WO1998006851A3 - DEFINING EPITOPES OF THE OUTER MEMBRANE PROTEIN CopB OF $i(MORAXELLA CATARRHALIS) - Google Patents
DEFINING EPITOPES OF THE OUTER MEMBRANE PROTEIN CopB OF $i(MORAXELLA CATARRHALIS) Download PDFInfo
- Publication number
- WO1998006851A3 WO1998006851A3 PCT/US1997/014221 US9714221W WO9806851A3 WO 1998006851 A3 WO1998006851 A3 WO 1998006851A3 US 9714221 W US9714221 W US 9714221W WO 9806851 A3 WO9806851 A3 WO 9806851A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- copb
- reactivity
- membrane protein
- outer membrane
- moraxella catarrhalis
- Prior art date
Links
- 101150036540 Copb1 gene Proteins 0.000 title abstract 4
- 241000588655 Moraxella catarrhalis Species 0.000 title abstract 2
- 101710116435 Outer membrane protein Proteins 0.000 title abstract 2
- 230000009257 reactivity Effects 0.000 abstract 4
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 229940024606 amino acid Drugs 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229960001230 asparagine Drugs 0.000 abstract 1
- 235000009582 asparagine Nutrition 0.000 abstract 1
- 125000000613 asparagine group Chemical group N[C@@H](CC(N)=O)C(=O)* 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 230000001759 immunoprophylactic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002262748A CA2262748A1 (en) | 1996-08-12 | 1997-08-12 | Defining epitopes of the outer membrane protein copb of moraxella catarrhalis |
AU41500/97A AU740481B2 (en) | 1996-08-12 | 1997-08-12 | Defining epitopes of the outer membrane protein CopB of moraxella catarrhalis |
EP97939404A EP0920513A2 (en) | 1996-08-12 | 1997-08-12 | DEFINING EPITOPES OF THE OUTER MEMBRANE PROTEIN CopB OF MORAXELLA CATARRHALIS |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2383296P | 1996-08-12 | 1996-08-12 | |
US60/023,832 | 1996-08-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998006851A2 WO1998006851A2 (en) | 1998-02-19 |
WO1998006851A3 true WO1998006851A3 (en) | 1998-05-07 |
Family
ID=21817463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/014221 WO1998006851A2 (en) | 1996-08-12 | 1997-08-12 | DEFINING EPITOPES OF THE OUTER MEMBRANE PROTEIN CopB OF $i(MORAXELLA CATARRHALIS) |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0920513A2 (en) |
AU (1) | AU740481B2 (en) |
CA (1) | CA2262748A1 (en) |
WO (1) | WO1998006851A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU740956B2 (en) * | 1997-07-21 | 2001-11-15 | Baxter Healthcare Sa | Modified immunogenic pneumolysin compositions as vaccines |
US6627728B1 (en) | 1998-05-12 | 2003-09-30 | Smithkline Beecham Biologicals S.A. | Compounds from moraxella catarrhalis |
GB9810285D0 (en) | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
ES2306662T3 (en) * | 1999-05-24 | 2008-11-16 | Glaxosmithkline Biologicals S.A. | NEW COMPOUNDS OF MORAXELLA CATARRHALIS. |
GB9915031D0 (en) * | 1999-06-25 | 1999-08-25 | Smithkline Beecham Biolog | Novel compounds |
ATE368686T1 (en) * | 1999-09-14 | 2007-08-15 | Glaxosmithkline Biolog Sa | POLYPEPTIDES FROM MORAXELLA (BRANHAMELLA) CATARRHALIS |
CN1745096A (en) * | 2003-01-30 | 2006-03-08 | 惠氏控股公司 | Cross-protective epitopes of moraxella catarrhalis and use thereof |
CN111675753A (en) * | 2020-05-19 | 2020-09-18 | 深圳市疾病预防控制中心 | Avian influenza virus epitope screening method and application |
-
1997
- 1997-08-12 CA CA002262748A patent/CA2262748A1/en not_active Abandoned
- 1997-08-12 AU AU41500/97A patent/AU740481B2/en not_active Ceased
- 1997-08-12 EP EP97939404A patent/EP0920513A2/en not_active Withdrawn
- 1997-08-12 WO PCT/US1997/014221 patent/WO1998006851A2/en not_active Application Discontinuation
Non-Patent Citations (3)
Title |
---|
AEBI C ET AL: "Moraxella catarrhalis outer membrane protein CopB: Identification of a peptide that contains a protective epitope.", 36TH ICAAC (INTERNATIONAL CONFERENCE OF ANTIMICROBIAL AGENTS AND CHEMOTHERAPY), NEW ORLEANS, LOUISIANA, USA, SEPTEMBER 15-18, 1996. ABSTRACTS OF THE INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 36 (0). 1996. 158., XP002048789 * |
HELMINEN, MERJA E. ET AL: "Human immune response against outer membrane proteins of Moraxella (Branhamella) catarrhalis determined by immunoblotting and enzyme immunoassay", CLIN. DIAGN. LAB. IMMUNOL. (1995), 2(1), 35-9 CODEN: CDIMEN;ISSN: 1071-412X, 1995, XP002048788 * |
MERJA E. HELMINEN: "A major outer membrane protein of Moraxella catarrhalis is a target for antibodies that enhance pulmonary clearance of the pathogen in an animal model", INFECTION AND IMMUNITY, vol. 61, no. 5, May 1993 (1993-05-01), WASHINGTON US, pages 2003 - 2010, XP002048787 * |
Also Published As
Publication number | Publication date |
---|---|
WO1998006851A2 (en) | 1998-02-19 |
CA2262748A1 (en) | 1998-02-19 |
EP0920513A2 (en) | 1999-06-09 |
AU4150097A (en) | 1998-03-06 |
AU740481B2 (en) | 2001-11-08 |
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