WO1997006807A3 - Kombinationspräparat zur kontrazeption, kits diese enthaltend und eine methode diese verwendend - Google Patents

Kombinationspräparat zur kontrazeption, kits diese enthaltend und eine methode diese verwendend Download PDF

Info

Publication number
WO1997006807A3
WO1997006807A3 PCT/EP1996/003602 EP9603602W WO9706807A3 WO 1997006807 A3 WO1997006807 A3 WO 1997006807A3 EP 9603602 W EP9603602 W EP 9603602W WO 9706807 A3 WO9706807 A3 WO 9706807A3
Authority
WO
WIPO (PCT)
Prior art keywords
combined preparation
contraceptive
phase
same
kits containing
Prior art date
Application number
PCT/EP1996/003602
Other languages
English (en)
French (fr)
Other versions
WO1997006807A2 (de
Inventor
Klaus Stoeckemann
Ulrich Koch
Kristof Chwalisz
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Priority to JP9508949A priority Critical patent/JPH11511157A/ja
Priority to EP96928467A priority patent/EP0844880A2/de
Priority to AU68217/96A priority patent/AU6821796A/en
Publication of WO1997006807A2 publication Critical patent/WO1997006807A2/de
Publication of WO1997006807A3 publication Critical patent/WO1997006807A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Die vorliegende Erfindung betrifft ein mehrphasiges Kombinationspräparat, enthaltend mindestens 28 tägliche Dosierungseinheiten: mit einer ersten Phase von mindestens 21 ersten täglichen Dosierungseinheiten, enthaltend einen kompetitiven Progesteronantagonisten in einer Dosierung, die die Ovulation während der ersten eben benannten Phase hemmt; und einer zweiten Phase von 5 bis 28 täglichen Dosierungseinheiten, worin jede Dosierungseinheit dieser zweiten Phase ein Gestagen enthält, sowie eine entsprechende, dieses Kombinationspräparat enthaltende Packung (kontrazeptionelles Kit) und eine kontrazeptive Methode, die sich des vorstehenden Kombinationspräparates bedient.
PCT/EP1996/003602 1995-08-17 1996-08-16 Kombinationspräparat zur kontrazeption, kits diese enthaltend und eine methode diese verwendend WO1997006807A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP9508949A JPH11511157A (ja) 1995-08-17 1996-08-16 避妊用複合調剤、複合調剤を含有するキット及び複合調剤の使用方法
EP96928467A EP0844880A2 (de) 1995-08-17 1996-08-16 Kombinationspräparat zur kontrazeption, kits diese enthaltend und eine methode diese verwendend
AU68217/96A AU6821796A (en) 1995-08-17 1996-08-16 Contraceptive combined preparation, kits containing the same and contraceptive method using this combined preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19531936A DE19531936A1 (de) 1995-08-17 1995-08-17 Kombinationspräparat zur Kontrazeption, Kits diese enthaltend und eine Methode diese verwendend
DE19531936.2 1995-08-17

Publications (2)

Publication Number Publication Date
WO1997006807A2 WO1997006807A2 (de) 1997-02-27
WO1997006807A3 true WO1997006807A3 (de) 1997-03-20

Family

ID=7770785

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/003602 WO1997006807A2 (de) 1995-08-17 1996-08-16 Kombinationspräparat zur kontrazeption, kits diese enthaltend und eine methode diese verwendend

Country Status (7)

Country Link
US (1) US20050064031A1 (de)
EP (1) EP0844880A2 (de)
JP (1) JPH11511157A (de)
AU (1) AU6821796A (de)
DE (1) DE19531936A1 (de)
WO (1) WO1997006807A2 (de)
ZA (1) ZA966995B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5898032A (en) 1997-06-23 1999-04-27 Medical College Of Hampton Roads Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy
JP2007197459A (ja) * 1997-06-23 2007-08-09 Duramed Pharmaceuticals Inc 月経の出血を少なくし維持された効力を持つ超低投与量避妊薬
NZ504351A (en) * 1997-11-14 2002-10-25 Akzo Nobel Nv Contraceptive kit comprising progestogen and anti-progestogen and use in treating bleeding induced by a progestogen-only contraceptive regimen
SI1453521T1 (sl) 2001-12-05 2013-11-29 Teva Women's Health, Inc. Oralni kontraceptiki za preprečevanje nosečnosti in zmanjševanje predmenstrualne simptomatike
US7099318B2 (en) 2001-12-28 2006-08-29 Intel Corporation Communicating message request transaction types between agents in a computer system using multiple message groups
RU2403046C2 (ru) * 2003-07-16 2010-11-10 Тева Вимен'С Хелс, Инк. Способы гормонального лечения с применением контрацептивных режимов с непрерывным введением эстрогена
US20070111975A1 (en) 2004-10-07 2007-05-17 Duramed Pharmaceuticals, Inc. Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens
ES2558030T3 (es) * 2006-03-02 2016-02-01 Warner Chilcott Company, Llc Método anticonceptivo oral multifásico de ciclo prolongado
US20100178323A1 (en) 2007-07-10 2010-07-15 Agis Kydonieus Dermal Delivery Device
CA2740004A1 (en) 2008-10-08 2010-04-15 Agile Therapeutics, Inc. Transdermal delivery
US9198876B2 (en) 2008-10-08 2015-12-01 Agile Therapeutics, Inc. Contraceptive transdermal delivery of hormones
ES2795455T3 (es) 2008-10-08 2020-11-23 Agile Therapeutics Inc Suministro transdérmico
WO2010111488A1 (en) 2009-03-27 2010-09-30 Agile Therapeutics, Inc. Transdermal delivery

