WO1999047038A1 - Systeme de tubage - Google Patents

Systeme de tubage Download PDF

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Publication number
WO1999047038A1
WO1999047038A1 PCT/US1998/026399 US9826399W WO9947038A1 WO 1999047038 A1 WO1999047038 A1 WO 1999047038A1 US 9826399 W US9826399 W US 9826399W WO 9947038 A1 WO9947038 A1 WO 9947038A1
Authority
WO
WIPO (PCT)
Prior art keywords
endotracheal tube
intubation
insertion cord
fiberscope
stylet
Prior art date
Application number
PCT/US1998/026399
Other languages
English (en)
Inventor
Charles Allen Bashour
Original Assignee
Charles Allen Bashour
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charles Allen Bashour filed Critical Charles Allen Bashour
Priority to AU18196/99A priority Critical patent/AU1819699A/en
Priority to CA002289614A priority patent/CA2289614C/fr
Priority to US09/423,820 priority patent/US6432042B1/en
Publication of WO1999047038A1 publication Critical patent/WO1999047038A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/267—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the respiratory tract, e.g. laryngoscopes, bronchoscopes
    • A61B1/2676—Bronchoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/005—Flexible endoscopes
    • A61B1/0051—Flexible endoscopes with controlled bending of insertion part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0475—Tracheal tubes having openings in the tube
    • A61M16/0477—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
    • A61M16/0484—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids at the distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0434—Cuffs

