WO1997028752A1 - Dispositif et procede d'epilation au laser - Google Patents

Dispositif et procede d'epilation au laser Download PDF

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Publication number
WO1997028752A1
WO1997028752A1 PCT/GB1997/000354 GB9700354W WO9728752A1 WO 1997028752 A1 WO1997028752 A1 WO 1997028752A1 GB 9700354 W GB9700354 W GB 9700354W WO 9728752 A1 WO9728752 A1 WO 9728752A1
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WIPO (PCT)
Prior art keywords
laser radiation
target area
accordance
laser
source
Prior art date
Application number
PCT/GB1997/000354
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English (en)
Inventor
Gary Lewis Jones
Neville Richard Ledger
David Simon George
Robert Marc Clement
Original Assignee
Gary Lewis Jones
Neville Richard Ledger
David Simon George
Robert Marc Clement
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gary Lewis Jones, Neville Richard Ledger, David Simon George, Robert Marc Clement filed Critical Gary Lewis Jones
Priority to AU16134/97A priority Critical patent/AU1613497A/en
Publication of WO1997028752A1 publication Critical patent/WO1997028752A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A61B2018/00476—Hair follicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/2035—Beam shaping or redirecting; Optical components therefor
    • A61B2018/20351—Scanning mechanisms
    • A61B2018/20359—Scanning mechanisms by movable mirrors, e.g. galvanometric

