WO1999008664A1

WO1999008664A1 - Support for patches and patches provided with the support

Info

Publication number: WO1999008664A1
Application number: PCT/JP1998/003614
Authority: WO
Inventors: Shinya Kojima
Original assignee: Chugai Seiyaku Kabushikikaisha
Priority date: 1997-08-13
Filing date: 1998-08-13
Publication date: 1999-02-25
Also published as: AU8648798A; KR20010022758A

Abstract

A support for patches for temporarily imparting rigidity to a substrate by being stuck to a surface opposite to an adherent surface of the substrate of the patch, comprising a tacky surface (3) having a lower viscosity than that of a patch and applied to one of the surfaces of a member (2) having a suitable rigidity and made of a cloth, paper, non-woven fabric, a plastic film, etc, and a cylindrical or bag-like belt portion (4) allowing the insertion of fingers, etc., and disposed on the surface opposite to the tacky surface (3); and patches to which the support has been in advance stuck.

Description

Description Patch support and patch with the support

TECHNICAL FIELD The present invention relates to a support used when applying a patch such as an external anti-inflammatory analgesic to an affected part, and a patch provided with the support. Background art

A patch such as an external anti-inflammatory analgesic is composed of a base material and a plaster provided on one surface of the base, and the plaster or the like has a transdermally applicable medicinal effect such as an anti-inflammatory analgesic. Contains ingredients. Usually, the adhesive surface is coated with a protective film or the like to prevent the adhesive surface provided with the plaster or the like from being stained or dried before use.

Such a patch is used by a patient or a third party after peeling off a protective film or the like from the adhesive surface on which the plaster or the like is provided, and then applying it so that the adhesive surface side adheres to the affected part. In recent years, the mainstream of such patches has been to use a soft and thin base material to reduce the weight of the plaster or the like in order to improve the adhesion to the affected area and to improve the feel after application. I have.

Since such a patch uses a soft base material, a good feel can be obtained even after the patch is applied. Particularly, even when the affected part has irregularities or is a curved part, it is easy to apply and has sufficient adhesion. There are advantages such as being obtainable and not hindering flexion and extension of joints and the like even when affixed to joints and the like.

However, on the other hand, there are disadvantages because the base material is soft and thin.

That is, at the stage of use, when the protective film or the like is peeled off from the above-mentioned adhesive surface, the base material is quickly broken away. Also, especially when the patient attaches it to the affected area by himself, peel off the protective film, etc., and then attach it to the affected area, such as the shoulder, back, or waist, which is difficult to reach. It is inevitable that the agent is difficult to hold and that the adhesive surfaces are easy to stick together. A first object of the present invention is to provide a patch having a soft base material, which can prevent sticking of the adhesive surfaces from each other, and can be easily attached to affected parts such as shoulders, back, and waist. An object of the present invention is to provide an agent support.

A second object of the present invention is to make use of the above-mentioned advantages as a patch having a soft base material, without sticking the adhesive surfaces together, and allowing the patient to apply the patch to affected areas such as shoulders, back, and waist. An object of the present invention is to provide an easy-to-use patch. Disclosure of the invention

In the present invention, in order to achieve the first object, when applying the patch, the support is used to temporarily make the substrate of the patch have rigidity so as to prevent the adhesive surfaces from sticking to each other. I have to.

That is, according to one aspect of the present invention, when a patch having a flexible base material is applied to an affected area, the support is used temporarily to support the base material of the patch. And a support member attached to the non-stick side of the substrate, and a belt provided on the support member, wherein the support member is attached to the substrate when attached to the substrate. It is characterized in that it has a size and rigidity capable of maintaining the flatness of the material, and is attached to the non-sticking side of the substrate by an attaching means having an adhesive force lower than the adhesive force of the adhesive surface of the adhesive patch. A patch support is obtained.

Further, the support member is formed in a sheet shape having substantially the same size as the base material, and the attaching means is provided on one surface of the sheet-like support member, and is based on the adhesive strength of the adhesive surface of the patch. It can be constituted by another adhesive surface having a low viscosity. Further, the belt portion may be formed of a tubular portion or a bag-shaped portion provided on the other surface of the support member and into which a finger of a hand can be inserted.

