WO1997000017A1 - Complement nutritionnel - Google Patents

Complement nutritionnel Download PDF

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Publication number
WO1997000017A1
WO1997000017A1 PCT/US1995/008470 US9508470W WO9700017A1 WO 1997000017 A1 WO1997000017 A1 WO 1997000017A1 US 9508470 W US9508470 W US 9508470W WO 9700017 A1 WO9700017 A1 WO 9700017A1
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WO
WIPO (PCT)
Prior art keywords
animal
metabolic
corrector
metabolic corrector
yeast
Prior art date
Application number
PCT/US1995/008470
Other languages
English (en)
Inventor
Carlos Roberto Protti
Original Assignee
Quinonez-Meza, Fernando
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US08/261,134 priority Critical patent/US5536509A/en
Priority claimed from US08/261,134 external-priority patent/US5536509A/en
Application filed by Quinonez-Meza, Fernando filed Critical Quinonez-Meza, Fernando
Priority to BR9510613-8A priority patent/BR9510613A/pt
Priority to PCT/US1995/008470 priority patent/WO1997000017A1/fr
Priority to CA002224568A priority patent/CA2224568A1/fr
Publication of WO1997000017A1 publication Critical patent/WO1997000017A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry

Definitions

  • This invention relates to nutritional supplements for livestock. More specifically, the invention relates to a combination of Macrocystis algae, yeast, calcite, and other minerals, and methods of supplementing animal feed to promote growth and productivity.
  • U.S. patent no. 5,211,980 discloses a lipid pellet having an algin component such as sodium alginate and other nutritive elements.
  • the prior art does not include a combination of natural components including
  • Macrocystis algae, yeast, and calcite that is adjusted to the needs of a particular type of livestock, and provides excellent growth and performance.
  • a nutritional supplement according to the invention is prepared from algae, yeast, and a mineral component.
  • the supplement acts as a metabolic corrector and improves the health and growth of dairy and beef cattle, horses, and chickens, and improves milk and egg production.
  • Minerals and vitamins may be added to the supplement where desired to counteract metabolic deficiencies in the animal.
  • a nutritional supplement for animals contains Macrocystis algae meal, dry yeast, and a mineral component.
  • the algae is dried and crushed to a meal
  • the yeast is Cepa Sc in microcapsules
  • the mineral component is powdered calcite from sea shells.
  • the Macrocystis algae comprises about 25- 75% by weight
  • the yeast comprises about 10-50% by weight
  • the powdered calcite comprises about 10-30% by weight.
  • the Macrocystis algae comprises about 50% by weight
  • the yeast comprises about 30% by weight
  • the powdered calcite comprises about 20% by weight.
  • the invention also comprises a method of improving the health of an animal comprising combining crushed calcite with Macrocystis algae meal and microcapsulated yeast to provide a nutritional supplement, and feeding the supplement to the animal.
  • the method may also comprise (a) measuring metabolite levels in a stable tissue of the animal; (b) identifying metabolites whose levels are lower than desired; (c) adding the identified metabolites to crushed calcite; (d) combining the calcite with Macrocystis algae meal and microcrystalline yeast to provide a nutritional supplement; and (e) feeding the supplement to the animal.
  • the method preferably involves providing the supplement in an amount of about 0.1 g to 1.0 g per kg body weight.
  • the metabolic corrector has other beneficial applications. It can prevent and treat viral infections in animals, particularly poultry, when a therapeutically effective dose of a
  • combination of the metabolic corrector is administered orally. It can also promote physical and mental health in humans.
  • FIG. 1 illustrates milk production records for dairy cattle fed with the metabolic corrector as compared to controls.
  • Fig. 2 illustrates milk fat content for dairy cattle fed with the metabolic corrector compared to controls.
  • the metabolic corrector is prepared from three basic ingredients. Other minerals and supplements may be added according to the specific needs of particular animals.
  • the metabolic corrector is preferably made up as follows:
  • yeast culture preferably a live yeast such as Cepa Sc 47 in microcapsules - about 10-50% by weight, preferably about 30%;
  • calcite preferably from pulverized sea shells, as an excipient - about 10-30% by weight, preferably about 20%.
  • a preferred dosage is about 0.1 to about 1 gram per kg live weight of the animal in question, most preferably about 0.25 grams per kg. Other amounts, lower or higher, may be desirable depending on the animals' particular needs.
  • the metabolic corrector typically comprises about 85% dry matter and about 15% water. These proportions may vary depending on climate and storage conditions. It is typically fed dry, but may be added to warm water for consumption, in which case it forms a viscous, gelatinous preparation.
  • Mineral elements may be added to the calcite excipient as indicated in each case depending on the nutritional requirements of the animal.
  • the calcite component generally contains substantial amounts of calcium, sodium, phosphorous, potassium, magnesium, and sulfur.
  • Other minerals in the excipient may include cobalt, silver, boron, bromine, chromium, copper, iron, iodine, mangasese, molybdenum, nickel, strontium, vanadium, and zinc.