Definitions

  • the present invention relates both to a depilation apparatus and to method of depilation.
  • Depilation the removal of body hair
  • the medical requirement may be due to the need for a skin graft from one area supporting hair growth to another where hair growth is not wanted.
  • Medical applications however create a very limited market and hence a small commercial opportunity.
  • 30% of the population of the developed world require cosmetic depilation at some time or other. If a technique could be developed to offer successful depilation for an extended period then a very major commercial opportunity would emerge.
  • the anagen phase is the first of these phases and occurs at a time when growth is initiated and lasts for a period of several weeks or even years depending on the location of the hair on the body. At the end of this period growth is suspended and the hair root becomes detached from the papilla.
  • This phase is known as the catagen phase. From now on no more length is added to the hair but nevertheless it can remain held in the follicle for a period of several weeks if not months.
  • This final phase of the cycle is known as the telogen phase.
  • the dermal papilla is dormant, but can be stimulated back into action prematurely by the mechanical removal of the hair from the follicle by, for example, brushing. Failing this the old hair would be naturally pushed out of the follicle at the beginning of the next growth cycle as a new hair is initiated in the anagen phase.
  • the outer root sheath is contiguous with the epidermis, and encloses a region of cells known as the bulge.
  • the reason for this is thought to be that the bulge contains stem cells for the growth of the dermal papilla so that, even if the papilla is completely removed or destroyed, a full recovery can be made by the recolonisation of the dermal papilla by these stem cells.
  • the technique essentially consists of the application of a 5mm spot of laser light with an energy density of 5-20 J/cm 2 , applied spot by spot over the whole area to be depilated. Consequently, the depilation process is comparatively slow.
  • the attenuation of laser radiation as it passes through tissue is dependent not only on absorption but also on scattering. Nevertheless it is the absorption of the radiation by melanin and haemoglobin that is of particular importance as it is the selective photothermolysis by melanin that is the basis of laser depilation.
  • the attenuation of radiation due to the absorption by these two chromophores can be represented at one level by the equation:
  • d is the tissue depth
  • a m (X)l is the absorption coefficient of melanin at wavelength 1
  • o is the absorption coefficient of haemoglobin at wavelength 2
  • K is a constant
  • the depth at which light is attenuated to 1/e of its original value is called the penetration depth, and it can easily be shown from the above equation that this is equal to 1/ ⁇ .
  • the absorption coefficient is highly dependent on the absorption coefficients of melanin and haemoglobin. Outside this range other chromophores begin to contribute significantly to the absorption process. For example, water at longer wavelengths and proteins at shorter ones. Nevertheless it can be deduced from this that for radiation wavelengths between these limits the penetration depth is determined predominantly by the absorption coefficients of melanin and haemoglobin.
  • An important result of the variation in penetration depth with wavelength is that the amount of energy that can be deposited in the required region will have a reciprocal dependence. Therefore if it is desired that the greatest deposition of energy is at the surface then a shorter wavelength should it be used.
  • a further complication in determing the exposure levels required for treatment is produced by the need to include relaxation times. Relaxation times play an important role because of the need to get enough heat into a particular area to induce sufficient damage to cause cell death without at the same time causing unnecessary damage to the surrounding areas which could lead to scarring. Energy must be deposited into the area fast enough to compensate for any losses by conduction but also at a rate slow enough so that excessively rapid rises in temperature, and therefore explosive tissue heating, is avoided. Generally speaking there are three modes of laser - tissue interactions; photochemical, photothermal and photoionisation. The duration of the pulse, wavelength and output power of a laser will determine which of these interactions is dominant in any particular situation.
  • photothermal interactions are those in which the pulse length is around the same time or longer than the thermal relaxation time of the tissue, whereas photoionisation dominates when the pulse length is relatively short.
  • the photothermal reactions can therefore be subdivided into two terms of interest, the radiant heat effect, which is the initial heating of the target tissue by the incident radiation, and the conductive heat effect which is the transfer of the radiant heat to the surrounding tissue.
