WO1998042401A1 - Systeme de pompage peristaltique assiste par une depression - Google Patents

Systeme de pompage peristaltique assiste par une depression Download PDF

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Publication number
WO1998042401A1
WO1998042401A1 PCT/US1998/005783 US9805783W WO9842401A1 WO 1998042401 A1 WO1998042401 A1 WO 1998042401A1 US 9805783 W US9805783 W US 9805783W WO 9842401 A1 WO9842401 A1 WO 9842401A1
Authority
WO
WIPO (PCT)
Prior art keywords
housing
pump head
seal surfaces
insert
peristaltic pump
Prior art date
Application number
PCT/US1998/005783
Other languages
English (en)
Inventor
Michael Goldberg
Original Assignee
Michael Goldberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael Goldberg filed Critical Michael Goldberg
Priority to AU65825/98A priority Critical patent/AU6582598A/en
Publication of WO1998042401A1 publication Critical patent/WO1998042401A1/fr

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1253—Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing

Definitions

  • a peristaltic pump comprises a member that compressingly moves along the length of resilient tubing to generate pumping action.
  • Peristaltic tubing pumps are advantageous for sterile and analytical applications because the tubing can be autoclaved and/or replaced with each use, and nothing else contacts the liquid being pumped or dispensed.
  • Classical peristaltic pumps typically rely on the tubing wall resilience and strength to generate the suction developed by the pump. As the tubing ages, its characteristics and pump performance change.
  • a peristaltic pump assembly includes a pump head housing having an interior cavity and tube ports, a pump head disposed within the interior cavity, resilient tubing passing into the pump head housing through one of the tube ports around the pump head and out of the pump head housing through one of the tube ports.
  • the interior cavity is sealed.
  • a vacuum port communicating with the interior cavity allows creation of reduced pressure within the interior cavity around the reduced pressure within the interior cavity around the tubing.
  • the pump head housing may comprise two housing halves which mate along housing seal surfaces to form the interior cavity.
  • the housing halves may be symmetrical shell-like housing halves.
  • the housing seal surfaces may define a housing entry port and a housing exit port through which the tubing passes.
  • There may be a pump head drive mechanism constructed and arranged to drive the pump head.
  • the housing seal surfaces may define a groove, and the pump head housing may further comprise an O-ring or length of O-ring stock fitting snugly within the groove defined by the housing seal surfaces.
  • the pump head housing may include an extended nose and further comprise two fitted elastomeric inserts which fit within a plenum in the extended nose.
  • the elastomeric inserts may mate along insert seal surfaces defining an insert entry port and an insert exit port through which the tubing passes.
  • the elastomeric inserts may clamp ends of the length of O-ring stock or the O-ring between the insert seal surfaces.
  • the elastomeric inserts are typically sized to seal the cavity and to provide an interference fit along the insert seal surfaces, the housing halves, the tubing and the O-ring stock or O-ring.
  • the housing seal surfaces may be entirely covered with a coating of elastomeric material, further covering the housing entry port and the housing exit port, the coating being sufficient to seal the cavity and to provide an interference fit along the tubing.
  • a workbench may support the peristaltic pump and vacuum source.
  • There may be a pump head drive housing with the vacuum source disposed within the pump head drive housing.
  • the pump head housing may include a body enclosing the interior cavity, and a flat cover .
  • the vacuum source may be in a number of locations.
  • It may be part of a laboratory bench, packaged inside the drive mechanism, or packaged separately. It may be a master vacuum system, with vacuum taps at various locations along laboratory benches .
  • Evacuating the pump head housing according to the invention causes ambient atmospheric pressure to exert an expanding force on the inside wall of the tubing. This force is significantly larger than the radial forces in the resilient tubing wall that resist deformation. The wall resilience is thus effectively eliminated as a factor in returning a tubing section to nominal diameter, following compression by the moving pump head.
  • FIG. 1 is an exploded perspective view of a standard peristaltic pump
  • FIG. 2 is an exploded perspective view of a vacuum- assisted peristaltic pump according to the invention, showing connection of the vacuum creating pump to the pump head housing;
  • FIG. 3 is a perspective view of a pump head housing half modified to seal the pump head housing from the atmosphere;
  • FIG. 4 is a schematic plan view showing the pump head housing half of Fig. 3, including the tubing, O-ring stock, and elastomeric inserts; and
  • FIG. 5 is a schematic end view showing two pump head housing halves assembled together.
  • a standard peristaltic pump includes a pump head drive mechanism 10 which drives a pump rotor 12.
  • the pump rotor 12 is enclosed within a cavity in a pump head housing which is formed from two symmetrical shell-like halves 14, or a body and flat cover.
  • the housing halves 14 mate along housing seal surfaces 15.
  • Tubing 16 enters the pump head housing through housing entry port 18, loops around the pump rotor 12, and exits the pump head housing through housing exit port 20.
  • the region of the pump head housing containing the housing entry port 18 and housing exit port 20 is referred to generally as the housing nose 22.
