WO1999035255A8 - Compositions and methods for regulated secretion from neuroendocrine cell lines - Google Patents
Compositions and methods for regulated secretion from neuroendocrine cell linesInfo
- Publication number
- WO1999035255A8 WO1999035255A8 PCT/US1999/000631 US9900631W WO9935255A8 WO 1999035255 A8 WO1999035255 A8 WO 1999035255A8 US 9900631 W US9900631 W US 9900631W WO 9935255 A8 WO9935255 A8 WO 9935255A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- compositions
- cells
- cell lines
- present
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/507—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/22—Zinc; Zn chelators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/40—Nucleotides, nucleosides, bases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/46—Amines, e.g. putrescine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU24551/99A AU2455199A (en) | 1998-01-12 | 1999-01-11 | Compositions and methods for regulated secretion from neuroendocrine cell lines |
CA 2318376 CA2318376A1 (en) | 1998-01-12 | 1999-01-11 | Compositions and methods for regulated secretion from neuroendocrine cell lines |
EP99904073A EP1045898A2 (en) | 1998-01-12 | 1999-01-11 | Compositions and methods for regulated secretion from neuroendocrine cell lines |
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7119398P | 1998-01-12 | 1998-01-12 | |
US7255698P | 1998-01-12 | 1998-01-12 | |
US7120998P | 1998-01-12 | 1998-01-12 | |
US60/072,556 | 1998-01-12 | ||
US60/071,193 | 1998-01-12 | ||
US60/071,209 | 1998-01-12 | ||
US8784898P | 1998-06-03 | 1998-06-03 | |
US8782198P | 1998-06-03 | 1998-06-03 | |
US60/087,821 | 1998-06-03 | ||
US60/087,848 | 1998-06-03 |
Publications (4)
Publication Number | Publication Date |
---|---|
WO1999035255A2 WO1999035255A2 (en) | 1999-07-15 |
WO1999035255A8 true WO1999035255A8 (en) | 1999-09-10 |
WO1999035255A3 WO1999035255A3 (en) | 1999-10-28 |
WO1999035255A9 WO1999035255A9 (en) | 2001-05-31 |
Family
ID=27535873
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/000631 WO1999035255A2 (en) | 1998-01-12 | 1999-01-11 | Compositions and methods for regulated secretion from neuroendocrine cell lines |
PCT/US1999/000551 WO1999035495A2 (en) | 1998-01-12 | 1999-01-11 | Identification of substances that modify cellular secretory function |
PCT/US1999/000633 WO1999035242A1 (en) | 1998-01-12 | 1999-01-11 | Media for neuroendocrine cells |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/000551 WO1999035495A2 (en) | 1998-01-12 | 1999-01-11 | Identification of substances that modify cellular secretory function |
PCT/US1999/000633 WO1999035242A1 (en) | 1998-01-12 | 1999-01-11 | Media for neuroendocrine cells |
Country Status (4)
Country | Link |
---|---|
EP (2) | EP1045898A2 (en) |
AU (3) | AU2112199A (en) |
CA (2) | CA2318376A1 (en) |
WO (3) | WO1999035255A2 (en) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001068136A1 (en) * | 2000-03-17 | 2001-09-20 | Ajinomoto Co., Inc. | Drugs for complications of diabetes and neuropathy and utilization thereof |
US7501231B2 (en) | 2001-03-23 | 2009-03-10 | University Of Ottawa | Methods and compositions for cryopreservation of dissociated primary animal cells |
US7166463B2 (en) | 2001-11-16 | 2007-01-23 | The Regents Of The University Of Colorado | Nucleic acids encoding modified olfactory cyclic nucleotide gated ion channels |
MX2007015949A (en) | 2005-06-17 | 2008-03-07 | Vital Health Sciences Pty Ltd | A carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof. |
ES2336575T3 (en) | 2005-09-22 | 2010-04-14 | Biocompatibles Uk Limited | GLP-1 FUSION POLYPEPTIDES (PEPTIDE-1 SIMILAR TO GLUCAGON) WITH INCREASED RESISTANCE TO PEPTIDASE. |
EP2522717B1 (en) | 2006-01-04 | 2014-04-02 | Baxter International Inc | Oligopeptide-free cell culture media |
ATE444741T1 (en) | 2006-05-10 | 2009-10-15 | Biocompatibles Uk Ltd | Spherical microcapsules containing GLP-1 peptides, their production and their use |
KR101495549B1 (en) | 2006-07-13 | 2015-02-25 | 와이어쓰 엘엘씨 | Production of glycoproteins |
US20100173409A1 (en) | 2007-05-01 | 2010-07-08 | Vitrolife Sweden Ab | Culture media for developmental cells containing elevated concentrations of lipoic acid |
WO2009046860A2 (en) * | 2007-09-11 | 2009-04-16 | Mondobiotech Laboratories Ag | Use of dago as a therapeutic agent |
EP2163243A1 (en) * | 2008-09-12 | 2010-03-17 | Biocompatibles UK Limited | Treatment of acute myocardial infarction (AMI) using encapsulated cells encoding and secreting GLP-1 peptides or analogs thereof |
SG178358A1 (en) * | 2009-08-11 | 2012-03-29 | Genentech Inc | Production of proteins in glutamine-free cell culture media |
AU2011213557B2 (en) | 2010-02-05 | 2015-05-07 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