  • slow growing animal tissue such as poultry feathers, hair, hoof, or blood are sampled and analyzed by an assay for mineral content.
  • the quantities of these elements are determined in each particular case by an analysis of blood, hair or feather samples.
  • the qualitative and quantitative mineral content of the sampled tissues are compared to a standard source, such as the U.S. Department of Agriculture Minimum Daily Requirement Tables for the particular species, referred to as Cantidad Suficiente Para 100, or quantity sufficient to reach 100% of the desired level, by weight or volume. If the level of a particular mineral in a test animal is below the recommended level, then an extra quantity of that mineral is added to the calcite excipient as a supplement to meet the animal's minimum requirements.
  • the supplemental minerals are easily obtainable anywhere in the world without restriction.
  • the metabolic corrector in proportions adequate to each animal species in general optimizes the utilization of the available nutrients and coenzymes in the feed ration vital to normal metabolism.
  • the metabolic corrector apparently acts as a nutritional "buffer,” and allows for the adequate abso ⁇ tion of the metabolites in the feed ration, i.e., glucids, proteins (amino acids), vitamins, and macro and microelements.
  • the metabolic corrector of the invention has been found to have many beneficial effects with various animals. These benefits are described here in terms of numerical observations made during the course of recent experimental procedures.
  • Ruminants more often than not present digestive disturbances as a result of man's constant interference in their feed formulation. This exposes the milking cow to nutritional factors and conditions which tend to limit optimum milk production and often is the cause for toxic and semi-toxic levels of certain elements.
  • the interaction of the metabolic corrector in the ruminal medium modifies the metabolism of the intestinal flora. This interaction increases the pH of the digestive medium to 6.9, a level which is considered to be normal.
  • Cows under pasture feeding conditions tend to have a ruminal pH in the order of 5.9/6.2.
  • This acid ruminal medium causes an alteration of the ruminal flora and therefore an alteration of the metabolic process with special emphasis on proteins.
  • Approximately 80% of the protein in the ration is broken down in the rumen, and through the cellulitic (or cellular) action of the flora, is converted into bacterial protein.
  • the undigested protein is transformed into ammonia (hepatotoxic ammonia).
  • ammonia overtaxes the liver as ammonia is absorbed through the walls of the rumen in transit to the circulatory system. These conditions result in a loss of protein in the diet and predominant toxic state in the animal.
  • the optimum ammonia concentration content for an acceptable protein metabolism is in the order of 5 grams per every 100 milliliters
  • Cows in the above examples have been found to have levels of 30 to 40 grams per 100 milliliters of ruminal fluid.
  • the metabolic corrector When the metabolic corrector is added to the daily ration, in an amount of about 100 grams per day for a cow of 1,100 lbs. live weight, after a period of time, the pH becomes adjusted to a desirable level. Thereafter, bacteria and protozoans will function adequately in the breakdown of proteins thereby reducing the levels of ammonia and thus increasing bacterial protein.
  • Protein content increases from 3 to 5 % .
  • Sporting horses often live in an artificial environment (a box), with little or no light and are fed a ration which is brought by man. Generally horses under this medium live under a permanent state of stress. This medium often results in lack of appetite (anorexia); disturbances in the color and odor of the fecal matter; and exposure to colic. It is commonly observed, when exposed to a competitive environment, that these animals show a general lack of appetite and stress.
  • the use of the metabolic corrector in the ration results in a stabilization of the digestive process as shown in the normalization of the fecal matter, an increase in appetite shown under voluntary feeding and better performance under a training environment.
  • Vitamins (in Milligrams per Kg. Drv Matter)
  • the amounts of these components may vary. However, it is important that the algae, yeast, and calcite components of the metabolic corrector be used in their essentially intact form. For example, a synthetic combination of the analytically determined components of Component A does not achieve the results claimed heretofore. Likewise, the use of less than all three of the ingredients of the metabolic corrector may be beneficial but does not provide the optimal results according to the invention. Preferably, the algae, yeast, and calcite must all be present together to provide the su ⁇ rising effectiveness of the metabolic corrector.
  • the genus Macrocystis is the largest algae in the family Lessoniaceae . It includes M. pyrifera L., M. integrifolia Bory, and M. angustifolia Bory. M. pyrifera is preferred, although
  • Algaes of related genuses include Dictyoneurum, Pelagophycus, and Nereocystis.
  • the blades of the algae are the preferred components, although the entire plant may be used.
