WO1996007447A1 - Drainage catheter for urinary neo-bladders - Google Patents

Drainage catheter for urinary neo-bladders Download PDF

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Publication number
WO1996007447A1
WO1996007447A1 PCT/IT1995/000143 IT9500143W WO9607447A1 WO 1996007447 A1 WO1996007447 A1 WO 1996007447A1 IT 9500143 W IT9500143 W IT 9500143W WO 9607447 A1 WO9607447 A1 WO 9607447A1
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
bladders
neo
continent
urinary
Prior art date
Application number
PCT/IT1995/000143
Other languages
French (fr)
Inventor
Mauro Dimitri
Original Assignee
Mauro Dimitri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mauro Dimitri filed Critical Mauro Dimitri
Priority to EP95930000A priority Critical patent/EP0751798A1/en
Priority to AU33754/95A priority patent/AU3375495A/en
Publication of WO1996007447A1 publication Critical patent/WO1996007447A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains

Definitions

  • Bladder trauma are also very frequent after a car crash,a working accident or other,and may require a cistectomy.
  • Two foundamental types of urinary neo-bladders allow the patient to achieve the urinary continence: the orthotopic neo-bladders where the patient voids through the penis, helping himself with the contraction of the abdominal musculature,and as in the normal condition the continence is achieved with the natural sfincter ; the neo-bladders with stoma in which the neo-bladder fashioned with a continence mechanism,is in communication with the abdominal wall,and the patient catheterizes himself through a stoma to void regularly.
  • the common post-operatory catheters utilized for the drainage of the neo-bladders are the same bladder catheters in use from many years to drain the natural bladder in several conditions(elderly condition,surgery of the
  • a bladder(urethral) catheter is usually made with different materials ( Latex Rubber,Polivinile,Poliurethane,Co-Polimer,Silicone Rubber, etc..) in different shapes and dimensions, has a large
  • the balloon that anchors the catheter is made of the same rubber-elastic material in different sizes and volumes,depending from the finalities,and can be inflated o deflated through a continent valve inserted
  • the tip of a bladder catheter is very short, beeng about 3 cm.
  • the intestinal mucosa is responsible of the frequent obstructions of the catheter by producing mucous secretions and mucous clots,with the risk of dangerous passive overdistensions of the neo-bladder just recently Q accomplished.
  • the nurse personnel and the doctors must frequently wash the neo-bladders through the catheter along the two weeks of post-operatory period.
  • the specific catheter I invented for neo-bladders can be utilized to prevent the mucous obstruction when an enlargement cistoplasty of the natural bladder is performed with a segment of intestine. This is obtained by the particular lenght of the tip, 5 anci for a different positioning of the balloon from the apex of the catheter.
  • the catheter is characterized by several holes along the tip of the catheter that allow a big surface of drainage;the catheter material warrants its
  • the Bladder catheters commonly in use have the tip, very short -measured from the distal end of the balloon to the apex of the catheter.
  • the catheter I invented,specially projected for urinary neo-bladders has a very long functioning tip, Q containing several holes to drain the urine and the mucous secretions produced by the mucosa of the intestine utilized in reconstructing the new bladder.
