WO1998014547A2

WO1998014547A2 - Surface cleaning agent

Info

Publication number: WO1998014547A2
Application number: PCT/EP1997/005184
Authority: WO
Inventors: Siegfried Bragulla; Karl-Heinz Maurer; Andreas Potthoff; Wilfried Serve
Original assignee: Henkel-Ecolab Gmbh & Co. Ohg
Priority date: 1996-09-30
Filing date: 1997-09-22
Publication date: 1998-04-09
Also published as: JP2001501244A; DE19640201A1; PL332322A1; NZ334912A; EP0929641A2; WO1998014547A3; CA2267331A1; AU719542B2; AU4460597A

Abstract

The object of the invention is to improve agents for cleaning surfaces soiled with protein and/or fat, in particular with respect to the effect of these agents on deposits of milk and milk products. To that end, at least one protease and/or at least one lipase as enzyme(s), and at least one surfactant component and at least one acid component are used.

Description

"Means for cleaning surfaces"

The invention relates to an agent for cleaning surfaces contaminated by milk or milk products and to the use thereof.

On surfaces of containers, pipes and processing equipment that come into contact with milk or milk products during milk production and further processing, deposits containing protein and fat residues are formed with a physiologically high proportion of calcium, which are very difficult to remove. Milking machines, farm tanks, milk collection vehicles, tanks, pipelines, heaters and other equipment required for milk production and processing are particularly affected.

In the prior art, two cleaning strategies were essentially followed to remove the deposits. On the one hand, strongly alkaline and strongly acidic cleaning agents were used alternately to clean the surfaces contaminated with milk deposits. The use of strongly alkaline cleaning agents serves to remove the protein-containing deposits. Due to the alkalinity of the cleaning agent solution as well as the phenomenon of the intrinsic "water hardness", combined with a calcium content in the dirt residues, there are the characteristic precipitations of especially poorly soluble calcium salts. These precipitations can then only be removed with acidic cleaners, which is why an alternating procedure is required.

On the other hand, alkaline cleaners are used that contain complexing agents to stabilize the water hardness. These alkaline "single-phase cleaners" - those cleaners that do not require the additional use of acidic products Remove residues from dairy products - are less preferred from an environmental point of view because they contain complexing agents.

In summary, it can be stated that the use of alkaline cleaners in the removal of protein-containing dirt residues, such as dairy products, is necessary according to the prior art known to date. The use of alkali cleaners either entails an additional cleaning step (cleaning with the aid of acid cleaners) or the addition of the less preferred complexing agents.

It is therefore the object of the present invention to provide a cleaning agent composition which effectively removes protein and fat-containing deposits on surfaces which occur during milk production and further processing, without either the use of complexing agents or an additional or several additional cleaning steps with others Detergent compositions are required, the effectiveness of the detergents according to the invention in cleaning the contaminated surfaces being at least comparable to that of detergent compositions known in the prior art.

According to the invention, on the one hand, a means is provided for cleaning surfaces contaminated by milk or milk products, which contains at least one protease and / or at least one lipase as enzyme (s), at least one surfactant component and at least one acid component.

According to a preferred embodiment, anionic, cationic, amphoteric or non-ionic surfactants or any mixtures of these classes of surfactants can be used as the surfactant component. Compounds such as fatty alcohol polyglycol ethers, fatty acid amides, fatty acid ethoxylates and fatty acid esters of polyols, in particular sugars (glucose), fatty alcohol alkoxylates with EO / PO or their commercially available mixtures are preferred as nonionic surfactants.

According to a preferred embodiment, the aspartic proteases are used as acid proteases to remove the protein residues from among the proteases. They have a catalytic optimum in the acidic pH range, since the protonation of a catalytically active aspartate residue in the active center of the enzyme is necessary.

Among the aspartate proteases, enzymes of animal, fungal and bacterial origin are suitable for removing the residues (EC 3.4.23 ...). Particularly noteworthy are pepsin, gastriesin, rennin or chymosin of animal origin, penicillopepsin of bacterial origin and aspartic proteases from various fungi, in particular from Mucor spp., Aspergillus niger, Rhizopus spp. and Endothia parasitica.

