WO1999064869A3 - Back pain diagnosis and apparatus for use therein - Google Patents

Back pain diagnosis and apparatus for use therein Download PDF

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Publication number
WO1999064869A3
WO1999064869A3 PCT/GB1999/001823 GB9901823W WO9964869A3 WO 1999064869 A3 WO1999064869 A3 WO 1999064869A3 GB 9901823 W GB9901823 W GB 9901823W WO 9964869 A3 WO9964869 A3 WO 9964869A3
Authority
WO
WIPO (PCT)
Prior art keywords
back pain
diagnosis
low back
processes
sciatica
Prior art date
Application number
PCT/GB1999/001823
Other languages
French (fr)
Other versions
WO1999064869A2 (en
Inventor
Thomas John Baldwin
Khai Sing Lam
Original Assignee
Univ Nottingham
Thomas John Baldwin
Khai Sing Lam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nottingham, Thomas John Baldwin, Khai Sing Lam filed Critical Univ Nottingham
Priority to AU42797/99A priority Critical patent/AU4279799A/en
Publication of WO1999064869A2 publication Critical patent/WO1999064869A2/en
Publication of WO1999064869A3 publication Critical patent/WO1999064869A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The intervertebral disc is implicated as a source of symptoms of low back pain and sciatica. Degenerative disc disease and inflammatory processes may result in low back pain. The invention identifies the involvement of lysozyme C and tyrosine phosphorylation in low back pain, sciatica and other joint diseases and provides methods and apparatus for diagnosis and uses of these substances, and processes and substances influencing these processes in the treatment and diagnosis of such diseases and conditions.
PCT/GB1999/001823 1998-06-09 1999-06-09 Back pain diagnosis and apparatus for use therein WO1999064869A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU42797/99A AU4279799A (en) 1998-06-09 1999-06-09 Back pain diagnosis and apparatus for use therein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9812290.6A GB9812290D0 (en) 1998-06-09 1998-06-09 Back pain diagnosis
GB9812290.6 1998-06-09

Publications (2)

Publication Number Publication Date
WO1999064869A2 WO1999064869A2 (en) 1999-12-16
WO1999064869A3 true WO1999064869A3 (en) 2000-03-02

Family

ID=10833380

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/001823 WO1999064869A2 (en) 1998-06-09 1999-06-09 Back pain diagnosis and apparatus for use therein

Country Status (3)

Country Link
AU (1) AU4279799A (en)
GB (1) GB9812290D0 (en)
WO (1) WO1999064869A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7452351B2 (en) 2004-04-16 2008-11-18 Kyphon Sarl Spinal diagnostic methods and apparatus
US7824390B2 (en) 2004-04-16 2010-11-02 Kyphon SÀRL Spinal diagnostic methods and apparatus

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132830A2 (en) * 1983-07-25 1985-02-13 EASTMAN KODAK COMPANY (a New Jersey corporation) Dry analytical element for alkaline phosphatase assay
DD226017A1 (en) * 1984-06-27 1985-08-14 Adw Ddr TEST STRIPS FOR DETECTING LYSOCYM (EC 3.2.1.17)
EP0277540A1 (en) * 1987-01-23 1988-08-10 Hoechst Aktiengesellschaft Method for the determination of lysozyme activity
EP0381450A2 (en) * 1989-01-31 1990-08-08 Hybritech Incorporated Assay for bone alkaline phosphatase
WO1992010760A1 (en) * 1990-11-30 1992-06-25 Monoclonetics International, Incorporated Methods for the diagnosis of chronic lower back and cervical pain
WO1993003377A1 (en) * 1991-07-31 1993-02-18 Ziltener Hermann J Method for the detection of phosphotyrosine residues
EP0741144A1 (en) * 1994-11-11 1996-11-06 International Reagents Corporation Antiannexin-v monoclonal antibody, process for producing the same, and use therof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132830A2 (en) * 1983-07-25 1985-02-13 EASTMAN KODAK COMPANY (a New Jersey corporation) Dry analytical element for alkaline phosphatase assay
DD226017A1 (en) * 1984-06-27 1985-08-14 Adw Ddr TEST STRIPS FOR DETECTING LYSOCYM (EC 3.2.1.17)
EP0277540A1 (en) * 1987-01-23 1988-08-10 Hoechst Aktiengesellschaft Method for the determination of lysozyme activity
EP0381450A2 (en) * 1989-01-31 1990-08-08 Hybritech Incorporated Assay for bone alkaline phosphatase
WO1992010760A1 (en) * 1990-11-30 1992-06-25 Monoclonetics International, Incorporated Methods for the diagnosis of chronic lower back and cervical pain
WO1993003377A1 (en) * 1991-07-31 1993-02-18 Ziltener Hermann J Method for the detection of phosphotyrosine residues
EP0741144A1 (en) * 1994-11-11 1996-11-06 International Reagents Corporation Antiannexin-v monoclonal antibody, process for producing the same, and use therof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Columbus, Ohio, US; XP002900782 *
DATABASE WPI Derwent World Patents Index; XP002900781 *
DATABASE WPI Derwent World Patents Index; XP002900783 *
DATABASE WPI Derwent World Patents Index; XP002900784 *
DATABASE WPI Derwent World Patents Index; XP002900785 *

Also Published As

Publication number Publication date
AU4279799A (en) 1999-12-30
WO1999064869A2 (en) 1999-12-16
GB9812290D0 (en) 1998-08-05

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