It is preferable that the other adhesive surface is covered with a release paper for protection.

In addition, the support member is made of cloth such as cotton cloth, regenerated cellulose cloth, chemical fiber cloth, and non-woven cloth, paper such as Japanese paper and craft paper, hard vinyl chloride, polypropylene, and polyethylene. It can be composed of resin, polyester, polyamide, polycarbonate, and their copolymers, plastic films such as vent fans, metal flakes, or laminates thereof.

In addition to the above, in the present invention, in order to achieve the second object, a patch is prepared by previously bonding a support member including the belt portion to a surface of the substrate opposite to the adhesive surface. After the agent is applied, the support member including the belt portion is peeled off from the base material so that only the base material and the medicinal component are used.

That is, according to another aspect of the present invention, there is provided a patch comprising: a flexible base material; and a medicinal component contained in the base material, wherein the patch is affixed to an affected area by an adhesive surface provided on the base material. And a support member attached to the non-stick side of the base material, and a belt provided on the support member, wherein the support member can maintain the flatness of the base material. It has a size and rigidity, and is attached to the non-stick side of the substrate by an attaching means having an adhesive force lower than the adhesive force of the adhesive surface of the substrate, and the patch is attached to the affected area. Thereafter, the support member including the belt portion is peeled off from the base material, and a patch is obtained, wherein the base material and the medicinal component are used.

Further, the support member is formed in a sheet shape having substantially the same size as the base material, and the attaching means is provided on one surface of the sheet-like support member, and is provided based on the adhesive strength of the adhesive surface of the base material. It may be constituted by another adhesive surface having a low viscosity.

Further, the belt portion is provided on the other surface of the support member, and can be constituted by a cylindrical portion or a pocket portion into which a finger can be inserted.

The support member is made of a cloth such as a cotton cloth, a regenerated cellulose cloth, a chemical fiber cloth, a nonwoven cloth, a paper such as a Japanese paper and a craft paper, a hard vinyl chloride, a polypropylene, a polyethylene, a polyester, a polyamide, a polycarbonate, or the like. And a copolymer thereof, a plastic film such as cellophane, a metal flake, or a laminate thereof.

BRIEF DESCRIPTION OF THE FIGURES

FIG. 1 shows a patch support according to a first embodiment of the present invention, and a release paper thereof is partially peeled. It is a perspective view seen from the adhesive surface side in a separated state,

FIG. 2 is a perspective view of the patch support shown in FIG. 1 viewed from a surface opposite to the adhesive surface,

FIG. 3 is a perspective view showing a state in which the patch support shown in FIG. 1 is attached to a patch.

FIG. 4 is a perspective view showing a state in which the patch, to which the patch support is attached as shown in FIG. 3, is attached to the affected area,

FIG. 5 is a perspective view of a patch according to the second embodiment of the present invention. BEST MODE FOR CARRYING OUT THE INVENTION

The present invention will be described in more detail with reference to the accompanying drawings. First, with reference to FIG. 1 to FIG. 4, a patch support according to a first embodiment of the present invention will be described. Note that the patch support 1 of the present embodiment is used together with a patch using a soft and thin base material similar to the above-mentioned conventional example.

Fig. 1 is a perspective view of the support with the release paper partially peeled from the support, viewed from the adhesive side of the support. Fig. 2 is a perspective view of the support, also viewed from the side opposite to the adhesive. is there. FIG. 3 is a perspective view showing a state in which the support is stuck to a patch, and FIG. 4 is a perspective view showing a state in which the patch stuck to the support is stuck to an affected part.