  • Optimum laser pulse lengths are determined partly by the relaxation times and partly by treatment time considerations.
  • an apparatus for the depilation of mammalian tissue comprising a continuous wave laser diode.
  • the laser diode is capable of applying 5 to 20 J/cm 2 of laser energy to each region of the tissue to be depilated for a period of 500 to lOOO ⁇ s.
  • an apparatus for the depilation of mammalian tissue comprising a source of laser radiation adapted to irradiate a target area with continuous wave or quasi continuous wave laser radiation having a wavelength in the range from 600nm to llOOnm and an energy density in the target area of between 2 J/cm 2 and 25 J/cm 2 for a duration of between 200 ⁇ s and 5000 ⁇ s so as to thereby selectively fatally damage the sub-dermal biological material associated with hair growth.
  • the source of laser radiation may be a laser diode.
  • the laser radiation may have a wavelength in the range from 630nm to llOOnm.
  • the laser radiation may have a wavelength in the range from 780nm to 860nm.
  • Advantageously means may be provided for adapting the spatial characteristics of the laser radiation so as to form a line of light with which to illuminate the target area.
  • the source of laser radiation may emit quasi continuous wave laser radiation at a sufficiently high frequency to simulate continuous wave absorption in the target area.
  • the source of laser radiation may be operated at a frequency such that the thermal relaxation time of the tissue in the target area is longer than an individual pulse cycle duration such that the resulting thermal experience is the same as that of a continuous illumination of equivalent energy.
  • the source of laser radiation may be operated at a frequency falling within the range from lOHz to 10kHz and most preferably at a frequency of approximately 1kHz .
  • Advantageously means may be provided for directing a beam of the laser radiation at a portion of the target so as to form an illuminated area and means for scanning the beam of laser radiation so that the illuminated area moves across the target area until all of the target area has been illuminated.
  • the scanning means may be adapted to scan the beam of laser radiation at a constant speed.
  • the scanning means may be adapted to scan the beam of laser radiation across the target area with an increasing speed between successive portions of the target area.
  • the scanning means may be adapted to scan the beam of laser radiation across the target area at varying speeds so as to maximise the ratio of the exposure time of individual portions of the target area to the time taken to scan the beam between successive portions of the target area.
  • the scanning means may be adapted to scan the beam of laser radiation across the target area to selectively illuminate individual portions of the target in a predetermined sequence so as to minimise unwanted thermal damage.
  • the scanning means may comprise one or more galvanometric scanners and/or deflecting media.
  • the deflecting media may include one or more mirrors or one or more acousto-optical scanners.
  • Advantageously means may be provided for varying the energy delivery of the laser radiation by modulating the output of the source of laser radiation external to the laser cavity thereby regulating the time of illumination of each individual portion of the target area.
  • means may be provided for varying the energy delivery of the laser radiation by modulating the output of the source of laser radiation by varying input power to the laser cavity without the loss of continuous stimulated emission.
  • a method for the depilation of mammalian tissue comprising the steps of providing a source of laser radiation, directing the laser radiation at a target area, and illuminating the target area with continuous wave or quasi continuous wave laser radiation having a wavelength in the range from 600nm to llOOnm and an energy density in the target area of between 2 J/cm 2 and 25 J/cm 2 for a duration of between 200 ⁇ s and 5000 ⁇ s so as to thereby selectively fatally damage the sub-dermal biological material associated with hair growth.
  • the source of laser radiation may comprise a laser diode.
  • the laser radiation may have a wavelength in the range from 630nm to llOOnm.
  • the laser radiation may have a wavelength in the range from 780nm to 860nm.
  • the step of illuminating the target area may include adapting the spatial characteristics of the laser radiation so as to form a line of light on the target area.
  • the source of laser radiation may emit quasi continuous wave laser radiation at a sufficiently high frequency to simulate continuous wave absorption in the target area.
  • the source of laser radiation is operated at a frequency such that the thermal relaxation time of the tissue in the target area is longer than an individual pulse cycle duration such that the resulting thermal experience is the same as that of a continuous illumination of equivalent energy.
