WO1997017444A3 - Novel sperm receptors - Google Patents

Novel sperm receptors Download PDF

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Publication number
WO1997017444A3
WO1997017444A3 PCT/US1996/018002 US9618002W WO9717444A3 WO 1997017444 A3 WO1997017444 A3 WO 1997017444A3 US 9618002 W US9618002 W US 9618002W WO 9717444 A3 WO9717444 A3 WO 9717444A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptor
encodes
novel sperm
sequence
nucleic acid
Prior art date
Application number
PCT/US1996/018002
Other languages
French (fr)
Other versions
WO1997017444A2 (en
Inventor
Gabriele V Ronnett
Loren Walensky
Martial Ruat
Solomon H Snyder
Original Assignee
Univ Johns Hopkins Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins Med filed Critical Univ Johns Hopkins Med
Priority to AU11181/97A priority Critical patent/AU1118197A/en
Publication of WO1997017444A2 publication Critical patent/WO1997017444A2/en
Publication of WO1997017444A3 publication Critical patent/WO1997017444A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention provides a nucleic acid comprising a sequence that encodes a sperm receptor that is related to, but is different from, a receptor of the odorant receptor family. The present invention also provides a method of obtaining a nucleic acid that comprises a sequence that encodes a sperm receptor, as well as a means of using the elements of the invention in a method of contraception, a method of detecting autoimmune infertility, and a method of affecting fertility.
PCT/US1996/018002 1995-11-09 1996-11-08 Novel sperm receptors WO1997017444A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU11181/97A AU1118197A (en) 1995-11-09 1996-11-08 Novel sperm receptors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55618695A 1995-11-09 1995-11-09
US08/556,186 1995-11-09

Publications (2)

Publication Number Publication Date
WO1997017444A2 WO1997017444A2 (en) 1997-05-15
WO1997017444A3 true WO1997017444A3 (en) 1997-06-05

Family

ID=24220257

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/018002 WO1997017444A2 (en) 1995-11-09 1996-11-08 Novel sperm receptors

Country Status (2)

Country Link
AU (1) AU1118197A (en)
WO (1) WO1997017444A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780405B1 (en) * 1998-06-25 2001-12-28 Centre Nat Rech Scient NOVEL OLFACTORY RECEPTORS AND USES THEREOF
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7674891B2 (en) 2008-08-01 2010-03-09 International Flavors & Fragrances Inc. Nucleic acid molecules encoding GPR84
EP2421524B1 (en) 2009-04-20 2018-08-08 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
US8828953B2 (en) 2009-04-20 2014-09-09 NaZura BioHealth, Inc. Chemosensory receptor ligand-based therapies
US9901551B2 (en) 2009-04-20 2018-02-27 Ambra Bioscience Llc Chemosensory receptor ligand-based therapies
AU2011317140A1 (en) 2010-10-19 2013-05-30 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
HUE051738T2 (en) 2011-01-07 2021-03-29 Anji Pharma Us Llc Chemosensory receptor ligand-based therapies
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017585A1 (en) * 1991-04-05 1992-10-15 The Trustees Of Columbia University In The City Of New York Odorant receptors ans uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017585A1 (en) * 1991-04-05 1992-10-15 The Trustees Of Columbia University In The City Of New York Odorant receptors ans uses thereof

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
K. RAMING ET AL.: "Cloning and expression of odorant receptors", NATURE, vol. 361, 28 January 1993 (1993-01-28), MACMILLAN JOURNALS LTD., LONDON,UK, pages 353 - 356, XP002029937 *
L. BUCK AND R. AXEL: "A novel multigene family encode odorant receptors: A molecular basis for odor recognition", CELL, vol. 65, 5 April 1991 (1991-04-05), CELL PRESS,CAMBRIDGE,MA,US;, pages 175 - 187, XP002029935 *
M. PARMENTIER ET AL.: "Expression of members of the putative olfactory receptor gene family in mammalian germ cells", NATURE, vol. 355, 30 January 1992 (1992-01-30), MACMILLAN JOURNALS LTD., LONDON,UK, pages 453 - 455, XP002029936 *
P. NEF ET AL.: "Spatial pattern of receptor expression in the olfactory epithelium", PROC. NATL.ACAD SCI., vol. 89, October 1992 (1992-10-01), NATL. ACAD SCI.,WASHINGTON,DC,US;, pages 8948 - 8952, XP002029938 *
T.M. DAWSON ET AL.: "Beta-adrenergic receptor kinase-2 and beta-arrestin-2 as mediators of odorant-induced desensitization", SCIENCE, vol. 259, 5 February 1993 (1993-02-05), AAAS,WASHINGTON,DC,US, pages 825 - 829, XP002029939 *
WALENSKY L D ET AL: "Identification of novel members of the odorant receptor family in rat spermatids.", 25TH ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE, SAN DIEGO, CALIFORNIA, USA, NOVEMBER 11-16, 1995. SOCIETY FOR NEUROSCIENCE ABSTRACTS 21 (1-3). 1995. 131. ISSN: 0190-5295, XP000671308 *
WALENSKY L D ET AL: "Odorant receptors and desensitization proteins colocalize in mammalian sperm.", MOLECULAR MEDICINE (CAMBRIDGE) 1 (2). 1995. 130-141. ISSN: 1076-1551, January 1995 (1995-01-01), XP000671419 *
WALENSKY L D ET AL: "Roles for novel members of the odorant receptor family and sperm inositol 1,4,5-trisphosphate receptors in mammalian fertilization.", THIRTY-FIFTH ANNUAL MEETING OF THE AMERICAN SOCIETY FOR CELL BIOLOGY, WASHINGTON, D.C., USA, DECEMBER 9-13, 1995. MOLECULAR BIOLOGY OF THE CELL 6 (SUPPL.). 1995. 8A. ISSN: 1059-1524, November 1995 (1995-11-01), XP000673051 *
WALENSKY L D ET AL: "Two novel families of odorant receptors are expressed in rat spermatids.", ANNUAL MEETING OF THE 6TH INTERNATIONAL CONGRESS ON CELL BIOLOGY AND THE 36TH AMERICAN SOCIETY FOR CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, USA, DECEMBER 7-11, 1996. MOLECULAR BIOLOGY OF THE CELL 7 (SUPPL.). 1996. 638A. ISSN: 1059-1524, December 1996 (1996-12-01), XP000673052 *

Also Published As

Publication number Publication date
AU1118197A (en) 1997-05-29
WO1997017444A2 (en) 1997-05-15

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