As shown in FIGS. 1 to 4, the patch support 1 according to the present embodiment includes a support member 2 having an adhesive surface 3 on one surface thereof, and a support member 2 provided on a surface of the support member 2 opposite to the adhesive surface 3. And a release paper 5 attached to the adhesive surface 3 of the support member 2. The supporting member 2 is made of cloth such as cotton cloth, regenerated cellulose cloth, chemical fiber cloth, and non-woven cloth, paper such as Japanese paper and craft paper, hard vinyl chloride, polypropylene, polyethylene, polyester, polyamide, polycarbonate, And a plastic film such as a copolymer thereof or cellophane, etc., and has an appropriate rigidity. In order to provide such rigidity, the support member 2 may be formed of a laminate of these various materials such as papers, cloths, films, and the like. Furthermore, the support member 2 is made of metal It is also conceivable to get In the present invention, the material, size, and shape of the support member are not particularly limited. That is, the support member may have any shape, but the point is that the support member has a size and rigidity enough to maintain the flatness of the base material when bonded to the base material. Just do it. It is preferable that the base material has substantially the same shape and size as the base material, since the base material is easily supported sufficiently, the manufacturing is easy, and the usability is good. Note that the rigidity of the support member does not prevent the base material from bending in accordance with the shape of the curved portion when the patch is applied to a curved portion such as a shoulder or a waist, for example. That is, the rigidity of the support member is sufficient if the flatness of the base material can be maintained to such an extent that the base material can be prevented from breaking up quickly so that the adhesive surfaces of the base material do not stick.

The adhesive surface 3 has a viscosity lower than the viscosity of the adhesive surface of the patch. The support member 2 needs to be separated from the base without sticking the adhesive surface of the patch (substrate) from the affected part after the patch is applied to the affected part. In the present invention, the method of bonding the support member to the substrate is not limited. In short, the method of non-sticking the substrate by an adhesive means having an adhesive force lower than the adhesive force of the adhesive surface of the adhesive agent (substrate) is not limited. It only has to be attached to the side. Therefore, for example, the support member 2 may be bonded to the base material by fixing the adhesive member 3 with a double-sided tape during use without providing the adhesive surface 3. However, in this embodiment, the support member 2 is previously formed with the adhesive surface 3 with an adhesive having a viscosity lower than the viscosity of the adhesive surface of the patch (substrate), and then covered with a release paper 5. At the time of use, the release paper 5 is peeled off so that the adhesive surface 3 and the base material 9 are bonded together. This is preferable because the two adhesive surfaces having different viscosities can be integrally manufactured during the production of the patch, and the support of the base material by the support member is also stable.

The belt portion 4 is for attaching the support member 2 to a finger or the like of a user's hand. In the present invention, the material, size and shape of the belt portion are not particularly limited. That is, the belt portion may be of any size and shape, and is not particularly formed separately from the support member, but is appropriately cut so that a finger or the like can be inserted, for example. It is also possible to put it in. In this embodiment, the adhesive surface of the support member 2 is used. A belt-like sheet having substantially the same shape and the same size as the support member 2 was attached to the surface on the side opposite to 3, and the belt portion 4 was formed into a tubular shape by bonding both side edges of the belt-like sheet. This makes it possible to insert a finger or the like between the support member 2 and the cylindrical belt portion 4 and easily and stably apply the patch while maintaining substantially the flatness of the support member and thus the base material. Can be. In addition, cloth, paper, nonwoven fabric, polymer film, and the like can be used as the material of the band-shaped sheet. In this embodiment, a transparent polymer film is used.

The release paper 5 covers the adhesive surface 3 of the support member 2 until use, and prevents the adhesive surface 3 from being stained and dried. Reference numeral 6 denotes a patch using a soft and thin substrate, and 7 denotes a protective film for covering the adhesive surface of the patch 6.

In the patch support 1 of the present embodiment, the viscosity of the adhesive surface 3 needs to be smaller than the viscosity of the adhesive surface of the patch 6, but there is no particular limitation on this viscosity value. May be appropriately selected from commonly used materials.

Acrylic, vinyl acetate, polyvinyl alcohol, vinyl chloride, polyamide, polyethylene, cell-based adhesives, gelatin, etc. are used as the adhesive for forming the adhesive surface. It is possible.

Now, a method of using the patch support 1 of the present example will be described.