Definitions

  • Applicant's invention relates to endoscopy and to instruments and methodologies which are useful in the performance of intubation procedures.
  • Background Information Intubation is the process by which an endotracheal tube is inserted into the trachea of an individual who requires assistance in breathing.
  • the need for intubation often arises from a cardiac and/or pulmonary arrest, or from trauma when the patient is unable to breath without outside intervention.
  • elective intubation may be involved in preparing a patient for surgery under general anesthesia when the capacity for independent breathing will be interrupted.
  • Intubation is a well-established procedure for obtaining an artificial airway, but is often difficult for the medical professional, and potentially dangerous (or, at least, ineffective) for the patient.
  • Properly negotiating the anatomy of the pharynx and larynx to ultimately place an endotracheal tube in the trachea for a proper intubation necessarily requires that the endotracheal tube pass through a patient's vocal cords, not a structure that is always visible at the time of intubation, and thus intubation is often a partially blind procedure that relies on imperfect, indirect methods for confirming proper endotracheal tube placement.
  • a laryngoscope is an instrument held with the left hand during intubation, and is used to divert the patient's tongue and epiglottis, thereby distorting the anatomy to expose the 2 vocal cords. Exposing the vocal cords makes an intubation (where the endotracheal tube must pass through the vocal cords and enter the trachea) at least possible. Often, however, even with the laryngoscope in an optimal position, the vocal cords cannot be visualized due to a small mouth opening, inability to flex the neck due to trauma or other reasons, or an anterior position of the larynx, and, therefore, placement of the endotracheal tube becomes a partially blind procedure. In fact, the most critical phase of intubation is that where the endotracheal tube is seen passing through the vocal cords and into the trachea. Without seeing this, an intubation becomes more difficult and may even be impossible.
  • Another indirect method for verifying proper placement of an endotracheal tube involves measuring carbon dioxide emissions from the endotracheal tube (to indicate that the endotracheal tube is in communication with the patient's lungs and, therefore, in a position for exhausting the carbon dioxide of respiration) .
  • the carbon dioxide detection method involves the expense of a disposable carbon dioxide sensor, and is susceptible to both "false positives” and “false negatives” under certain circumstances relating to the patient ' s gastric state and/or cardiac function at the time of intubation.
  • Another method of determining proper placement of an endotracheal tube is by x-ray verification. This involves radiation exposure which should be avoided when non-radiation methods are equally efficacious. Moreover, x-ray verification of proper endotracheal tube placement is time consuming and involves additional expense. In light of the limitations to indirect, post-intubation indication of proper endotracheal tube placement, it is highly desirable to insure that proper tracheal intubation has occurred in the first place, and even more desirable to confirm proper placement as the intubation is proceeding. Absolute assurance of correct endotracheal tube placement is only possible when the medical professional can actually watch the tube pass through the vocal cords and into the trachea, and see its position in the trachea.
  • an intubating airway (a temporary device that is placed in the patient's mouth to guide an endotracheal tube generally toward its intended target) is placed, and an endotracheal tube is then inserted into the passageway of the intubating airway.
  • the fiberscope is advanced (using both hands) through the endotracheal tube through the vocal cords and into the trachea.
  • the fiberscope as a guide wire, one of the medical professionals then advances the endotracheal tube over the fiberscope and (hopefully) into the trachea.
  • the long fiberscope insertion cord is then withdrawn while, holding the endotracheal tube in place .
  • the tube-first approach to fiberoptic intubation using presently available apparatuses is not without its limitations.
  • a common problem may occur when the fiberscope is advanced through the endotracheal tube.
  • the fiberscope tip may (and often does) pass through the "Murphy's eye" of the endotracheal tube.
  • the Murphy's eye is a lumen which opens through the side of the endotracheal tube near its distal end which is provided for preventing complete blockage 5 of the endotracheal tube, even if the distal opening somehow becomes blocked.
  • the pliable insertion cord of presently available fiberscopes can be easily displaced by the stiffer endotracheal tube, and the endotracheal tube may, therefore, be placed in the esophagus, even though the fiberoptic scope was initially in the trachea.
  • the medical professional first attempts to direct the fiberscope, with an endotracheal tube pre-loaded back on the most proximal segment of the insertion cord, fully into the trachea, after which the endotracheal tube is, as described before, advanced over the fiberscope, using the fiberscope essentially as a guide wire, into the trachea.
  • a lack of sufficient or moldable rigidity of the fiberscope often makes it quite difficult to direct the fiberscope along the intended pathway, even though the practitioner can see where the fiberscope is going.
  • the distal margins of the endotracheal tube may still impinge on laryngeal anatomy and be incapable of being advanced into the trachea, in part, because the highly flexible fiberscope, even if properly placed, may not be able to resist the deviating forces which act against the endotracheal tube.
  • the fiberscope would be of a new design, compared to currently known fiberscopes, and includes an insertion cord which is configured to prevent extension of its distal tip beyond the distal end of an endotracheal tube fitted thereon. To enhance the directional control of the fiberscope (e.g.
  • the insertion cord would be modified from currently available examples.