  • the source of laser radiation is operated at a frequency falling within the range from 10Hz to 10kHz and most preferably at a frequency of approximately 1kHz .
  • the target area may be illuminated by directing a beam of the laser radiation at a portion of the target so as to form an illuminated area and scanning the beam of laser radiation so that the illuminated area moves across the target area until all of the target area has been illuminated.
  • the beam of laser radiation may be scanned at a constant speed.
  • the beam of laser radiation may be scanned across the target area with an increasing speed between successive portions of the target area.
  • the beam of laser radiation may be scanned across the target area at varying speeds so as to maximise the ratio of the exposure time of individual portions of the target area to the time taken to scan the beam between successive portions of the target area.
  • the beam of laser radiation may be scanned across the target area to selectively illuminate individual portions of the target in a predetermined sequence so as to minimise unwanted thermal damage.
  • the beam of laser radiation may be scanned using one or more galvanometric scanners and/or deflecting media.
  • the deflecting media may comprise one or more mirrors or one or more acousto- optical scanners.
  • the energy delivery may be varied by modulating the output of the source of laser radiation external to the laser cavity thereby regulating the time of illumination of each individual portion of the target area.
  • the energy delivered may be varied by modulating the output of the source of laser radiation by varying the input power to the laser cavity without the loss of continuous stimulated emission.
  • depilation is best achieved by illumination of the skin with light of an appropriate wavelength at a pulse duration of 400 to lOOO ⁇ s and an energy density of 10 to 20 J/cm 2 .
  • the laser technology currently available will produce such output parameters at a rate of 1Hz ie at one pulse per second. This means that the laser will produce of the order of 4 Joules per second.
  • the pulse will only cover a circular area of, say, 5mm in diameter.
  • the diode laser used is 60 CW, then by definition it produces 60 Joules of energy every second. This is far greater than the energy produced by established technology. However, the diode laser will not produce the peak powers that the ruby technology generates. This limitation poses a dilemma which can be overcome by applying the following theory.
  • one currently preferred embodiment of the present invention involves controlling a continuous wave or quasi CW laser source to provide sufficient energy to mammalian tissue to selectively and fatally damage the sub-dermal biological material associated with hair growth.
  • the laser output is directed by a scanning system capable of covering an area of approximately 300mm 2 .
  • the beam itself having an area of approximately 4 x I0 "3 cm 2 .
  • the scanning system directs the beam from point to point illuminating an area equal to that of the cross- sectional area of the beam at the target for a given time so as to deliver sufficient energy to permanently suppress hair growth.
  • the embodiment is shown schematically in Figure 3 to comprise a CW or quasi CW laser source 1 powered by a laser power supply 4.
  • the laser source 1 emits a laser beam 3 to a scanning system 2 which then redirects the laser beam 7 so as to illuminate a portion of a target area 6 of mammalian tissue 5.
  • the energy delivered to each portion of the target having an area equal to the size of the beam, is controlled by the power of the laser and the time of exposure for that individual portion. Typically an energy density of 15 J/cm 2 is required to create the depilation effect.
  • a spot size of 4 x IO "3 cm 2 and an exposure time of lOOO ⁇ s (ie approximately equal to the thermal relaxation time for tissue) 60 mJ of energy will be delivered to that portion of the target.
  • adjacent portions of the target may be illuminated successively as shown in Figure 4 by scanning the beam 7 in the direction of arrow 8 until the entire target area has been illuminated.
  • One advantage of this method is that a larger area of tissue can be treated in a given time period when compared to pulsed laser depilation systems. Even though the spot size of a pulsed laser is generally larger than that of the embodiment described, the pulsed laser systems suffer from the disadvantage that they are only capable of delivering a single pulse of energy at a low duty cycle, for example, 1Hz. Overall, this results in a slower treatment time. By using a continuous wave output and combining that with a means of accurately directing the laser beam, a simulated higher frequency of operation results and the desired reduction of treatment time is achieved.

