WO1998054209A3 - Mafa humaine - Google Patents

Mafa humaine Download PDF

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Publication number
WO1998054209A3
WO1998054209A3 PCT/GB1998/001572 GB9801572W WO9854209A3 WO 1998054209 A3 WO1998054209 A3 WO 1998054209A3 GB 9801572 W GB9801572 W GB 9801572W WO 9854209 A3 WO9854209 A3 WO 9854209A3
Authority
WO
WIPO (PCT)
Prior art keywords
mafa
associated antigen
cell function
mast cell
human mast
Prior art date
Application number
PCT/GB1998/001572
Other languages
English (en)
Other versions
WO1998054209A2 (fr
Inventor
Ellen Louise Hewitt
Maria Bardina Antonia C Lamers
Alan Lamont
David Hugh Williams
Original Assignee
Peptide Therapeutics Ltd
Ellen Louise Hewitt
Maria Bardina Antonia C Lamers
Alan Lamont
David Hugh Williams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peptide Therapeutics Ltd, Ellen Louise Hewitt, Maria Bardina Antonia C Lamers, Alan Lamont, David Hugh Williams filed Critical Peptide Therapeutics Ltd
Priority to AU76670/98A priority Critical patent/AU7667098A/en
Publication of WO1998054209A2 publication Critical patent/WO1998054209A2/fr
Publication of WO1998054209A3 publication Critical patent/WO1998054209A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des polypeptides, des séquences de nucléotides, des anticorps ou leurs fragments, des ligands et des compositions, ainsi que leur utilisation dans les domaines médicaux de l'inflammation et de l'allergie, dont des exemples concernent des maladies, telles que la polyarthrite rhumatoïde et l'asthme. Elle concerne, de plus, un procédé servant à produire ces polypeptides. Elle propose des méthodes de traitement de ces maladies basées sur des agents conçus en combinaison avec le clonage de la molécule humaine MAFA. Une mise en application de l'invention consiste à empêcher des événements d'activation cellulaire in vivo, ce qui pourrait conduire à des thérapies servant à empêcher la croissance tumorale.
PCT/GB1998/001572 1997-05-31 1998-05-29 Mafa humaine WO1998054209A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU76670/98A AU7667098A (en) 1997-05-31 1998-05-29 Human mafa

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711148.8A GB9711148D0 (en) 1997-05-31 1997-05-31 Human MAFA
GB9711148.8 1997-05-31

Publications (2)

Publication Number Publication Date
WO1998054209A2 WO1998054209A2 (fr) 1998-12-03
WO1998054209A3 true WO1998054209A3 (fr) 1999-03-11

Family

ID=10813276

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1998/001572 WO1998054209A2 (fr) 1997-05-31 1998-05-29 Mafa humaine

Country Status (3)

Country Link
AU (1) AU7667098A (fr)
GB (1) GB9711148D0 (fr)
WO (1) WO1998054209A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1572987A4 (fr) * 2000-02-03 2005-11-30 Nuvelo Inc Acides nucleiques et polypeptides
US7056677B2 (en) 2000-03-17 2006-06-06 Gemini Science, Inc. Soluble mast cell function associated antigen (MAFA) pharmaceutical compositions and methods of making and using them
WO2003057252A1 (fr) * 2002-01-03 2003-07-17 Tanox, Inc. Proteines membranaires de mastocytes exprimees
WO2020012478A2 (fr) * 2018-07-11 2020-01-16 Immunity Pharma Ltd. Composés peptidiques et leurs utilisations thérapeutiques
CN114621320B (zh) * 2020-12-14 2024-05-24 清华大学 一种可用于减缓glp-1酶解的短肽及其组合物

