WO1995003771A1 - Traitement de troubles buccaux - Google Patents

Traitement de troubles buccaux Download PDF

Info

Publication number
WO1995003771A1
WO1995003771A1 PCT/AU1994/000426 AU9400426W WO9503771A1 WO 1995003771 A1 WO1995003771 A1 WO 1995003771A1 AU 9400426 W AU9400426 W AU 9400426W WO 9503771 A1 WO9503771 A1 WO 9503771A1
Authority
WO
WIPO (PCT)
Prior art keywords
support
guard
composition
mouth
solid composition
Prior art date
Application number
PCT/AU1994/000426
Other languages
English (en)
Inventor
Suzanne Jane Campbell
Original Assignee
Pacific Rim Productions Pty. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pacific Rim Productions Pty. Ltd. filed Critical Pacific Rim Productions Pty. Ltd.
Priority to AU73408/94A priority Critical patent/AU7340894A/en
Publication of WO1995003771A1 publication Critical patent/WO1995003771A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/003—Sticks, e.g. lollipops with drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Definitions

  • Such liquid preparations are not site specific and therefore can and usually do have negative side effects such as drowsiness, nausea, stomach and intestinal irritations and the like.
  • Liquid preparations are used because children, and especially young children, are generally not permitted to utilise treatments designed to dissolve slowly in the mouth. Therefore, treatments such as lozenges and various types of slow release tablets are not permitted. This is because young children can choke on the lozenge or tablet if too small and if the lozenge tablet is too large, the child is unable to effectively chew or suck the product.
  • a further consideration is that children have a tendency to break up a lozenge or like member and to swallow the smaller pieces. As well as the possibility of choking, such an action also negates the required resident time of the lozenge in the mouth and throat area.
  • the present invention has been devised to develop a simple yet very effective technique to treat oral ailments by improving the residence time of the medicated portion in the mouth and throat region, especially for a child.
  • a shaped solid composition comprising one or more active components to treat oral ailments, and one or more non- toxic components which can slowly dissolve upon sucking or licking the component, and providing a support for supporting the solid composition, whereby a child may hold the support and lick or suck the solid composition to slowly introduce the active components into the mouth or throat region.
  • the solid composition may be of any desired shape or configuration and can be shaped to provide appeal to children.
  • the shaped composition may be in the form of a teddybear, dinosaur, jungle animal, cartoon characters or simply plain spheres, triangles and the like.
  • the number and type of active ingredient may vary to suit various ailments. For instance, for sore throats, the active ingredient may be similar to those found in commercially available lozenges. For sore gums and teeth, a pain-reducing or killing active ingredient or ingredients may be used alone or in association with other ingredients. In further alternatives, antiseptic or antibacterial components may be used. The amount of the active components can be varied to suit the type of ailment, and the size or body weight of the person taking the treatment.
  • the non-toxic component may vary depending on a variety of factors. These may include the desired rate of dissolving of the component. For instance, the non- toxic component may be selected depending on its release rate of the active components. Furthermore, the non- toxic component may be selected from types which will be difficult to break into smaller pieces by children thereby minimising the possibility of the solid composition being broken into pieces instead of licked or sucked. Various flavours and colours may be added to improve the appeal of the solid composition if desired.
  • the active components may be mixed with the non-toxic component, either randomly or organised into discreet areas or zones.
  • a solid composition may include layers or zones of the same or different active components which will then be released into the person's mouth at different times.
  • the support suitably comprises a stick, rod, shaft or like member and is suitably of a length to allow it to be adequately gripped by a child's hand and also of a length to prevent the support from being inserted entirely into a child's mouth.
  • the end of the support containing the components may have a novelty shape as an inducement for children to finish sucking or licking the component.
  • the surface of the support in the region of the solid composition may be ribbed to provide a greater surface area for attachment of the solid composition.
  • the ribbing can be at 90° to the support or angled towards the gripping portion of the support to further aid retention of the solid composition.
  • the ribs are of a larger diameter in the middle of the ribbing than at the extremities of the ribbing.
  • the support may also include a guard to prevent entry of the entire support into the child's mouth.
  • the guard can be an integral part of the support or a separate article attachable thereto. Typically, the guard is screwed onto the support using a long pitched thread for safety reasons.
  • a smaller guard can be screwed in place behind the larger guard to ensure that the former remains in place.
  • the support may be attached to the guard by fitting one or more resiliently deformable members on the support into apertures in the guard for receiving the members.
  • the guard will also have associated with it a handle.
  • the support can also be detached from the guard allowing the latter to be reused with a fresh solid composition-bearing support.
  • the solid composition may be protected by a wrapper or like member.
  • a solid composition is manufactured using as active components cetylpyridinium chloride and benzocaine in a non-toxic component which can slowly dissolve such as boiled candy, and the like.
  • active components cetylpyridinium chloride and benzocaine in a non-toxic component which can slowly dissolve such as boiled candy, and the like.
  • the amount of active components will be reduced for very young children and therefore it is envisaged that different types of solid compositions will be available for children of different age groups.
  • composition may be attached to a support in the form of a stick while still soft (for instance, upon heating) and when cooled, a glossy grease-proof paper covering can be wrapped around the solid composition.
  • Figures 1 and 2 depict ribbed portions of a support for the composition
  • FIGS 3 to 6 depict alternative supports having guards fitted thereto.
  • Figure 7 depicts a support and guard where the support is detachable for attachment of a fresh support.
  • BEST MODE Referring now to Figures 1 to 5, there are shown various forms of the support (1), or a portion thereof (la).
  • FIG 1 there is shown the ribbed portion of a support wherein the ribs (3) extend from the support at 90° to the centre line of the support.
  • An alternative form of ribbing is shown in Figures 2 to 7 where the ribs (4) are angled towards the gripping portion of the support.
  • the ribs provide a greater surface area for attachment of the solid support.
  • Figures 3 to 6 there is shown a guard (5) fitted to support (1).
  • the guard (5) is screwed onto support (1) via thread (6) in the embodiment shown in Figures 2 to 4.
  • the guard is an integral part of the support.
  • a smaller guard (5a) which acts as a locking device for guard (5), may be screwed onto the support (1).
  • the smaller guard is shown on the support in Figure 3.
  • the gripping portion (7) of the support may take different forms.
  • the gripping portion may be straight ( Figure 3), "J” shaped ( Figure 4), a hook ( Figure 5) or a ring ( Figure 6).
  • FIG. 7 A further embodiment of the invention is shown in Figure 7 where the ribbed support (11) is attachable to, and detachable from, the guard (12).
  • the support is ribbed (13) in the region of attachment of the solid composition (14) shown in phantom.
  • the support (11) is fixed to the guard via resilient members (11a) which locate in apertures (15) in the guard (12).
  • the support (11) is detached from guard (12) by forcing members (11a) together so that they may be removed from apertures (15).
  • a handle (16) is associated with the guard (12) for gripping the support/guard assembly. Solid composition attached to support (11) is shown in phantom.
  • the present invention provides a simple yet highly effective treatment for oral ailments and overcomes a long-felt want or need in a market place for such products.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)