NZ601528A (en) * | 2010-02-05 | 2015-04-24 | Phosphagenics Ltd | A low solvent carrier composition for delivery of biologically active compounds |
RU2553350C2 (en) | 2010-03-30 | 2015-06-10 | Фосфейдженикс Лимитед | Transdermal plaster |
US9540607B2 (en) | 2011-02-22 | 2017-01-10 | Cytonet, Llc | Fill system for providing uniform concentrations and volumes and methods thereof |
WO2012122586A1 (en) | 2011-03-15 | 2012-09-20 | Phosphagenics Limited | New composition |
US8945876B2 (en) | 2011-11-23 | 2015-02-03 | University Of Hawaii | Auto-processing domains for polypeptide expression |
US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
AR095196A1 (en) | 2013-03-15 | 2015-09-30 | Regeneron Pharma | SERUM FREE CELL CULTIVATION MEDIA |
WO2015066631A2 (en) * | 2013-11-01 | 2015-05-07 | University Of Notre Dame Du Lac | Cell culture medium and bioprocess optimization |
WO2015077523A1 (en) * | 2013-11-22 | 2015-05-28 | Le Centre Nationale De La Recherche Scientifique (Cnrs) | Assay-ready frozen cell and method for minimizing variability in the performance thereof |
US10918110B2 (en) | 2015-07-08 | 2021-02-16 | Corning Incorporated | Antimicrobial phase-separating glass and glass ceramic articles and laminates |
TWI797060B (en) | 2015-08-04 | 2023-04-01 | 美商再生元醫藥公司 | Taurine supplemented cell culture medium and methods of use |
EP3383371B1 (en) | 2015-12-09 | 2024-05-01 | Avecho Biotechnology Limited | Pharmaceutical formulation |
JP7198754B2 (en) | 2016-12-21 | 2023-01-04 | アベーチョ バイオテクノロジー リミテッド | Method |
KR102569522B1 (en) * | 2017-11-24 | 2023-08-24 | 주식회사 차바이오랩 | Composition for cryopreservation of cell and method for cryopreservation of cell using the same |
WO2020206187A1 (en) * | 2019-04-02 | 2020-10-08 | Centagen, Inc | Engineered system of stem cell rejuvenation to treat aging and disease |
CN114868736B (en) * | 2022-03-08 | 2022-12-09 | 四川中科奥格生物科技有限公司 | Islet cell stabilizing solution and preparation method and application thereof |
CN114561337B (en) * | 2022-03-09 | 2023-10-03 | 广州源井生物科技有限公司 | Monoclonal enhancement culture medium and method for improving clone formation rate of HepG2 cells |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5180662A (en) * | 1988-01-05 | 1993-01-19 | The United States Of America As Represented By The Department Of Health And Human Services | Cytotoxic T lymphocyte activation assay |
US5427940A (en) * | 1991-06-03 | 1995-06-27 | Board Of Regents, The University Of Texas System | Engineered cells producing insulin in response to glucose |
AU650045B2 (en) * | 1990-09-12 | 1994-06-09 | Lifecell Corporation | Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions |
WO1993002183A1 (en) * | 1991-07-18 | 1993-02-04 | Fuji Yakuhin Kogyo Kabushiki Kaisha | Serum-free tissue culture medium containing tissue inhibitor of metalloproteinase and method for cell growth |
GB9125052D0 (en) * | 1991-11-26 | 1992-01-22 | Isis Innovation | Culture of bone cells |
FR2726005B1 (en) * | 1994-10-10 | 1997-01-03 | Adim | IMMORTALIZED LINES OF CEREBRAL ENDOTHELIAL CELLS AND THEIR APPLICATIONS FOR THE TREATMENT OF DIFFERENT NEUROLOGICAL OR PSYCHIATRIC PRIMARY AND SECONDARY DISORDERS OR DISEASES |
WO1997026321A2 (en) * | 1996-01-19 | 1997-07-24 | Board Of Regents, The University Of Texas System | Recombinant expression of proteins from secretory cell lines |
-
1999
- 1999-01-11 WO PCT/US1999/000631 patent/WO1999035255A2/en not_active Application Discontinuation
- 1999-01-11 EP EP99904073A patent/EP1045898A2/en not_active Withdrawn
- 1999-01-11 WO PCT/US1999/000551 patent/WO1999035495A2/en not_active Application Discontinuation
- 1999-01-11 CA CA 2318376 patent/CA2318376A1/en not_active Abandoned
- 1999-01-11 AU AU21121/99A patent/AU2112199A/en not_active Abandoned
- 1999-01-11 AU AU21131/99A patent/AU2113199A/en not_active Abandoned
- 1999-01-11 CA CA 2318379 patent/CA2318379A1/en not_active Abandoned
- 1999-01-11 WO PCT/US1999/000633 patent/WO1999035242A1/en active Application Filing
- 1999-01-11 EP EP99901421A patent/EP1047938A2/en not_active Withdrawn
- 1999-01-11 AU AU24551/99A patent/AU2455199A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1999035255A2 (en) | 1999-07-15 |
CA2318376A1 (en) | 1999-07-15 |
EP1047938A2 (en) | 2000-11-02 |
WO1999035495A3 (en) | 1999-11-25 |
WO1999035242A1 (en) | 1999-07-15 |
AU2113199A (en) | 1999-07-26 |
WO1999035255A9 (en) | 2001-05-31 |
WO1999035255A3 (en) | 1999-10-28 |
WO1999035495A2 (en) | 1999-07-15 |
EP1045898A2 (en) | 2000-10-25 |
AU2455199A (en) | 1999-07-26 |
AU2112199A (en) | 1999-07-26 |
WO1999035242A9 (en) | 1999-09-30 |
CA2318379A1 (en) | 1999-07-15 |
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