WO1998046277A2 - Compensation de l'humidite pour l'etalonnage a zero des cellules electrochimiques dans des dispositifs de mesure de gaz respiratoire - Google Patents
Compensation de l'humidite pour l'etalonnage a zero des cellules electrochimiques dans des dispositifs de mesure de gaz respiratoire Download PDFInfo
- Publication number
- WO1998046277A2 WO1998046277A2 PCT/US1998/006254 US9806254W WO9846277A2 WO 1998046277 A2 WO1998046277 A2 WO 1998046277A2 US 9806254 W US9806254 W US 9806254W WO 9846277 A2 WO9846277 A2 WO 9846277A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- respiratory gas
- gas
- sample
- respiratory
- humidity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
Definitions
- electrochemical fuel cells are used in conjunction with additional circuitry to measure the amount of a specific gas within a respiratory gas stream.
- a monitor for measuring the concentration of nitric oxide and nitrogen dioxide electrochemical fuel cells are used to generate an electrical signal indicative of the respective concentrations of nitric oxide and nitrogen dioxide.
- Such a monitor is useful during the administration of nitric oxide to a patient for medical purposes.
- United States Patent No. 5,485,827, Zapol et al. which discusses the method of treating patients with nitric oxide and United States Patent No. 5,558,083, Bathe et al., which discloses a nitric oxide delivery system of which a gas monitor is one element.
- the accuracy of respiratory gas measurements taken by electrochemical fuel cells is affected by changes in humidity. Such changes come more apparent after a monitoring bench containing fuel cells has been zeroed and then returned to the sampling mode where a measurement is taken of a respiratory gas sample. The difference in humidity between the sampling gas stream and the zeroing gas stream causes a zero drift in the fuel cell readings.
- a six inch piece of Nafion® tubing is used in the present invention after the pneumatics manifold which switches between the two gas streams and the fuel cell bench in order to equilibrate the humidity in both the sample and zero gas streams. The addition of this Nafion® tubing eliminates the zero drift between the two gas sources allowing for an accurate zeroing of the nitrogen oxide and nitrogen dioxide fuel cells.
- FIG. 1 is a diagram of the gas stream flow components of a respiratory gas monitor according to the present invention.
- FIG. 1 depicts the major components of a respiratory gas monitor according to the present invention through which the sample and zero gases flow.
- the pneumatic manifold 10 controls the source of the gas stream input to the bench 20 containing the electrochemical fuel cells for the measurement of nitric oxide, nitrogen dioxide and oxygen.
- the manifold 10 enables the monitor control to select between inputting a sample of the respiratory gas stream into the sample inlet 40 or a sample of a calibration gas into scrubber 30.
- a Nafion® tube or other hydrophilic tube 50 is placed between manifold 10 to bench 20 to reduce the amount of moisture in the gas stream.
- Vacuum pump 60 provides the Vacuum necessary to draw the sample or calibration (zeroing) gases through the system.
- the next configuration tested used humidified sample gas and dry room air gas.
- the system was zeroed in each of four configurations: (1) no Nafion; (2) 4 inches of Nafion; (3) 6 inches of Nafion; and (4) 16 inches of Nafion. After zeroing the system was switched to humid sample gas and the variance in the relative humidity of the gas readings taken on the far side of the bench was recorded as set forth in the following Table 2.
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU68726/98A AU6872698A (en) | 1997-04-16 | 1998-03-30 | Humidity compensation for fuel cell zeroing in respiratory gas measurement |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4325097P | 1997-04-16 | 1997-04-16 | |
US60/043,250 | 1997-04-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998046277A2 true WO1998046277A2 (fr) | 1998-10-22 |
WO1998046277A3 WO1998046277A3 (fr) | 1999-03-04 |
Family
ID=21926239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/006254 WO1998046277A2 (fr) | 1997-04-16 | 1998-03-30 | Compensation de l'humidite pour l'etalonnage a zero des cellules electrochimiques dans des dispositifs de mesure de gaz respiratoire |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU6872698A (fr) |
WO (1) | WO1998046277A2 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003017837A1 (fr) * | 2001-08-28 | 2003-03-06 | Phase-In Ab | Dispositif d'analyse quantitative de gaz respiratoires |
WO2010030226A1 (fr) * | 2008-09-15 | 2010-03-18 | Phasein Ab | Ligne d'échantillonnage de gaz pour gaz respiratoires |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5038792A (en) * | 1988-06-29 | 1991-08-13 | Mault James R | Oxygen consumption meter |
US5042500A (en) * | 1990-06-18 | 1991-08-27 | Medical Graphics Corporation | Drying sample line |
US5284160A (en) * | 1991-11-13 | 1994-02-08 | Dryden Gale E | Consolidated anesthesia circuit |
US5485827A (en) * | 1990-12-05 | 1996-01-23 | The General Hospital Corporation | Methods and devices for treating plumonary vasoconstriction and asthma |
US5558083A (en) * | 1993-11-22 | 1996-09-24 | Ohmeda Inc. | Nitric oxide delivery system |
-
1998
- 1998-03-30 AU AU68726/98A patent/AU6872698A/en not_active Abandoned
- 1998-03-30 WO PCT/US1998/006254 patent/WO1998046277A2/fr active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5038792A (en) * | 1988-06-29 | 1991-08-13 | Mault James R | Oxygen consumption meter |
US5042500A (en) * | 1990-06-18 | 1991-08-27 | Medical Graphics Corporation | Drying sample line |
US5485827A (en) * | 1990-12-05 | 1996-01-23 | The General Hospital Corporation | Methods and devices for treating plumonary vasoconstriction and asthma |
US5284160A (en) * | 1991-11-13 | 1994-02-08 | Dryden Gale E | Consolidated anesthesia circuit |
US5558083A (en) * | 1993-11-22 | 1996-09-24 | Ohmeda Inc. | Nitric oxide delivery system |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003017837A1 (fr) * | 2001-08-28 | 2003-03-06 | Phase-In Ab | Dispositif d'analyse quantitative de gaz respiratoires |
WO2010030226A1 (fr) * | 2008-09-15 | 2010-03-18 | Phasein Ab | Ligne d'échantillonnage de gaz pour gaz respiratoires |
US9861298B2 (en) | 2008-09-15 | 2018-01-09 | Masimo Corporation | Gas sampling line |
US10952641B2 (en) | 2008-09-15 | 2021-03-23 | Masimo Corporation | Gas sampling line |
US11564593B2 (en) | 2008-09-15 | 2023-01-31 | Masimo Corporation | Gas sampling line |
Also Published As
Publication number | Publication date |
---|---|
AU6872698A (en) | 1998-11-11 |
WO1998046277A3 (fr) | 1999-03-04 |
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