WO1997045542A3 - Cell growth regulatory genes - Google Patents
Cell growth regulatory genes Download PDFInfo
- Publication number
- WO1997045542A3 WO1997045542A3 PCT/US1997/009584 US9709584W WO9745542A3 WO 1997045542 A3 WO1997045542 A3 WO 1997045542A3 US 9709584 W US9709584 W US 9709584W WO 9745542 A3 WO9745542 A3 WO 9745542A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- genes
- cgr11
- cgr19
- cell growth
- cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y303/00—Hydrolases acting on ether bonds (3.3)
- C12Y303/02—Ether hydrolases (3.3.2)
- C12Y303/02009—Microsomal epoxide hydrolase (3.3.2.9), i.e. styreneepoxide hydrolase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU32281/97A AU3228197A (en) | 1996-05-29 | 1997-05-29 | Cell growth regulatory genes |
CA002256498A CA2256498A1 (en) | 1996-05-29 | 1997-05-29 | Cell growth regulatory genes |
JP09543058A JP2000512494A (en) | 1996-05-29 | 1997-05-29 | Cell growth regulatory gene |
EP97927946A EP0914338A2 (en) | 1996-05-29 | 1997-05-29 | Cell growth regulatory genes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1855796P | 1996-05-29 | 1996-05-29 | |
US60/018,557 | 1996-05-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1997045542A2 WO1997045542A2 (en) | 1997-12-04 |
WO1997045542A3 true WO1997045542A3 (en) | 1998-05-07 |
Family
ID=21788559
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/009584 WO1997045542A2 (en) | 1996-05-29 | 1997-05-29 | Cell growth regulatory genes |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0914338A2 (en) |
JP (1) | JP2000512494A (en) |
AU (1) | AU3228197A (en) |
CA (1) | CA2256498A1 (en) |
WO (1) | WO1997045542A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8382998A (en) * | 1997-07-02 | 1999-01-25 | Genzyme Corporation | P53 influenced gene expression |
WO1999015661A1 (en) * | 1997-09-22 | 1999-04-01 | Incyte Pharmaceuticals, Inc. | Cell growth regulator |
IL126024A0 (en) * | 1998-03-19 | 1999-05-09 | Yeda Res & Dev | Modulators of the function of receptors of the tnf/ngf receptor family and other proteins |
US7745579B1 (en) | 1998-09-01 | 2010-06-29 | David Wallach | Inhibitor of NF-KB activation |
GB0109008D0 (en) * | 2001-04-10 | 2001-05-30 | Oxford Biomedica Ltd | Novel genes |
WO2006098304A1 (en) * | 2005-03-15 | 2006-09-21 | Saitama University | Novel secretory protein derived from pituitary cell and use of the same |
JP2008063244A (en) * | 2006-09-05 | 2008-03-21 | Saitama Univ | Treatment or prevention of saccharometabolism abnormality |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995013375A1 (en) * | 1993-11-10 | 1995-05-18 | The Johns Hopkins University | Tumor suppressor waf1 |
WO1996001907A1 (en) * | 1994-07-12 | 1996-01-25 | Bristol-Myers Squibb Company | NOVEL p53 RESPONSE GENES |
-
1997
- 1997-05-29 EP EP97927946A patent/EP0914338A2/en not_active Withdrawn
- 1997-05-29 CA CA002256498A patent/CA2256498A1/en not_active Abandoned
- 1997-05-29 AU AU32281/97A patent/AU3228197A/en not_active Abandoned
- 1997-05-29 WO PCT/US1997/009584 patent/WO1997045542A2/en not_active Application Discontinuation
- 1997-05-29 JP JP09543058A patent/JP2000512494A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995013375A1 (en) * | 1993-11-10 | 1995-05-18 | The Johns Hopkins University | Tumor suppressor waf1 |
WO1996001907A1 (en) * | 1994-07-12 | 1996-01-25 | Bristol-Myers Squibb Company | NOVEL p53 RESPONSE GENES |
Non-Patent Citations (7)
Title |
---|
BAUER D. ET AL.: "Identification of differentially expressed mRNA species by an improved display technique.", NUCLEIC ACIDS RESEARCH, vol. 21, no. 18, 1993, pages 4272 - 4280, XP000394394 * |
BUCKBINDER L. ET AL.: "Gene regulation by temperature-sensitive p53 mutants: Identification of p53 response genes.", PROC. NATL. ACAD. SCI. USA, vol. 91, 1994, pages 10640 - 10644, XP002046023 * |
EL-DEIRY W.S. ET AL.: "WAF1, a potential mediator of p53 tumor suppression.", CELL, vol. 75, 1993, pages 817 - 825, XP002046022 * |
EMBL database entry HS52516; accession number T33525; 9. September 1995; Adams M.D. et al.: 'Initial assessment of human gene diver- sity and expression patterns based upon 52million basepairs of cDNA sequence.' * |
MADDEN S.L. ET AL.: "Induction of cell growth regulatory genes by p53.", CANCER RESEARCH, vol. 56, 1 December 1996 (1996-12-01), pages 5384 - 5390, XP002046025 * |
