17 of the dosing unit and having opposed proximal and distal ends
- the plunger means comprises a rod element 7 which is adapted to engage the stopper 4 of the cartridge assembly 1
- the rod element 7 advances axially into the cartridge 5 during injections
- the dosing assembly may have any suitable driving means for advancing the rod element 7
- the dosing unit 6 preferably also comprises scale means 10 indicating the dosing quantity selected by activating the dose setting means 9 for defining specified se- lected doses of medication to be delivered
- the selected dose may be delivered by actuating the actuator button 18
- the actuator button is part of the driving means of the dosing assembly exerting its force on the rod element 7
- the dosing assembly further comprises coupling means 8 adapted for engagement with the cartridge assembly.
- the coupling means 8 may be internal or external couplings. In a preferred embodiment the coupling 8 is an internal coupling.
- the cartridge assembly 1 is illustrated in Fig. 1 and 2, and in greater detail in Fig. 3.
- cartridge assembly 1 includes a moulded cartridge 5 extending from proximal end 21 to distal end 22.
- coupling means 2 for releasably mounting a needle assembly 1 1.
- coupling means 3 for mounting a dosing assembly 6. The coupling means are as described above.
- Cartridge 5 also comprises a stopper 4 in sliding fluid tight engagement within said cartridge 5.
- the stopper 4 is adapted to receive the plunger means, such as a rod element 7 of the dosing assembly 6.
- the cartridge assembly 1 may further comprise a housing for protecting some or all of the cartridge 5.
- the cartridge assembly 1 includes a housing, one or both of the couplings 2, 3 of the cartridge may be moulded unitarily with the housing.
- At least one of the couplings 2, 3 is moulded unitarily with the cartridge 5, minimising the total number of parts of the device and thereby the production costs. Also, a very precise coupling is obtained, since no further steps are to be taken to attach the coupling means to the catridge.
- the cartridge 5 may have integrally moulded reinforcements of the cartridge wall.
- the depicted cartridge 5 is cylindrical having couplings 2, 3 at opposed ends.
- the cartridge may obtain any suitable form and the cross-section may be circular or non-circular, such as substantially triangular or oval.
- the couplings 2, 3 are opposing each other having the same axis.
- the axis of coupling 2 may be arranged to be separate from coupling 3, that is in any angle with respect to the axis of coupling 3.
- the axis of coupling 2 may be perpendicular to the axis of coupling 3, or they may be parallel but not overlapping.
- a suitable choice of material allows the cartridge to be at least partly transparent, whereby the user can see whether any content, such as a liquid is left in the cartridge.
- the coupling means 3 is an external thread, whereas the coupling means 2 is a recess for a snap lock of the needle assembly. Both coupling means are moulded unitarily with the cartridge.
- the device according to the invention may include a protective cap 14 that is re- movably mounted over the cartridge assembly 1 and/or the needle 11 and which is removed before injection of the medication in the cartridge 5.
- the cap further ensures that the content of the cartridge is protected against sunlight.
- the various parts of the medication delivery device are advantageously made of plastics, e.g. by injection moulding.
- the medication delivery device 20 may further comprise any appropriate needle assembly 1 1 , such as a double ended needle 13 having opposed proximal and distal points and a lumen extending axially therebetween.
- any appropriate needle assembly 1 1 such as a double ended needle 13 having opposed proximal and distal points and a lumen extending axially therebetween.
- a mounting hub 12 is engaged on the needle 13 and is removably connected to the coupling means 2 at the needle end of the cartridge assembly.
- the relative location of the mounting hub 12 ensures that the proximal point of the needle 13 will pierce the sealing when the mounting hub 12 is engaged with the coupling means 2 on the cartridge assembly 1.
- the needle assembly 1 1 may further comprise a removable shield or cap 15 for protecting against accidental needle sticks.
- the device according to the invention is suitable for delivering pre-set dosages of insulin, it is however understood that the device is suitable for the injection of pre-set dosages of other liquids.