In order to use the patch support 1, first, as shown in FIGS. 1 and 2, the release papers 5, 5 are peeled from the patch support 1 to expose the adhesive surface 3. It is preferable that the release papers 5 and 5 be completely peeled off from the adhesive patch support 1 to expose the entire surface of the adhesive surface 3. As will be described later, the release papers 5 may be discarded after being peeled off, unless the patch support 1 is used again.

Next, the adhesive surface 3 of the adhesive support 1 is attached to the surface of the adhesive 6 opposite to the adhesive surface. Thereby, as shown in FIG. 3, a patch 6 integrated with the patch support 1 is obtained.

Subsequently, as shown in FIG. 4, for example, a finger of a hand is inserted between the support member 2 and the belt portion 4, and in this state, that is, the patch 6 is applied to the hand of the user via the patch support 1. Peel off the protective film 7 of the patch 6 shown in Fig. 3 while supporting the patch After exposing the adhesive surface of 6, the patch 6 is applied to the desired affected area.

Finally, the patch support 1 is slowly peeled off the patch 6 attached to the affected area. In addition, the patch support 1 peeled off from the patch 6 is stored by pasting the release papers 5 and 5 again on the adhesive surface 3, and is used again when pasting another patch 6. Although it is possible to do so, since it is intended for drugs, it is desirable to dispose it for sanitation.

In this example, the patch support 1 formed to be approximately the same size as the patch 6 was used as it is.For example, when the patch 6 is cut into small pieces depending on the affected area and used. In addition, the patch support 1 may be cut and used accordingly. Here, an example of a method for manufacturing the patch support according to the present example will be described.

To manufacture the adhesive patch support 1, first, an adhesive having a viscosity smaller than the viscosity of the adhesive surface of the adhesive 6 is applied to the support member, and at the same time, a film for forming a release paper is attached.

Next, the supporting member to which the film is attached is passed through a drying oven.

Further, after aging the intermediate product thus completed, a film for forming a belt portion is placed thereon, and both ends thereof are heat-sealed.

After the completion of the belt portion, a slit for separating the release paper into two pieces from the center and a cut to the belt portion may be added as necessary.

Next, a patch according to a second embodiment of the present invention will be described with reference to FIG. As shown in FIG. 5, the patch 8 according to the present embodiment is previously provided on the surface opposite to the adhesive surface (not shown) of the base material 9 with the support in the above-described support of the first embodiment. It has a support member and a belt portion having substantially the same configuration. Note that the patch 8 of the present embodiment does not have the equivalent to the release papers 5, 5 in the support of the first embodiment described above.

That is, in the same manner as in the above-described conventional example and the first embodiment, the patch 8 of the present embodiment is composed of a soft and thin base material 9 and a plaster applied to the base material 9 (shown in FIG. And the plaster contains a medicinal ingredient such as anti-inflammatory and analgesic. Further, in order to prevent the adhesive surface coated with the plaster from being stained or dried before use, a protective film 10 for covering the adhesive surface is provided. The patch 8 of the present example was further provided on a support member 12 mounted on the surface of the base material 9 opposite to the adhesive surface, and on a surface of the support member 12 opposite to the bonding surface. It has a belt portion 13.

The support member 12 is made of the same material as the support member 2 in the first embodiment described above, and has an appropriate rigidity. The support member 12 is formed to have substantially the same size as the base material 9 and is mounted on the surface of the base material 9 opposite to the adhesive surface. In addition, the support member 12 needs to be separated from the base material 9 without sticking the adhesive surface of the base material 9 from the affected part after the patch 8 is applied to the affected part. In the present invention, the method of bonding the support member to the substrate is not limited. In short, the method of bonding the support member to the non-adhering side of the substrate by an adhesive means having an adhesive force lower than the adhesive force of the adhesive surface of the adhesive agent (substrate) It should just be stuck to. Therefore, for example, the support member may be bonded to the base material by simply fixing a plurality of places with clips or the like without using an adhesive. However, in the patch 8 of the present embodiment, the support member 12 is bonded to the substrate 9 with an adhesive having a viscosity lower than that of the adhesive surface of the substrate 9, that is, the adhesive surface of the adhesive. ing. In this way, two adhesive surfaces having different viscosities can be integrally manufactured during the production of the patch, and the support of the base material by the support member is also stable, which would be preferable.