If acidic proteases are used in a mixture, the ratio of pepsin to protease is 10: 1 to 1:10, preferably 5: 1 to 1: 5.

Among the lipases in particular those are used which have a pH optimum in the acidic range. Particularly preferred examples are lipases from fungi, especially from Humicola insolens.

According to a preferred embodiment, the pH of the application solution is adjusted to 0.5 to 4.0, the range between 1.5 and 3.5 being particularly preferred. The pH of the application solution can be adjusted by using conventional pH buffer mixtures. All commercially available, organic and inorganic acids such as nitric acid, phosphoric acid, citric acid, lactic acid, acetic acid, Methanesulfonic acid, formic acid, amidosulfonic acid are used. However, the application solution should preferably be free of phosphates and nitrates.

According to a preferred embodiment, additives are added to the acidic cleaning agent to remove milk stains, one or more disinfectants and / or one or more antifoams and / or one or more enzyme stabilizers being used.

Particularly preferred disinfectants from the class of cationic surfactants are, in particular, their straight-chain or cyclic C ₈ -C ₁₈ tetraalkylammonium compounds, C ₈ -C ₁₈ benzalkonium chlorides, quaternary C ₈ -C ₁₈ alkylphosphonium salts. Particularly preferred disinfectants from the class of amphoteric surfactants are, for example, C ₈ -C ₁₈ fatty acid amine derivatives with betaine structure, in particular glycine derivatives and

Cocoalkyldimethylammonium betaine. Particularly preferred disinfectants from the class of anion-active substances, such as Alk3240688, ether carboxylic acids from DE-A-4225626 and from the class of anion-active surfactants, are those which consist of aromatic sulfonic acids, alkylsulfonic acids, alkyl ether sulfonic acids, fatty alcohol sulfuric acid esters and sulfonated fatty acids (eg alkylbenzenesulfonic acid, dodecylbenzonic acid, dodecylbenzonic acid, dodecylbenzonic acid, dodecylbenzonic acid, dodecylbenzonic acid, dodecylbenzonic acid, dodecylbenzonic acid, dodecylbenzonic acid, , Alkanesulfonic acids) are produced. As an anti-foaming agent C can _12- ₆ ι -Fettalkoholalkylate, Fettalkoholblockpolymerisate EO / PO, C _12-16 fatty alcohol-EO / PO adducts, and C _12-16 - fatty alcohol polyglycol ethers are used alone or as mixtures. If necessary, customary enzyme stabilizers such as glycols (for example 1, 2-propanediol), borate salts and / or carboxylic acids can be added to the enzyme mixtures.

Disinfectants, anti-foaming agents and enzyme stabilizers are used in the usual, known concentrations. According to a preferred embodiment, the total concentration of enzyme (s), surfactant (s), acid (s) and additives) in the application solution is 0.5 to 10% by weight, preferably 1 to 5% by weight.

According to a preferred embodiment, a weight ratio of the enzyme to the surfactant component (s) is between 1: 10000 and 1:10, preferably between 1: 10000 and 1: 1000, and a weight ratio of the enzyme and surfactant component (s) (to) the acid component (s) between 1: 1 and 1:99, preferably between 1: 5 and 1:50.

According to a preferred embodiment, a weight ratio of the enzyme, surfactant and acid components to the additive (s) is chosen between 10:90 and 90:10, preferably between 20:80 and 80:20.

According to a preferred embodiment, the cleaning agent according to the invention is packaged in liquid form as an aqueous solution, in semi-solid form as a paste, in solid form as a tablet or in powder form. A powder or tablet product is preferred for reasons of active substance concentration, and a liquid product is preferred for reasons of more convenient handling.

