WO2000000622A3 - Human oxidoreductase proteins - Google Patents

Human oxidoreductase proteins Download PDF

Info

Publication number
WO2000000622A3
WO2000000622A3 PCT/US1999/014711 US9914711W WO0000622A3 WO 2000000622 A3 WO2000000622 A3 WO 2000000622A3 US 9914711 W US9914711 W US 9914711W WO 0000622 A3 WO0000622 A3 WO 0000622A3
Authority
WO
WIPO (PCT)
Prior art keywords
horp
oxidoreductase proteins
human oxidoreductase
provides
proteins
Prior art date
Application number
PCT/US1999/014711
Other languages
French (fr)
Other versions
WO2000000622A2 (en
Inventor
Olga Bandman
Jennifer L Hillman
Y Tom Tang
Preeti Lal
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Original Assignee
Incyte Pharma Inc
Olga Bandman
Jennifer L Hillman
Y Tom Tang
Preeti Lal
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Olga Bandman, Jennifer L Hillman, Y Tom Tang, Preeti Lal, Neil C Corley, Karl J Guegler, Gina A Gorgone, Mariah R Baughn filed Critical Incyte Pharma Inc
Priority to JP2000557375A priority Critical patent/JP2002519034A/en
Priority to EP99932044A priority patent/EP1092032A2/en
Priority to CA002331380A priority patent/CA2331380A1/en
Priority to AU48437/99A priority patent/AU4843799A/en
Publication of WO2000000622A2 publication Critical patent/WO2000000622A2/en
Publication of WO2000000622A3 publication Critical patent/WO2000000622A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides human oxidoreductase proteins (HORP) and polynucleotides which identify and encode HORP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HORP.
PCT/US1999/014711 1998-06-30 1999-06-29 Human oxidoreductase proteins WO2000000622A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000557375A JP2002519034A (en) 1998-06-30 1999-06-29 Human oxidoreductase protein
EP99932044A EP1092032A2 (en) 1998-06-30 1999-06-29 Human oxidoreductase proteins
CA002331380A CA2331380A1 (en) 1998-06-30 1999-06-29 Human oxidoreductase proteins
AU48437/99A AU4843799A (en) 1998-06-30 1999-06-29 Human oxidoreductase proteins

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9117798P 1998-06-30 1998-06-30
US60/091,177 1998-06-30
US15524198P 1998-07-16 1998-07-16
US60/155,241 1998-07-16

Publications (2)

Publication Number Publication Date
WO2000000622A2 WO2000000622A2 (en) 2000-01-06
WO2000000622A3 true WO2000000622A3 (en) 2000-04-20

Family

ID=26783679

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/014711 WO2000000622A2 (en) 1998-06-30 1999-06-29 Human oxidoreductase proteins

Country Status (5)

Country Link
EP (1) EP1092032A2 (en)
JP (1) JP2002519034A (en)
AU (1) AU4843799A (en)
CA (1) CA2331380A1 (en)
WO (1) WO2000000622A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1035207A1 (en) * 1999-03-09 2000-09-13 MultiGene Biotech GmbH cDNA molecules of the members of gene family encoding human fatty acid desaturases and their use in diagnosis and therapy
EP1280916A2 (en) * 2000-04-28 2003-02-05 Millennium Pharmaceuticals, Inc. 26343, a novel human oxidoreductase and uses therefor
EP1320585A2 (en) * 2000-09-29 2003-06-25 Incyte Genomics, Inc. Oxidoreductases

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0712932A2 (en) * 1994-11-18 1996-05-22 Sumitomo Chemical Company, Limited A human flavin-containing monooxygenase
WO1998020137A1 (en) * 1996-11-07 1998-05-14 Inctye Pharmaceuticals, Inc. Human squalene epoxidase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0712932A2 (en) * 1994-11-18 1996-05-22 Sumitomo Chemical Company, Limited A human flavin-containing monooxygenase
WO1998020137A1 (en) * 1996-11-07 1998-05-14 Inctye Pharmaceuticals, Inc. Human squalene epoxidase

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1986, CLAUSEN, N. ET AL.: "Determination of L-asparagine activity in serum by thin-layer chromatography application to the treatment of acute lymphoblastic leukemia.", XP002119912 *
DATABASE EMBL - EMEST2 19 January 1998 (1998-01-19), STRAUSBERG, R. ET AL.: "ny69g04.s1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE:1283574.", XP002119911 *
DATABASE EMBL - EMEST2 19 January 1998 (1998-01-19), STRAUSBERG, R.: "nx94a04.s1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE:1269870.", XP002119910 *
DATABASE EMBL - EMEST26 25 August 1996 (1996-08-25), TAKEDA, J.: "similar to N-terminal asparagine amidohydrolase.", XP002119909 *
GRIGORYEV, S. ET AL.: "A mouse amidase specific for N-terminal asparaginase - the gene, the enzyme, and their function in the N-end rule pathway.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 45, 8 November 1996 (1996-11-08), pages 28521 - 32, XP002116471 *
STEWART, A.E. ET AL.: "The sequence of porcine protein NH2-terminal asparagine amidohydrolase a new component of the N-end rule pathway.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 1, 6 January 1995 (1995-01-06), pages 25 - 8, XP002116472 *

Also Published As

Publication number Publication date
WO2000000622A2 (en) 2000-01-06
JP2002519034A (en) 2002-07-02
EP1092032A2 (en) 2001-04-18
AU4843799A (en) 2000-01-17
CA2331380A1 (en) 2000-01-06

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