  • EXAMPLE 1 An experiment was conducted with cattle to determine whether the metabolic corrector provided a marked improvement in the general metabolism (specifically in the ruminal metabolism) of cattle through the use of human medical techniques, thereby improving the production of beef and milk.
  • the specific objective of the experiment was to determine the correction of the digestive media through the use of diagnosed metabolic correctors in a milking herd in Argentina.
  • the breed of cattle was Holstein Fresian cows.
  • the process of selection of the Test Group was based on the diagnosis of existing needs in the herd at a time where maximum milk production was required. This period, between 0 to 90 days after calving, demands from the cow the use of all of its reserves to meet the highest nutritional requirements imperative at the time of maximum lactation.
  • the diagnostic process began with the extraction of serum and blood samples from each individual animal. These samples provided a mineral content profile for each individual Group at the onset of the experience. The minerals tested were those considered most lacking in the region. These minerals are: Calcium (Ca); Phosphorus (P); Magnesium (Mg); and Copper (Cu) as well as Total Protein and Albumin.
  • a metabolic corrector was prescribed for the test herd in view of this diagnosis and taking into consideration the lactating period previously mentioned. The same formulation was used for all the cows in the test group. This metabolic corrector was fed twice a day at a rate of 100 grams/animal/day. The amount of metabolic corrector fed (100 grams/animal/day) remained the same any time that the feed quantity was either changed or modified thus establishing a new relationship between the feed ration and the corrector. Feed Management
  • Pasture time on a daily rotating basis was set from 0800-1500 hrs - then milking; and from 1800-0400 hrs. - then milking. As of December 30th, 1992 the Groups were put into pens at night where good quality hay was provided after pasturing on grass.
  • the grazing sequence is shown in Table 1.
  • the feed plants found in the Argentinean pastures are as follows:
  • Trebol Rojo - Red Clover (trifolium pratensis)
  • Pasto Ovillo - Sheep Grass (dactylis glomerata)
  • Sorgo Forrajero - Sorgum (sorgum sacaratum)
  • Agropiro (agrophrum alongatum) Melilotus - Lotus (mililotus officinalis) Moha de Hungria (satarea italium pratensis) Phalaris (phalaria bulbosa)
  • Table "2" provides a comparison of Milk Production in the "Test Group, " the "Control Group” as well as the whole of the milking herd.
  • a graph is provided as Fig. 1.
  • Cows were not given their feed rations from Dec. 9 through Dec. 12, 1992.
  • Table "4" provides a comparison in Milk Fat Content for the "Test Group,” the "Control Group” as well as the whole of the milking herd. A graph depicting these quantities is also provided as Fig. 2.
  • test animals were slightly lighter, on average, than the control group, but they were otherwise comparable.
  • the average weights of the animals at the beginning of the experiment is shown in Table 5.
  • the invention uses natural elements in essentially intact form (high concentration kelp, dried and crushed; live yeast in microcapsules; supplemented by calcite).
  • the specification does not call for subjecting these components to heat, which would kill the yeast and alter the intact form of the algae.
  • the metabolic corrector works as a nutritional "buffer" and allows for adequate absorption of the metabolites in the feed ration.
  • the constituents of the metabolic corrector are provided in their natural form, essentially intact, not as a consequence of exposure to high temperatures.
  • the metabolic corrector is comprised of certain substances that once introduced in the digestive system, are highly synergistic on the components thereof, the results of which are reflected in the animal's optimized health, a better assimilation of nutrients, higher production efficiency and natural augmentation of the immune system action of each species.
  • the metabolic corrector is not a mere nutrient source. It is not a feed in itself but is added to animal feeds. It is comprised of natural substances which, in essentially intact form and in certain quantities, help in the metabolic processes of animals, allowing regulation of digestion physiology, such as pH levels in ruminants. Within the organism, at bodily temperature, the metabolic corrector achieves remarkable increases in the animal's productive response, presumably due to improved absorption of essential nutrients, stabilizing changes in elements, micro elements and metabolites in general. When trace elements in animal feeds are taken via the intestinal mucous membrane and absorbed into the blood stream, they join with carrier proteins (apoenzymes) which provide the cells with the metals and nutrients required for metabolism, and may be stored in the liver.
  • carrier proteins apoenzymes
  • the composition of the invention is not a mere nutrient source or feed but a metabolic corrector that is added to animal feeds. It helps in the metabolic processes of animals, allowing regulation of digestion physiology. Within the organism, at bodily temperature, it achieves enhance absorption of essential nutrients, stabilizes changes in elements, microelements and metabolites in general, and is therefore highly beneficial for the animal by holistic criteria. It also allows remarkable increases in the animal's productivity (eupeptic action).
  • the product can regulate pH levels like a buffer) .
  • a preferred embodiment comprises;
