WO1999024574A3 - Homologues vegetaux de pad1 et de crm1 de levure et de jab1 humaine: regulateurs de l'activite du facteur de transcription de type ap-1 - Google Patents

Homologues vegetaux de pad1 et de crm1 de levure et de jab1 humaine: regulateurs de l'activite du facteur de transcription de type ap-1 Download PDF

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Publication number
WO1999024574A3
WO1999024574A3 PCT/US1998/023487 US9823487W WO9924574A3 WO 1999024574 A3 WO1999024574 A3 WO 1999024574A3 US 9823487 W US9823487 W US 9823487W WO 9924574 A3 WO9924574 A3 WO 9924574A3
Authority
WO
WIPO (PCT)
Prior art keywords
yeast
transcription factor
factor activity
jab1
crm1
Prior art date
Application number
PCT/US1998/023487
Other languages
English (en)
Other versions
WO1999024574A2 (fr
Inventor
Stephen M Allen
Shawn L Anderson
William D Hitz
Anthony J Kinney
Guo-Hua Miao
Michele Morgante
Joan T Odell
Hajime Sakai
Original Assignee
Du Pont
Stephen M Allen
Shawn L Anderson
William D Hitz
Anthony J Kinney
Miao Guo Hua
Michele Morgante
Joan T Odell
Hajime Sakai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Stephen M Allen, Shawn L Anderson, William D Hitz, Anthony J Kinney, Miao Guo Hua, Michele Morgante, Joan T Odell, Hajime Sakai filed Critical Du Pont
Priority to BR9815305-6A priority Critical patent/BR9815305A/pt
Priority to AU13804/99A priority patent/AU1380499A/en
Priority to EP98957575A priority patent/EP1034274A2/fr
Publication of WO1999024574A2 publication Critical patent/WO1999024574A2/fr
Publication of WO1999024574A3 publication Critical patent/WO1999024574A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne un fragment d'acide nucléique codant pour une protéine impliquée dans la régulation de l'activité du facteur de transcription AP-1. Elle concerne également la construction d'un gène chimère codant pour tout ou partie de ladite protéine, en orientation sens ou antisens, dont l'expression modifie le niveau de la protéine impliquée dans l'activité du facteur de transcription AP-1 dans une cellule hôte transformée.
PCT/US1998/023487 1997-11-07 1998-11-04 Homologues vegetaux de pad1 et de crm1 de levure et de jab1 humaine: regulateurs de l'activite du facteur de transcription de type ap-1 WO1999024574A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
BR9815305-6A BR9815305A (pt) 1997-11-07 1998-11-04 Fragmento de acido nucléico, gene quimérico, célula hospedeira, polipeptidio pad1, polipeptìdio jab1, método para a alteração do nìvel de expressão de uma proteìna, método para obtenção de um fragmento de ácido nucléico e produto
AU13804/99A AU1380499A (en) 1997-11-07 1998-11-04 Plant homologs of yeast pad1, yeast crm1, and human jab1: regulators of ap-1 type transcription factor activity
EP98957575A EP1034274A2 (fr) 1997-11-07 1998-11-04 Homologues vegetaux de pad1 et de crm1 de levure et de jab1 humaine: regulateurs de l'activite du facteur de transcription de type ap-1

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6491497P 1997-11-07 1997-11-07
US60/064,914 1997-11-07

Publications (2)

Publication Number Publication Date
WO1999024574A2 WO1999024574A2 (fr) 1999-05-20
WO1999024574A3 true WO1999024574A3 (fr) 1999-12-09

Family

ID=22059097

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/023487 WO1999024574A2 (fr) 1997-11-07 1998-11-04 Homologues vegetaux de pad1 et de crm1 de levure et de jab1 humaine: regulateurs de l'activite du facteur de transcription de type ap-1

Country Status (4)