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Electromagnetism (AREA)
  • Radiology & Medical Imaging (AREA)
  • Otolaryngology (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

L'invention concerne un dispositif servant à effectuer l'épilation de tissu mammifère (5) et comprenant une source de rayonnement laser (1) conçue pour irradier une zone cible (6) par un rayonnement laser (7) à onde continue ou quasi continue possédant une longueur d'onde située dans une plage de 600 nm à 1100 nm et une densité d'énergie dans la zone cible située entre 2 J/cm2 et 25 J/cm2 pendant une durée comprise entre 200 νs et 5000 νs, de manière à détruire sélectivement le matériau biologique sous-dermique associé à la croissance de la pilosité. Elle concerne également un procédé servant à effectuer l'épilation de tissu mammifère (5) et consistant, à partir d'une source (1) de rayonnement laser, à diriger le rayonnement laser (7) sur une zone cible (6) et à exposer la zone cible (6) à un rayonnement laser à onde continue ou quasi continue possédant une longueur d'ondes située dans une plage de 600 nm à 1100 nm et une densité d'énergie dans la zone cible située entre 2 J/cm2 et 25 J/cm2 pendant une durée comprise entre 200 νs et 5000 νs, de manière à détruire sélectivement le matériau biologique sous-dermique associé à la croissance de la pilosité.
PCT/GB1997/000354 1996-02-06 1997-02-06 Dispositif et procede d'epilation au laser WO1997028752A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU16134/97A AU1613497A (en) 1996-02-06 1997-02-06 Laser depilation apparatus and method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9602375.9 1996-02-06
GBGB9602375.9A GB9602375D0 (en) 1996-02-06 1996-02-06 Laser depilation apparatus and method

Publications (1)

Publication Number Publication Date
WO1997028752A1 true WO1997028752A1 (fr) 1997-08-14

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AU (1) AU1613497A (fr)
GB (1) GB9602375D0 (fr)
ID (1) ID20579A (fr)
WO (1) WO1997028752A1 (fr)
ZA (1) ZA97968B (fr)