  • the tubing 16 is occluded to provide the pumping action by being pinched between rollers 24 and pump head housing cavity surface 26. Screws, or other suitable fasteners 28 fasten the housing halves 14 together to form the pump head housing and to secure the pump head housing to the pump head drive mechanism 10.
  • a vacuum pump 30 evacuates the cavity inside the pump head housing outside the tubing through vacuum port 32 in one of the housing halves 14.
  • the location of the vacuum port is not critical.
  • the port should not be periodically or continuously occluded by the tubing, and if located so as to emerge radially from the housing circumference (as shown in broken lines 32') / will permit stacking of multiple pump heads.
  • Vacuum pump 30 preferably generates a pressure drop of at least 25 inches of mercury within the cavity.
  • Pressure regulator 34 in vacuum line 36 between vacuum pump 30 and the pump head housing reduces the pressure drop to between 20 and 25 inches of mercury.
  • vacuum pump 30 may operate intermittently to maintain this pressure drop, if a suitable accumulator is provided in the vacuum circuit, or may be throttled by a suitable automatic speed control .
  • Vacuum pump 30 may be located on the same laboratory bench 31 supporting the peristaltic pump. Alteratively, it may be located within the housing of the pump head drive mechanism 10 or packaged as a separate item for use with existing motor drives.
  • Sealing the housing helps maintain the desired pressure drop within the pump head housing cavity. Perfect seals are not required for good performance, provided the desired vacuum is maintained. Better seals allow the use of a lower volumetric capacity vacuum source.
  • a simple vibrator pump provides ample vacuum.
  • FIG. 3 is a perspective view of a pump head housing half modified to seal the pump head housing from the atmosphere;
  • FIG. 4 is a schematic plan view generally showing the pump head housing half of FIG. 3, including the tubing, O-ring stock and elastomeric inserts, and
  • FIG. 5 is a schematic end view generally showing two pump head housing halves assembled together.
  • the housing halves 14 are modified from the standard housing halves shown in FIG. 1 by extending the nose 22.
  • the housing entry port 18 and exit port 20 are not extended; rather, the extended nose 22 is left vacant so as to form a plenum 38 accommodating two elastomeric inserts 40.
  • Inserts 40 mate along insert seal surfaces 42.
  • a length of O-ring stock 44 fits snugly within a groove (not shown) formed by the housing seal surfaces 15.
  • the ends 46 of the O-ring stock extend between the elastomeric inserts 40 such that, when the halves are assembled, the ends 46 of the O-ring stock are clamped between the insert seal surfaces 42.
  • an O-ring may be placed in a suitable groove in either half, or in a cover member. In this embodiment, the O-ring passes between the cover member (or housing half) and the outside surface of insert half nearest the cover member.
  • the insert may or may not have a groove to accommodate the O-ring. The particular path of the O-ring is not critical, provided a good seal is maintained.
  • the insert seal surfaces 42 define an insert entry port 48 and an insert exit port 50 through which tubing 16 enters and exits the pump head housing.
  • the elastomeric inserts 40 are preferably sized to provide an interference fit along the insert seal surfaces 42, the housing halves
  • the standard housing halves 14 as shown in FIG. 1 may be coated along the entire mating surfaces 15, including the housing entry port 18 and the housing exit port 20, with a coating of a suitable elastomer sufficient to seal the cavity and provide an interference fit along tubing 16.
  • New 3/8" Norprene tubing has a calibration factor, or displacement, (referred to by the industry as the "calfactor") of about 3.8 ml/revolution in a Masterflex Model 7016 pump head.
  • calfactor calibration factor
  • this calfactor is maintained over a very wide speed range. Under vacuum, in a test pump head, the same tubing exhibited negligible calfactor deviation over a speed range of 100 to 600 rpm. This advantageous property allows calibration at a nominal speed and considerable freedom to change speed without recalibration.
  • the vacuum source is preferably independent of the pump head itself.
  • the pump is subject to repeated stops and starts, and frequently delivers volumes requiring fractions of a revolution, at a variety of speeds.
  • a vacuum source coupled to the same mechanical drive as the pump head may not work satisfactorily in some applications.
  • a significant change in vacuum can result in a corresponding change in calfactor. Intermittent operation with periods of idle time can result in large vacuum fluctuations, and possible loss of vacuum altogether.
  • the vacuum is thus preferably regulated to an accuracy commensurate with the application accuracy requirements, preferably with an independent, controlled vacuum source.
  • This vacuum source may be integrated with the drive mechanism housing to provide a complete packaged product, but is preferably powered by a motor, or the like, that is independent from that of the vacuum assisted pump head.
  • vacuum may be provided by an additional peristaltic pump of standard design, attached to, and driven by, the same drive mechanism. Suitable vacuum regulation is desirable, and a suitable accumulator is recommended.
  • the peristaltic pump of the invention may use features found in a Masterflex peristaltic pump. These and other features are described in U.S. Patent No. 3,358,609 (Worth et al . ) now expired.
  • the Masterflex has a closed shell design that may be sealed to the atmosphere and evacuated with reasonable modifications, as in the embodiments of the invention described above.
  • An exemplary embodiment comprises a housing body, with a flat cover member .