  • the holes along the common bladder catheters are usually only three.
  • the catheter I invented has several holes Q regularly placed along the two opposite sides of the tip in alternate fashion with the same diameter and distance one to each other side to side.
  • the catheter can be made with the Latex Rubber Hydrogel coated or with Silicone Rubber materials,both fused and shaped. If the catheter is made in Latex Rubber it is necessary, in order to improve its resistance to the incrustations and to improve a constant lubrification of the urethra for all the time in which the catheter is in place, that the catheter will be Hydrogel coated,a technique that in 2 commonly in use on other catheters from the market. If the catheter is made in silicone rubber,the catheter maintain more consistance and rigidity without loosing too much the elasticity,and also the silicone make the catheter resistant to the incrustations from mucous and from the erosion by the acid secretions from the stomach when utilized,allowing to leave the catheter in place for a long time.
  • the total leng t of the catheter is 52 cm. ;partial measurements of this total are the following ones: 5 " the portion from the funnel(included) to the base of the balloon is 35 cm. The funnel is 4,5 cm.
  • E) - 5 holes are positioned on the left side of the catheter. 9 - 5 holes are positioned on the right side of the catheter,in alternate fashion to the contralateral.
  • - 1 hole is positioned posteriorly and superiorly at the apex of the catheter and measures 10 mm.X 4 mm.
  • the balloon has a volume of 30 cc.,is made of the same material of the catheter and can be fused or sticked on it. (see point B) . 6)
  • the catheter has an external diameter(section) of 7,3 mm. ( equal to 22 French,a conventional measurement unit of the catheters) for the whole lenght of the catheter excluding the funnel portion.
  • the catheter has at its internal two co-axial channels: the first channel is 3,7 mm. in diameter(except for the funnel portion),is shaped as a tunnel,and put in communication the two extremities of the catheter: the holes along the tip of the catheter with the funnel portion and then the outside.
  • the second channel is positioned in the thickness of the wall of the catheter just peripheral and co-axial to the first channel and measures 0,7 mm. in diameter. This thin channel put in communication a continent valve, with the balloon.
  • the continent valve is implanted for fusion tangential to the catheter and placed parallel to the funnel,with the balloon.
  • the continent valve measures 6,5 cm.and generally for the 22 French catheters is about 1 cm. in the external diameter,depending from the type of valve already existing taken from the market. 7)
  • the first channel at the funnel end measures 7,5 mm. and can be connected to the common syringes for catheters of 60 ml. or 100 ml. funnel shaped in use to wash the bladder. 6 8 ) ⁇ he catheter material (see point 1 of the description) is mixed with Barium Solphate in such a percentage that can make the catheter visible inside the neo-bladder with a conventional X-Rays equipment in the post-operatory period.
  • the catheter of my invention even with large variations in
  • the novelty of the catheter I invented is in the particular design,shape and dimensions that are thought and conceived to be used to drain post-operatively the urinary neo- bladders reconstructed in children and adults with the use of the intestine or with the stomach.Differently,the catheter actually used at this purpose are the common bladder catheters neither specific nor affordables.

