WO1998010078A3 - Cloning of full-length human pex cdna - Google Patents
Cloning of full-length human pex cdna Download PDFInfo
- Publication number
- WO1998010078A3 WO1998010078A3 PCT/CA1997/000617 CA9700617W WO9810078A3 WO 1998010078 A3 WO1998010078 A3 WO 1998010078A3 CA 9700617 W CA9700617 W CA 9700617W WO 9810078 A3 WO9810078 A3 WO 9810078A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pex
- renal failure
- chronic renal
- hyperphosphatemia
- cloning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU41073/97A AU4107397A (en) | 1996-09-05 | 1997-09-04 | Cloning of full-length human pex cdna |
CA002264955A CA2264955A1 (en) | 1996-09-05 | 1997-09-04 | Cloning of full-length human pex cdna |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2545496P | 1996-09-05 | 1996-09-05 | |
US60/025,454 | 1996-09-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998010078A2 WO1998010078A2 (en) | 1998-03-12 |
WO1998010078A3 true WO1998010078A3 (en) | 1998-07-09 |
Family
ID=21826161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CA1997/000617 WO1998010078A2 (en) | 1996-09-05 | 1997-09-04 | CLONING OF FULL-LENGTH HUMAN PEX cDNA |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU4107397A (en) |
CA (1) | CA2264955A1 (en) |
WO (1) | WO1998010078A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2245903A1 (en) | 1998-09-28 | 2000-03-28 | Mcgill University | Use of pex in the treatment of metabolic bone diseases |
AU2004222823B2 (en) * | 1999-02-24 | 2006-11-30 | Enobia Pharma Inc. | Composition, Methods and Reagents for the Synthesis of a Soluble Form of Human PHEX |
CA2262056A1 (en) | 1999-02-24 | 2000-08-24 | Guy Boileau | Composition, methods and reagents for the synthesis of a soluble form of human pex |
US20030175808A1 (en) * | 2000-06-21 | 2003-09-18 | Tomofumi Kurokawa | Novel protein and dna thereof |
JP2004506046A (en) * | 2000-08-23 | 2004-02-26 | バイオメップ インコーポレイティド | Methods and compositions for promoting bone formation |
AU2884102A (en) | 2000-12-07 | 2002-06-18 | Sangamo Biosciences Inc | Regulation of angiogenesis with zinc finger proteins |
US7067317B2 (en) | 2000-12-07 | 2006-06-27 | Sangamo Biosciences, Inc. | Regulation of angiogenesis with zinc finger proteins |
-
1997
- 1997-09-04 CA CA002264955A patent/CA2264955A1/en not_active Abandoned
- 1997-09-04 WO PCT/CA1997/000617 patent/WO1998010078A2/en active Application Filing
- 1997-09-04 AU AU41073/97A patent/AU4107397A/en not_active Abandoned
Non-Patent Citations (5)
Title |
---|
ANONYMOUS: "A gene ( PEX ) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium.", NATURE GENETICS, vol. 11, no. 2, October 1995 (1995-10-01), pages 130 - 136, XP002056683 * |
DATABASE EMBL 21 January 1997 (1997-01-21), LIPMAN M.L. ET AL.: "Human metalloendopeptidase analog (PEX) mRNA, complete sequence.", XP002056687 * |
DU L. ET AL.: "cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone.", GENOMICS, vol. 36, no. 1, 15 August 1996 (1996-08-15), pages 22 - 28, XP002056685 * |
NELSON A. E. ET AL.: "The PEX gene: not a simple answer for X-linked hypophosphataemic rickets and oncogenic osteomalacia.", MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 132, no. 1-2, 19 September 1997 (1997-09-19), pages 1 - 5, XP002056686 * |
ROWE P. S.: "Molecular biology of hypophosphatemics rickets and oncogenic osteomalacia.", HUMAN GENETICS, vol. 94, no. 5, November 1994 (1994-11-01), pages 457 - 467, XP002056684 * |
Also Published As
Publication number | Publication date |
---|---|
WO1998010078A2 (en) | 1998-03-12 |
AU4107397A (en) | 1998-03-26 |
CA2264955A1 (en) | 1998-03-12 |
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