WO1999049035A3 - Insecticidal compounds from segestria florentina - Google Patents

Insecticidal compounds from segestria florentina Download PDF

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Publication number
WO1999049035A3
WO1999049035A3 PCT/GB1999/000907 GB9900907W WO9949035A3 WO 1999049035 A3 WO1999049035 A3 WO 1999049035A3 GB 9900907 W GB9900907 W GB 9900907W WO 9949035 A3 WO9949035 A3 WO 9949035A3
Authority
WO
WIPO (PCT)
Prior art keywords
seq
acid sequence
amino acid
segestria
florentina
Prior art date
Application number
PCT/GB1999/000907
Other languages
French (fr)
Other versions
WO1999049035A2 (en
Inventor
John David Windass
Andrew Nicholas Blake
Evgeny Vasilievich Grishin
Elene Daniilovna Nosyreva
Sergei Aleksandrovich Koslov
Alexei Valerievich Lipkin
Original Assignee
Zeneca Ltd
John David Windass
Andrew Nicholas Blake
Evgeny Vasilievich Grishin
Elene Daniilovna Nosyreva
Sergei Aleksandrovich Koslov
Alexei Valerievich Lipkin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU98105686/13A external-priority patent/RU98105686A/en
Application filed by Zeneca Ltd, John David Windass, Andrew Nicholas Blake, Evgeny Vasilievich Grishin, Elene Daniilovna Nosyreva, Sergei Aleksandrovich Koslov, Alexei Valerievich Lipkin filed Critical Zeneca Ltd
Priority to AU31563/99A priority Critical patent/AU3156399A/en
Publication of WO1999049035A2 publication Critical patent/WO1999049035A2/en
Publication of WO1999049035A3 publication Critical patent/WO1999049035A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

New insecticidal agents which comprise a polypeptide having a partial amino acid sequence: X?1ECMX2DX3TVCYIX4¿N (SEQ ID NO 3) or partial amino acid sequence: CENCWQYCDR (SEQ ID NO 4) where X?1, X2, X3 and X4¿ are variable amino acids; and a molecular weight of less than 6kDa, are described. Agents of this type may be obtainable from Segestria florentina or a fragment, variant or derivative thereof. Sequences encoding these toxins may be incorporated into insect viruses such as baculoviruses, or into recombinant plants in order to exert their toxic effect.
PCT/GB1999/000907 1998-03-26 1999-03-23 Insecticidal compounds from segestria florentina WO1999049035A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU31563/99A AU3156399A (en) 1998-03-26 1999-03-23 Insecticidal compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU98105686 1998-03-26
RU98105686/13A RU98105686A (en) 1998-03-26 INSECTICIDE COMPOUNDS

Publications (2)

Publication Number Publication Date
WO1999049035A2 WO1999049035A2 (en) 1999-09-30
WO1999049035A3 true WO1999049035A3 (en) 2000-01-20

Family

ID=20203962

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/000907 WO1999049035A2 (en) 1998-03-26 1999-03-23 Insecticidal compounds from segestria florentina

Country Status (2)

Country Link
AU (1) AU3156399A (en)
WO (1) WO1999049035A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20012564A1 (en) * 2001-12-05 2003-06-05 Pier Giorgio Righetti PROCEDURE FOR THE SELECTIVE ALKYLATION OF SH-GROUPS IN PROTEINS AND PEPTIDES IN THE STUDY OF COMPLEX PROTEIN MIXTURES
WO2011158242A2 (en) 2010-06-16 2011-12-22 Futuragene Israel Ltd. Pest -resistant plants containing a combination of a spider toxin and a chitinase

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0431829A1 (en) * 1989-11-29 1991-06-12 Agracetus, Inc. Insecticidal toxins in plants
WO1992016637A1 (en) * 1991-03-22 1992-10-01 Roussel-Uclaf Biological control agents
WO1998009522A1 (en) * 1996-09-04 1998-03-12 Nps Pharmaceuticals, Inc. Insecticidal peptides from segestria sp. spider venom

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0431829A1 (en) * 1989-11-29 1991-06-12 Agracetus, Inc. Insecticidal toxins in plants
WO1992016637A1 (en) * 1991-03-22 1992-10-01 Roussel-Uclaf Biological control agents
WO1998009522A1 (en) * 1996-09-04 1998-03-12 Nps Pharmaceuticals, Inc. Insecticidal peptides from segestria sp. spider venom

Also Published As

Publication number Publication date
WO1999049035A2 (en) 1999-09-30
AU3156399A (en) 1999-10-18

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