MICHALOVITZ D. ET AL.: "Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.", CELL, vol. 62, 1990, pages 671 - 680, XP002046026 * |
OKAMOTO K. AND BEACH D.: "Cyclin G is a transcriptional target of the p53 tumor suppressor protein.", EMBO JOURNAL, vol. 13, no. 19, 1994, pages 4816 - 4822, XP002046024 * |
Also Published As
Publication number | Publication date |
---|---|
AU3228197A (en) | 1998-01-05 |
CA2256498A1 (en) | 1997-12-04 |
WO1997045542A2 (en) | 1997-12-04 |
JP2000512494A (en) | 2000-09-26 |
EP0914338A2 (en) | 1999-05-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Wright | The genetics of biogenic amine metabolism, sclerotization, and melanization in Drosophila melanogaster | |
Baumhueter et al. | HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF. | |
Fiol et al. | A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression. | |
Park et al. | The role of the CCAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP) | |
Bois-Joyeux et al. | Members of the CAAT/enhancer-binding protein, hepatocyte nuclear factor-1 and nuclear factor-1 families can differentially modulate the activities of the rat α-fetoprotein promoter and enhancer | |
Hirose et al. | In vitro transcription of eukaryotic genes is affected differently by the degree of DNA supercoiling. | |
Galéra et al. | c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin. | |
Zhang et al. | Localization of DNA protein-binding sites in the proximal and distal promoter regions of the mouse alpha-fetoprotein gene. | |
Li et al. | Cooperative effects of C/EBP-like and NF x B-like binding sites on rat serum amyloid A1 gene expression in liver cells | |
Shaskus et al. | A bifunctional genetic regulatory element of the rat dopamine beta-hydroxylase gene influences cell type specificity and second messenger-mediated transcription. | |
Kubo et al. | DNA topoisomerase IIα gene expression under transcriptional control in etoposide/teniposide-resistant human cancer cells | |
WO1997045542A3 (en) | Cell growth regulatory genes | |
Coker III et al. | Characterization of rat and human tyrosine hydroxylase genes: functional expression of both promoters in neuronal and non-neuronal cell types | |
Li et al. | Two adjacent C/EBP-binding sequences that participate in the cell-specific expression of the mouse serum amyloid A3 gene | |
Wight et al. | The first intron of the myelin proteolipid protein gene confers cell type-specific expression by a transcriptional repression mechanism in non-expressing cell types | |
Zhang | Characterization of the 5′ flanking region of the human MnSOD gene | |
Kazunori et al. | Epoc-1: a POU-domain gene expressed in murine epidermal basal cells and thymic stromal cells | |
Argenton et al. | The transcriptional regulation of the growth hormone gene is conserved in vertebrate evolution | |
St-Arnaud et al. | Wnt-1-inducing factor-1: a novel G/C box-binding transcription factor regulating the expression of Wnt-1 during neuroectodermal differentiation | |
Tashiro et al. | A calcium-dependent protease selectively degrading the 160 000 Mr component of neurofilaments is associated with the cytoskeletal preparation of the spinal cord and has an endogenous inhibitory factor | |
Cassuto et al. | Involvement of HNF-1 in the regulation of phosphoenolpyruvate carboxykinase gene expression in the kidney | |
Kim et al. | Unique sequence organization and erythroid cell-specific nuclear factor-binding of mammalian Θ I globin promoters | |
Liu et al. | Regulation of phosphoenolpyruvate carboxykinase (GTP) gene transcription | |
Borrello et al. | Manganese deficiency and transcriptional regulation of mitochondrial superoxide dismutase in hepatomas | |
WANG et al. | The p69/71 2-5A synthetase promoter contains multiple regulatory elements required for interferon-α-induced expression |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG UZ VN AM AZ BY KG KZ MD RU TJ TM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH KE LS MW SD SZ UG AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2256498 Country of ref document: CA Ref country code: CA Ref document number: 2256498 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1997927946 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWP | Wipo information: published in national office |
Ref document number: 1997927946 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1997927946 Country of ref document: EP |