  • the insertion cord would include a malleable, rigidity enhancing member which will endow it both with the rigidity which is desirable, to aid in controllably advancing the cord along its intended path and the shape memory which will allow the user to form segments of its length to conform to the pathway which it must traverse during the intubation.
  • the newly designed fiberscope would be easier to clean and maintain, and likely be available at a lower cost. It could also be made to exhibit a smaller cross section and thus be suitable for a wider range of endotracheal tube sizes, including those for pediatric use.
  • the fiberscope designed according to the present invention, is what might better be described as an endotracheal tube "Endoscopic Stylet" for it serves both functions of a fiberoptic endoscope for visualization and manipulation of the intubation procedure and those of a stylet to help conform the endotracheal tube to any configuration for somewhat forcibly advancing the apparatus along a desired path, even against resistance from existing anatomical features. Because of these features, and the fact that the endoscopic stylet and its intended endotracheal tube mate would be of approximate equal length and designed for use, relative to each other, as static components of a single unit during an intubation procedure, the system would be used by a single practitioner.
  • Adding the 9 feature of an remotely-controlled, articulating terminal segment for the insertion cord of the endoscopic stylet would enable the practitioner to maneuver the distal end of the associated endotracheal tube which is fitted thereon, thus further enhancing the ease of use and reliability of the endoscopic stylet system.
  • No existing instrument allows its user to visualize the precise position of the distal end of the endotracheal tube relative to surrounding anatomy as the endotracheal tube is being placed, and, by manipulating the end of the insertion cord, directly affect the orientation of the distal endotracheal tube end, and thereby guide the endotracheal tube through the vocal cords .
  • the endoscopic stylet system of the present invention (1) facilitates simultaneous advancement of the terminal end of an endotracheal tube and of a fiberscopic instrument for visualization of such advancement; (2) permits independent use by a single practitioner by eliminating unnecessary system bulk and fiberscope insertion cord length; (3) substantially reduces likelihood of esophageal intubations and of Murphy's eye entanglement complications; (4) affords its users remote controllability of the terminal segments of the endotracheal tube for ease of maneuvering through action of the associated, remotely controllable segment of the fiberscopic stylet; (5) affords greatly enhanced directional control of the distal portions of the fiberscope; (6) facilitates the negotiation of anatomical features which would otherwise tend to divert the fiberscope in an undesirable direction, or interfere with the 10 endotracheal tube's following of the fiberscope; and
  • Applicant's present invention provides an intubation system 12 which is based on newly designed fiberscope design.
  • the endoscopic stylet of the present invention is designed to serve, not only as the means for transmitting a visual image of the anatomical surfaces of the areas through and to which its distal tip passes during an intubation procedure, but to serve as a semi-rigid stylet which may be formed into, and hold, a shape for conforming generally to the contour of the pathway past which the instrument must pass during the procedure.
  • this semi- rigidity characteristic of the "endoscopic stylet" of the present invention serves the functions of: (1) a stylet for diverting anatomical features, such as the tongue which might (even with the help of a laryngoscope) otherwise obstruct the intubation procedure; and (2) a guide structure for an endotracheal tube which helps prevent a diversion of the endotracheal tube from the course defined by the endoscopic stylet into the trachea, even as against diversionary forces applied by unfavorable upper airway anatomy (such as a posteriorly displaced epiglottis due to lymphoid tissue) , or by soft tissue edema, tumors, or unusually pronounced fatty deposits .
  • a stylet for diverting anatomical features such as the tongue which might (even with the help of a laryngoscope) otherwise obstruct the intubation procedure
  • a guide structure for an endotracheal tube which helps prevent a diversion of the endotracheal tube from the course defined by
  • the features designed into the endoscopic stylet of the present invention were selected specifically for their utility in performing intubation procedures . Absent from the endoscopic stylet are features which have no utility for intubations, and, in fact, may hinder the procedure. Such features include excessive insertion cord length, the one or more working channels, integral suction and irrigation systems, cauterizing tips, etc. which are found in 13 many non- intubation specific fiberscopic instruments.
  • the cross sectional size of the insertion cord of the present endoscopic stylet may, for example, be smaller for accommodating even the smallest endotracheal tubes with which the instrument might be used.
  • the present instrument is a more cost effective choice for intubation procedures than instruments of old design.
  • the endoscopic stylet is provided with a remotely deflectable tip portion.
  • the semi-rigid proximal and middle portions of the insertion cord of the endoscopic stylet greatly facilitate maneuvering the distal tip, past the anatomy of the mouth and throat, into position near the vocal cords. Once in this position, the user actuates the deflectable tip to orient it for easy passage through the vocal cords and into the trachea.
  • the endotracheal tube of the present system is intended to be loaded on the endoscopic stylet during the entirety of the insertion phase of an intubation procedure, and 14 the terminal end of the endotracheal tube is substantially coextensive with that of the endoscopic stylet, deflecting the tip portion of the endoscopic stylet effects a like deflection of the distal portion of the endotracheal tube.
  • the endoscopic stylet and the associated endotracheal tube as a single unit become highly maneuverable by one practitioner using the right hand, while the left hand is maintaining the best possible exposure by placing the laryngoscope in the standard position.