The belt portion 13 has the same function as the belt portion 4 in the first embodiment. In this embodiment, the belt portion 13 is supported on the surface of the support member 12 opposite to the surface bonded to the base material 9. A band-like sheet having substantially the same shape and the same size as the holding member 12 is attached, and the three sides of the band-like sheet are adhered to each other to form a bag.

Now, the patch 8 of this example is obtained by peeling the protective film 10 from the adhesive surface of the base material 9 and then inserting a finger or the like of the hand into the bag-like belt portion 13 from the opening side. However, it is sufficient to position the patch 8 at the desired affected area and then paste it. It is to be noted that, after the attachment, the support member 12 is loosely peeled off and separated from the substrate 9 in the same manner as in the first embodiment described above. Although the present invention has been described with reference to the specific embodiments, it is easily possible for those skilled in the art to apply the present invention to various other embodiments.

For example, in the first and second embodiments described above, a support used when a patch as an external anti-inflammatory analgesic is applied to an affected part and a patch containing the support are described.

However, the present invention provides, in addition to antiphlogistic analgesics, antipyretic antiphlogistic analgesics, steroid anti-inflammatory agents, vasodilators, hypertension / arrhythmic agents, antihypertensive agents, antitussives / expectorants, antitumor agents, local anesthesia Agents, hormones, asthma, nasal allergy treatment, antihistamine, anticoagulant, antispasmodic, cerebral circulation, metabolic improver, antidepressant, anxiolytic, vitamin D preparation, hypoglycemic, antiulcer, sleep , Antibiotics, adrenergic bronchodilators, narcotic analgesics, diuretics, sedatives, antifungals, bactericides, calcium antagonists, antiparkinson, anticholinergic, shoulder stiffness, muscle pain remedies Percutaneously absorbable medicinal ingredients such as low back pain remedy, antidepressants, decubitus ulcers, skin ulcer treatments, cold-sensitive skin irritants, warm-sensitive skin irritants, and harmful UV absorbers Included It can be applied also for many of the pasting agent.

In particular, since the drug does not pass through the gastrointestinal tract, there is no need to worry about gastrointestinal disorders, which is a side effect of non-steroid anti-inflammatory drugs. Insulin, a diabetic drug, is currently only available as an injection, but by developing a patch form, patients will not only be free from pain during injection, but will also benefit from ease of operation and convenience. You can also take a bath.

In addition, regardless of the application, a patch for medical use or medical rescue, which is directly attached to the skin for the purpose of a patch test, blood stoppage, disinfection, protection, etc., and a topical or circulatory system Dermal patch attached to the skin for the purpose of drug administration to the skin, and a skin care sheet containing an extract of animal tissue or plant or crude drug as a moisturizing component, etc. for back, shoulder, etc. It is widely applied to hair removal tapes, hair dressing materials, surgical tapes, etc. to which hair removal adhesive has been applied when used to remove stains and breakouts, pimples, fish eyes, and octopuses.

That is, the present invention relates to an adhesive (adhesion) in which a flexible substrate and a therapeutic agent are mixed. It is widely applicable as long as it has a drug layer and is applied to the skin or the like, regardless of the use of the patch. For example, the present invention can be applied to a pressure-sensitive tape or the like containing a ditroglycerin solution as a therapeutic agent for angina pectoris and congestive heart failure in the adhesive portion of the tape. Further, an S-blocker is contained in a polymer matrix, and the matrix itself has no skin adhesiveness, and can be applied to a patch or the like which tightly administers a / 8-blocker in the matrix to the skin with an adhesive tape. In these cases, the tape itself corresponds to a flexible substrate. It is also applicable to percutaneous absorption anesthetics and the like in which an adhesive layer carried on a flexible base material contains a lidocaine hydrochloride solution as a local anesthetic. Further, the present invention is applied not only to a transdermal absorption plaster sheet, but also to a so-called dressing sheet, such as a waterproofing film, a breathable sheet for covering a wound, and the like. Further, in the first and second embodiments described above, a relatively large patch is described, in which several fingers are inserted between the support member and the belt portion, and are attached. As apparent from the first paragraph of the present invention, for example, the present invention provides a therapeutic adhesive tape or sheet provided with a thin layer of a pressure-sensitive adhesive layer mixed with an antifungal agent or the like for the purpose of treating athlete's foot. It is needless to say that the present invention is also applied to smaller patches, such as sticking to a finger or the like.