  • the invention employs holistic principles of medicine (the whole animal system is analyzed and not a specific organ).
  • the gastrointestinal medium serves as fermentation vessel where nutrients are naturally supplied and released and where microorganisms are freely reproduced (living yeasts) .
  • microorganisms are freely reproduced (living yeasts) .
  • the kelp is believed to serve as a substrate or "culture medium" within the animal itself, so that living, high concentration yeast may fully develop its fermentation power.
  • the dried kelp hydrates and due to moisture and bodily temperature and the agar nature thereof, forms a viscous gel, a colloidal suspension of mucopolysaccharides, so that the composition may slowly release natural components (vitamins, proteins, carbohydrates, aminoacids, minerals and trace elements or coenzymes) .
  • the kelp is believed to act as a chelating agent (a phycocolloid) , improving bioavailability of e.g. minerals, trace elements, carbohydrates, vitamins, and coenzymes.
  • Algae have a large content of polyunsaturated fats, i.e. palmitic, stearic, miristic, agraquidonic, linolenic, gamma-linolenic (Henrikson) .
  • These essential fatty acids (EFA) have multiple actions e.g.: they help normalize cholesterol levels; they are forerunners of prostaglandins; and they retard premature aging processes. High concentration, living yeast is used (probiotic).
  • the AAFCO essential fatty acids
  • yeast cultures as a dry product of living yeast and medium retaining fermentation power.
  • Microencapsulated yeast has important benefits: the yeast reaches the digestive system intact.
  • the yeast used according to the invention is dry but it is preferably live, active, latent yeast and it keeps its power to ferment unlike feed or brewer's yeasts that are inactive.
  • One commercially available example comprises yeast cultivated in a substrate of sugar cane syrup which is used to encapsulate the living yeast.
  • the active substance is comprised of viable cells of Saccharomyces cerevisiae, SC 47 Strain.
  • This example is High Concentration Yeast, Biosaf SC 47 available from Societe Industrielle Lessaffre, Marcq-En-Baroeul-France.
  • This type of living, high concentration yeast contains 5x10' living cells per gram.
  • Other types of living, high concentration yeast may be used if they have the necessary latency from microencapsulation and fermentation power.
  • the process to dry living high concentration yeasts is carried out at temperatures not higher than about 50° C, preferably below about 30° C.
  • yeast in fermentation in the animal with the culture medium of algae as support causes stimulation and supply of nutrients to the normal microflora and the conversion of non proteinic nitrogen, specifically ammonia, NH3, into bacterial proteins of high biological value.
  • Calcite is beneficial both because it provides its own components and is a micronutrient excipient.
  • An excipient is an inert substance used for combining with a drug for desired bulk, taste, or other characteristics to simplify its use.
  • Standard methods of detecting nutritional deficiencies rely on blood mineral profiles.
  • a bloodprofile is only an instantaneous photograph; the values obtained depend on the intake composition at that precise momentand and may vary if time elapses from such intake.
  • blood composition is not the same if tested during fast or after a big meal. Metabolite levels in both samples vary. Accordingly, a test was needed that allows analysis of the "mineral history" of the animal.
  • the mineralogram according to the invention may be a hair, feather, hoof, or nail test. This makes it possible to detect the effect of factors external to the organism (toxic minerals, nourishment, climate, captivity, etc.) which may influence future productivity.
  • sea calcite may be used to contain and transport micro and macro minerals included in the formulation for each species.
  • the invention uses the diqestive system as a path and the animal feed as a carrier to introduce the product into the gastrointestinal system, where natural seaweeds act as a culture medium and nutrient supply, causing the gel or colloid formed with the digestive system fluids (moisture) at bodily temperature to develop and living yeast to multiply. Simultaneously, a series of important interactions, reactions and metabolite release begins to take place in the digestive system.
  • the algae form a viscous gel when the product contacts gastric juices; this enhances reproduction of living yeast, slowly releasing the components thereof, in conjunction with calcite, which helps regulate pH levels and delivers micronutrients. Industrial processing is not needed to cause the desired effects.
  • the product has eupeptic action, as a drug that improves food digestion and increases hunger, and a eutrophic action, as it induces the animal to build biomass with abundant nutrients.
  • MANUFACTURING The three basic components, in the quantity desired, are placed in a regular mixer (as typically usually used in feed factories). The preparation should be mixed for about 30 minutes to attain a homogenous mixture, and then is turned into powder pellets. Once the mixing process is completed, the product is packed in containers such as cardboard, two-ply paper sacks, or polypropylene. Preferably, the part of the container which contacts the product should be water-resistant for better preservation, since the final product is hygroscopic ("absorbing or attracting moisture from the air according to environmental conditions"). Once the product is packed, it should be stored in dry, closed places, at ambient temperature below about 50° C. The finished and presented product is ready to be added to animal feeds per use and quantity instructions.
