WO1997017437A3 - A chromosome 21 - derived nucleic acid encoding a novel protein, compositions and method using same - Google Patents

A chromosome 21 - derived nucleic acid encoding a novel protein, compositions and method using same Download PDF

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Publication number
WO1997017437A3
WO1997017437A3 PCT/US1996/017989 US9617989W WO9717437A3 WO 1997017437 A3 WO1997017437 A3 WO 1997017437A3 US 9617989 W US9617989 W US 9617989W WO 9717437 A3 WO9717437 A3 WO 9717437A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
chromosome
nucleic acid
same
acid encoding
Prior art date
Application number
PCT/US1996/017989
Other languages
French (fr)
Other versions
WO1997017437A2 (en
Inventor
Julie R Korenberg
Kazuhiro Yamakawa
Original Assignee
Cedars Sinai Medical Center
Julie R Korenberg
Kazuhiro Yamakawa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cedars Sinai Medical Center, Julie R Korenberg, Kazuhiro Yamakawa filed Critical Cedars Sinai Medical Center
Publication of WO1997017437A2 publication Critical patent/WO1997017437A2/en
Publication of WO1997017437A3 publication Critical patent/WO1997017437A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides isolated nucleic acids encoding human EHOC-17 protein and isolated EHOC-17 proteins encoded thereby. Further provided are vectors containing invention nucleic acids, probes that hybridize thereto, host cells transformed therewith, antisense oligonucleotides thereto and compositions containing antibodies that specifically bind to invention polypeptides, as well as transgenic non-human mammals that express the invention protein.
PCT/US1996/017989 1995-11-10 1996-11-08 A chromosome 21 - derived nucleic acid encoding a novel protein, compositions and method using same WO1997017437A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US645395P 1995-11-10 1995-11-10
US60/006,453 1995-11-13
US08/745,956 1996-11-07

Publications (2)

Publication Number Publication Date
WO1997017437A2 WO1997017437A2 (en) 1997-05-15
WO1997017437A3 true WO1997017437A3 (en) 1997-08-28

Family

ID=21720971

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/017989 WO1997017437A2 (en) 1995-11-10 1996-11-08 A chromosome 21 - derived nucleic acid encoding a novel protein, compositions and method using same

Country Status (1)

Country Link
WO (1) WO1997017437A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI973762A0 (en) 1997-09-23 1997-09-23 Krohn Kai Ny gen
LU90406B1 (en) 1999-06-21 2000-12-22 Wurth Paul Sa Liquid pig iron production process

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021252A2 (en) * 1994-02-01 1995-08-10 The Board Of Trustees Of The Leland Stanford Junior University Wd-40-derived peptides and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021252A2 (en) * 1994-02-01 1995-08-10 The Board Of Trustees Of The Leland Stanford Junior University Wd-40-derived peptides and uses thereof

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
CHEN, H.M., ET AL .: "UNPUBLISHED", EMBL SEQUENCE DATA LIBRARY, 18 July 1996 (1996-07-18), HEIDELBERG, GERMANY, XP002031436 *
CHUMAKOV,I., ET AL.: "CONTINUUM OF OVERLAPPING CLONES SPANNING THE ENTIRE HUMAN CHROMOSOME 21Q", NATURE, vol. 359, 1 October 1992 (1992-10-01), pages 380 - 387, XP002031438 *
HILLIER, L., ET AL .: "THE WASHU-MERCK EST PROJECT", EMBL SEQUENCE DATA LIBRARY, 1 July 1995 (1995-07-01), HEIDELBERG, GERMANY, XP002031432 *
HILLIER,L., ET AL.: "THE WASHU-MERCK EST PROJECT", EMBL SEQUENCE DATA LIBRARY, 23 April 1995 (1995-04-23), HEIDELBERG, GERMANY, XP002031433 *
LAFRENIÈRE, R.G.,ET AL.: "ISOLATION AND GENOMIC STRUCTURE OF A HUMAN HOMOLOG OF THE YEAST PERIODIC TRYPTOPHAN PROTEIN 2 (PWP2) GENE MAPPING TO 21Q22.3", GENOME RESEARCH, vol. 6, December 1996 (1996-12-01), pages 1216 - 1226, XP002031440 *
LALIOTI, M.D., ET AL.: "CLONING THE cDNA OF HUMAN PWP2, WHICH ENCODES A PROTEIN WITH WD REPEATS AND MAPS TO 21q22.3", GENOMICS, vol. 35, no. 2, 15 July 1996 (1996-07-15), pages 321 - 327, XP000673975 *
LALIOTI,M.D., ET AL .: "UNPUBLISHED", EMBL SEQUENCE DATA LIBRARY, 18 July 1996 (1996-07-18), HEIDELBERG, GERMANY, XP002031434 *
LEHESJOKI, A-E., ET AL .: "LOCALIZATION OF THE EPM1 GENE FOR PROGRESSIVE MYOCLONUS EPILEPSY ON CHROMOSOME 21: LINKAGE DISEQUILIBRIUM ALLOWS HIGH RESOLUTION MAPPING", HUMAN MOLECULAR GENETICS, vol. 2, no. 8, 1993, pages 1229 - 1234, XP002031439 *
YAMAKAWA, K., ET AL .: "A PERIODIC TRYPTOPHAN PROTEIN 2 GENE HOMOLOGUE (PWP2H) IN THE CANDIDATE REGION OF PROGRESSIVE MYOCLONOUS EPILEPSY ON 21q22.3", CYTOGENETICS AND CELL GENETICS, vol. 74, 1996, pages 140 - 145, XP000673963 *
YAMAKAWA, K., ET AL .: "HOLOPROSENCEPHALY: CHARACTERIZATION OF THE DELETION OF 21q22.3 AND ISOLATION OF cDNAs BY A DIRECT SELECTION TECHNIQUE", THE AMERICAN JOURNAL OF HUMAN GENETICS, vol. 55, no. 3, September 1994 (1994-09-01), pages 1608, XP000673898 *
YAMAKAWA, K., ET AL .: "UNPUBLISHED", EMBL SEQUENCE DATA LIBRARY, 16 September 1996 (1996-09-16), HEIDELBERG, GERMANY, XP002031435 *

Also Published As

Publication number Publication date
WO1997017437A2 (en) 1997-05-15

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