WO1998031793A3 - Immunomodulating properties, amino acid and nucleotide sequence of colostrum derived growth factor - Google Patents

Immunomodulating properties, amino acid and nucleotide sequence of colostrum derived growth factor Download PDF

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Publication number
WO1998031793A3
WO1998031793A3 PCT/GB1998/000063 GB9800063W WO9831793A3 WO 1998031793 A3 WO1998031793 A3 WO 1998031793A3 GB 9800063 W GB9800063 W GB 9800063W WO 9831793 A3 WO9831793 A3 WO 9831793A3
Authority
WO
WIPO (PCT)
Prior art keywords
amino acid
growth factor
derived growth
nucleotide sequence
immunomodulating properties
Prior art date
Application number
PCT/GB1998/000063
Other languages
French (fr)
Other versions
WO1998031793A2 (en
Inventor
Denise Kelly
Original Assignee
Rowett Research Inst
Denise Kelly
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700730.6A external-priority patent/GB9700730D0/en
Priority claimed from GBGB9700871.8A external-priority patent/GB9700871D0/en
Priority claimed from GBGB9701179.5A external-priority patent/GB9701179D0/en
Priority claimed from GBGB9701325.4A external-priority patent/GB9701325D0/en
Application filed by Rowett Research Inst, Denise Kelly filed Critical Rowett Research Inst
Priority to AU54929/98A priority Critical patent/AU5492998A/en
Publication of WO1998031793A2 publication Critical patent/WO1998031793A2/en
Publication of WO1998031793A3 publication Critical patent/WO1998031793A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

There is provided a partial amino acid sequence for the 3' end of porcine colostrum derived growth factor as set out in SEQ ID NO 1. The polynucleotide sequence encoding for that portion of CDGF is also provided and is set out in SEQ ID NO 2. Further, the immunomodulating properties of CDGF have been investigated. It has been found that CDGF is able to stimulate cell proliferation and differentiation and is also able to regulate inflammatory responses.
PCT/GB1998/000063 1997-01-15 1998-01-15 Immunomodulating properties, amino acid and nucleotide sequence of colostrum derived growth factor WO1998031793A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU54929/98A AU5492998A (en) 1997-01-15 1998-01-15 Immunomodulating properties, amino acid and nucleotide sequence of colostrum derived growth factor

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB9700730.6 1997-01-15
GBGB9700730.6A GB9700730D0 (en) 1997-01-15 1997-01-15 Sequence
GB9700871.8 1997-01-16
GBGB9700871.8A GB9700871D0 (en) 1997-01-16 1997-01-16 Sequence
GBGB9701179.5A GB9701179D0 (en) 1997-01-21 1997-01-21 Sequence
GB9701179.5 1997-01-21
GBGB9701325.4A GB9701325D0 (en) 1997-01-23 1997-01-23 Sequence
GB9701325.4 1997-01-23

Publications (2)

Publication Number Publication Date
WO1998031793A2 WO1998031793A2 (en) 1998-07-23
WO1998031793A3 true WO1998031793A3 (en) 1998-10-22

Family

ID=27451592

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1998/000063 WO1998031793A2 (en) 1997-01-15 1998-01-15 Immunomodulating properties, amino acid and nucleotide sequence of colostrum derived growth factor

Country Status (2)

Country Link
AU (1) AU5492998A (en)
WO (1) WO1998031793A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0527283A1 (en) * 1991-08-12 1993-02-17 Societe Des Produits Nestle S.A. Food composition
WO1997004009A1 (en) * 1995-07-15 1997-02-06 The Rowett Research Institute Colostrum derived growth factor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0527283A1 (en) * 1991-08-12 1993-02-17 Societe Des Produits Nestle S.A. Food composition
WO1997004009A1 (en) * 1995-07-15 1997-02-06 The Rowett Research Institute Colostrum derived growth factor

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HOSTOMSKY, Z. ET AL.: "Solid-phase assembly of cow colostrum trypsin inhibitor gene", NUCLEIC ACIDS RESEARCH, vol. 15, no. 12, 1987, pages 4849 - 4856, XP002073966 *
SHING, Y. ET AL.: "Purification of polypeptide growth factors from milk", METHODS IN ENZYMOLOGY, vol. 146, 1987, pages 42 - 48, XP002073968 *
SWISSPROT DATABASE; SWISSPROT:IBPC_BOVIN; ACCESSION-NO: P00976, 21 July 1986 (1986-07-21), XP002073967 *

Also Published As

Publication number Publication date
WO1998031793A2 (en) 1998-07-23
AU5492998A (en) 1998-08-07

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