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017686A1 (en) * 1992-03-02 1993-09-16 Schering Aktiengesellschaft Estrogen/progestin/antiprogestin method and kit for oral contraception and regulating menses
DE4344405A1 (de) * 1993-12-24 1995-06-29 Marika Dr Med Ehrlich Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption
DE4344463A1 (de) * 1993-12-22 1995-06-29 Schering Ag Kombinationsprodukt zur Kontrazeption
DE4426601A1 (de) * 1994-07-27 1996-02-01 Schering Ag Verwendung eines Kombinationsproduktes enthaltend einen kompetitiven Progesteronantagonisten und ein Gestagen zur Herstellung eines Arzneimittels zur Behandlung der Endometriose oder des Leiomyomata uteri
WO1996015794A1 (en) * 1994-11-22 1996-05-30 Balance Pharmaceuticals, Inc. Compositions and methods for contraception and for treatment of benign gynecological disorders

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017686A1 (en) * 1992-03-02 1993-09-16 Schering Aktiengesellschaft Estrogen/progestin/antiprogestin method and kit for oral contraception and regulating menses
DE4344463A1 (de) * 1993-12-22 1995-06-29 Schering Ag Kombinationsprodukt zur Kontrazeption
DE4344405A1 (de) * 1993-12-24 1995-06-29 Marika Dr Med Ehrlich Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption
DE4426601A1 (de) * 1994-07-27 1996-02-01 Schering Ag Verwendung eines Kombinationsproduktes enthaltend einen kompetitiven Progesteronantagonisten und ein Gestagen zur Herstellung eines Arzneimittels zur Behandlung der Endometriose oder des Leiomyomata uteri
WO1996015794A1 (en) * 1994-11-22 1996-05-30 Balance Pharmaceuticals, Inc. Compositions and methods for contraception and for treatment of benign gynecological disorders

Also Published As

Publication number Publication date
WO1997006807A2 (de) 1997-02-27
EP0844880A2 (de) 1998-06-03
ZA966995B (en) 1997-11-04
DE19531936A1 (de) 1997-02-20
JPH11511157A (ja) 1999-09-28
US20050064031A1 (en) 2005-03-24
AU6821796A (en) 1997-03-12

Similar Documents

Publication Publication Date Title
AU8967991A (en) Contraceptive regimen
FI99083B (fi) Matalaestrogeenisia oraalisia raskaudenehkäisyvalmisteita
WO1997006807A3 (de) Kombinationspräparat zur kontrazeption, kits diese enthaltend und eine methode diese verwendend
CA2135608A1 (en) Contraception using competitive progesterone antagonists, and novel compounds useful therefor
AU3436097A (en) Progestogen-anti-progestogen regimens
WO1999012531A3 (de) Mittel zur hormonalen kontrazeption
PT735882E (pt) Combinacao contraceptiva contendo antagonistas de progesterona e um progestogeno
CA2225724A1 (en) Pharmaceutical combined preparation, kit and method for hormonal contraception
NL300381I2 (nl) Estradiolvaleraat en dienogest
EP0402950A3 (de) Behandlung von Störungen in der Postmenopause
UA41401C2 (uk) Фармацевтичний контрацептивний комбінований препарат
IL104915A0 (en) Pharmaceutical composition containing estrogen,progestin and antiprogestin and kits containing the same
BG104451A (en) Antiestrogen and progestin-containing peroral contraceptives
CA2057714A1 (en) Progestagen-only contraceptive
CA2131911A1 (en) Minimizing progestin associated breakthrough bleeding
BG101427A (en) Competitive progesterone antagonists for regulating female fertility as required
ATE249222T1 (de) Biphasische orale verhuetungsmethode und kit die eine kombination von progestin und eines oestrogens enthalten
NZ504351A (en) Contraceptive kit comprising progestogen and anti-progestogen and use in treating bleeding induced by a progestogen-only contraceptive regimen
WO1999051214A3 (en) Progestogen-only contraceptive kit
CA2248841A1 (en) Sequential oestrogen/progesterone antagonist combination for hormone replacement therapy
UA41351C2 (uk) Спосіб контрацепції та набір таблеток
Nieman ENDOMETRIAL EFFECTS OF RU 486 IN NORMALLY CYCLING WOMEN MAY OFFER NEW CONTRACEPTIVE STRATEGIES.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU BR BY CA CN CZ EE HU IL IS JP KR LT LV MX NO NZ PL RU SI SK UA VN

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

AK Designated states

Kind code of ref document: A3

Designated state(s): AU BR BY CA CN CZ EE HU IL IS JP KR LT LV MX NO NZ PL RU SI SK UA VN

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1996928467

Country of ref document: EP

ENP Entry into the national phase

Ref country code: JP

Ref document number: 1997 508949

Kind code of ref document: A

Format of ref document f/p: F

WWP Wipo information: published in national office

Ref document number: 1996928467

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: CA

WWW Wipo information: withdrawn in national office

Ref document number: 1996928467

Country of ref document: EP