If the acidic cleaner is a powder or tablet product, this is preferably composed of about 20 to about 80% by weight of an organic or inorganic substance which is acidic when dissolved in water, about 0.1 to about 5% by weight. non-ionic surfactants, about 0.1 to about 10% by weight, preferably about 0.1 to 5% by weight, of one or more microbicidal compounds from groups b1) to b4), the rest being 100% by weight, for example Sodium sulfate and / or other active ingredients or auxiliaries can exist. Since the cleaner is supposed to be a powder product, The organic or inorganic substance that reacts acidically when dissolved in water must be a solid. Examples of such inorganic substances are acidic salts such as dihydrogen phosphates or hydrogen sulfates. Organic substances that can be used are, for example, carboxylic acids such as tartaric acid or citric acid or, for example, sulfonic acids such as amidosulfonic acid. Addition products of ethylene oxide and / or propylene oxide onto fatty alcohols, fatty amines or fatty acids with 12 to 18 carbon atoms in the alkyl radical or fatty acid esters of polyols, in particular of sugars such as glucose, are preferably chosen as nonionic surfactants. Addition products of ethylene oxide and / or propylene oxide onto fatty alcohols are particularly preferred. Examples of such addition products are addition products of on average 8 or on average 6 ethylene oxide units on fatty alcohol mixtures with 12 to 18 carbon atoms in the alkyl radical. Further examples are adducts of ethylene oxide and propylene oxide with such fatty alcohols, for example an adduct of 5 moles of ethylene oxide and 4 moles of propylene oxide with a fatty alcohol mixture having 12 to 14 carbon atoms in the alkyl radical. Another nonionic surfactant that can be used is an adduct of 5 moles of ethylene oxide with oleyl alcohol.

If it is desired to package the acidic cleaner as a liquid product, it is preferably composed of about 20 to about 80% by weight of phosphoric acid, formic acid, acetic acid, glycolic acid, lactic acid, citric acid and / or methanesulfonic acid as such, as a solution in one another or in the form an aqueous solution having an acid content of at least 5% by weight, about 0.1 to about 5% by weight of nonionic surfactants as described above, about 0.1 to about 10% by weight, preferably about 0.1 to about 5% by weight of one or more microbicidal compounds from groups b1) to b4), the remainder being 100% by weight of water or an aqueous solution of further active ingredients or auxiliaries. Liquid acids can be used individually or as a mixture with one another. Solid acids like for example, citric acid can be present in another liquid acid or dissolved in water. If acids are used as an aqueous solution, they should have an acid content of at least 5% by weight in order to achieve a sufficient acid concentration in the dilute application solution. If, for reasons of environmental protection, it is desired to use a phosphate-free acidic cleaner, this preferably contains a combination of several of the organic acids mentioned. Examples of these are mixtures of methanesulfonic acid, citric acid and formic acid, acetic acid, lactic acid and citric acid, acetic acid, glycolic acid and methanesulfonic acid and further combinations. If necessary, so much water is added to these acid combinations that a clear solution is formed.

According to a preferred embodiment, the compound is provided as a compact cleaning agent with all components or as a set of complementary partial formulations, each with one or more components. A combination of separate sub-formulations is possible especially for liquid products.

According to the invention, the use of the agents according to the invention for cleaning surfaces contaminated by milk or milk products is claimed.

According to a preferred embodiment, the use of the ready-made cleaning agent according to the invention as an application solution is carried out at temperatures between 20 ° and 70 ° C., preferably between 40 ° and 60 ° C. EXAMPLES

As general test conditions for the execution of the four examples described below, the following information must be taken into account: The cleaning was carried out in a diving apparatus with hydraulic mechanics. A temperature of 40 ° C was selected during the cleaning process. The water had a hardness of 16 ° d. The cleaning process took 15 minutes. A) condensed milk and b) milk stone (designated in the description of the results as (a) and (b)) served as soiling for the tests. The percentage result results relate to the degree of dirt removal after cleaning compared to standard soiling before cleaning. The results were determined by gravimetric measurements.

The cleaning effect of various enzyme-containing formulations was tested in comparison to alkaline, complexing agent-containing standard formulations and acidic standard cleaners.

Comparative Example 1

Alkaline, "single-phase" standard cleaner (concentration of 0.5%), all figures are percentages by weight and relate to the entire agent.

The cleaner had the following composition:

30% KOH, 20% EDTA, 3% anti-foaming agent and distilled water.