Abstract

A drainage catheter either for orthotopic urinary neo-bladders (anastomosis to the urethra), neo-bladders with stoma (anastomosis to the abdominal wall) or in enlargement entero-cistoplasties when the nautral urinary bladder is enlarged utilizing different intestinal segments is disclosed. The catheter is characterized by the wide draining surface for urine preventing dangerous inadvertent obstructions of the neo-bladders in the post-operatory period due to continuous formation of mucous cloths. This catheter also prevents and minimizes bleedings due to acid secretions.

Description

DRAINAGE CATHETER FOR URINARY NEO-BLADDERS
DESCRIPTION
TECHNICAL FIELD : SURGERY/UROLOGY
BACKGROUND ART
It is very common in the clinical practice the need to remove the urinary bladder in males,women,children,secondary to tumours,infections,neurologic abnormalities,or malformations.
Bladder trauma are also very frequent after a car crash,a working accident or other,and may require a cistectomy.
The reconstruction of a new urinary bladder is common in the urologic practice utilizing different segments of the intestine or of the stomach.
Two foundamental types of urinary neo-bladders allow the patient to achieve the urinary continence: the orthotopic neo-bladders where the patient voids through the penis, helping himself with the contraction of the abdominal musculature,and as in the normal condition the continence is achieved with the natural sfincter ; the neo-bladders with stoma in which the neo-bladder fashioned with a continence mechanism,is in communication with the abdominal wall,and the patient catheterizes himself through a stoma to void regularly.
The common post-operatory catheters utilized for the drainage of the neo-bladders are the same bladder catheters in use from many years to drain the natural bladder in several conditions(elderly condition,surgery of the
5 prostate,endoscopic or partial surgery of the bladder,etc...) .The construction of a a bladder(urethral) catheter is usually made with different materials ( Latex Rubber,Polivinile,Poliurethane,Co-Polimer,Silicone Rubber, etc..) in different shapes and dimensions, has a large
Q diffusion all over the world and do not shows particular, technical difficulties.The balloon that anchors the catheter is made of the same rubber-elastic material in different sizes and volumes,depending from the finalities,and can be inflated o deflated through a continent valve inserted
"7 tangential to the funnel of the catheter;the balloon can be fused to the catheter or simply sticked on it,depending on the technique.
The tip of a bladder catheter is very short, beeng about 3 cm. Q Using the intestine in reconstructing the bladder,the intestinal mucosa is responsible of the frequent obstructions of the catheter by producing mucous secretions and mucous clots,with the risk of dangerous passive overdistensions of the neo-bladder just recently Q accomplished.The nurse personnel and the doctors must frequently wash the neo-bladders through the catheter along the two weeks of post-operatory period.
This is more and more important thinking that is impossible to leave a continuous washing flow through the catheter in Q the post-operatory period,becouse a sudden and inadvertent obstructions not ::apidly recognized by the medical and nursing staff, could determine a dangerous overdistension of the new fashioned bladder with possible rupture. Moreover, when a portion of the stomach has been utilized
I *] in reconstructing the bladder,a particular surgical procedure suitable for chidren,there is a production of Chloridric acid,digestive enzymes and mucous from the mucosa of the portion of the stomach utilized in the reconstruction. 2 τhe medical therapy cannot stop adequately the secretion of Chloridric acid that is sometimes responsible of severe bleedings from the mucosa(gastric) of the neo- bladders, often complained for a few months after the neo-bladder procedure. 3 DISCLOSURE OF INVENTION
The use of a specific drainage catheter for neo- bladders that I invented,is indicated both for the orthotopic neo-bladders and the neo-bladders with stoma, either accomplished with the intestine or with the stomach.
Λ Λ Moreover,the specific catheter I invented for neo-bladders can be utilized to prevent the mucous obstruction when an enlargement cistoplasty of the natural bladder is performed with a segment of intestine. This is obtained by the particular lenght of the tip, 5 anci for a different positioning of the balloon from the apex of the catheter.
Moreover,the catheter is characterized by several holes along the tip of the catheter that allow a big surface of drainage;the catheter material warrants its
1 fo resistance to the mucous incrustation and to the acid secretions of the stomach.
Finally,for the specific design and the characteristics it is possible to wash and irrigate through the neo-bladder with extreme efficacy,removing the eventual mucous clots.
1 " The Bladder catheters commonly in use have the tip, very short -measured from the distal end of the balloon to the apex of the catheter. The catheter I invented,specially projected for urinary neo-bladders has a very long functioning tip, Q containing several holes to drain the urine and the mucous secretions produced by the mucosa of the intestine utilized in reconstructing the new bladder. The holes along the common bladder catheters are usually only three.The catheter I invented has several holes Q regularly placed along the two opposite sides of the tip in alternate fashion with the same diameter and distance one to each other side to side.
