WO1993020864A1 - Pompe d'infusion - Google Patents

Pompe d'infusion Download PDF

Info

Publication number
WO1993020864A1
WO1993020864A1 PCT/DK1993/000121 DK9300121W WO9320864A1 WO 1993020864 A1 WO1993020864 A1 WO 1993020864A1 DK 9300121 W DK9300121 W DK 9300121W WO 9320864 A1 WO9320864 A1 WO 9320864A1
Authority
WO
WIPO (PCT)
Prior art keywords
plunger
cylinder
groove
inlet
outlet
Prior art date
Application number
PCT/DK1993/000121
Other languages
English (en)
Inventor
Ellen Jespersen
Anders Heger
Jens MØLLER-JENSEN
Allan Hemmingsen
Henrik Ljungreen
Jens Ulrik Poulsen
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of WO1993020864A1 publication Critical patent/WO1993020864A1/fr

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B7/00—Piston machines or pumps characterised by having positively-driven valving
    • F04B7/04—Piston machines or pumps characterised by having positively-driven valving in which the valving is performed by pistons and cylinders coacting to open and close intake or outlet ports
    • F04B7/06—Piston machines or pumps characterised by having positively-driven valving in which the valving is performed by pistons and cylinders coacting to open and close intake or outlet ports the pistons and cylinders being relatively reciprocated and rotated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14216—Reciprocating piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16809—Flow controllers by repeated filling and emptying of an intermediate volume