A cleaning performance of 99.5% was achieved under test conditions (a), and a cleaning performance of 91% was achieved under test conditions (b). Comparative Example 2

Comparative formulation of an acidic standard cleaner (concentration of

0.5%)

The cleaner had the following composition:

30% H ₃ PO ₄ , 3% non-ionic surfactants, 10% H ₂ SO ₄ and distilled water.

A cleaning performance of 62% was achieved under test conditions (a), and a cleaning performance of 41% was achieved under test conditions (b).

Example 1 according to the invention

Formulation of an acidic, enzyme-containing cleaner according to the invention in powder form (use concentration of 0.5%)

The cleaner had the following composition:

40% amidosulfonic acid, 10% citric acid, 3% non-ionic surfactants, 1% pepsin, 2% acidic protease, acidic protease in this context is protease NWG

(Amano), protease A (Amano) from fungi (e.g. Aspergillus niger), 1% lipase and the rest sodium sulfate.

A cleaning performance of 99.5% was achieved under test conditions (a), and a cleaning performance of 98% was achieved under test conditions (b).

Example 2 according to the invention

Recipe of an acidic, enzyme-containing cleaning agent combination of two components (A) and (B) in liquid form (use concentration of 0.5%, namely 0.25% per component)

The detergent components had the following compositions: (A) 30% formic acid, 10% citric acid, 3% non-ionic surfactants (here: ethoxylated fatty alcohols) and distilled water.

(B) 5% pepsin, 10% acidic protease (here: protease NWG (Amano) or protease A (Amano) from fungi (eg Aspergillus nieger)), 2% lipase, 40% propylene glycol and distilled water.

A cleaning performance of 99% was achieved under test conditions (a), and a cleaning performance of 98.5% was achieved under test conditions (b).

Comparison of Examples 1 and 2, which are based on cleaning with agents according to the known prior art, with the cleaning performance of the acidic, enzyme-containing agents according to the invention (Examples 3 and 4) shows that the compositions according to the invention have an at least comparable (with Example 1) or even superior (compared to Example 2) effectiveness in removing milk or milk product stains.

Claims

PATENT CLAIMS

1. Means for cleaning surfaces contaminated by protein and / or greasy soils, characterized in that at least one protease and / or at least one lipase is used as the enzyme (s), at least one surfactant component and at least one acid component.

2. Composition according to claim 1, characterized in that the protease (s) is (are) selected from the class of acidic proteases, in particular aspartate proteases.

3. Composition according to claim 1 or 2, characterized in that the pH of the application solution is between 0.5 and 4.0, preferably between 1, 5 and 3.5.

4. Agent according to one of the preceding claims, characterized in that one or more disinfectants and / or one or more anti-foaming agents and / or one or more enzyme stabilizers are contained as additives.

5. Agent according to one of the preceding claims, characterized in that the total concentration of enzyme (s), surfactant (s), acid (s) and additives) in the application solution 0.5 to 10 wt .-%, preferably 1 to 5 % By weight.

6. Composition according to one of the preceding claims, characterized in that a weight ratio of the enzyme to (the) surfactant component (s) between 1: 10000 and 1:10, preferably between 1: 10000 and 1: 1000, and a weight ratio of Enzyme and surfactant component (s) for the component (s) between 1: 1 and 1:99, preferably between 1: 5 and 1:50.

7. Composition according to one of the preceding claims, characterized in that a weight ratio of the enzyme, surfactant and acid components to the additive (s) between 10:90 and 90:10, preferably between 20:80 and 80:20 is chosen.

8. Composition according to one of the preceding claims, characterized in that it is made up in liquid form as an aqueous solution, in semi-solid form as a paste, in solid form as a tablet or in powder form.

9. Agent according to one of the preceding claims, characterized in that the compound is provided as a compact cleaning agent with all components or as a set of complementary partial formulations, each with one or more components.

10. Use of an agent according to one of the preceding claims, characterized in that it is used for cleaning surfaces contaminated with milk or milk products.

11. Embodiment according to claim 10, characterized in that the compound is used as an application solution at temperatures between 20 ° and 70 ° C, preferably between 40 ° and 60 ° C.