  • flavorings can be added to the product to obtain better acceptance by the animal under treatment (for example: honey or apple flavorings for swine and garlic flavorings for dogs).
  • honey or apple flavorings for swine and garlic flavorings for dogs As flavorings are used in small quantities, same should be previously "stretched" with one of the components of the product (for example, calcite).
  • Phase II In monogastric animals, the metabolic corrector is ingested and, after the inherent process of chewing and primary enzymatic action, it is then subjected to further bacterial and protozoogenic action (with pepsins and stomach hydrochloric acids coming in to play) and thus the biodegradation of the ingested foods begins to take effect. Polygastric animals (ruminants) further subject the ingested feed to normal digestive floral action as well as the mechanical (pressing) action typical of the polygastric stomach.
  • Regurgitation occurs as part of the normal ruminant process with consequent ingestion into the obomassums where the feed bolus is further subjected to the action of the digestive juices.
  • the composition is subjected to both bacterial and enzymatic action.
  • the corrector Upon being ingested, the corrector is subjected to hydration at rumen temperature (37° C).
  • the live yeast emerge from their latent state and begin to perform those (eupeptic) actions contributing to improved digestion and metabolic absorption of all available nutrients. This occurs basically through the utilization of non-proteinic nitrogen.
  • These ruminal processes end with the creation of volatile fatty and aminoacids i.e., acetic, butyric and propionic.
  • the NH3 is transformed into bacterial proteins of high biological value in the improvement of the animal's productivity.
  • the metabolic corrector also helps with breakdown of fiber.
  • Phase III Following the gastro-ruminal phase is the gastro-intestinal phase where pancreatic amylases, proteases and lipases, together with the detergent action of the liver bile subject the feed components as well as the corrector to further degradation. This is the end of the physical-chemical degradation process. Normal intestinal flora develops its own fermentation process. After routine use of the metabolic corrector has been established (15 to 20 days) this intestinal flora is believed to begin to attach itself to the cellular walls of the algae.
  • Edible algae used in the formulation of the invention live and reproduce in a marine environment and thus develop walls which are made of cellulose and lignin.
  • the surrounding environment where these algae prosper is of a lower temperature. This, together with the action of the sea and the rocks, call for a natural survival reaction from the algae resulting in the strengthening of these cellular walls.
  • Normal intestinal flora develop which attach themselves to these walls by cellulo-sicolitic action. This takes place during the period of 15 to 20 days mentioned above.
  • the feed and the metabolic corrector combined with body heat and ruminal humidity, and subjected to the processes described above, with the help of the agar, forms a colloidal suspension which attaches itself to the intestinal epithelial walls. It is here, in the intimate reaches of the capillary celiac, where the metabolic corrector is believed to release the carbohydrates, proteic amino acids, lipids, micro and macro minerals and vitamins to the circulatory system of the animal.
  • DOSAGE Medical technology and veterinary practice correlate dosage of elements to the weight of the individual. To obtain the recommended dosages a trial and error method can be used. Original dosages were based on clinical studies and results from mineral analysis of the individual or individuals. Beginning dosages were calculated to provide a metabolic correction. There were no negative adverse reactions to mega-doses, except perhaps a small laxative effect.
  • the metabolic corrector is used as a supplement for animal feeds, and is comprised of cold-dried Macrosystis Pyrifera algae, living high concentration yeast in the form of microcapsules and dried in the capsular medium, and calcite with mineral components pursuant to the requirements of each species.
  • the metabolic corrector is used in a process developed within the digestive system of the animal at bodily temperature with the algae as as culture medium; this interacts with and allows development of living, high concentration yeasts which, with calcite supplement, improves the development and use of minerals, carbohydrates, vitamins and trace elements.
  • the process of the invention uses the culture medium of the animal's digestive system, at bodily temperature, developed with Macrosystis algae, wherein living yeast cells reproduce "in situ". Metabolite measurement results are needed to prepare the combination required by each species.
  • the method of the invention improves the animal's health through enhanced nutrient release as a consequence of the interaction of Macrosystis algae, living, high concentration, encapsulated yeasts, and calcite. Practical experience with the metabolic corrector showed the following results:

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Abstract

Complément nutritionnel préparé à partir de farine d'algue de l'espèce Macrocystis, de microcapsules de levure et de calcite pulvérulente provenant de coquillages. Ce complément améliore l'état de santé et la croissance des bovins laitiers et à viande, des chevaux et des poulets, et améliore également la production de lait et d'oeufs. On peut adjoindre audit complément des minéraux et des vitamines lorsqu'il est désirable de traiter des carences métaboliques existant chez l'animal.
PCT/US1995/008470 1994-06-14 1995-06-14 Complement nutritionnel WO1997000017A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US08/261,134 US5536509A (en) 1994-06-14 1994-06-14 Metabolic corrector
BR9510613-8A BR9510613A (pt) 1995-06-14 1995-06-14 Suplemento nutricional
PCT/US1995/008470 WO1997000017A1 (fr) 1994-06-14 1995-06-14 Complement nutritionnel
CA002224568A CA2224568A1 (fr) 1994-06-14 1995-06-14 Complement nutritionnel

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/261,134 US5536509A (en) 1994-06-14 1994-06-14 Metabolic corrector
PCT/US1995/008470 WO1997000017A1 (fr) 1994-06-14 1995-06-14 Complement nutritionnel
CA002224568A CA2224568A1 (fr) 1994-06-14 1995-06-14 Complement nutritionnel

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WO1997000017A1 true WO1997000017A1 (fr) 1997-01-03

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PCT/US1995/008470 WO1997000017A1 (fr) 1994-06-14 1995-06-14 Complement nutritionnel

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1088483A1 (fr) * 1999-09-30 2001-04-04 Kleencare Hygiene GmbH Supplément alimentaire pour vaches laitières, veaux et génissons
WO2011098763A1 (fr) 2010-02-11 2011-08-18 Lidco Group Plc Moniteur hémodynamique et procédé de surveillance hémodynamique
US8519008B2 (en) 2003-01-22 2013-08-27 Purina Animal Nutrition Llc Method and composition for improving the health of young monogastric mammals
KR101833491B1 (ko) * 2017-06-27 2018-03-02 신승호 자이언트 켈프를 포함하는 기능성 사료 조성물 및 이를 이용한 가축의 사육방법
WO2019220052A1 (fr) 2018-05-15 2019-11-21 Lesaffre Et Compagnie Probiotique pour volaille ou ruminant
KR20200059724A (ko) * 2018-11-21 2020-05-29 한국프라임제약주식회사 괭생이모자반 추출박을 포함하는 면역증강용 사료첨가제 조성물 및 그 제조방법
US10905147B2 (en) 2016-12-30 2021-02-02 Patagonia Biotecnología S.A. Process for the preparation of an additive as a food supplement based on seaweeds for birds and animals; as well as the product obtained and its use in the food conversion and in the production of bird and animal meat