  • the hand motions involved are at least very similar to those already known and employed by most practitioners performing standard endotracheal intubations, aided only by a stylet that puts the operator's eye at the distal end of the endotracheal tube, and gives the operator the ability to flex and rotate the endotracheal tube tip.
  • the endoscopic stylet is configured to correspond to the length of endotracheal tubes with which the instrument will be used, thereby eliminating such excess insertion cord length as would prevent the effective single-handed use of the instrument if it shared length-wise dimensions of typical fiberscopes of the prior art.
  • the handle member which includes the eye piece for viewing images transmitted from the distal tip of the endoscopic stylet and thumb controls for manipulating the divertable distal portion of endoscopic stylet, is compact and situated immediately proximal to the position of a loaded endotracheal tube.
  • the practitioner need only use the right hand to manipulate the endoscopic stylet, leaving the left hand to maintain exposure with the laryngoscope. This obviates the need for a second 15 practitioner.
  • the real-time visual verification of the endoscopic stylet which necessarily carries with it the distal portion of the endotracheal tube as it passes through the vocal cords and into the trachea, insures a proper endotracheal tube placement in every instance.
  • Fig 1. is a perspective view of the intubation system of the present invention.
  • Fig 2. is a cross sectional view of the insertion cord of the endoscopic stylet shown in Fig 1. along Line A - A.
  • Fig 3. is a cross sectional view of the insertion cord of the endoscopic stylet shown in Fig 1. along Line B - B. 16
  • System 10 includes an endoscopic stylet 12 on which is fitted an endotracheal tube 14 when system 10 is configured for use.
  • Endoscopic stylet 12 includes an insertion cord 16 which is of a length such that the distal insertion cord tip 18 extends no further than the distal endotracheal tube tip 20 of the endotracheal tube 14 when fitted on the insertion cord 16.
  • This correlation between the lengths of the endotracheal tube 14 and insertion cord 16 effectively prevents accidental passage of the distal insertion cord tip 18 through the Murphy's eye 22 of the endotracheal tube 14.
  • a terminal segment 24 of the insertion cord 16 of the endoscopic stylet 12 is remotely deflectable using thumb controls 34 which are positioned adjacent to the handle/eye piece 26.
  • Remotely deflectable fiberscope tips and the component mechanisms thereof are known in the art and need not be discussed here for enabling disclosure purposes (see U.S. Patent No. 3572325 issued to Bazell) .
  • the combination of the deflectable tip feature and the other characteristics of the present system (the shorter insertion cord 16, for example) and the associated methodology afford benefits which are not readily apparent to the casual observer.
  • any deflection of the distal insertion cord tip 18 should, and, in the case of 17 the present system, will, effect a similar deflection of the corresponding portion of the endotracheal tube 14.
  • a user is able literally to maneuver the distal portions of the endotracheal tube 14 through use of the thumb controls 34 on handle/eye piece 26. This is in contrast to devices of the prior art .
  • the handle/eye piece 26 of the endoscopic stylet 12 is situated at the proximal end 28 of the insertion cord 16 which closely corresponds to the proximal end 32 of the endotracheal tube 14.
  • the handle/eye piece 26 of the present system 10 is incorporated into a much more compact unit than comparable structures in conventional fiberscopes -- this due to the 18 relative simplicity of endoscopic stylet 12 of the intubation system 10 as will be explained hereafter.
  • the compact structure of the endoscopic stylet 12 greatly facilitates handling and fine control of the system 10 during intubation.
  • Existing units have a great excess of fiberscope insertion cord length and can be unwieldy by most accounts and require two handed operation.
  • the endoscopic stylet of the present invention may be confidently manipulated with a single hand (the right) , and the terminal segment 24 can be controlled using thumb controls 34.
  • FIG. 1 cross sectional views of the insertion cord 16 of the endoscopic stylet 12 at the two indicated sites shows a relatively simple structure.
  • Rigidity member 36 is, in the preferred embodiment, a yieldable, shape-retaining metallic rod which endows the insertion cord 16, and, therefore, the loaded endotracheal tube 14, with the capacity for retaining curvature formed by its user prior to insertion during an intubation in order to conform to the contour of the path which it must traverse during an intubation.
  • the rigidity member 36 extends, in the preferred embodiment, from approximately the proximal end of the insertion cord 16 to a point proximal to the distal insertion cord tip 18, not inclusive of the remotely deflectable terminal segment 24.
  • the result is an insertion cord 16 and endotracheal tube 14, the majority of the length of 19 which (the "semi-rigid segment") holds a desired shape for diverting anatomical features, such as the tongue, which could otherwise impede the intubation procedure.
  • Light guide cables 38, fiberoptic bundle 40, and control wires 42 and 44 are a conventional feature for fiberscopes, and in this case carries light from a light source (not depicted in the drawings) in or near handle/eye piece 26 to the distal tip 46 of the endoscopic stylet 12 for providing light in the area to which the insertion cord 16 is extended during an intubation procedure.
  • Control wires 42 and 44 are connected between thumb controls 34 in the handle/eye piece 26 and the deflection mechanisms in the terminal segment 24 of the insertion cord 16 generally according to conventional design for such mechanisms.
  • the fiberoptic bundle 40 is the group of fiberoptic fibers which carry images from the distal tip 46 of the insertion cord 16 to the optics of handle/eye piece 26.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Endoscopes (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)

