WO1999047172A3 - Compositions pharmaceutiques orales a prendre sans liquides et contenant des composes d'inclusion - Google Patents

Compositions pharmaceutiques orales a prendre sans liquides et contenant des composes d'inclusion Download PDF

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Publication number
WO1999047172A3
WO1999047172A3 PCT/EP1999/001540 EP9901540W WO9947172A3 WO 1999047172 A3 WO1999047172 A3 WO 1999047172A3 EP 9901540 W EP9901540 W EP 9901540W WO 9947172 A3 WO9947172 A3 WO 9947172A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquids
pharmaceutical compositions
inclusion complexes
taken
oral pharmaceutical
Prior art date
Application number
PCT/EP1999/001540
Other languages
English (en)
Other versions
WO1999047172A2 (fr
Inventor
Giancarlo Santus
Roberto Golzi
Caterina Lazzarini
Luciano Marcelloni
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Priority to AU29326/99A priority Critical patent/AU2932699A/en
Publication of WO1999047172A2 publication Critical patent/WO1999047172A2/fr
Publication of WO1999047172A3 publication Critical patent/WO1999047172A3/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des compositions pharmaceutiques destinées à une administration orale qui contiennent des composés d'inclusion et qui sont caractérisées par la libération rapide du principe actif et en ce qu'elles ne nécessitent pas l'utilisation de liquides pour l'administration, la salive présente dans la cavité orale servant à la dissolution du principe actif. Lesdites formulations sont particulièrement utiles pour augmenter la biodisponibilité des principes actifs qui sont insolubles ou légèrement solubles dans l'eau.
PCT/EP1999/001540 1998-03-13 1999-03-10 Compositions pharmaceutiques orales a prendre sans liquides et contenant des composes d'inclusion WO1999047172A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU29326/99A AU2932699A (en) 1998-03-13 1999-03-10 Oral pharmaceutical compositions to be taken without liquids, which contain inclusion complexes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI98A000511 1998-03-13
IT98MI000511A IT1298732B1 (it) 1998-03-13 1998-03-13 Composizioni farmaceutiche orali assumibili senza liquidi,contenenti complessi di inclusione

Publications (2)

Publication Number Publication Date
WO1999047172A2 WO1999047172A2 (fr) 1999-09-23
WO1999047172A3 true WO1999047172A3 (fr) 1999-11-11

Family

ID=11379303

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/001540 WO1999047172A2 (fr) 1998-03-13 1999-03-10 Compositions pharmaceutiques orales a prendre sans liquides et contenant des composes d'inclusion

Country Status (3)

Country Link
AU (1) AU2932699A (fr)
IT (1) IT1298732B1 (fr)
WO (1) WO1999047172A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN190018B (fr) * 1999-09-28 2003-05-31 Panacea Biotec Ltd
MXPA03001407A (es) * 2000-08-18 2003-06-06 Pharmacia Corp Formulacion oral de desintegracion rapida de un inhibidor de ciclooxigenasa-2.
TWI321054B (en) 2000-12-19 2010-03-01 California Inst Of Techn Compositions containing inclusion complexes
EP1258241A1 (fr) * 2001-05-16 2002-11-20 BIOPROGRESS S.p.A. Procédé permettant d'accroitre la biodisponibilité de nimesulide
EP2277551B1 (fr) 2002-09-06 2013-05-08 Cerulean Pharma Inc. Polymeres a base de cyclodextrine pour l'administration de medicament lies par liaison covalente
US8357377B2 (en) 2002-10-09 2013-01-22 Suzie Hwang Pun Cyclodextrin-based materials, compositions and uses related thereto
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス， インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
WO2014055493A1 (fr) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Procédés et systèmes s'appliquant à la précipitation de polymères et à la génération de particules

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449731A1 (fr) * 1990-03-28 1991-10-02 Laboratoires Crinex Composition pharmaceutique à administration perlinguale, antiinflammatoire et/ou analgésique
WO1991017774A1 (fr) * 1990-05-22 1991-11-28 Boehringer Ingelheim Italia S.P.A. Composes d'inclusion de nimesulide avec des cyclodextrines
EP0490193A1 (fr) * 1990-11-30 1992-06-17 MEDICE Chem.-Pharm. Fabrik Pütter GmbH & Co. KG Complexe d'un enantiomère actif de l'ibuprofen avec la cyclodextrine
WO1994002177A1 (fr) * 1992-07-28 1994-02-03 Boehringer Ingelheim Italia S.P.A. Procede de preparation de composes d'inclusion de la nimesulide avec des cyclodextrines
WO1995015155A1 (fr) * 1993-12-03 1995-06-08 Smithkline Beecham Farmaceutici S.P.A. Composition au gout dissimule contenant un complexe medicament/polymere
WO1997041843A2 (fr) * 1996-05-03 1997-11-13 Atp Avant-Garde Technologies & Product Chewing-gum medicamenteux possedant un gout agreable et contenant un complexe d'insertion
CN1176784A (zh) * 1997-07-24 1998-03-25 北京路德有限责任公司 对乙酰氨基酚咀嚼片的制造方法及其产品

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449731A1 (fr) * 1990-03-28 1991-10-02 Laboratoires Crinex Composition pharmaceutique à administration perlinguale, antiinflammatoire et/ou analgésique
WO1991017774A1 (fr) * 1990-05-22 1991-11-28 Boehringer Ingelheim Italia S.P.A. Composes d'inclusion de nimesulide avec des cyclodextrines
EP0490193A1 (fr) * 1990-11-30 1992-06-17 MEDICE Chem.-Pharm. Fabrik Pütter GmbH & Co. KG Complexe d'un enantiomère actif de l'ibuprofen avec la cyclodextrine
WO1994002177A1 (fr) * 1992-07-28 1994-02-03 Boehringer Ingelheim Italia S.P.A. Procede de preparation de composes d'inclusion de la nimesulide avec des cyclodextrines
WO1995015155A1 (fr) * 1993-12-03 1995-06-08 Smithkline Beecham Farmaceutici S.P.A. Composition au gout dissimule contenant un complexe medicament/polymere
WO1997041843A2 (fr) * 1996-05-03 1997-11-13 Atp Avant-Garde Technologies & Product Chewing-gum medicamenteux possedant un gout agreable et contenant un complexe d'insertion
CN1176784A (zh) * 1997-07-24 1998-03-25 北京路德有限责任公司 对乙酰氨基酚咀嚼片的制造方法及其产品

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EPODOC EUROPEAN PATENT OFFICE; 25 March 1998 (1998-03-25), XP002111791 *

Also Published As

Publication number Publication date
WO1999047172A2 (fr) 1999-09-23
ITMI980511A1 (it) 1999-09-13
AU2932699A (en) 1999-10-11
IT1298732B1 (it) 2000-02-02

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