On the other hand, as can be understood from the first aspect of the present invention, as long as it is provided with a flexible base material and is attached to an affected area, for example, burns, trauma, skin wounds using chitin, etc. It can be applied not only to tapes for treatment or protection of wounds such as but also to adhesive tapes or sheets such as adhesive tapes or sheets for protecting the affected area where a simple gauze containing no drug is attached to the base material. is there. In addition, it is needless to say that the present invention is also applied to a poultice for reducing stiff shoulders or the like in which a magnet (magnetic material) is attached to a base material. As described above, the present invention can be applied to many patches containing the active ingredient of a transdermally absorbable drug. Examples of antipyretic and anti-inflammatory drugs include indomethacin, diclofenac sodium, methyl salicylate , Monoglycol salicylate, aspirin, acetaminophen, ibuprofen, sulindac, naproxen, ketoprofen, flufenamic acid, ibufenac, fempfen, al Non-steroid anti-inflammatory drugs such as clofenac, phenylbutazone, mefenamic acid, bendazac, piroxicam, flurbiprofen, pentazocine, buprenorphine hydrochloride, and butorphanol tartrate.

Examples of steroid anti-inflammatory agents include hydrocortisone, prednisolone, fluocinolone acetate, fludoxycortide, methylprednisolone, hydrocortisone acetate, triamcinolone acetate, dexamethasone, betamethasone acetate, Examples include diflucortron valerate, clobesol propionate, and fluocinonide.

Examples of vasodilators include diltiazem, verapamil, pentaerythritol tetranitrate, dipyridamole, isosorbide dinitrate, difludipine, nitroglycerin and the like.

Examples of agents for hypertension and arrhythmia include bupranolol, propanolol, athenolol, pindolol, quinidine sulfate, adimarin, alprenolol hydrochloride, metprolol tartrate, nadolol, timolol maleate, disopyramide and the like.

Examples of antihypertensive agents include clonidine hydrochloride, captopril, prazosin hydrochloride, pentolol sulfate, guanavenz acetate, guanfacine hydrochloride, bunazosin hydrochloride, elanapril maleate, arotinolol hydrochloride, and bunitrolol hydrochloride.

Examples of antitussive expectorants include propoterol hydrochloride, terbutaline sulfate, phenoterol hydrobromide, rlobbuterol hydrochloride, amproxol hydrochloride, pyrbuterol hydrochloride, mabuterol hydrochloride, clenbuterol hydrochloride, trimethokinol hydrochloride, and formoterol fumarate. No.

Examples of the antitumor agent include 5-fluorouracil, 1- (2-tetrahydrofurfuryl) -15-fluorouracil, mitomycin C and the like.

Examples of the local anesthetic include benzocaine, procarin, lidocaine, and tetracaine. Examples of hormonal agents include steroid hormones such as estrogen, estradiol, testosterone, and progesterone, peptide hormones such as insulin, and prostaglandins.

Examples of the therapeutic agent for asthma and nasal allergy include ketotifan fumarate, azelastine hydrochloride, sodium cromoglycate and the like.

Examples of the antihistamine include cycloheptadine hydrochloride, diphenhydramine hydrochloride, fenbenzamine, mequitazine and the like.

Examples of anticoagulants include heparin.

Examples of antispasmodics include scopolamine and clofluverol.

Examples of cerebral circulation and metabolism improving agents include vinpocetine, flunarizine hydrochloride, dicardipine hydrochloride, provincamine fumarate, dihydroergotoxine mesylate, ifenprodil tartrate, isoxsuprine hydrochloride and the like.

Examples of antidepressants / anxiolytics include maprotiline hydrochloride, etizolam, diazebam, promazepam, amitributyline hydrochloride, mianserin hydrochloride and the like. Examples of vitamin D preparations include alfacalcidol and ergocalciferol.