- the user will set the dose by means of the dose setting means 9.
- the cap 14 Before activating the actuator button 18 the cap 14 must be removed from the cartridge assembly 1 whereby the device 20 is prepared for an injection.
- the injection is effected by activating the actuator button 18, which again will effect the stopper 4 to be moved towards the needle at the sealed end 22 of the cartridge 5, thereby deliv- ering the desired pre-set dosage.
- a subsequent dosage of medication will be set in exactly the same manner as described above. However, for such a subsequent dosage, the rod element 7 and the stopper 4 will be in a partly advanced position as starting point. Dose setting and injections can be carried out until all of the medication has been used.
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Coating Apparatus (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Abstract
Description
Claims
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020017000299A KR20010053438A (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
CA002336729A CA2336729A1 (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
EP99931026A EP1094858B1 (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
DE69911966T DE69911966T2 (en) | 1998-07-08 | 1999-07-05 | A DISCHARGE DEVICE AND RELATED CARTRIDGE |
JP2000558864A JP2002520098A (en) | 1998-07-08 | 1999-07-05 | Drug release device and cartridge assembly used therein |
HU0102524A HUP0102524A3 (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
BR9911930-7A BR9911930A (en) | 1998-07-08 | 1999-07-05 | Medicine dispensing device, and, cartridge assembly for use in the same |
IL14052699A IL140526A0 (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
AT99931026T ATE251478T1 (en) | 1998-07-08 | 1999-07-05 | A DISCHARGE DEVICE AND ASSOCIATED CARTRIDGE |
AU47696/99A AU4769699A (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
PL99345360A PL345360A1 (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
NO20010091A NO20010091L (en) | 1998-07-08 | 2001-01-05 | Medical delivery device and a cartridge assembly for use therewith |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199800910 | 1998-07-08 | ||
DKPA199800910 | 1998-07-08 | ||
DKPA199801501 | 1998-11-17 | ||
DKPA199801501 | 1998-11-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000002606A1 true WO2000002606A1 (en) | 2000-01-20 |
Family
ID=26064887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DK1999/000387 WO2000002606A1 (en) | 1998-07-08 | 1999-07-05 | A medication delivery device and a cartridge assembly for use in the same |
Country Status (16)
Country | Link |
---|---|
US (1) | US6582408B1 (en) |
EP (1) | EP1094858B1 (en) |
JP (1) | JP2002520098A (en) |
KR (1) | KR20010053438A (en) |
CN (1) | CN1308551A (en) |
AT (1) | ATE251478T1 (en) |
AU (1) | AU4769699A (en) |
BR (1) | BR9911930A (en) |
CA (1) | CA2336729A1 (en) |
DE (1) | DE69911966T2 (en) |
HU (1) | HUP0102524A3 (en) |
IL (1) | IL140526A0 (en) |
NO (1) | NO20010091L (en) |
PL (1) | PL345360A1 (en) |
WO (1) | WO2000002606A1 (en) |
ZA (1) | ZA200100181B (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2003011370A2 (en) * | 2001-07-30 | 2003-02-13 | Tecpharma Licensing Ag | Locking device for connecting housing sections of an administration appliance |
US7309327B2 (en) | 2001-07-30 | 2007-12-18 | Tecpharma Licensing Ag | Administering apparatus comprising a rotational block |
US7628773B2 (en) | 2001-07-30 | 2009-12-08 | Tecpharma Licensing Ag | Reservoir module comprising a piston rod |
