WO1998044329A3 - Rink-chloride linker for solid phase organic synthesis of organic molecules - Google Patents

Rink-chloride linker for solid phase organic synthesis of organic molecules Download PDF

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Publication number
WO1998044329A3
WO1998044329A3 PCT/US1998/005860 US9805860W WO9844329A3 WO 1998044329 A3 WO1998044329 A3 WO 1998044329A3 US 9805860 W US9805860 W US 9805860W WO 9844329 A3 WO9844329 A3 WO 9844329A3
Authority
WO
WIPO (PCT)
Prior art keywords
solid phase
rink
organic synthesis
chloride linker
linker
Prior art date
Application number
PCT/US1998/005860
Other languages
French (fr)
Other versions
WO1998044329A2 (en
Inventor
Ravi S Garigipati
Original Assignee
Smithkline Beecham Corp
Ravi S Garigipati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Ravi S Garigipati filed Critical Smithkline Beecham Corp
Priority to JP54176998A priority Critical patent/JP2001518946A/en
Priority to EP98913115A priority patent/EP0971947A4/en
Priority to CA002285175A priority patent/CA2285175A1/en
Publication of WO1998044329A2 publication Critical patent/WO1998044329A2/en
Publication of WO1998044329A3 publication Critical patent/WO1998044329A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This invention relates to a novel linker for use in solid phase chemistry, its preparation and methods of use of the linker.
PCT/US1998/005860 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules WO1998044329A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP54176998A JP2001518946A (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid-phase organic synthesis of organic molecules
EP98913115A EP0971947A4 (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules
CA002285175A CA2285175A1 (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4469697P 1997-03-28 1997-03-28
US60/044,696 1997-03-28

Publications (2)

Publication Number Publication Date
WO1998044329A2 WO1998044329A2 (en) 1998-10-08
WO1998044329A3 true WO1998044329A3 (en) 1998-12-03

Family

ID=21933821

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/005860 WO1998044329A2 (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules

Country Status (4)

Country Link
EP (1) EP0971947A4 (en)
JP (1) JP2001518946A (en)
CA (1) CA2285175A1 (en)
WO (1) WO1998044329A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0303192A2 (en) 2001-01-12 2003-12-29 Amersham Plc Perfluoro sulfonyl halides and related species as polymer support modifiers

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
US5601992A (en) * 1992-07-21 1997-02-11 Bunsen Rush Laboratories, Inc. Peptide library formats and methods relating thereto
US5684130A (en) * 1995-06-05 1997-11-04 Solid Phase Sciences Corporation Process for synthesis of organic compounds using magnetic particles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546055B1 (en) * 1990-08-31 1996-07-10 Regents Of The University Of Minnesota Polyethylene glycol derivatives for solid-phase applications
JPH05271332A (en) * 1992-03-30 1993-10-19 Nippon Steel Chem Co Ltd Production of amino group-bearing styrene-based polymer
GB9502225D0 (en) * 1995-02-04 1995-03-22 Zeneca Ltd Method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
US5601992A (en) * 1992-07-21 1997-02-11 Bunsen Rush Laboratories, Inc. Peptide library formats and methods relating thereto
US5684130A (en) * 1995-06-05 1997-11-04 Solid Phase Sciences Corporation Process for synthesis of organic compounds using magnetic particles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0971947A4 *

Also Published As

Publication number Publication date
EP0971947A2 (en) 2000-01-19
WO1998044329A2 (en) 1998-10-08
EP0971947A4 (en) 2005-01-26
CA2285175A1 (en) 1998-10-08
JP2001518946A (en) 2001-10-16

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