WO1999019481A3 - Mammalian genes involved in viral infection and tumor suppression - Google Patents
Mammalian genes involved in viral infection and tumor suppression Download PDFInfo
- Publication number
- WO1999019481A3 WO1999019481A3 PCT/US1998/021276 US9821276W WO9919481A3 WO 1999019481 A3 WO1999019481 A3 WO 1999019481A3 US 9821276 W US9821276 W US 9821276W WO 9919481 A3 WO9919481 A3 WO 9919481A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- viral infection
- genes involved
- tumor suppression
- mammalian genes
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/60—Vectors containing traps for, e.g. exons, promoters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU96041/98A AU9604198A (en) | 1997-10-10 | 1998-10-08 | Mammalian genes involved in viral infection and tumor suppression |
EP98949800A EP1021536A2 (en) | 1997-10-10 | 1998-10-08 | Mammalian genes involved in viral infection and tumor suppression |
JP2000516033A JP2001520012A (en) | 1997-10-10 | 1998-10-08 | Mammalian genes involved in viral infection and tumor suppression |
CA2305312A CA2305312C (en) | 1997-10-10 | 1998-10-08 | Mammalian genes involved in viral infection and tumor suppression |
US09/509,712 US6777177B1 (en) | 1997-10-10 | 1998-10-08 | Mammalian genes involved in viral infection and tumor suppression |
US10/877,807 US20050112553A1 (en) | 1997-10-10 | 2004-06-25 | Mammalian genes involved in viral infection and tumor suppression |
US11/033,764 US20050244817A1 (en) | 1996-04-15 | 2005-01-12 | Mammalian genes involved in viral infection and tumor suppression |
US12/210,869 US20090092594A1 (en) | 1996-04-15 | 2008-09-15 | Mammalian genes involved in viral infection and tumor suppression |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6202197P | 1997-10-10 | 1997-10-10 | |
US60/062,021 | 1997-10-10 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/877,807 Continuation US20050112553A1 (en) | 1996-04-15 | 2004-06-25 | Mammalian genes involved in viral infection and tumor suppression |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999019481A2 WO1999019481A2 (en) | 1999-04-22 |
WO1999019481A3 true WO1999019481A3 (en) | 1999-11-04 |
Family
ID=22039706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/021276 WO1999019481A2 (en) | 1996-04-15 | 1998-10-08 | Mammalian genes involved in viral infection and tumor suppression |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1021536A2 (en) |
JP (2) | JP2001520012A (en) |
AU (1) | AU9604198A (en) |
CA (2) | CA2696653A1 (en) |
WO (1) | WO1999019481A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001016323A2 (en) * | 1999-09-01 | 2001-03-08 | Subsidiary N0.3, Inc. | Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes |
JP2002300900A (en) * | 2001-04-05 | 2002-10-15 | National Institute Of Advanced Industrial & Technology | Method for screening tumor-worsening factor and tumor worsening-inhibiting compound |
EP1409736A4 (en) * | 2001-06-29 | 2004-07-21 | Subsidiary N0 3 Inc | Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes |
AU2003234445B2 (en) * | 2002-05-02 | 2009-11-26 | Vanderbilt University | Mammalian genes involved in viral infection and tumor suppression |
EP2339009A1 (en) * | 2009-12-22 | 2011-06-29 | Sandoz Ag | Cold inducible promoter sequences |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990009192A1 (en) * | 1989-02-14 | 1990-08-23 | Massachusetts Institute Of Technology | Inhibiting transformation of cells having elevated purine metabolic enzyme activity |
WO1993009230A1 (en) * | 1991-11-05 | 1993-05-13 | Board Of Regents, The University Of Texas System | Cellular nucleic acid binding protein and uses thereof in regulating gene expression and in the treatment of aids |
US5627058A (en) * | 1990-05-14 | 1997-05-06 | Massachusetts Institute Of Technology | Retrovirus promoter-trap vectors |
WO1997039119A1 (en) * | 1996-04-15 | 1997-10-23 | Vanderbilt University | Mammalian genes involved in viral infection and tumor suppression |
-
1998
- 1998-10-08 CA CA2696653A patent/CA2696653A1/en not_active Abandoned
- 1998-10-08 JP JP2000516033A patent/JP2001520012A/en not_active Withdrawn
- 1998-10-08 EP EP98949800A patent/EP1021536A2/en not_active Withdrawn
- 1998-10-08 AU AU96041/98A patent/AU9604198A/en not_active Abandoned
- 1998-10-08 CA CA2305312A patent/CA2305312C/en not_active Expired - Fee Related
- 1998-10-08 WO PCT/US1998/021276 patent/WO1999019481A2/en active Application Filing
-
2009
- 2009-02-16 JP JP2009033300A patent/JP2009100780A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990009192A1 (en) * | 1989-02-14 | 1990-08-23 | Massachusetts Institute Of Technology | Inhibiting transformation of cells having elevated purine metabolic enzyme activity |
US5627058A (en) * | 1990-05-14 | 1997-05-06 | Massachusetts Institute Of Technology | Retrovirus promoter-trap vectors |
WO1993009230A1 (en) * | 1991-11-05 | 1993-05-13 | Board Of Regents, The University Of Texas System | Cellular nucleic acid binding protein and uses thereof in regulating gene expression and in the treatment of aids |
WO1997039119A1 (en) * | 1996-04-15 | 1997-10-23 | Vanderbilt University | Mammalian genes involved in viral infection and tumor suppression |
Non-Patent Citations (3)
Title |
---|
E. ORGAN ET AL.: "U3 gene-trap retrovirus selection of cellular mutants resistant to lytic reovirus infection", J. INVESTIGATIVE MEDICINE, ISSN: 1081-5589,, vol. 44, no. 3, March 1996 (1996-03-01), pages 320A, XP002090533 * |
EVANS M J ET AL: "Gene trapping and functional genomics", TRENDS IN GENETICS, vol. 13, no. 9, September 1997 (1997-09-01), pages 370-374, XP004086832 * |
SKARNES W C: "THE IDENTIFICATION OF NEW GENES: GENE TRAPPING IN TRANSGENIC MICE", CURRENT OPINION IN BIOTECHNOLOGY, vol. 4, 1 January 1993 (1993-01-01), pages 684 - 689, XP000569473 * |
Also Published As
Publication number | Publication date |
---|---|
EP1021536A2 (en) | 2000-07-26 |
JP2009100780A (en) | 2009-05-14 |
AU9604198A (en) | 1999-05-03 |
JP2001520012A (en) | 2001-10-30 |
CA2696653A1 (en) | 1999-04-22 |
CA2305312A1 (en) | 1999-04-22 |
WO1999019481A2 (en) | 1999-04-22 |
CA2305312C (en) | 2010-03-23 |
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