IT1290781B1 - ACTIVE THERAPEUTIC AGENT FOR THE TREATMENT OF NEURONAL DEGENERATIVE DISEASES. - Google Patents
ACTIVE THERAPEUTIC AGENT FOR THE TREATMENT OF NEURONAL DEGENERATIVE DISEASES.Info
- Publication number
- IT1290781B1 IT1290781B1 IT96RM000364A ITRM960364A IT1290781B1 IT 1290781 B1 IT1290781 B1 IT 1290781B1 IT 96RM000364 A IT96RM000364 A IT 96RM000364A IT RM960364 A ITRM960364 A IT RM960364A IT 1290781 B1 IT1290781 B1 IT 1290781B1
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- therapeutic agent
- degenerative diseases
- active therapeutic
- neuronal degenerative
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000364A IT1290781B1 (en) | 1996-05-28 | 1996-05-28 | ACTIVE THERAPEUTIC AGENT FOR THE TREATMENT OF NEURONAL DEGENERATIVE DISEASES. |
EP97925266A EP0914131A1 (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
JP54197097A JP3725172B2 (en) | 1996-05-28 | 1997-05-23 | A therapeutic agent active in the treatment of neurodegenerative diseases comprising uridine |
HU0000124A HUP0000124A3 (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
CA002255748A CA2255748C (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
BR9709379-3A BR9709379A (en) | 1996-05-28 | 1997-05-23 | Use of uridine, and, composition for the treatment of disorders of the nervous system due to the selective degeneration of neuronal or glial cells in mammals. |
AU30468/97A AU3046897A (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
PCT/IT1997/000117 WO1997045127A1 (en) | 1996-05-28 | 1997-05-23 | Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000364A IT1290781B1 (en) | 1996-05-28 | 1996-05-28 | ACTIVE THERAPEUTIC AGENT FOR THE TREATMENT OF NEURONAL DEGENERATIVE DISEASES. |
US1854396P | 1996-05-29 | 1996-05-29 |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM960364A0 ITRM960364A0 (en) | 1996-05-28 |
ITRM960364A1 ITRM960364A1 (en) | 1997-11-28 |
IT1290781B1 true IT1290781B1 (en) | 1998-12-10 |
Family
ID=26332100
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT96RM000364A IT1290781B1 (en) | 1996-05-28 | 1996-05-28 | ACTIVE THERAPEUTIC AGENT FOR THE TREATMENT OF NEURONAL DEGENERATIVE DISEASES. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0914131A1 (en) |
AU (1) | AU3046897A (en) |
IT (1) | IT1290781B1 (en) |
WO (1) | WO1997045127A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8143234B2 (en) | 1998-07-31 | 2012-03-27 | Massachusetts Institute Of Technology | Uridine administration improves phosphatide synthesis, synaptic transmission and cognitive function |
US8314064B2 (en) * | 1998-07-31 | 2012-11-20 | Massachusetts Institute Of Technology | Uridine administration stimulates membrane production |
DK2329829T3 (en) * | 1998-07-31 | 2014-07-21 | Massachusetts Inst Technology | Utilization of uridine in combination with choline for the treatment of neurological disorders |
US20050203053A1 (en) * | 1999-07-30 | 2005-09-15 | Wurtman Richard J. | Uridine administration improves phosphatide synthesis, synaptic transmission and cogntive function |
US8518882B2 (en) * | 1998-07-31 | 2013-08-27 | Massachusetts Institute Of Technology | Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same |
US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
US7807654B2 (en) | 1998-08-31 | 2010-10-05 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
US7915233B1 (en) | 1998-08-31 | 2011-03-29 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
PL209031B1 (en) * | 2001-04-30 | 2011-07-29 | Trommsdorff Arzneimittel | Pharmaceutically active uridine esters |
US6767202B2 (en) | 2001-12-18 | 2004-07-27 | 3M Innovative Properties Company | Tooling with helical coils for structured surface articles |
CA2566612C (en) | 2004-05-13 | 2015-06-30 | Massachusetts Institute Of Technology | Uridine effects on dopamine release |
WO2006031683A2 (en) * | 2004-09-15 | 2006-03-23 | Massachusetts Institute Of Technology | Compositions containing uridine, and methods utilizing same |
US8318798B2 (en) | 2005-11-24 | 2012-11-27 | National University Corporation Hokkaldo University | Therapeutic agent for neurodegenerative disease |
WO2009059306A1 (en) | 2007-11-02 | 2009-05-07 | Massachusetts Institute Of Technology | Uridine dietary supplementation compliance methods and use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1178044B (en) * | 1984-10-09 | 1987-09-03 | Polifarma Spa | PHARMACEUTICAL ACTIVE AGENT FOR THE TREATMENT OF CEREBRAL DISEASES BASED ON URIDINE |
IT1219667B (en) * | 1988-06-21 | 1990-05-24 | Polifarma Spa | USE OF URIDINE IN THE PHARMACOLOGICAL TREATMENT OF DISORDERS DUE TO ALTERATED DOPAMINERGIC BALANCE |
IT1241984B (en) * | 1990-06-13 | 1994-02-02 | Polifarma Spa | USE OF URIDINE IN THE PHARMACOLOGICAL TREATMENT OF PERIPHERAL COMPLICATIONS OF DIABETES |
JPH05304951A (en) * | 1992-04-06 | 1993-11-19 | N T Sci:Kk | Culture solution for early embryo and embryonic stem cell |
-
1996
- 1996-05-28 IT IT96RM000364A patent/IT1290781B1/en active IP Right Grant
-
1997
- 1997-05-23 AU AU30468/97A patent/AU3046897A/en not_active Abandoned
- 1997-05-23 EP EP97925266A patent/EP0914131A1/en not_active Ceased
- 1997-05-23 WO PCT/IT1997/000117 patent/WO1997045127A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU3046897A (en) | 1998-01-05 |
ITRM960364A1 (en) | 1997-11-28 |
ITRM960364A0 (en) | 1996-05-28 |
WO1997045127A1 (en) | 1997-12-04 |
EP0914131A1 (en) | 1999-05-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted |