WO1995021922A3 - Reactifs pour l'hepatite non-a, non-b, non-c, non-d et procede pour leur utilisation - Google Patents

Reactifs pour l'hepatite non-a, non-b, non-c, non-d et procede pour leur utilisation Download PDF

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Publication number
WO1995021922A3
WO1995021922A3 PCT/US1995/002118 US9502118W WO9521922A3 WO 1995021922 A3 WO1995021922 A3 WO 1995021922A3 US 9502118 W US9502118 W US 9502118W WO 9521922 A3 WO9521922 A3 WO 9521922A3
Authority
WO
WIPO (PCT)
Prior art keywords
hgbv
hepatitis
methods
amino acid
nucleic acid
Prior art date
Application number
PCT/US1995/002118
Other languages
English (en)
Other versions
WO1995021922A2 (fr
Inventor
John N Simons
Tami J Pilot-Matias
George J Dawson
George G Schlauder
Suresh M Desai
Thomas P Leary
Anthony Scott Muerhoff
James Carl Erker
Sheri L Buijk
Isa K Mushahwar
Original Assignee
Abbott Lab
John N Simons
Pilot Matias Tami J
George J Dawson
George G Schlauder
Suresh M Desai
Thomas P Leary
Anthony Scott Muerhoff
James Carl Erker
Sheri L Buijk
Isa K Mushahwar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab, John N Simons, Pilot Matias Tami J, George J Dawson, George G Schlauder, Suresh M Desai, Thomas P Leary, Anthony Scott Muerhoff, James Carl Erker, Sheri L Buijk, Isa K Mushahwar filed Critical Abbott Lab
Priority to DE69533792T priority Critical patent/DE69533792D1/de
Priority to EP95911823A priority patent/EP0745129B1/fr
Priority to JP52144195A priority patent/JP3580822B2/ja
Priority to AT95911823T priority patent/ATE283360T1/de
Priority to US08/424,550 priority patent/US6720166B2/en
Priority to US08/417,629 priority patent/US5981172A/en
Publication of WO1995021922A2 publication Critical patent/WO1995021922A2/fr
Priority to PCT/US1997/023767 priority patent/WO1998029747A1/fr
Publication of WO1995021922A3 publication Critical patent/WO1995021922A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Séquences d'acide nucléique et d'acides aminés du virus de l'hépatite GB (VHGB) utiles pour diverses applications dans le diagnostic et le traitement, kits pour la mise en oeuvre des séquences d'acides nucléiques et d'acides aminés du VHGB, particules immunogènes du VHGB et anticorps se liant spécifiquement au VHGB. L'invention décrit également des procédés pour la production d'anticorps polyclonaux ou monoclonaux à partir des séquences d'acides nucléiques ou d'acides aminés du VHGB.
PCT/US1995/002118 1994-02-14 1995-02-14 Reactifs pour l'hepatite non-a, non-b, non-c, non-d et procede pour leur utilisation WO1995021922A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE69533792T DE69533792D1 (de) 1994-02-14 1995-02-14 Reagentien für non-a, non-b, non-c, non-d, non-e hepatitis und methoden für ihre nutzung
EP95911823A EP0745129B1 (fr) 1994-02-14 1995-02-14 Reactifs pour l'hepatite non-a, non-b, non-c, non-d et procede pour leur utilisation
JP52144195A JP3580822B2 (ja) 1994-02-14 1995-02-14 非ａ非ｂ非ｃ非ｄ非ｅ型肝炎試薬及びそれらの使用方法
AT95911823T ATE283360T1 (de) 1994-02-14 1995-02-14 Reagentien für non-a, non-b, non-c, non-d, non-e hepatitis und methoden für ihre nutzung
US08/424,550 US6720166B2 (en) 1994-02-14 1995-02-14 Non-a, non-b, non-c, non-c, non-d, non-e hepatitis reagents and methods for their use
US08/417,629 US5981172A (en) 1994-02-14 1995-04-06 Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use
PCT/US1997/023767 WO1998029747A1 (fr) 1994-11-23 1997-12-23 Reactifs et procedes permettant de detecter un antigene du virus de l'hepatite gb

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US19603094A 1994-02-14 1994-02-14
US24265494A 1994-05-13 1994-05-13
US28331494A 1994-07-29 1994-07-29
US08/196,030 1994-07-29
US08/283,314 1994-07-29
US08/242,654 1994-07-29
US34418594A 1994-11-23 1994-11-23
US34419094A 1994-11-23 1994-11-23
US08/344,190 1994-11-23
US08/344,185 1994-11-23
US34455795A 1995-01-27 1995-01-27
US08/344,557 1995-01-27

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US37755795A Continuation-In-Part 1994-02-14 1995-01-30

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US08/417,629 Continuation-In-Part US5981172A (en) 1994-02-14 1995-04-06 Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use
US08/467,344 Division US6586568B1 (en) 1994-02-14 1995-06-06 Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US08/488,446 Division US6558898B1 (en) 1994-02-14 1995-06-07 Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use

Publications (2)

Publication Number Publication Date
WO1995021922A2 WO1995021922A2 (fr) 1995-08-17
WO1995021922A3 true WO1995021922A3 (fr) 2001-09-13

Family

ID=27558868

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/002118 WO1995021922A2 (fr) 1994-02-14 1995-02-14 Reactifs pour l'hepatite non-a, non-b, non-c, non-d et procede pour leur utilisation

Country Status (2)

Country Link
CA (1) CA2166313A1 (fr)
WO (1) WO1995021922A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5859230A (en) * 1992-07-30 1999-01-12 Genelabs Technologies, Inc. Non-A/non-B/non-C/non-D/non-E hepatitis agents and molecular cloning thereof
US5981172A (en) * 1994-02-14 1999-11-09 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use
US6156495A (en) * 1994-02-14 2000-12-05 Abbott Laboratories Hepatitis GB virus recombinant proteins and uses thereof
AU2549195A (en) * 1994-05-20 1995-12-18 Genelabs Technologies, Inc. Non-A/non-B/non-C/non-D/non-E hepatitis agents and molecular cloning thereof
US5874563A (en) * 1994-05-20 1999-02-23 Genelabs Technologies, Inc. Hepatitis G virus and molecular cloning thereof
MX9605666A (es) * 1994-05-20 1998-05-31 Genelabs Tech Inc Virus de hepatitis g y clonacion molecular del mismo.
US5824507A (en) * 1994-05-20 1998-10-20 Genelabs Technologies, Inc. Hepatitis G virus and molecular cloning thereof
WO1998029747A1 (fr) * 1994-11-23 1998-07-09 Abbott Laboratories Reactifs et procedes permettant de detecter un antigene du virus de l'hepatite gb
US5709997A (en) * 1995-08-14 1998-01-20 Abbott Laboratories Nucleic acid detection of hepatitis GB virus
US5807670A (en) * 1995-08-14 1998-09-15 Abbott Laboratories Detection of hepatitis GB virus genotypes
IT1283893B1 (it) * 1996-01-24 1998-05-07 Sorin Biomedica Diagnostics Sp Metodo per rilevare sequenze nucleotidiche di virus associati a epatiti nona-none, peptidi e composizioni
DE19613406A1 (de) * 1996-04-03 1997-10-09 Boehringer Mannheim Gmbh Expression von HGV-Antigenen und deren Verwendung
CA2257851C (fr) * 1996-05-24 2011-11-15 Biogen, Inc. Modulateurs de la regeneration tissulaire
WO1999058561A1 (fr) * 1998-05-14 1999-11-18 Pasteur Merieux Serums & Vaccins Mimotopes du virus de l'hepatite c
US6541616B1 (en) 1998-10-01 2003-04-01 Antex Biologics Inc. Moraxella catarrhalis protein, gene sequence and uses thereof
GB9912432D0 (en) * 1999-05-27 1999-07-28 Angeletti P Ist Richerche Bio Novel gbv sequence
US7129342B1 (en) 1999-06-04 2006-10-31 The United States Of America As Represented By The Department Of Health And Human Services Infectious cDNA clone of GB virus B and uses thereof
ATE408013T1 (de) * 1999-06-04 2008-09-15 Us Gov Health & Human Serv Infektiöses cdna klon des gb-virus b und dessen verwendungen

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA, vol. 41, no. 1, pages 83 - 89 *
BIOLOGICAL ABSTRACTS, vol. 94, Philadelphia, PA, US; abstract no. 407262, M. TAKACS ET AL.: "Detection of transfusion-transmitted hepatitis caused by non-A non-b, non-c hepatitis" *
P. KARAYIANNIS ET AL.: "Studies of GB agent in tamarins", HEPATOLOGY, vol. 9, no. 2, pages 186 - 192 *
V. TIERS ET AL.: "Post-transfusional anti-HCV-negative non-A non-B hepatitis (II) serological and polymerase chain reaction analysis for hepatitis C and hepatitis B viruses", J. HEPATOL., vol. 18, no. 1, pages 34 - 39 *

Also Published As

Publication number Publication date
WO1995021922A2 (fr) 1995-08-17
CA2166313A1 (fr) 1995-08-17

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