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Reciprocating Pumps (AREA)

Abstract

L'invention porte sur une pompe péristaltique comportant un boîtier (14) de tête de pompe présentant une cavité intérieure fermée et un orifice d'aspiration (32) communiquant avec ladite cavité pour y produire un vide partiel. Un rotor (12) de tête de pompe monté dans la cavité est mu par le mécanisme (10) d'entraînement de la tête de pompe. Un tube élastique (16) traverse le boîtier (14), forme une boucle autour du rotor (12) de tête de pompe, puis sort du boîtier (14).
PCT/US1998/005783 1997-03-24 1998-03-24 Systeme de pompage peristaltique assiste par une depression WO1998042401A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU65825/98A AU6582598A (en) 1997-03-24 1998-03-24 Vacuum assisted peristaltic pumping

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82267997A 1997-03-24 1997-03-24
US08/822,679 1997-03-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US08/821,818 Continuation-In-Part US6146877A (en) 1997-03-21 1997-03-21 Identification of the progression elevated gene-3 and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/052,753 Continuation-In-Part US6472520B2 (en) 1997-03-21 1998-03-31 Rat PEG-3 promoter

Publications (1)

Publication Number Publication Date
WO1998042401A1 true WO1998042401A1 (fr) 1998-10-01

Family

ID=25236677

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/005783 WO1998042401A1 (fr) 1997-03-24 1998-03-24 Systeme de pompage peristaltique assiste par une depression

Country Status (2)

Country Link
AU (1) AU6582598A (fr)
WO (1) WO1998042401A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1538335A2 (fr) * 2003-12-05 2005-06-08 Crane Process Flow Technologies GmbH Pompe péristaltique avec un dispositif générateur de vide
WO2020181488A1 (fr) * 2019-03-12 2020-09-17 璞真生活有限公司 Pompe péristaltique et instrument de soins infirmiers
US11103043B2 (en) 2019-02-14 2021-08-31 Puzhen Life Co., Limited Care instrument

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759017A (en) * 1996-01-31 1998-06-02 Medtronic Electromedics, Inc. Peristaltic pump and tube loading system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759017A (en) * 1996-01-31 1998-06-02 Medtronic Electromedics, Inc. Peristaltic pump and tube loading system

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1538335A2 (fr) * 2003-12-05 2005-06-08 Crane Process Flow Technologies GmbH Pompe péristaltique avec un dispositif générateur de vide
EP1538335A3 (fr) * 2003-12-05 2006-01-11 Crane Process Flow Technologies GmbH Pompe péristaltique avec un dispositif générateur de vide
US11103043B2 (en) 2019-02-14 2021-08-31 Puzhen Life Co., Limited Care instrument
US11484108B2 (en) 2019-02-14 2022-11-01 Puzhen Life Co., Limited Care instrument
WO2020181488A1 (fr) * 2019-03-12 2020-09-17 璞真生活有限公司 Pompe péristaltique et instrument de soins infirmiers

Also Published As

Publication number Publication date
AU6582598A (en) 1998-10-20

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