A bigger hole is positioned at the apex of the tip and it is the bigger one. 0 τhe specific,technical characteristic of the catheter I invented are the following ones:
1) The catheter can be made with the Latex Rubber Hydrogel coated or with Silicone Rubber materials,both fused and shaped. If the catheter is made in Latex Rubber it is necessary, in order to improve its resistance to the incrustations and to improve a constant lubrification of the urethra for all the time in which the catheter is in place, that the catheter will be Hydrogel coated,a technique that in 2 commonly in use on other catheters from the market. If the catheter is made in silicone rubber,the catheter maintain more consistance and rigidity without loosing too much the elasticity,and also the silicone make the catheter resistant to the incrustations from mucous and from the erosion by the acid secretions from the stomach when utilized,allowing to leave the catheter in place for a long time.
2) The following measurements are referred to a catheter of
22 French,the most commonly used in the clinical urologic « practice.
"French" is a common measurement unit for bladder catheters and follows this equation: 1 mm.= 0,39 inches = 3 French.
A) The total leng t of the catheter is 52 cm. ;partial measurements of this total are the following ones: 5 "the portion from the funnel(included) to the base of the balloon is 35 cm. The funnel is 4,5 cm.
B) From the base of the balloon to the distal end of the balloon the lenght is 3 cm if the balloon is fused to the catheter.Depending on the technical modality of (5 construction,the balloon can also be sticked to the catheter covering it for 3,5 cm. while the catheter maintains the same total lenght reported above of 52 cm. C) From the distal end of the balloon to the tip of the catheter the lenght is 14 cm. *7 3) ^e tip of the catheter is close at the apex,rounded acutely and 1 hole of 10 mm.X 4 mm. is placed posteriorly and superiorly to the apex.
4) The number of the holes placed along the surface of the tip (from the distal end of the balloon to the apex of the o catheter measuring 14 cm. is divided as follow:
D) A total of 11 holes, 10 out of them measure 8 mm.X 3 mm.; 1 hole measures 10 mm.X 4 mm.
E) - 5 holes are positioned on the left side of the catheter. 9 - 5 holes are positioned on the right side of the catheter,in alternate fashion to the contralateral.
- 1 hole is positioned posteriorly and superiorly at the apex of the catheter and measures 10 mm.X 4 mm.
F) The distance between the opposite holes, from side to 0 side of the catheter measures 1,6 cm.
5) The balloon has a volume of 30 cc.,is made of the same material of the catheter and can be fused or sticked on it. (see point B) . 6) The catheter has an external diameter(section) of 7,3 mm. ( equal to 22 French,a conventional measurement unit of the catheters) for the whole lenght of the catheter excluding the funnel portion. G) The catheter has at its internal two co-axial channels: the first channel is 3,7 mm. in diameter(except for the funnel portion),is shaped as a tunnel,and put in communication the two extremities of the catheter: the holes along the tip of the catheter with the funnel portion and then the outside.
The second channel is positioned in the thickness of the wall of the catheter just peripheral and co-axial to the first channel and measures 0,7 mm. in diameter. This thin channel put in communication a continent valve, with the balloon.
The continent valve is implanted for fusion tangential to the catheter and placed parallel to the funnel,with the balloon.
The continent valve measures 6,5 cm.and generally for the 22 French catheters is about 1 cm. in the external diameter,depending from the type of valve already existing taken from the market. 7) The first channel at the funnel end measures 7,5 mm. and can be connected to the common syringes for catheters of 60 ml. or 100 ml. funnel shaped in use to wash the bladder. 6 8) τhe catheter material (see point 1 of the description) is mixed with Barium Solphate in such a percentage that can make the catheter visible inside the neo-bladder with a conventional X-Rays equipment in the post-operatory period. The catheter of my invention,even with large variations in
^ sizes from the child to the adult (10 Fr.;12 Fr.;l4 Fr.;16 Fr.;18 Fr. ;20.Fr. ;22 Fr.;24 Fr. where "Fr." means "French" a common measurement unit of the catheters) , can maintain the same configuration and the same shape following this equation 1 mm.= 0,39 inches = 3 French.
38 So,a new generation of post-operative catheters develops in different sizes for the adequate drainage of continent neo- bladders either orthotopic or with stoma.
BRIEF DESCRIPTION OF THE DRAWINGS
One drawing is presented,in three copies.The drawing show
39 the total design of the catheter,and point out the tip of the catheter with the several holes along its two sides,and the hole at the apex of the catheter,with the apex closed an rounded acutely. Moreover,the drawing point out the ballooon inflated, the funnel end of catheter and the valve fused tangential and parallel to it.
MODES FOR CARRYING OUT THE INVENTION
The technology in producing bladder catheters,is well established all over the world by many years,and the catheter I invented can be made with the existing materials and technologies.
The novelty of the catheter I invented is in the particular design,shape and dimensions that are thought and conceived to be used to drain post-operatively the urinary neo- bladders reconstructed in children and adults with the use of the intestine or with the stomach.Differently,the catheter actually used at this purpose are the common bladder catheters neither specific nor affordables.