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010231A1 (fr) * 1989-03-02 1990-09-07 Replico Medical Ab Discrimination entre des anticorps contre htlv-i, htlv-ii ou des retrovirus apparentes, des nouveaux peptides, detection d'anticorps et kits d'immunoanalyse
WO1993005175A1 (fr) * 1991-09-11 1993-03-18 Medical Research Council Perfectionnements apportes aux amorces et aux sondes oligonucleotides
WO1995027734A1 (fr) * 1994-04-08 1995-10-19 Yeda Research And Development Co. Ltd. Molecule d'adn codant un antigene associe a la fonction des mastocytes (mafa)
WO1996001114A1 (fr) * 1994-07-06 1996-01-18 Brandeis University Procede de traitement et de prevention de la maladie d'alzheimer
WO1996003649A1 (fr) * 1994-07-22 1996-02-08 The University Of North Carolina At Chapel Hill PEPTIDES SE FIXANT AUX SH3 DE Src ET LEURS METHODES D'ISOLEMENT ET D'UTILISATION
DE4432942A1 (de) * 1994-09-15 1996-03-21 Radulescu Razvan T Dr Med M D Synthetic Inducible Biological Response Amplifiers (SIBRAs) und ihre potentiellen Anwendungen in der Medizin
US5541109A (en) * 1994-04-19 1996-07-30 Rhone-Poulenc Rorer Pharmaceuticals Inc. Expression cloning of c-src SH3-domain binding proteins
WO1997030074A1 (fr) * 1996-02-16 1997-08-21 Cytogen Corporation Isolation et utilisation de peptides de liaison de sh3

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010231A1 (fr) * 1989-03-02 1990-09-07 Replico Medical Ab Discrimination entre des anticorps contre htlv-i, htlv-ii ou des retrovirus apparentes, des nouveaux peptides, detection d'anticorps et kits d'immunoanalyse
WO1993005175A1 (fr) * 1991-09-11 1993-03-18 Medical Research Council Perfectionnements apportes aux amorces et aux sondes oligonucleotides
WO1995027734A1 (fr) * 1994-04-08 1995-10-19 Yeda Research And Development Co. Ltd. Molecule d'adn codant un antigene associe a la fonction des mastocytes (mafa)
US5541109A (en) * 1994-04-19 1996-07-30 Rhone-Poulenc Rorer Pharmaceuticals Inc. Expression cloning of c-src SH3-domain binding proteins
WO1996001114A1 (fr) * 1994-07-06 1996-01-18 Brandeis University Procede de traitement et de prevention de la maladie d'alzheimer
WO1996003649A1 (fr) * 1994-07-22 1996-02-08 The University Of North Carolina At Chapel Hill PEPTIDES SE FIXANT AUX SH3 DE Src ET LEURS METHODES D'ISOLEMENT ET D'UTILISATION
DE4432942A1 (de) * 1994-09-15 1996-03-21 Radulescu Razvan T Dr Med M D Synthetic Inducible Biological Response Amplifiers (SIBRAs) und ihre potentiellen Anwendungen in der Medizin
WO1997030074A1 (fr) * 1996-02-16 1997-08-21 Cytogen Corporation Isolation et utilisation de peptides de liaison de sh3

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
C. GELLER-BERNSTEIN ET AL: "Antibodies Specific to Membrane Components of Rat Mast Cells Are Cross-Reacting with Human Basophils", INT ARCH ALLERGY IMMUNOL, vol. 105, 1994 *
PETR BOCEK, JR. ET AL: "Analysis of the Genes Encoding the Mast Cell Function-Associated Antigen and Its Alternatively Spliced Transcripts 1,2", THE JOURNAL OF IMMUNOLOGY, vol. 158, no. 7, 1997 *
RYAN JC ET AL: "Divergent functions of lectin-like receptors on NK cells", IMMUNOL REV, February 1997 (1997-02-01), pages 79 - 89 *

Also Published As

Publication number Publication date
GB9711148D0 (en) 1997-07-23
AU7667098A (en) 1998-12-30
WO1998054209A2 (fr) 1998-12-03

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