Country Link
EP (1) EP1034274A2 (fr)
AU (1) AU1380499A (fr)
BR (1) BR9815305A (fr)
WO (1) WO1999024574A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7479555B2 (en) 1999-07-21 2009-01-20 Ceres, Inc. Polynucleotides having a nucleotide sequence that encodes a polypeptide having MOV34 family activity
CA2300328A1 (fr) 1999-09-14 2001-03-14 Cardiogene Gentherap. Systeme Ag Modulation de la transcription des genes dans des cellules vasculaires
DE29916160U1 (de) 1999-09-14 2000-03-09 Cardiogene Gentherapeutische Systeme AG, 40699 Erkrath Modulation der Transkription von Genen in vaskulären Zellen
DE19957065B4 (de) * 1999-11-26 2005-01-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Screening-Verfahren für Arzneistoffe
FR2806095A1 (fr) * 2000-03-10 2001-09-14 Gentech Sequences polynucleotidiques purifiees de plantes et de levure codant pour des proteines qui interagissent avec les produits du genome des geminivirus
KR100602146B1 (ko) 2004-08-31 2006-07-19 학교법인 성균관대학 Ｊａｂ1을 포함하는 바이러스 감염 질환 치료 조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005249A2 (fr) * 1995-07-31 1997-02-13 The Government Of The United States Of America, Represented By The Secretary, Department Of Healt H And Human Services Prolongement d'une surface d'interaction proteine-proteine afin d'inactiver le fonctionnement d'une proteine cellulaire

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005249A2 (fr) * 1995-07-31 1997-02-13 The Government Of The United States Of America, Represented By The Secretary, Department Of Healt H And Human Services Prolongement d'une surface d'interaction proteine-proteine afin d'inactiver le fonctionnement d'une proteine cellulaire

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
D.A. CHAMOVITZ ET AL.,: "The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch", CELL, vol. 86, no. 1, 1996, pages 115 - 121, XP002103873 *
LUPAS A ET AL: "A repetitive sequence in subunits of the 26S proteasome and 20S cyclosome (anaphase-promoting complex)", TIBS TRENDS IN BIOCHEMICAL SCIENCES, vol. 22, no. 6, 1 June 1997 (1997-06-01), pages 195-196, XP004074678 *
LUPAS A ET AL: "Self-compartmentalizing proteases", TIBS TRENDS IN BIOCHEMICAL SCIENCES, vol. 22, no. 10, 1 October 1997 (1997-10-01), pages 399-404, XP004092001 *
M. PENNEY ET AL.,: "The pad1+ gene encodes a subunit of the 26 S proteasome in fission yeast", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 37, 11 September 1998 (1998-09-11), pages 23938 - 23945, XP002103877 *
M. SHIMANUKI ET AL.,: "A novel essential fission yeast gene pad1+ positively regulates pap1+-dependent transcription and is implicated in the maintenance of chromosome structure", JOURNAL OF CELL SCIENCE, vol. 108, 1995, pages 569 - 579, XP002103875 *
P. HILSON ET AL.,: "Fos and Jun oncogenes transactivate chimeric or native promoters containing AP1-GCN4 binding sites in plant cells", PLANT CELL, vol. 2, no. 7, 1990, pages 651 - 658, XP002103874 *
SPATARO ET AL.,: "Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26S proteasome subunit", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, 1997, pages 30470 - 30475, XP002103876 *
W. NING AND X-W DENG: "COP9: A new genetic locus involved in light-regulated development and gene expression in arabidopsis", PLANT CELL, vol. 4, no. 12, 1992, pages 1507 - 1518, XP002103872 *
X-W. DENG ET AL.,: "COP1, an Arabidopsis regulatory gene, encodes a protein with both a zinc-binding motif and a G-beta homologous domain", CELL, vol. 71, no. 5, 1992, pages 791 - 801, XP002103871 *

Also Published As

Publication number Publication date
AU1380499A (en) 1999-05-31
EP1034274A2 (fr) 2000-09-13
BR9815305A (pt) 2001-02-13
WO1999024574A2 (fr) 1999-05-20

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