Claims

CLAIMS OF INVENTION 1) Drainage catheter for continent urinary neo-bladders accomplished with the intestine or with the stomach,
22 French in size( a common measurement unit of the catheters) ,made in Latex Rubber,Hydrogel coated, or made in Silicone Rubber, both materials fused and shaped.This allows the post-operatory drainage of mucous secretions and mucous clots from the intestine,and acid secretions from the stomach,when these organs are utilized for the urinary neo-bladder reconstruction.
2) Drainage catheter for continent urinary neo-bladders as the first claim of invention,characterized by tip of 14 cm. ( measured from the distal end of the balloon, to the apex of the catheter,out of 52 cm. of total lenght of the catheter.The very long tip of the catheter,is able to drain extremely well the mucous or acid secretions when the intestine or the stomach are utilized to reconstruct the urinary neo-bladder.
3) Drainage catheter for continent urinary neo-bladders as the above claims of invention,characterized by the presence of 11 holes placed along the surface of the functional tip of the catheter,10 holes out of 11 holes measure 8 mm. X 3mm.each one,and are placed in alternate fashion on each lateral surface of the tip,l hole out of 11 holes measures 10 mm. X 4 mm. , and is placed just posteriorly and anteriorly to the apex of the tip,that is ft closed and rounded acutely.
4) Drainage catheter for continent urinary neobladders as the above claims of invention,characterized by mixing Barium Solphate in such a percentage to the material of the catheter to make the catheter visible with a conventional X- Ray equipment in the post-operatory period.
5) Drainage catheter for continent urinary neo-bladders as the above claims of invention,characterized by a 30 cc. balloon made with the same material of the catheter,that can be fused or sticked on it. 0 6) Drainage catheter for continent urinary neo-bladders as the above claims of invention,characterized by a continent valve that allows to maintain the balloon inflated,to anchor the catheter to the body of the patient. 7) Drainage catheter for continent urinary neo-bladders as *] the above claims of invention,that can widely change in measure from the child to the adult as follow :10 Fr.; 12 Fr.;14 Fr.;16 Fr.;18 Fr.; 20 Fr.;22 Fr. ; 24 Fr. ; maintaining the same configuration and the same shape,where "Fr." means "French" a common measurement unit of the catheters.
PCT/IT1995/000143 1994-09-02 1995-08-31 Drainage catheter for urinary neo-bladders WO1996007447A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP95930000A EP0751798A1 (en) 1994-09-02 1995-08-31 Drainage catheter for urinary neo-bladders
AU33754/95A AU3375495A (en) 1994-09-02 1995-08-31 Drainage catheter for urinary neo-bladders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM94A000561 1994-09-02
ITRM940561A IT1272800B (en) 1994-09-02 1994-09-02 DRAINAGE CATHETER FOR CONTINENT URINARY NEO-BLADDS MADE WITH THE USE OF THE INTESTINE OR STOMACH

Publications (1)

Publication Number Publication Date
WO1996007447A1 true WO1996007447A1 (en) 1996-03-14

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Application Number Title Priority Date Filing Date
PCT/IT1995/000143 WO1996007447A1 (en) 1994-09-02 1995-08-31 Drainage catheter for urinary neo-bladders

Country Status (4)

Country Link
EP (1) EP0751798A1 (en)
AU (1) AU3375495A (en)
IT (1) IT1272800B (en)
WO (1) WO1996007447A1 (en)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7717928B2 (en) 2005-05-20 2010-05-18 Ams Research Corporation Anastomosis device configurations and methods
US7771443B2 (en) 2005-05-20 2010-08-10 Ams Research Corporation Anastomosis device approximating structure configurations
US7850649B2 (en) 2007-11-09 2010-12-14 Ams Research Corporation Mechanical volume control for injection devices
US7993264B2 (en) 2006-11-09 2011-08-09 Ams Research Corporation Orientation adapter for injection tube in flexible endoscope
US8066725B2 (en) 2006-10-17 2011-11-29 Ams Research Corporation Anastomosis device having improved safety features
US8277466B2 (en) 2006-11-14 2012-10-02 Ams Research Corporation Anastomosis device and method
US8388349B2 (en) 2009-01-14 2013-03-05 Ams Research Corporation Anastomosis deployment force training tool
US8491525B2 (en) 2006-11-17 2013-07-23 Ams Research Corporation Systems, apparatus and associated methods for needleless delivery of therapeutic fluids
US8529590B2 (en) 2002-08-22 2013-09-10 Ams Research Corporation Anastomosis device and related methods
US8636756B2 (en) 2005-02-18 2014-01-28 Ams Research Corporation Anastomosis device and surgical tool actuation mechanism configurations
US8747386B2 (en) 2010-12-16 2014-06-10 Ams Research Corporation Anastomosis device and related methods
US8764775B2 (en) 2002-08-22 2014-07-01 Ams Research Corporation Anastomosis device and related methods
US9307991B2 (en) 2002-08-22 2016-04-12 Ams Research, Llc Anastomosis device and related methods
US9381335B2 (en) 2012-03-21 2016-07-05 Ams Research Corporation Bladder wall drug delivery system
US10857324B2 (en) 2014-08-26 2020-12-08 C. R. Bard, Inc. Urinary catheter