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876810A (en) * 1970-09-24 1975-04-08 Ocean Labs Kelp derived feeds containing sequestered trace minerals
US4087556A (en) * 1976-12-22 1978-05-02 Chemische Industrie Randstad, N.V. Folic acid animal feed materials and processes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876810A (en) * 1970-09-24 1975-04-08 Ocean Labs Kelp derived feeds containing sequestered trace minerals
US4087556A (en) * 1976-12-22 1978-05-02 Chemische Industrie Randstad, N.V. Folic acid animal feed materials and processes

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
C. GONZALEZ, BIOSIS PREVIEWS: 93060361, Cuban Journal of Agricultural Science, (1991) 25(1) 77-81. *
INTRODUCTION TO THE ALGAE: STRUCTURE AND REPRODUCTION, Second Edition, issued 1985, H.C. BOLD and M.J. WYNNE, "Division Phaeophyta", pages 365-374. *
L. HUSKIC, 921446661 CAB ABSTRACTS, Praxis Veterinaria (Zagreb), (1990) 38(2) 123-130. *
M. NADAADIN, 91-035645 AGRIS International, Veterinarski Glasnik, (1988) 42(9) 591-598. *

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* Cited by examiner, † Cited by third party
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EP1088483A1 (fr) * 1999-09-30 2001-04-04 Kleencare Hygiene GmbH Supplément alimentaire pour vaches laitières, veaux et génissons
US10172376B2 (en) 2003-01-22 2019-01-08 Purina Animal Nutrition Llc Methods for feeding sows and for improving the health of young piglets
US9078457B2 (en) 2003-01-22 2015-07-14 Purina Animal Nutrition Llc Method and composition for improving the health of young monogastric mammals
US9433232B2 (en) 2003-01-22 2016-09-06 Purina Animal Nutrition Llc Methods for feeding sows and for improving the health of young piglets
US8519008B2 (en) 2003-01-22 2013-08-27 Purina Animal Nutrition Llc Method and composition for improving the health of young monogastric mammals
US11452303B2 (en) 2003-01-22 2022-09-27 Purina Animal Nutrition Llc Methods for feeding sows and for improving the health of young piglets
US10980250B2 (en) 2003-01-22 2021-04-20 Purina Animal Nutrition Llc Methods for feeding sows and for improving the health of young piglets
WO2011098763A1 (fr) 2010-02-11 2011-08-18 Lidco Group Plc Moniteur hémodynamique et procédé de surveillance hémodynamique
US10188303B2 (en) 2010-02-11 2019-01-29 Lidco Group Plc Hemodynamic monitor and method of hemodynamic monitoring
US10905147B2 (en) 2016-12-30 2021-02-02 Patagonia Biotecnología S.A. Process for the preparation of an additive as a food supplement based on seaweeds for birds and animals; as well as the product obtained and its use in the food conversion and in the production of bird and animal meat
KR101833491B1 (ko) * 2017-06-27 2018-03-02 신승호 자이언트 켈프를 포함하는 기능성 사료 조성물 및 이를 이용한 가축의 사육방법
WO2019220052A1 (fr) 2018-05-15 2019-11-21 Lesaffre Et Compagnie Probiotique pour volaille ou ruminant
EP4413868A2 (fr) 2018-05-15 2024-08-14 Lesaffre et Compagnie Probiotique pour volaille
KR102122586B1 (ko) 2018-11-21 2020-06-15 한국프라임제약주식회사 괭생이모자반 추출박을 포함하는 면역증강용 사료첨가제 조성물 및 그 제조방법
KR20200059724A (ko) * 2018-11-21 2020-05-29 한국프라임제약주식회사 괭생이모자반 추출박을 포함하는 면역증강용 사료첨가제 조성물 및 그 제조방법

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