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029245A1 (fr) * 1997-12-10 1999-06-17 Quon David W Procede et appareil d'epilation permanente
DE19804385A1 (de) * 1998-02-04 1999-08-12 Nwl Laser Tech Gmbh Vorrichtung und Verfahren zur Haarentfernung von behaarten menschlichen oder tierischen Hautoberflächen mit einem Laser
WO1999043264A1 (fr) * 1998-02-24 1999-09-02 Palomar Medical Technologies, Inc. Procede et appareil d'epilation
WO1999060937A1 (fr) * 1998-05-26 1999-12-02 Keralase Ltd. Procede d'epilation par lumiere laser transcutanee
WO2000024464A1 (fr) * 1998-10-28 2000-05-04 Keralase Ltd. Procede d'epilation par application transcutanee de lumiere laser
WO2000040162A1 (fr) * 1999-01-06 2000-07-13 Keralase Ltd. Procede d'epilation par rayonnement laser transcutane
WO2000053114A1 (fr) * 1999-03-05 2000-09-14 Icn Photonics Limited Reduction de rides de la peau a l'aide d'une lumiere pulsee
WO2000056240A1 (fr) * 1999-03-19 2000-09-28 Asah Medico A/S Appareil de traitement de tissus
US6443946B2 (en) 1996-08-29 2002-09-03 Icn Photonics Limited Apparatus for wrinkle removal
EP1482848A1 (fr) * 2002-03-12 2004-12-08 Palomar Medical Technologies, Inc. Procede et appareil pour activer la croissance capillaire
WO2005016453A1 (fr) 2003-08-18 2005-02-24 Koninklijke Philips Electronics N.V. Methode et dispositif de regulation optique de faible intensite de la croissance des poils
US7488317B2 (en) 2004-10-12 2009-02-10 Dectronique (1984) Inc. Electro-epilation method
US8328796B2 (en) 1997-05-15 2012-12-11 Palomar Medical Technologies, Inc. Light energy delivery head
US8346347B2 (en) 2005-09-15 2013-01-01 Palomar Medical Technologies, Inc. Skin optical characterization device
US8915948B2 (en) 2002-06-19 2014-12-23 Palomar Medical Technologies, Llc Method and apparatus for photothermal treatment of tissue at depth
US9028536B2 (en) 2006-08-02 2015-05-12 Cynosure, Inc. Picosecond laser apparatus and methods for its operation and use
US9780518B2 (en) 2012-04-18 2017-10-03 Cynosure, Inc. Picosecond laser apparatus and methods for treating target tissues with same
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
US10245107B2 (en) 2013-03-15 2019-04-02 Cynosure, Inc. Picosecond optical radiation systems and methods of use
US10434324B2 (en) 2005-04-22 2019-10-08 Cynosure, Llc Methods and systems for laser treatment using non-uniform output beam
US10518106B2 (en) 2005-06-24 2019-12-31 Koninklijke Philips N.V. Device and method for low intensity optical hair growth control
US11418000B2 (en) 2018-02-26 2022-08-16 Cynosure, Llc Q-switched cavity dumped sub-nanosecond laser

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916143A (en) * 1971-04-22 1975-10-28 Research Corp Branding living animals
WO1984002644A1 (fr) * 1981-05-21 1984-07-19 Howard R Weissman Procede et dispositif d'epilation au laser
FR2571264A1 (fr) * 1984-10-04 1986-04-11 Navarro Christian Dispositif emetteur de rayons laser pour utilisation medicale
DE3837248A1 (de) * 1988-10-28 1990-05-03 Teichmann Heinrich Otto Dr Phy Einrichtung zur behandlung von hautveraenderungen
US4973848A (en) * 1989-07-28 1990-11-27 J. Mccaughan Laser apparatus for concurrent analysis and treatment
US5059192A (en) * 1990-04-24 1991-10-22 Nardo Zaias Method of hair depilation
WO1993021993A1 (fr) * 1992-04-24 1993-11-11 Kim Robin Segal Laser a bas niveau pour le traitement de tissus mous
WO1995015725A1 (fr) * 1993-12-08 1995-06-15 Sls (Wales) Limited Epilation