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US4211233A (en) * 1978-01-05 1980-07-08 Lin Edward D Urethral catheter
GB2123300A (en) * 1982-07-14 1984-02-01 Urotek Inc Urodynamic catheter
EP0381042A1 (en) * 1989-02-02 1990-08-08 Willy Rüsch Ag Catheter
EP0471429A2 (en) * 1990-02-26 1992-02-19 Cook Incorporated Drainage catheter
EP0483941A2 (en) * 1990-11-01 1992-05-06 C.R. Bard, Inc. Lubricious hydrogel coatings

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US3993080A (en) * 1974-03-01 1976-11-23 Loseff Herbert S Suction tube and retrograde flushing for wounds, body cavities and the like
US4211233A (en) * 1978-01-05 1980-07-08 Lin Edward D Urethral catheter
GB2123300A (en) * 1982-07-14 1984-02-01 Urotek Inc Urodynamic catheter
EP0381042A1 (en) * 1989-02-02 1990-08-08 Willy Rüsch Ag Catheter
EP0471429A2 (en) * 1990-02-26 1992-02-19 Cook Incorporated Drainage catheter
EP0483941A2 (en) * 1990-11-01 1992-05-06 C.R. Bard, Inc. Lubricious hydrogel coatings

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Title
V.LENT: "Einroll-Ballon-Silikonkatheter zur Suprapubischen Harnblasendrainage", UROLOGE (B), vol. 26, SPRINGER-VERLAG, pages 186 - 188 *

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8764775B2 (en) 2002-08-22 2014-07-01 Ams Research Corporation Anastomosis device and related methods
US8551126B2 (en) 2002-08-22 2013-10-08 Ams Research Corporation Anastomosis device and related methods
US8529590B2 (en) 2002-08-22 2013-09-10 Ams Research Corporation Anastomosis device and related methods
US9307991B2 (en) 2002-08-22 2016-04-12 Ams Research, Llc Anastomosis device and related methods
US8636756B2 (en) 2005-02-18 2014-01-28 Ams Research Corporation Anastomosis device and surgical tool actuation mechanism configurations
US8425540B2 (en) 2005-05-20 2013-04-23 Ams Research Corporation Anastomosis device approximating structure configurations
US8277467B2 (en) 2005-05-20 2012-10-02 Ams Research Corporation Anastomosis device configurations and methods
US7771443B2 (en) 2005-05-20 2010-08-10 Ams Research Corporation Anastomosis device approximating structure configurations
US7717928B2 (en) 2005-05-20 2010-05-18 Ams Research Corporation Anastomosis device configurations and methods
US8066725B2 (en) 2006-10-17 2011-11-29 Ams Research Corporation Anastomosis device having improved safety features
US7993264B2 (en) 2006-11-09 2011-08-09 Ams Research Corporation Orientation adapter for injection tube in flexible endoscope
US8277466B2 (en) 2006-11-14 2012-10-02 Ams Research Corporation Anastomosis device and method
US8663257B2 (en) 2006-11-14 2014-03-04 Ams Research Corporation Anastomosis device and method
US8491525B2 (en) 2006-11-17 2013-07-23 Ams Research Corporation Systems, apparatus and associated methods for needleless delivery of therapeutic fluids
US7850649B2 (en) 2007-11-09 2010-12-14 Ams Research Corporation Mechanical volume control for injection devices
US9706900B2 (en) 2007-11-19 2017-07-18 Ams Research Corporation Systems, apparatus and associated methods for needleless delivery of therapeutic fluids
US8388349B2 (en) 2009-01-14 2013-03-05 Ams Research Corporation Anastomosis deployment force training tool
US8747386B2 (en) 2010-12-16 2014-06-10 Ams Research Corporation Anastomosis device and related methods
US9381335B2 (en) 2012-03-21 2016-07-05 Ams Research Corporation Bladder wall drug delivery system
US11850370B2 (en) 2014-08-26 2023-12-26 C. R. Bard, Inc. Urinary catheter
US10857324B2 (en) 2014-08-26 2020-12-08 C. R. Bard, Inc. Urinary catheter
US10874825B2 (en) 2014-08-26 2020-12-29 C. R. Bard, Inc. Urinary catheter

Also Published As

Publication number Publication date
EP0751798A1 (en) 1997-01-08
ITRM940561A1 (en) 1996-03-02
IT1272800B (en) 1997-06-30
AU3375495A (en) 1996-03-27
ITRM940561A0 (en) 1994-09-02

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