Examples of hypoglycemic agents include glibenclamide, gliclazide and the like. Examples of anti-ulcer agents include crepopride malate, famotidine, glycopyrronium bromide and the like.

Examples of hypnotics include phenobarbital, amobarbital, etc.o

Examples of antibiotics include tetracycline, chloramphenicol, etc.o

Α- [1- (Methylamino) ethyl] benzenemethanol (ephdrine) as an adrenergic bronchodilator, 有用 -phenyl- な 1- [2- (2-phenylethyl) 1-4 な useful as a narcotic analgesic Piberidinyl] propane amide, as a diuretic, 6-chloro-3,4-dihydro-1 2Η-1,2,4-pentazo Thiadiazine-1 7-sulfonamide 1,1-dioxide, 2-diphenylmethoxy-N, N-dimethylethaneamine (diphenhydramin) as an antihistamine, estrogen estrler 1,3,5 (10) — Trien-1,3,8 / 8-diol (estradiol), antispasmodic agent ・ 5-hythyl-5, -phenyl-1,2,4,6 (1H, 3H, 5H) —Pirimi as a hypnotic and sedative Jin Trion and the like.

Examples of the bactericide include chlorhexidine diglyconate, acrynol and the like.

Examples of coronary vasodilators include nitroglycerin, isosorbitol dinatrate, glycol dinitrate, triethanolamine trinitrate, pentaerythritol tetranitrate, propachinitritol, nicorandil and the like. Examples of the tranquilizer include flupanazine, thioridasin, and diazepam.

It may also contain calcium antagonists, antiparkinson agents, anticholinergic agents and the like. For example, examples of suitable contained substances include perapamil, galopamil, anipamil, piperidene, haloperidol, and the like.

In addition, antitussives and antidepressants include morphine hydrochloride and morphine sulfate. In addition, as a therapeutic agent for bedsores, there are a pressure ulcer medicine containing a mixture of sucrose, povidone and glycerin, and a patch for treating skin ulcer.

Cool-sensitive skin irritants include 1-menthol, d1-camphor, thymol, d-borneol and the like.

Examples of warm skin irritants include red pepper, vanillyl nonylate, capsaicin, ginger extract, cantharis tincture, and cantharidin.

In the treatment of skin diseases such as vitiligo vulgaris and psoriasis using psoralen or its derivatives in combination with ultraviolet light, it absorbs ultraviolet rays in the wavelength range harmful to the skin and transmits only those in the wavelength range useful for treatment. A salicylic acid-based compound that can be There is also a harmful ultraviolet ray absorbing adhesive sheet composed of a composition containing 2,2'-methylene-bis (4-ethyl-16-tert-butylphenol).

Further, a cosmetic pack containing a beauty active substance such as hyaluronic acid, amino acid, protein, hormone, natural substance such as placental extract substance, surfactant, skin lightening substance, vitamin and the like may be used.

A hair removal tape or a poultice containing a hair removal agent may be used.

Abdominal distension · Poor bowel movement · A paste containing miso (miso sheet) as a patch for the treatment of fever may be used.

Further, as a soluble hemostatic material for protecting the wound surface for the purpose of treating bleeding, a material containing oxycellulose, oxidized collagen, sodium cellulose, calcium alginate and the like may be used. Industrial applicability

Since the support of the present invention has the above-described configuration, even when a conventional patch made of a soft base material is used, the base material can be temporarily made rigid at the time of application. Therefore, even when the protective film or the like is peeled off from the patch or when the patch is applied to a desired affected area after the protective film or the like is peeled off, it is possible to effectively prevent the sticking of the adhesive surfaces from each other. it can.

Further, by forming the belt portion into a tubular shape or a bag shape through which a finger can be inserted, for example, over the entire width of the support member, when the patch is stuck to a desired affected part, Since several fingers can be inserted between the belt and the belt, the patch can be applied smoothly, and when the support is released after the patch is applied. This can be done smoothly.