Abstract

L'invention concerne un système de tubage (10) fondé sur un fibroscope (12) d'une conception nouvelle et spéciale pour répondre aux exigences toutes particulières de l'intubation. Ce fibroscope (12) possède un cordon d'insertion (16) en grande partie semi-rigide qui permet à un utilisateur de préformer le stylet endoscopique (12) en vue de suivre les contours prévus du conduit aérien menant à la trachée, et pour s'assurer qu'il guide de manière fiable la sonde trachéale associée (14) jusqu'à la position trachéale souhaitée.
PCT/US1998/026399 1998-03-15 1998-12-11 Systeme de tubage WO1999047038A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU18196/99A AU1819699A (en) 1998-03-15 1998-12-11 Intubation system
CA002289614A CA2289614C (fr) 1998-03-15 1998-12-11 Systeme de tubage
US09/423,820 US6432042B1 (en) 1998-12-11 1998-12-11 Intubation system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3954398A 1998-03-15 1998-03-15
US09/039,543 1998-03-15

Publications (1)

Publication Number Publication Date
WO1999047038A1 true WO1999047038A1 (fr) 1999-09-23

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ID=21906036

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/026399 WO1999047038A1 (fr) 1998-03-15 1998-12-11 Systeme de tubage

Country Status (3)

Country Link
AU (1) AU1819699A (fr)
CA (1) CA2289614C (fr)
WO (1) WO1999047038A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001078582A1 (fr) * 2000-04-18 2001-10-25 Page 65, S.L. Laryngoscope optique lumineux
ES2160551A1 (es) * 2000-04-18 2001-11-01 Acha Gandarias Pedro Laringoscopio optico-luminoso simplificado.
EP1494743A1 (fr) * 2002-03-20 2005-01-12 Board Of Regents, The University Of Texas System Ensemble a voies aeriennes
EP2659928A4 (fr) * 2010-12-29 2015-07-08 Zhiyang Chen Tube trachéal à embouchure plate et une ouverture latérale et âme de guidage
JP2016527024A (ja) * 2013-07-22 2016-09-08 ダブリューエム・アンド・ディージー，インク 医療機器、及び当該医療機器の使用方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742819A (en) * 1987-03-23 1988-05-10 George Gordon P Intubating scope with camera and screen
US5327881A (en) * 1993-02-26 1994-07-12 Beth Israel Hospital Association Fiberoptic intubating stylet
US5676635A (en) * 1995-08-30 1997-10-14 Levin; Bruce Instrument for insertion of an endotracheal tube

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742819A (en) * 1987-03-23 1988-05-10 George Gordon P Intubating scope with camera and screen
US5327881A (en) * 1993-02-26 1994-07-12 Beth Israel Hospital Association Fiberoptic intubating stylet
US5676635A (en) * 1995-08-30 1997-10-14 Levin; Bruce Instrument for insertion of an endotracheal tube

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001078582A1 (fr) * 2000-04-18 2001-10-25 Page 65, S.L. Laryngoscope optique lumineux
ES2160551A1 (es) * 2000-04-18 2001-11-01 Acha Gandarias Pedro Laringoscopio optico-luminoso simplificado.
US6843769B1 (en) 2000-04-18 2005-01-18 Page 65, S.L. Optical luminous laryngoscope
AU2000276658B2 (en) * 2000-04-18 2005-11-17 Prodol Meditec S.A. Optical luminous laryngoscope
EP1494743A1 (fr) * 2002-03-20 2005-01-12 Board Of Regents, The University Of Texas System Ensemble a voies aeriennes
EP1494743A4 (fr) * 2002-03-20 2006-06-07 Univ Texas Ensemble a voies aeriennes
EP2659928A4 (fr) * 2010-12-29 2015-07-08 Zhiyang Chen Tube trachéal à embouchure plate et une ouverture latérale et âme de guidage
JP2016527024A (ja) * 2013-07-22 2016-09-08 ダブリューエム・アンド・ディージー，インク 医療機器、及び当該医療機器の使用方法

Also Published As

Publication number Publication date
CA2289614A1 (fr) 1999-09-23
AU1819699A (en) 1999-10-11
CA2289614C (fr) 2005-07-05

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