WO1997038131A1 - Method for detecting a nucleic acid chain to be analysed - Google Patents

Method for detecting a nucleic acid chain to be analysed Download PDF

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Publication number
WO1997038131A1
WO1997038131A1 PCT/RU1996/000087 RU9600087W WO9738131A1 WO 1997038131 A1 WO1997038131 A1 WO 1997038131A1 RU 9600087 W RU9600087 W RU 9600087W WO 9738131 A1 WO9738131 A1 WO 9738131A1
Authority
WO
WIPO (PCT)
Prior art keywords
analysed
detecting
nucleic acid
acid chain
chain
Prior art date
Application number
PCT/RU1996/000087
Other languages
French (fr)
Russian (ru)
Inventor
Valentina Filippovna Kulikova
Evgenia Mikhailovna Ivanova
Dmitry Vladimirovich Pyshny
Sergei Georgievich Lokhov
Anzhelika Anatolievna Krivenko
Grigory Moiseevich Dymshits
Original Assignee
Valentina Filippovna Kulikova
Evgenia Mikhailovna Ivanova
Dmitry Vladimirovich Pyshny
Sergei Georgievich Lokhov
Anzhelika Anatolievna Krivenko
Grigory Moiseevich Dymshits
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valentina Filippovna Kulikova, Evgenia Mikhailovna Ivanova, Dmitry Vladimirovich Pyshny, Sergei Georgievich Lokhov, Anzhelika Anatolievna Krivenko, Grigory Moiseevich Dymshits filed Critical Valentina Filippovna Kulikova
Priority to PCT/RU1996/000087 priority Critical patent/WO1997038131A1/en
Priority to RU98100753A priority patent/RU2146707C1/en
Priority to FR9704290A priority patent/FR2747396B3/en
Publication of WO1997038131A1 publication Critical patent/WO1997038131A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method for detecting a nucleic acid chain which is to be analysed and contains point mutations. According to this method, an oligonucleotide probe, which is 4 to 6 elements in length, is bonded at both ends to the corresponding complementary oligonucleotides of the chain to be analysed, or to their derivatives bearing polycyclic aromatic groups.
PCT/RU1996/000087 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed WO1997038131A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/RU1996/000087 WO1997038131A1 (en) 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed
RU98100753A RU2146707C1 (en) 1996-04-11 1996-04-11 Method of detection of analyzed sequence of nucleic acid
FR9704290A FR2747396B3 (en) 1996-04-11 1997-04-08 METHOD FOR DETECTING A SEQUENCE OF NUCLEIC ACID TO BE ANALYZED

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU1996/000087 WO1997038131A1 (en) 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed

Publications (1)

Publication Number Publication Date
WO1997038131A1 true WO1997038131A1 (en) 1997-10-16

Family

ID=20129992

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU1996/000087 WO1997038131A1 (en) 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed

Country Status (3)

Country Link
FR (1) FR2747396B3 (en)
RU (1) RU2146707C1 (en)
WO (1) WO1997038131A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7108973B2 (en) * 2002-03-20 2006-09-19 Ken-Shwo Dai Human PEN11B-related gene variant associated with lung cancers

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012003330A2 (en) * 2010-06-30 2012-01-05 Stratos Genomics, Inc Multiplexed identification of nucleic acid sequences

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935341A (en) * 1986-06-04 1990-06-19 Whitehead Institute For Biomedical Research Detection of point mutations in neu genes
SU1678838A1 (en) * 1989-05-03 1991-09-23 Всесоюзный научно-исследовательский институт биологического приборостроения Method for detection of nucleotide sequence
WO1991019812A1 (en) * 1990-06-11 1991-12-26 Bio Merieux Method for detecting a nucleotide sequence by sandwich hybridization
WO1992006216A1 (en) * 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Nucleic acid sensitive detection process
WO1992008808A1 (en) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935341A (en) * 1986-06-04 1990-06-19 Whitehead Institute For Biomedical Research Detection of point mutations in neu genes
SU1678838A1 (en) * 1989-05-03 1991-09-23 Всесоюзный научно-исследовательский институт биологического приборостроения Method for detection of nucleotide sequence
WO1991019812A1 (en) * 1990-06-11 1991-12-26 Bio Merieux Method for detecting a nucleotide sequence by sandwich hybridization
WO1992006216A1 (en) * 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Nucleic acid sensitive detection process
WO1992008808A1 (en) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7108973B2 (en) * 2002-03-20 2006-09-19 Ken-Shwo Dai Human PEN11B-related gene variant associated with lung cancers

Also Published As

Publication number Publication date
FR2747396B3 (en) 1998-07-17
FR2747396A1 (en) 1997-10-17
RU2146707C1 (en) 2000-03-20

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