Abstract

Un dispositif pour traiter les troubles buccaux comprend une composition médicinale (17) solide, suçable, fixée à un support (1a) localisant la composition dans la zone buccale. La composition ne peut pas être avalée ni provoquer de suffocation par accident. Plus la composition reste dans la zone buccale, plus elle permet un traitement efficace et les effets secondaires, tels que la nausée qui pourrait survenir au cas où on avale la composition accidentellement, sont évités.
PCT/AU1994/000426 1993-08-03 1994-07-28 Traitement de troubles buccaux WO1995003771A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU73408/94A AU7340894A (en) 1993-08-03 1994-07-28 Treatment of oral ailments

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPM0305 1993-08-03
AUPM030593 1993-08-03

Publications (1)

Publication Number Publication Date
WO1995003771A1 true WO1995003771A1 (fr) 1995-02-09

Family

ID=3777104

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AU1994/000426 WO1995003771A1 (fr) 1993-08-03 1994-07-28 Traitement de troubles buccaux

Country Status (1)

Country Link
WO (1) WO1995003771A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200490A2 (fr) * 1985-05-01 1986-11-05 University Of Utah Research Foundation Compositions pour l'administration non-systémique d'agents sédatifs, analgéniques et anesthésiques
US4863737A (en) * 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
WO1991003237A1 (fr) * 1989-09-05 1991-03-21 University Of Utah Research Foundation Composition et methodes de fabrication de medicaments a dissolution orale
WO1991003236A1 (fr) * 1989-09-05 1991-03-21 University Of Utah Research Foundation Forme de dosage transmucosique
US5048544A (en) * 1990-08-10 1991-09-17 Robert Mascarelli Cigarette substitute
US5085634A (en) * 1990-09-19 1992-02-04 Lackney Albert M Medicament and support
EP0476932A1 (fr) * 1990-09-19 1992-03-25 Albert M. Lackney Médicament et son support

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200490A2 (fr) * 1985-05-01 1986-11-05 University Of Utah Research Foundation Compositions pour l'administration non-systémique d'agents sédatifs, analgéniques et anesthésiques
US4671953A (en) * 1985-05-01 1987-06-09 University Of Utah Research Foundation Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
US4863737A (en) * 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
EP0404205A1 (fr) * 1985-05-01 1990-12-27 University Of Utah Research Foundation Compositions pour l'administration non systémique d'agents sédatifs et analgésiques
WO1991003237A1 (fr) * 1989-09-05 1991-03-21 University Of Utah Research Foundation Composition et methodes de fabrication de medicaments a dissolution orale
WO1991003236A1 (fr) * 1989-09-05 1991-03-21 University Of Utah Research Foundation Forme de dosage transmucosique
AU5521894A (en) * 1989-09-05 1994-04-28 University Of Utah Research Foundation Compositions and methods of manufacture of oral dissolvable medicaments
US5048544A (en) * 1990-08-10 1991-09-17 Robert Mascarelli Cigarette substitute
US5085634A (en) * 1990-09-19 1992-02-04 Lackney Albert M Medicament and support
EP0476932A1 (fr) * 1990-09-19 1992-03-25 Albert M. Lackney Médicament et son support

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