WO1998044329A3 - Rink-chloride linker for solid phase organic synthesis of organic molecules - Google Patents

Rink-chloride linker for solid phase organic synthesis of organic molecules Download PDF

Info

Publication number
WO1998044329A3
WO1998044329A3 PCT/US1998/005860 US9805860W WO9844329A3 WO 1998044329 A3 WO1998044329 A3 WO 1998044329A3 US 9805860 W US9805860 W US 9805860W WO 9844329 A3 WO9844329 A3 WO 9844329A3
Authority
WO
WIPO (PCT)
Prior art keywords
solid phase
rink
organic synthesis
chloride linker
linker
Prior art date
Application number
PCT/US1998/005860
Other languages
French (fr)
Other versions
WO1998044329A2 (en
Inventor
Ravi S Garigipati
Original Assignee
Smithkline Beecham Corp
Ravi S Garigipati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Ravi S Garigipati filed Critical Smithkline Beecham Corp
Priority to CA002285175A priority Critical patent/CA2285175A1/en
Priority to JP54176998A priority patent/JP2001518946A/en
Priority to EP98913115A priority patent/EP0971947A4/en
Publication of WO1998044329A2 publication Critical patent/WO1998044329A2/en
Publication of WO1998044329A3 publication Critical patent/WO1998044329A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)

Abstract

This invention relates to a novel linker for use in solid phase chemistry, its preparation and methods of use of the linker.
PCT/US1998/005860 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules WO1998044329A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002285175A CA2285175A1 (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules
JP54176998A JP2001518946A (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid-phase organic synthesis of organic molecules
EP98913115A EP0971947A4 (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4469697P 1997-03-28 1997-03-28
US60/044,696 1997-03-28

Publications (2)

Publication Number Publication Date
WO1998044329A2 WO1998044329A2 (en) 1998-10-08
WO1998044329A3 true WO1998044329A3 (en) 1998-12-03

Family

ID=21933821

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/005860 WO1998044329A2 (en) 1997-03-28 1998-03-26 Rink-chloride linker for solid phase organic synthesis of organic molecules

Country Status (4)

Country Link
EP (1) EP0971947A4 (en)
JP (1) JP2001518946A (en)
CA (1) CA2285175A1 (en)
WO (1) WO1998044329A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700524B2 (en) 2001-01-12 2010-04-20 Ge Healthcare Limited Perfluoro sulfonyl halides and related species as polymer support modifiers

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
US5601992A (en) * 1992-07-21 1997-02-11 Bunsen Rush Laboratories, Inc. Peptide library formats and methods relating thereto
US5684130A (en) * 1995-06-05 1997-11-04 Solid Phase Sciences Corporation Process for synthesis of organic compounds using magnetic particles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69130333T2 (en) * 1990-08-31 1999-03-04 Regents Of The University Of Minnesota, Minneapolis, Minn. Resins for solid peptide synthesis
JPH05271332A (en) * 1992-03-30 1993-10-19 Nippon Steel Chem Co Ltd Production of amino group-bearing styrene-based polymer
GB9502225D0 (en) * 1995-02-04 1995-03-22 Zeneca Ltd Method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
US5601992A (en) * 1992-07-21 1997-02-11 Bunsen Rush Laboratories, Inc. Peptide library formats and methods relating thereto
US5684130A (en) * 1995-06-05 1997-11-04 Solid Phase Sciences Corporation Process for synthesis of organic compounds using magnetic particles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0971947A4 *

Also Published As

Publication number Publication date
JP2001518946A (en) 2001-10-16
CA2285175A1 (en) 1998-10-08
EP0971947A4 (en) 2005-01-26
WO1998044329A2 (en) 1998-10-08
EP0971947A2 (en) 2000-01-19

Similar Documents

Publication Publication Date Title
ZA98417B (en) Gas phase polymerization process.
AU2001249423A1 (en) 38692 and 21117, novel dual specificity phosphatase molecules and uses therefor
AUPQ339899A0 (en) Novel molecules
AU2002337660A1 (en) Methods for immobilizing molecules to a solid phase and uses thereof
ZA987554B (en) Methods for the solid phase synthesis of substituted indole compounds.
AU6432800A (en) Process for the synthesis of citalopram
WO1997008190A3 (en) Compounds
WO1999051547A3 (en) Solid phase synthesis of organic compounds via phosphitylating reagents
WO2001000577A3 (en) Preparation of substituted piperidin-4-ones
AU2001268589A1 (en) Cross linked solid supports for solid phase synthesis
AU3664399A (en) Solution phase biopolymer synthesis
AUPP810399A0 (en) Catalytic molecules
AU9344898A (en) Solid phase supports
NO985462L (en) Carbohydrate derivatives and solid phase synthesis thereof
WO1998044329A3 (en) Rink-chloride linker for solid phase organic synthesis of organic molecules
AU1602995A (en) Methods for the solid phase synthesis of glycoconjugates
EP1123108A4 (en) Isolated peptides which bind to hla-b35 molecules
AU2001277728A1 (en) Biphenylcarboxamidoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof
MXPA03002926A (en) Process for the synthesis of 2,2,6,6-tetramethyl-4-oxopiperidine.
CA2258539A1 (en) Ring-fused dihydropyranes, process for the preparation and use thereof
WO2001009065A3 (en) Nitration in a static micromixer
WO1999015542A3 (en) Linker nucleoside, and production and use of the same
WO2002081078A3 (en) Solid phase synthesis supports and methods
AU2866397A (en) Synthesis of 1,1,1-trifluoroethane by fluorination of 1-chloro-1,1-difluoroethane
WO1999053091A3 (en) Dna coding for gdnf, parts of said dna and gdnf variants

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

AK Designated states

Kind code of ref document: A3

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1998913115

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2285175

Country of ref document: CA

Ref country code: CA

Ref document number: 2285175

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 09381990

Country of ref document: US

ENP Entry into the national phase

Ref country code: JP

Ref document number: 1998 541769

Kind code of ref document: A

Format of ref document f/p: F

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWP Wipo information: published in national office

Ref document number: 1998913115

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1998913115

Country of ref document: EP