WO1995027041A1 - Additifs pour des milieux de culture destines a des bioreacteurs - Google Patents

Additifs pour des milieux de culture destines a des bioreacteurs Download PDF

Info

Publication number
WO1995027041A1
WO1995027041A1 PCT/US1994/008295 US9408295W WO9527041A1 WO 1995027041 A1 WO1995027041 A1 WO 1995027041A1 US 9408295 W US9408295 W US 9408295W WO 9527041 A1 WO9527041 A1 WO 9527041A1
Authority
WO
WIPO (PCT)
Prior art keywords
bioreactors
culture media
media additives
hollow fiber
culture medium
Prior art date
Application number
PCT/US1994/008295
Other languages
English (en)
Inventor
Randal A. Goffe
Original Assignee
Unisyn Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unisyn Technologies, Inc. filed Critical Unisyn Technologies, Inc.
Priority to EP94922694A priority Critical patent/EP0711339A1/fr
Priority to AU73713/94A priority patent/AU7371394A/en
Priority to JP7525645A priority patent/JPH08511173A/ja
Publication of WO1995027041A1 publication Critical patent/WO1995027041A1/fr
Priority to NO954854A priority patent/NO954854L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

On décrit un milieu de culture destiné à des bioréacteurs à fibres creuses, qui contient de l'hémoglobine stabilisée ou une émulsion d'un composé perfluoré. Le milieu de culture favorise l'absorption et l'utilisation de l'oxygène. L'efficacité du bioréacteur est améliorée. On obtient ainsi de nouvelles configurations de systèmes, de nouveaux équipements et de nouveaux procédés de culture de cellules faisant appel à des fibres creuses et à des réacteurs agités.
PCT/US1994/008295 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs WO1995027041A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP94922694A EP0711339A1 (fr) 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs
AU73713/94A AU7371394A (en) 1994-04-01 1994-07-26 Culture media additives for bioreactors
JP7525645A JPH08511173A (ja) 1994-04-01 1994-07-26 バイオリアクターのための培養培地添加物
NO954854A NO954854L (no) 1994-04-01 1995-11-29 Kulturmedietilsetningsstoffer for bioreaktorer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
USPCT/US94/03613 1994-04-01
PCT/US1994/003613 WO1995027040A1 (fr) 1994-04-01 1994-04-01 Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses

Publications (1)

Publication Number Publication Date
WO1995027041A1 true WO1995027041A1 (fr) 1995-10-12

Family

ID=22242416

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1994/003613 WO1995027040A1 (fr) 1994-04-01 1994-04-01 Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses
PCT/US1994/008295 WO1995027041A1 (fr) 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US1994/003613 WO1995027040A1 (fr) 1994-04-01 1994-04-01 Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses

Country Status (6)

Country Link
EP (1) EP0711339A1 (fr)
JP (1) JPH08511173A (fr)
AU (2) AU6766994A (fr)
CA (1) CA2163618A1 (fr)
NO (1) NO954854L (fr)
WO (2) WO1995027040A1 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001023520A1 (fr) * 1999-09-30 2001-04-05 Unisearch Limited Technique et appareil permettant de cultiver des cellules
WO2002022775A1 (fr) * 2000-09-13 2002-03-21 Csir Dispositif bioreacteur
AU781265B2 (en) * 1999-09-30 2005-05-12 Unisearch Limited Method and apparatus for culturing cells
WO2010122080A1 (fr) * 2009-04-23 2010-10-28 Hemarina Bioréacteur utilisant des molécules transporteuses d'oxygène
US20120052136A1 (en) * 2009-05-07 2012-03-01 Hemarina Novel heamoglobin and uses thereof
US9677042B2 (en) 2010-10-08 2017-06-13 Terumo Bct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
US11667881B2 (en) 2014-09-26 2023-06-06 Terumo Bct, Inc. Scheduled feed
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255109B1 (en) * 1998-06-24 2001-07-03 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Nitric oxide-scavenging system for culturing oocytes, embryos, or other cells
GB9915413D0 (en) * 1999-07-01 1999-09-01 Glaxo Group Ltd Propagation method
DE10136912A1 (de) * 2001-07-30 2003-02-20 Wolfgang Fege Verfahren zur Sauerstoffversorgung von Mikroorganismenkulturen, Kulturen von tierischen oder menschlichen Körperzellen und von Gewebekulturen, Organoiden, Organen
BRPI0711901A2 (pt) 2006-05-22 2012-03-06 The Regents Of The University Of California Composições e métodos para a liberação de oxigênio

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997396A (en) * 1973-07-02 1976-12-14 Monsanto Company Method for the in vitro propagation and maintenance of cells
US5223428A (en) * 1982-12-14 1993-06-29 Baxter International Inc. Method for in vitro culture of mammalian cells
US5264555A (en) * 1992-07-14 1993-11-23 Enzon, Inc. Process for hemoglobin extraction and purification