As described above, even with a patch having a soft base material, it is possible to prevent the adhesive surfaces from sticking to each other, and to provide a patch support for the patch which can be easily attached to an affected area such as a shoulder, a back, and a waist. Its industrial value is of great value because it can be provided and can be applied to patches for a wide range of uses. In the case of a patch having the same structure as that of the support on the surface of the substrate opposite to the adhesive surface, the presence of the support member allows the substrate to have rigidity. The adhesive surfaces do not stick together when the film or the like is peeled off, or when the protective film or the like is peeled off and attached to a desired affected part. Further, similarly to the above-described support device, the belt portion is formed in a tubular shape or a bag shape through which a finger of a hand can be inserted, for example, over the entire width of the support member. Since a plurality of fingers can be inserted in a state in which the fingers are arranged in between, the patch can be smoothly applied and the support member can be smoothly separated when the support member is separated from the base material.

As described above, while making use of the advantages of a patch having a soft base material, it provides a patch that does not stick to the adhesive surfaces and is easy for patients to apply to affected areas such as shoulders, back, and waist. This makes it easier for children, the physically handicapped, and the elderly with poor vision to stick to the affected area and has great medical value.

Claims

The scope of the claims

1. When a patch having a flexible base material is applied to an affected area, the support is used temporarily to support the base material of the patch,

A support member to be bonded to the non-stick side of the base material,

A belt portion provided on the support member,

The support member has a size and rigidity capable of maintaining the flatness of the base material when bonded to the base material, and is provided by an attachment means having an adhesive force lower than the adhesive force of the adhesive surface of the patch. A patch support, which is bonded to the non-stick side of the base material.

2. The patch support according to claim 1, wherein the support member is formed in a sheet shape having substantially the same size as the base material, and the attaching means is provided on one surface of the sheet-like support member. A patch support characterized by being constituted by another adhesive surface having a viscosity lower than the adhesive force of the adhesive surface of the adhesive patch.

3. The patch support according to claim 2, wherein the belt portion is provided on the other surface of the support member, and is configured by a tubular portion or a bag-like portion through which a finger of a hand can be inserted. A support for patches, characterized in that:

4. The patch support according to claim 2, wherein the other adhesive surface is covered with a release paper.

5. The patch support according to any one of claims 1 to 4, wherein the support member is a cloth such as a cotton cloth, a regenerated cellulose cloth, a chemical fiber cloth, a non-woven cloth, a paper such as a Japanese paper, a craft paper, or a rigid vinyl chloride. A support for a patch, comprising a plastic film such as polypropylene, polyethylene, polyester, polyamide, polycarbonate, a copolymer thereof, a cellophane or the like, a metal flake, or a laminate thereof.

6. A patch comprising a flexible base material and a medicinal component contained in the base material, which is stuck to an affected part by an adhesive surface provided on the base material,

A support member stuck on the non-stick side of the base material,

A belt portion provided on the support member,

The support member has a size and rigidity capable of maintaining the flatness of the base material, and is attached to the non-stick side of the base material by an attachment unit having an adhesive force lower than the adhesive force of the adhesive surface of the base material. Has been

A patch characterized in that after the patch has been stuck to the affected area, the support member including the belt portion is peeled off from the base material, and the base material and the medicinal component are used.

7. The patch according to claim 6, wherein the support member is formed in a sheet shape having substantially the same size as the base material, and the attaching means is provided on one surface of the sheet-like support member. An adhesive patch comprising another adhesive surface having a viscosity lower than the adhesive force of the adhesive surface of the material.

8. The patch according to claim 7, wherein the belt portion is provided on the other surface of the support member, and is constituted by a tubular portion or a bag-like portion into which a finger can be inserted. Support for adhesive patches.

9. The patch according to claim 6, wherein the support member is a cloth such as a cotton cloth, a regenerated cellulose cloth, a chemical fiber cloth, a nonwoven cloth, a paper such as a Japanese paper, a craft paper, a hard vinyl chloride, or a polypropylene. An adhesive patch comprising: polyethylene, polyester, polyamide, polycarbonate, a copolymer thereof, a plastic film such as cellophane, a metal flake, or a laminate thereof.