WO1999064596A3 - Proteins regulating gene expression - Google Patents

Proteins regulating gene expression Download PDF

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Publication number
WO1999064596A3
WO1999064596A3 PCT/US1999/013281 US9913281W WO9964596A3 WO 1999064596 A3 WO1999064596 A3 WO 1999064596A3 US 9913281 W US9913281 W US 9913281W WO 9964596 A3 WO9964596 A3 WO 9964596A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene expression
regulating gene
prge
proteins regulating
provides
Prior art date
Application number
PCT/US1999/013281
Other languages
French (fr)
Other versions
WO1999064596A2 (en
Inventor
Preeti Lal
Henry Yue
Y Tom Tang
Jennifer L Hillman
Olga Bandman
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Chandra Patterson
Dyung Aina M Lu
Original Assignee
Incyte Pharma Inc
Preeti Lal
Henry Yue
Y Tom Tang
Jennifer L Hillman
Olga Bandman
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Chandra Patterson
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Preeti Lal, Henry Yue, Y Tom Tang, Jennifer L Hillman, Olga Bandman, Neil C Corley, Karl J Guegler, Gina A Gorgone, Mariah R Baughn, Chandra Patterson, Dyung Aina M Lu filed Critical Incyte Pharma Inc
Priority to EP99927495A priority Critical patent/EP1086219A2/en
Priority to CA002329685A priority patent/CA2329685A1/en
Priority to AU44388/99A priority patent/AU4438899A/en
Priority to JP2000553586A priority patent/JP2002517246A/en
Publication of WO1999064596A2 publication Critical patent/WO1999064596A2/en
Publication of WO1999064596A3 publication Critical patent/WO1999064596A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides human proteins regulating gene expression (PRGE) and polynucleotides which identify and encode PRGE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PRGE.
PCT/US1999/013281 1998-06-12 1999-06-11 Proteins regulating gene expression WO1999064596A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99927495A EP1086219A2 (en) 1998-06-12 1999-06-11 Proteins regulating gene expression
CA002329685A CA2329685A1 (en) 1998-06-12 1999-06-11 Proteins regulating gene expression
AU44388/99A AU4438899A (en) 1998-06-12 1999-06-11 Proteins regulating gene expression
JP2000553586A JP2002517246A (en) 1998-06-12 1999-06-11 Gene expression regulatory protein

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US8902998P 1998-06-12 1998-06-12
US60/089,029 1998-06-12
US9457598P 1998-07-29 1998-07-29
US60/094,575 1998-07-29
US10462498P 1998-10-14 1998-10-14
US60/104,624 1998-10-14

Publications (2)

Publication Number Publication Date
WO1999064596A2 WO1999064596A2 (en) 1999-12-16
WO1999064596A3 true WO1999064596A3 (en) 2000-04-06

Family

ID=27376173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/013281 WO1999064596A2 (en) 1998-06-12 1999-06-11 Proteins regulating gene expression

Country Status (5)

Country Link
EP (1) EP1086219A2 (en)
JP (1) JP2002517246A (en)
AU (1) AU4438899A (en)
CA (1) CA2329685A1 (en)
WO (1) WO1999064596A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001042291A2 (en) * 1999-12-10 2001-06-14 Curagen Corporation Polynucleotides and polypeptides encoded thereby
AU1214202A (en) * 2000-08-21 2002-03-04 Akzo Nobel Nv Coactivation of nuclear receptors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A1 (en) * 1993-11-12 1995-11-02 Kenichi Matsubara Gene signature

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A1 (en) * 1993-11-12 1995-11-02 Kenichi Matsubara Gene signature

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HILLIER L ET AL.: "Homo sapiens cDNA clone 743852, similar to TR:G300372 Cell Growth Regulating Nucleolar Protein", EMEST DATABASE ENTRY AA634416, ACCESSION NUMBER AA634416, 31 October 1997 (1997-10-31), XP002118339 *
HILLIER L ET AL: "Homo sapiens cDNA clone 366009, similar to TR:G300372 Cell Growth Regulating Nucleolar Protein", EMEST DATABASE ENTRY HSA63624, ACCESSION NUMBER AA063624, 25 September 1996 (1996-09-25), XP002118340 *
SU L ET AL: "LYAR, a novel nucliolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation", GENES AND DEVELOPMENT., vol. 7, 1993, COLD SPRING HARBOR LABORATORY PRESS, NEW YORK., US, pages 735 - 748, XP002118338 *

Also Published As

Publication number Publication date
JP2002517246A (en) 2002-06-18
EP1086219A2 (en) 2001-03-28
WO1999064596A2 (en) 1999-12-16
CA2329685A1 (en) 1999-12-16
AU4438899A (en) 1999-12-30

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