US7828779B2 (en) | 2001-12-21 | 2010-11-09 | Tecpharma Licensing Ag | Injection apparatus with an end position-blocked dosage setting member |
US8007476B2 (en) | 2001-07-30 | 2011-08-30 | Tecpharma Licensing Ag | Administering apparatus comprising a dosing device |
US11607490B2 (en) | 2016-11-01 | 2023-03-21 | Sanofi-Aventis Deutschland Gmbh | Volume measuring arrangement |
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DE20112501U1 (en) * | 2001-07-30 | 2002-12-19 | Disetronic Licensing Ag | Locking lock for connecting housing parts of an injection or infusion device |
PL366787A1 (en) * | 2001-08-27 | 2005-02-07 | Novo Nordisk A/S | A cartridge and a medical delivery system accommodating such a cartridge |
US6929619B2 (en) * | 2002-08-02 | 2005-08-16 | Liebel-Flarshiem Company | Injector |
EP2037987B1 (en) | 2006-06-30 | 2019-09-04 | Novo Nordisk A/S | A medical delivery system comprising a coding mechanism |
US8613731B2 (en) * | 2006-07-15 | 2013-12-24 | Novo Nordisk A/S | Medical delivery system with asymmetrical coding means |
ATE497397T1 (en) * | 2006-07-15 | 2011-02-15 | Novo Nordisk As | MEDICAL DISPENSING SYSTEM WITH ROTATABLE ENCRYPTION ELEMENT |
ATE493162T1 (en) * | 2006-08-28 | 2011-01-15 | Novo Nordisk As | AXIAL LOCKABLE AND ROTATION OPEN MEDICATION ADMINISTRATION SYSTEM |
CN101557850A (en) * | 2006-11-17 | 2009-10-14 | 诺沃-诺迪斯克有限公司 | A medical delivery system comprising a coding mechanism between dosing assembly and medicament container |
DE602007014411D1 (en) | 2006-11-21 | 2011-06-16 | Novo Nordisk As | MEDICAL DISPENSING SYSTEM WITH LOCKING RING WITH L-SHAPED NUTS |
US8454560B2 (en) | 2006-12-05 | 2013-06-04 | Mallinckrodt Llc | Syringe mount for a medical fluid injector |
WO2008071804A1 (en) | 2006-12-15 | 2008-06-19 | Novo Nordisk A/S | A medical delivery system comprising a container and a dosing assembly with radially moving fastening means |
EP2091600B1 (en) * | 2006-12-21 | 2019-02-20 | Novo Nordisk A/S | A syringe device |
KR100806567B1 (en) * | 2007-07-18 | 2008-02-28 | 이지성 | Devices for gauging dosage |
DE102008059673A1 (en) * | 2008-11-26 | 2010-05-27 | Bayer Schering Pharma Aktiengesellschaft | Cartridge, a drug dispenser containing the cartridge and uses of the cartridge and the drug dispenser |
EP2560709B1 (en) * | 2010-04-23 | 2020-11-04 | Sanofi-Aventis Deutschland GmbH | Cartridge assembly having shared fastening means and drug delivery device |
US9022988B1 (en) | 2010-05-07 | 2015-05-05 | Kavan J. Shaban | System and method for controlling a self-injector device |
US8672883B2 (en) | 2011-07-11 | 2014-03-18 | C. Garyen Denning | Fluid delivery device and methods |
CA2841368A1 (en) * | 2011-08-02 | 2013-02-07 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and cartridge to be interconnected therewith |
US8834449B2 (en) | 2012-01-23 | 2014-09-16 | Ikomed Technologies, Inc. | Mixing syringe |
US9751056B2 (en) | 2012-01-23 | 2017-09-05 | Merit Medical Systems, Inc. | Mixing syringe |
TR201908158T4 (en) * | 2012-08-31 | 2019-06-21 | Sanofi Aventis Deutschland | Medical device with shockproof housing. |
US10251964B2 (en) | 2016-08-23 | 2019-04-09 | Drma Group International Llc | Self-disinfecting needleless device |
US10195110B2 (en) | 2016-09-08 | 2019-02-05 | Drma Group International Llc | Capping device for disinfecting medical container |
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WO2018129443A1 (en) * | 2017-01-09 | 2018-07-12 | Cook Biotech Incorporated | Lyophilizer container and method of use thereof |
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- 1999-07-05 HU HU0102524A patent/HUP0102524A3/en unknown
- 1999-07-05 BR BR9911930-7A patent/BR9911930A/en not_active Application Discontinuation
- 1999-07-05 CA CA002336729A patent/CA2336729A1/en not_active Abandoned
- 1999-07-05 WO PCT/DK1999/000387 patent/WO2000002606A1/en not_active Application Discontinuation
- 1999-07-05 CN CN99808405A patent/CN1308551A/en active Pending
- 1999-07-05 JP JP2000558864A patent/JP2002520098A/en not_active Withdrawn
- 1999-07-05 DE DE69911966T patent/DE69911966T2/en not_active Revoked
- 1999-07-05 EP EP99931026A patent/EP1094858B1/en not_active Revoked
- 1999-07-05 KR KR1020017000299A patent/KR20010053438A/en not_active Application Discontinuation
- 1999-07-05 PL PL99345360A patent/PL345360A1/en unknown
- 1999-07-08 US US09/349,748 patent/US6582408B1/en not_active Expired - Fee Related
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- 2001-01-08 ZA ZA200100181A patent/ZA200100181B/en unknown
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Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2003011370A2 (en) * | 2001-07-30 | 2003-02-13 | Tecpharma Licensing Ag | Locking device for connecting housing sections of an administration appliance |
WO2003011370A3 (en) * | 2001-07-30 | 2003-10-23 | Tecpharma Licensing Ag | Locking device for connecting housing sections of an administration appliance |
US7309327B2 (en) | 2001-07-30 | 2007-12-18 | Tecpharma Licensing Ag | Administering apparatus comprising a rotational block |
US7377912B2 (en) | 2001-07-30 | 2008-05-27 | Tecpharma Licensing Ag | Latching block for connecting casing sections of an administering apparatus |
US7628773B2 (en) | 2001-07-30 | 2009-12-08 | Tecpharma Licensing Ag | Reservoir module comprising a piston rod |
US8007476B2 (en) | 2001-07-30 | 2011-08-30 | Tecpharma Licensing Ag | Administering apparatus comprising a dosing device |
US8545456B2 (en) | 2001-07-30 | 2013-10-01 | Tecpharma Licensing Ag | Administering apparatus comprising a rotational block |
US8568366B2 (en) | 2001-07-30 | 2013-10-29 | Tecpharma Licensing Ag | Reservoir module for an administering apparatus |
US8939944B2 (en) | 2001-07-30 | 2015-01-27 | Tecpharma Licensing Ag | Reservoir module comprising a piston rod |
US9205189B2 (en) | 2001-07-30 | 2015-12-08 | Tecpharma Licensing Ag | Reservoir module comprising a piston rod |
US7828779B2 (en) | 2001-12-21 | 2010-11-09 | Tecpharma Licensing Ag | Injection apparatus with an end position-blocked dosage setting member |
US11607490B2 (en) | 2016-11-01 | 2023-03-21 | Sanofi-Aventis Deutschland Gmbh | Volume measuring arrangement |
Also Published As
Publication number | Publication date |
---|---|
ZA200100181B (en) | 2001-07-23 |
PL345360A1 (en) | 2001-12-17 |
DE69911966T2 (en) | 2004-07-22 |
DE69911966D1 (en) | 2003-11-13 |
JP2002520098A (en) | 2002-07-09 |
EP1094858A1 (en) | 2001-05-02 |
IL140526A0 (en) | 2002-02-10 |
CA2336729A1 (en) | 2000-01-20 |
BR9911930A (en) | 2002-04-23 |
EP1094858B1 (en) | 2003-10-08 |
NO20010091D0 (en) | 2001-01-05 |
NO20010091L (en) | 2001-03-06 |
HUP0102524A2 (en) | 2001-11-28 |
KR20010053438A (en) | 2001-06-25 |
US6582408B1 (en) | 2003-06-24 |
CN1308551A (en) | 2001-08-15 |
ATE251478T1 (en) | 2003-10-15 |
HUP0102524A3 (en) | 2001-12-28 |
AU4769699A (en) | 2000-02-01 |
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