WO1997018238A3 - Crf analogs - Google Patents
Crf analogs Download PDFInfo
- Publication number
- WO1997018238A3 WO1997018238A3 PCT/EP1996/005010 EP9605010W WO9718238A3 WO 1997018238 A3 WO1997018238 A3 WO 1997018238A3 EP 9605010 W EP9605010 W EP 9605010W WO 9718238 A3 WO9718238 A3 WO 9718238A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- crf analogs
- crf
- analogs
- lipophilic
- pharmaceutical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
The present invention relates to lipophilic CRF analogs which are useful as active ingredients in pharmaceutical or diagnostic compositions.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95117940.7 | 1995-11-14 | ||
EP95117940 | 1995-11-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1997018238A2 WO1997018238A2 (en) | 1997-05-22 |
WO1997018238A3 true WO1997018238A3 (en) | 1997-07-03 |
Family
ID=8219816
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1996/005010 WO1997018238A2 (en) | 1995-11-14 | 1996-11-14 | Crf analogs |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO1997018238A2 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0516450A2 (en) * | 1991-05-31 | 1992-12-02 | The Salk Institute For Biological Studies | CRF analogs |
WO1996019499A2 (en) * | 1994-12-12 | 1996-06-27 | The Salk Institute For Biological Studies | Improved cyclic crf antagonists |
-
1996
- 1996-11-14 WO PCT/EP1996/005010 patent/WO1997018238A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0516450A2 (en) * | 1991-05-31 | 1992-12-02 | The Salk Institute For Biological Studies | CRF analogs |
WO1996019499A2 (en) * | 1994-12-12 | 1996-06-27 | The Salk Institute For Biological Studies | Improved cyclic crf antagonists |
Non-Patent Citations (6)
Title |
---|
CHROUSOS E.A.: "CRF: basic studies and clinical applications", PROG.NEURO-PSYCHOPHARMACOL.&BIOL.PSYCHIATRY, vol. 9, no. 4, 1985, pages 349 - 359, XP000673256 * |
GULYAS E.A.: "Potent, structurally constrained agonists and competitive antagonists of CRF", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 92, no. 23, 7 November 1995 (1995-11-07), WASHINGTON US, pages 10575 - 10579, XP000566934 * |
KORNREICH E.A: "Alanine series of oCRF; a structure-activity relationship study", JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, no. 10, 1992, WASHINGTON US, pages 1870 - 1876, XP002030859 * |
MARTINS E.A.: "Unidirectional specific and modulated brain to blood transport of CRF", NEUROENDOCRINOLOGY, vol. 63, no. 4, April 1996 (1996-04-01), pages 338 - 348, XP000673299 * |
RUEHMANN E.A.: "Design of new CRF analogues and molecular characterization of functional CRF receptors", SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 21, no. 1-3, 1995, pages 1845, XP000671597 * |
W.A.BANKS E.A: "peptides and the blood-brain barrier: lipophilicity as a predictor of permeability", BRAIN RESEARCH BULLETIN, vol. 15, no. 3, September 1985 (1985-09-01), pages 287 - 292, XP000673506 * |
Also Published As
Publication number | Publication date |
---|---|
WO1997018238A2 (en) | 1997-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2150251A1 (en) | Lyospheres comprising gonadotropin | |
AU7547196A (en) | 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | |
AU5945396A (en) | 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients | |
HUP9802822A3 (en) | Halobenzimidazol derivatives, intermediates, preparation thereof and microbocide compositions containing these compounds as active ingredients | |
WO1995017165A3 (en) | Tissue moisturizing and antimicrobial compositions | |
CA2177682A1 (en) | Antimicrobial Wipe Compositions | |
ZA967034B (en) | Pharmaceutical compositions. | |
AU2001289438A1 (en) | Pharmaceutical semi-solid composition of isotretinoin | |
AU6818196A (en) | Substituted 2,4-imidazolidinedione compounds as pharmaceutical active ingredients | |
ZA965294B (en) | Substituted 4-phenylaminothiazoles, their process of preparation and the pharmaceutical compositions containing them. | |
CA2361402A1 (en) | Bis-sulfonamides | |
ZA972147B (en) | Dimethyl-(3-aryl-but-3-enyl)-amine compounds as pharmaceutical active ingredients. | |
WO1996021468A3 (en) | Chemically modified interferon | |
WO1992014696A3 (en) | SUBSTITUTED α-AMINOALDEHYDES AND DERIVATIVES | |
CA2335551A1 (en) | Thyroid hormone analogues and methods for their preparation | |
WO1998019697A3 (en) | Novel pharmaceutical compositions | |
CA2340224A1 (en) | Nimesulide containing topical pharmaceutical compositions | |
HUP9801251A3 (en) | Aza bisphosphonic acid derivatives, herbicide compositions containing these compounds as active ingredients and use thereof | |
AU3025795A (en) | Compositions which are suitable for employment as antidotes to blood anticoagulants, and their use | |
HU9800120D0 (en) | Pharmaceutical compositions of neutral taste containing quinolon derivatives as active components | |
HUP9900365A3 (en) | N-aryl-1,2,4-triazolin-5-on derivatives, preparation and use thereof, insecticide, arachnicide and nematocide compositions containing these compounds as active ingredients | |
WO1999006388A8 (en) | Pharmaceutical compounds isolated from aristolochia taliscana | |
MY120683A (en) | New phenylamidine derivatives, processes for their preparation and their use as pharmaceuticals. | |
HUP9802430A3 (en) | 2-benzoyl-1,3-dioxo-cyclohexane derivatives, preparation, use and intermediates thereof, herbicide compositions containing these compounds as active ingredients | |
CA2337667A1 (en) | Dextran-leptin conjugates, pharmaceutical compositions and related methods |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): CA JP US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
NENP | Non-entry into the national phase |
Ref country code: JP Ref document number: 97518588 Format of ref document f/p: F |
|
NENP | Non-entry into the national phase |
Ref country code: CA |
|
122 | Ep: pct application non-entry in european phase |