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180676A (en) * 1984-06-14 1993-01-19 Teijin Limited Method of cultivating animal or plant cells
EP0260627B1 (fr) * 1986-09-19 1993-06-16 Shimadzu Corporation Incubateur sous pression
DE3871206D1 (de) * 1987-03-24 1992-06-25 Grace W R & Co Basisnaehrmedium fuer eine zellkultur.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997396A (en) * 1973-07-02 1976-12-14 Monsanto Company Method for the in vitro propagation and maintenance of cells
US5223428A (en) * 1982-12-14 1993-06-29 Baxter International Inc. Method for in vitro culture of mammalian cells
US5264555A (en) * 1992-07-14 1993-11-23 Enzon, Inc. Process for hemoglobin extraction and purification

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001023520A1 (fr) * 1999-09-30 2001-04-05 Unisearch Limited Technique et appareil permettant de cultiver des cellules
AU781265B2 (en) * 1999-09-30 2005-05-12 Unisearch Limited Method and apparatus for culturing cells
WO2002022775A1 (fr) * 2000-09-13 2002-03-21 Csir Dispositif bioreacteur
FR2814468A1 (fr) * 2000-09-13 2002-03-29 Csir Dispositif servant de bioreacteur
NL1018942C2 (nl) * 2000-09-13 2002-07-02 Csir Bioreactor.
US7129082B2 (en) 2000-09-13 2006-10-31 Csir Bio-reactor device
US10119110B2 (en) 2009-04-23 2018-11-06 Hemarina Bioreactor using oxygen-carrying molecules
WO2010122080A1 (fr) * 2009-04-23 2010-10-28 Hemarina Bioréacteur utilisant des molécules transporteuses d'oxygène
US11224218B2 (en) * 2009-05-07 2022-01-18 Hemarina Heamoglobin and uses thereof
US20120052136A1 (en) * 2009-05-07 2012-03-01 Hemarina Novel heamoglobin and uses thereof
US11746319B2 (en) 2010-10-08 2023-09-05 Terumo Bct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US9677042B2 (en) 2010-10-08 2017-06-13 Terumo Bct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US10669519B2 (en) 2010-10-08 2020-06-02 Terumo Bct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US10870827B2 (en) 2010-10-08 2020-12-22 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US11613727B2 (en) 2010-10-08 2023-03-28 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US9725689B2 (en) 2010-10-08 2017-08-08 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US11773363B2 (en) 2010-10-08 2023-10-03 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US11667881B2 (en) 2014-09-26 2023-06-06 Terumo Bct, Inc. Scheduled feed
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion

Also Published As

Publication number Publication date
AU7371394A (en) 1995-10-23
NO954854D0 (no) 1995-11-29
AU6766994A (en) 1995-10-23
NO954854L (no) 1995-11-29
EP0711339A1 (fr) 1996-05-15
WO1995027040A1 (fr) 1995-10-12
CA2163618A1 (fr) 1995-10-12
JPH08511173A (ja) 1996-11-26

Similar Documents

Publication Publication Date Title
WO1995027041A1 (fr) Additifs pour des milieux de culture destines a des bioreacteurs
AU2528797A (en) Cell culture media for mammalian cells
EP0599651A3 (fr) Bioréacteur pour la culture de cellules en perfusion.
AU2154200A (en) Low oxygen culturing of central nervous system progenitor cells
DE69638059D1 (de) Kulturmedium für mikroorganismen
AU2387795A (en) Culture medium for maintaining viability of mammalian cells
AU4330597A (en) Serum-free mammalian cell culture medium, and uses thereof
EP0725134A3 (fr) Bioréacteur flexible pour cellules thérapeutiques
EP0590341A3 (fr) Module pour la culture et l'utilisation du rendement métabolique ou l'obtention de micro-organismes.
PT964831E (pt) Metodo para obter crescimento de formato granular de um microorganismo num reactor
AU3143097A (en) Enhanced production of taxanes by cell cultures of Taxus species
DE59709633D1 (de) Verfahren zur herstellung von polyglycol(meth)acrylaten
AU2001281859A1 (en) Immobilising carrier comprising a porous medium
EP0289908A3 (fr) Micro-organismes et méthodes pour dégrader les parois des cellules de plantes et les hydrocarbures complexes
ATE289349T1 (de) Vorläufer von normalen neuralen epithelzellen
IL113497A0 (en) Method for controlling metallophosphate precipitation in high cell density fermentations
AU4131397A (en) Apparatus for cultivating microorganisms
WO1996007730A3 (fr) Procede chimique favorisant la proliferation de cellules animales
AU2182801A (en) Method for producing adherent animal cells
AU631651B2 (en) Method for culturing cells
DE9411876U1 (de) Kulturgefäß für Zellkulturen
DE3782333D1 (de) Verfahren und anlage zur herstellung von biogas aus dickfluessigen vergaerbaren medien.
Powell ANTIBODY RESPONSIVENESS IN BABOONS (PAPIO CYNOCEPHALUS) DURING CHRONIC SCHISTOSOMIASIS MANSONI.
Fedotov Apparatus for microorganism cultivation with recycled air supply.
RO99452B1 (ro) Procedeu pentru obtinerea biomasei bacteriene

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 1994922694

Country of ref document: EP

AK Designated states

Kind code of ref document: A1

Designated state(s): AU CA CN JP KR NO NZ US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

ENP Entry into the national phase

Ref document number: 1995 553296

Country of ref document: US

Date of ref document: 19951122

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2163618

Country of ref document: CA

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWP Wipo information: published in national office

Ref document number: 1994922694

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1994922694

Country of ref document: EP