WO1999038976A3 - Human growth factor homologs - Google Patents

Human growth factor homologs Download PDF

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Publication number
WO1999038976A3
WO1999038976A3 PCT/US1999/000654 US9900654W WO9938976A3 WO 1999038976 A3 WO1999038976 A3 WO 1999038976A3 US 9900654 W US9900654 W US 9900654W WO 9938976 A3 WO9938976 A3 WO 9938976A3
Authority
WO
WIPO (PCT)
Prior art keywords
growth factor
human growth
hgfh
factor homologs
provides
Prior art date
Application number
PCT/US1999/000654
Other languages
French (fr)
Other versions
WO1999038976A2 (en
Inventor
Jennifer L Hillman
Preeti Lal
Neil C Corley
Mariah Baughn
Karl J Guegler
Y Tom Tang
Original Assignee
Incyte Pharma Inc
Jennifer L Hillman
Preeti Lal
Neil C Corley
Mariah Baughn
Karl J Guegler
Y Tom Tang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Jennifer L Hillman, Preeti Lal, Neil C Corley, Mariah Baughn, Karl J Guegler, Y Tom Tang filed Critical Incyte Pharma Inc
Priority to AU22235/99A priority Critical patent/AU2223599A/en
Priority to CA002317812A priority patent/CA2317812A1/en
Priority to JP2000529435A priority patent/JP2002501747A/en
Priority to EP99902197A priority patent/EP1051488A2/en
Publication of WO1999038976A2 publication Critical patent/WO1999038976A2/en
Publication of WO1999038976A3 publication Critical patent/WO1999038976A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides human growth factor homologs (HGFH) and polynucleotides which identify and encode HGFH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HGFH.
PCT/US1999/000654 1998-01-29 1999-01-12 Human growth factor homologs WO1999038976A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU22235/99A AU2223599A (en) 1998-01-29 1999-01-12 Human growth factor homologs
CA002317812A CA2317812A1 (en) 1998-01-29 1999-01-12 Human growth factor homologs
JP2000529435A JP2002501747A (en) 1998-01-29 1999-01-12 Human growth factor homolog
EP99902197A EP1051488A2 (en) 1998-01-29 1999-01-12 Human growth factor homologs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1541298A 1998-01-29 1998-01-29
US09/015,412 1998-01-29

Publications (2)

Publication Number Publication Date
WO1999038976A2 WO1999038976A2 (en) 1999-08-05
WO1999038976A3 true WO1999038976A3 (en) 1999-11-25

Family

ID=21771253

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/000654 WO1999038976A2 (en) 1998-01-29 1999-01-12 Human growth factor homologs

Country Status (5)

Country Link
EP (1) EP1051488A2 (en)
JP (1) JP2002501747A (en)
AU (1) AU2223599A (en)
CA (1) CA2317812A1 (en)
WO (1) WO1999038976A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6893844B1 (en) * 1998-09-22 2005-05-17 Long Yu DNA encoding a new human hepatoma derived growth factor and producing method thereof
WO2000037492A2 (en) * 1998-12-22 2000-06-29 Eli Lilly And Company Human hepatoma-derived growth factor homologous (huhdgfh) ____
AU6871900A (en) 1999-09-06 2001-04-10 Chugai Seiyaku Kabushiki Kaisha Tsg-like gene
EP1224286A2 (en) 1999-10-26 2002-07-24 Lee A. Bulla, Jr. Gene mining system and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015966A1 (en) * 1993-01-12 1994-07-21 Johns Hopkins University School Of Medicine Growth differentiation factor-9
WO1996039485A1 (en) * 1995-06-05 1996-12-12 Human Genome Sciences, Inc. Human hepatoma-derived growth factor-2
WO1997034998A1 (en) * 1996-03-20 1997-09-25 Human Genome Sciences, Inc. Human cytokine polypeptide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015966A1 (en) * 1993-01-12 1994-07-21 Johns Hopkins University School Of Medicine Growth differentiation factor-9
WO1996039485A1 (en) * 1995-06-05 1996-12-12 Human Genome Sciences, Inc. Human hepatoma-derived growth factor-2
WO1997034998A1 (en) * 1996-03-20 1997-09-25 Human Genome Sciences, Inc. Human cytokine polypeptide

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL - EMEST1 30 July 1997 (1997-07-30), STRAUSBERG, R.: "no76e01.s1 NCI_CGAP_AA1 homo sapiens cDNA clone IMAGE:1112760 similar to SW:GDF9_MOUSE Q07105 GROWTH/DIFFERENTIATION FACTOR 9 PRECURSOR.", XP002105030 *
DATABASE EMBL - EMHUM1 6 April 1998 (1998-04-06), KIMMERLY, W. ET AL.: "Homo spaiens chromosome 5, P1 clone 1076B9 (LBNL H14), complete sequence.", XP002105031 *
MCPHERRON A C ET AL: "GDF-3 AND GDF-9: TWO NEW MEMBERS OF THE TRANSFORMING GROWTH FACTOR -B SUPERFAMILY CONTAINING A NOVEL PATTERN OF CYSTEINES", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 268, no. 5, 15 February 1993 (1993-02-15), pages 3444 - 3449, XP000348932 *

Also Published As

Publication number Publication date
CA2317812A1 (en) 1999-07-05
JP2002501747A (en) 2002-01-22
AU2223599A (en) 1999-08-16
EP1051488A2 (en) 2000-11-15
WO1999038976A2 (en) 1999-08-05

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