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916143A (en) * 1971-04-22 1975-10-28 Research Corp Branding living animals
WO1984002644A1 (fr) * 1981-05-21 1984-07-19 Howard R Weissman Procede et dispositif d'epilation au laser
FR2571264A1 (fr) * 1984-10-04 1986-04-11 Navarro Christian Dispositif emetteur de rayons laser pour utilisation medicale
DE3837248A1 (de) * 1988-10-28 1990-05-03 Teichmann Heinrich Otto Dr Phy Einrichtung zur behandlung von hautveraenderungen
US4973848A (en) * 1989-07-28 1990-11-27 J. Mccaughan Laser apparatus for concurrent analysis and treatment
US5059192A (en) * 1990-04-24 1991-10-22 Nardo Zaias Method of hair depilation
WO1993021993A1 (fr) * 1992-04-24 1993-11-11 Kim Robin Segal Laser a bas niveau pour le traitement de tissus mous
WO1995015725A1 (fr) * 1993-12-08 1995-06-15 Sls (Wales) Limited Epilation

Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6443946B2 (en) 1996-08-29 2002-09-03 Icn Photonics Limited Apparatus for wrinkle removal
US6544255B2 (en) 1997-04-04 2003-04-08 Keralase Ltd. Method of hair removal by transcutaneous application of laser light
US8328796B2 (en) 1997-05-15 2012-12-11 Palomar Medical Technologies, Inc. Light energy delivery head
WO1999029245A1 (fr) * 1997-12-10 1999-06-17 Quon David W Procede et appareil d'epilation permanente
DE19804385B4 (de) * 1998-02-04 2004-10-28 Nwl Laser-Technologie Gmbh Vorrichtung und Verfahren zur Haarentfernung von behaarten menschlichen oder tierischen Hautoberflächen mit einem Laser
DE19804385A1 (de) * 1998-02-04 1999-08-12 Nwl Laser Tech Gmbh Vorrichtung und Verfahren zur Haarentfernung von behaarten menschlichen oder tierischen Hautoberflächen mit einem Laser
WO1999043264A1 (fr) * 1998-02-24 1999-09-02 Palomar Medical Technologies, Inc. Procede et appareil d'epilation
US6080146A (en) * 1998-02-24 2000-06-27 Altshuler; Gregory Method and apparatus for hair removal
WO1999060937A1 (fr) * 1998-05-26 1999-12-02 Keralase Ltd. Procede d'epilation par lumiere laser transcutanee
WO2000024464A1 (fr) * 1998-10-28 2000-05-04 Keralase Ltd. Procede d'epilation par application transcutanee de lumiere laser
WO2000040162A1 (fr) * 1999-01-06 2000-07-13 Keralase Ltd. Procede d'epilation par rayonnement laser transcutane
AU771801B2 (en) * 1999-03-05 2004-04-01 Euphotonics Limited Skin wrinkle reduction using pulsed light
US6881212B1 (en) 1999-03-05 2005-04-19 Icn Photonics Limited Skin wrinkle reduction using pulsed light
WO2000053114A1 (fr) * 1999-03-05 2000-09-14 Icn Photonics Limited Reduction de rides de la peau a l'aide d'une lumiere pulsee
US6607523B1 (en) 1999-03-19 2003-08-19 Asah Medico A/S Apparatus for tissue treatment
WO2000056240A1 (fr) * 1999-03-19 2000-09-28 Asah Medico A/S Appareil de traitement de tissus
EP1482848A4 (fr) * 2002-03-12 2007-08-15 Palomar Medical Tech Inc Procede et appareil pour activer la croissance capillaire
EP1482848A1 (fr) * 2002-03-12 2004-12-08 Palomar Medical Technologies, Inc. Procede et appareil pour activer la croissance capillaire
US10556123B2 (en) 2002-06-19 2020-02-11 Palomar Medical Technologies, Llc Method and apparatus for treatment of cutaneous and subcutaneous conditions
US8915948B2 (en) 2002-06-19 2014-12-23 Palomar Medical Technologies, Llc Method and apparatus for photothermal treatment of tissue at depth
US10500413B2 (en) 2002-06-19 2019-12-10 Palomar Medical Technologies, Llc Method and apparatus for treatment of cutaneous and subcutaneous conditions
JP2007502642A (ja) * 2003-08-18 2007-02-15 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ 低強度光学発毛制御装置及び方法
JP2011125739A (ja) * 2003-08-18 2011-06-30 Koninkl Philips Electronics Nv ヒトの皮膚における毛髪の成長を低減するためのデバイス
WO2005016453A1 (fr) 2003-08-18 2005-02-24 Koninklijke Philips Electronics N.V. Methode et dispositif de regulation optique de faible intensite de la croissance des poils
US9132279B2 (en) 2003-08-18 2015-09-15 Koninklijke Philips N.V. Device and method for low intensity optical hair growth control
US7488317B2 (en) 2004-10-12 2009-02-10 Dectronique (1984) Inc. Electro-epilation method
US10434324B2 (en) 2005-04-22 2019-10-08 Cynosure, Llc Methods and systems for laser treatment using non-uniform output beam
US10518106B2 (en) 2005-06-24 2019-12-31 Koninklijke Philips N.V. Device and method for low intensity optical hair growth control
US8346347B2 (en) 2005-09-15 2013-01-01 Palomar Medical Technologies, Inc. Skin optical characterization device
US11712299B2 (en) 2006-08-02 2023-08-01 Cynosure, LLC. Picosecond laser apparatus and methods for its operation and use
US9028536B2 (en) 2006-08-02 2015-05-12 Cynosure, Inc. Picosecond laser apparatus and methods for its operation and use
US10849687B2 (en) 2006-08-02 2020-12-01 Cynosure, Llc Picosecond laser apparatus and methods for its operation and use
US10966785B2 (en) 2006-08-02 2021-04-06 Cynosure, Llc Picosecond laser apparatus and methods for its operation and use
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
US11095087B2 (en) 2012-04-18 2021-08-17 Cynosure, Llc Picosecond laser apparatus and methods for treating target tissues with same
US10305244B2 (en) 2012-04-18 2019-05-28 Cynosure, Llc Picosecond laser apparatus and methods for treating target tissues with same
US9780518B2 (en) 2012-04-18 2017-10-03 Cynosure, Inc. Picosecond laser apparatus and methods for treating target tissues with same
US10581217B2 (en) 2012-04-18 2020-03-03 Cynosure, Llc Picosecond laser apparatus and methods for treating target tissues with same
US11664637B2 (en) 2012-04-18 2023-05-30 Cynosure, Llc Picosecond laser apparatus and methods for treating target tissues with same
US10765478B2 (en) 2013-03-15 2020-09-08 Cynosurce, Llc Picosecond optical radiation systems and methods of use
US11446086B2 (en) 2013-03-15 2022-09-20 Cynosure, Llc Picosecond optical radiation systems and methods of use
US10245107B2 (en) 2013-03-15 2019-04-02 Cynosure, Inc. Picosecond optical radiation systems and methods of use
US10285757B2 (en) 2013-03-15 2019-05-14 Cynosure, Llc Picosecond optical radiation systems and methods of use
US11418000B2 (en) 2018-02-26 2022-08-16 Cynosure, Llc Q-switched cavity dumped sub-nanosecond laser
US11791603B2 (en) 2018-02-26 2023-10-17 Cynosure, LLC. Q-switched cavity dumped sub-nanosecond laser

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AU1613497A (en) 1997-08-28

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