Definitions

  • the invention relates to pumps for repetitively delivering small, well defined amounts of a liquid, e.g. medicine for infusion into a patient's body.
  • Pumps for medicine infusion generally comprise a controlled drive mechanism driving a piston into a cylinder ampoule to press out the requested amount of medicine through a needle or a catheter which may be mounted at the end of the ampoule opposite the piston.
  • the amount of medicine delivered is defined by the distance the piston is pressed into the ampoule.
  • the drive mechanism comprises a piston rod having a length corresponding to the length of the ampoule allowing it to press the piston home to the bottom of the ampoule.
  • the piston rod lies mainly in extension of the ampoule.
  • at least one of the dimensions of the apparatus is at least twice the length of the ampoule.
  • a pump the accuracy of which is independent of the shape of the reservoir for liquid to be pumped, i.e. a conventional cyclic pump with an inlet and outlet, and which pump during a cycle takes in a well defined volume through its inlet and gives off the same well defined volume at its outlet.
  • Another object is to provide a pump which may easily be separated from its drive mechanism to be disposed of when used for a time. This is requested to allow all parts coming into contact with the liquid to be changed when the reservoir is empty. Therefore, the pump must be simple, i.e. made from few parts suited for mass manufacturing.
  • a pump comprising a cylinder having a cylinder wall and an open and a closed end, a rotatable reciprocatable plunger inserted into the open end of the cylinder, an inlet and an outlet opening through the cylinder wall into the inner space of the cylinder, a valve surface at the inner end of the plunger, which surface alternately closes and opens the openings of the inlet and the outlet in the cylfnder wall when the plunger rotates and reciprocates, and means synchronising the rotating and reciprocating movements of the plunger, so that the
  • valve surface opens the outlet and closes ; e inlet when the plunger is moving inwards in the cylinder and opens the inlet and closes the outlet when the plunger is moving outwards in the cylinder.
  • the valve surface may be provided by the surface of the end of the plunger in the cylinder, a sector of this end being cut away along an axial length 0 exceeding the stroke of the plunger.
  • the synchronizing means may be so designed that they impart the plunger a reciprocating movement when it is driven to rotate. Miniaturised rotating drive mechanisms are commonly available.
  • the synchronizing means may comprise a pin guided in a groove, the s groove preferably being provided in a cylindric surface at the outer end of the plunger, and the pin being mounted stiffly connected to the ' cylinder.
  • the groove On the unfolded cylinder surface the groove forms a trapezium curve having "horizontal" parts corresponding to a pure rotation of the plunger and inclined parts correspond ⁇ ing to a combined rotation and axial movement of the plunger, o
  • the outer end of the plunger may have a coupling for engagement with a rotating drive mechanism, this coupling transmitting a rotating movement to the plunger allowing a reciprocating movement of this plunger relative to the drive mechanism.
  • the 5 plunger When the pin is following the "horizontal" parts of the groove, the 5 plunger is maintained in a neutral position during which no transportation of liquid is performed. It is appropriate that the cyclically acting pump starts and ends its cycles with the plunger in such a neutral position. If the drive mechanism is so designed that its output shaft performs one revolution each time a cycle is triggered, the coupling must be so designed that it is ensured that the plunger is in a position o with the pin engaging a "horizontal" part of the groove when the disposable pump is mounted in the infusion apparatus comprising the drive mechanism as a durable part.
  • a coupling comprising at one side a first diametrical element and at the other side a second element having a groove extending along a diameter, the elements being coaxial with the plunger with the first element engaging the groove in the other one, and the axial dimensions of the first element and the groove being so that the reciprocating movement of the plunger is allowed without bringing the first element to the bottom of the groove or out of engagement with this groove.
  • valve mechanism being so designed that the inlet and the outlet are never open at the same time, a free flow through the pump unit is not allowed.
  • the piston may be allowed to be mowed axially outwards so far that the valve surfaces lay open both the inlet and the outlet openings in the cylinder wall.
  • the unit from which the pump receives its rotational driving force may appropriately be so designed that the pump may not be mounted in this unit when its piston is in its above mentioned drawn out position.
  • Figure 1 schematically shows a perspective view of the moving parts of a pump according to the invention
  • Figure 2 schematically shows the rotary and axial position of the plunger in a neutral state of the pump when the plunger is in its innermost position
  • Figure 3 is a schematic view as in Figure 2 when the inlet is just opened
  • Figure 4 is a schematic view of the rotary and axial position of the plunger in a neutral state of the pump with the plunger in its outermost position
  • FIG. 5 is a schematic view as in Figure 4 when the outlet is just opened.
  • an end of a plunger 1 has a sector shaped milling 3 leaving a valve surface 2 for cooperation with inlet and outlet openings in the inner wall of a not shown pump cylinder.
  • the plunger fits rotatably into the cylinder with the valve surface 2 sealingfy engaging the inner wall of this cylinder to close either the inlet
  • the plunger is rotatably driven by a not shown rotary drive mechanism having an output shaft provided with a coupling element 4 having a diametric groove 5.
  • the rotation is transmitted from the drive mechanism to the plunger by the latter having a coupling element 7 with a web 6 engaging the groove 5,
  • the height of the o web 6 and the depth of the groove 5 exceed the stroke of the plunger, so that the coupling element 7 may follow the reciprocal movement of the plunger without the web 6 abutting the bottom of the groove 5 and without withdrawing the web from this groove, i.e. only a rotary movement is transmitted by the coupling.
  • it may as well be the driving element which carries the web and the s coupling element of the plunger which is provided with the groove.
  • this groove describes a closed curve around the element. If the cylindric wall is unfolded, this curve will appear as a trapezium curve with "horizontal" parts representing the two circular parts lying axially and 180° rotationally displaced from o each other, the axially displacement corresponding to the stroke of the plunger.
  • the inclined parts of the trapezium curve represent the helical grooves connecting the ends of one circular part with the ends of the other circular part.
  • the pin will follow the groove, 5 and when the part having an axial component is run through by the pin 9, the element and consequently the plunger is axially displaced relative to the cylinder.
  • Figures 2-5 show schematically sectional views along planes through the inlet and outlet, one plane being perpendicular to the axis and the other along the axis. These views shall be used to illustrate the function of the pump.
  • neutral position i.e. the position from which each pumping cycle starts
  • neutral or starting position may be chosen any position with the piston in its innermost or outermost position.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Details Of Reciprocating Pumps (AREA)
  • Reciprocating Pumps (AREA)

Abstract

Une pompe d'infusion conçue pour la fourniture répétitive de quantités de médicament bien définies, comprend un cylindre comportant une paroi, une extrémité ouverte et une extrémité fermée, un plongueur (1) inséré par l'extrémité ouverte du cylindre, ce plongeur pouvant tourner et effectuer un mouvement de va-et-vient à l'intérieur du cylindre, et un orifice d'entrée et un orifice de sortie à travers la paroi du cylindre. Le plongeur (1) est équipé avec un clapet ou surface qui ouvre et ferme alternativement les orifices d'entrée et de sortie en synchronisation avec le mouvement de va-et-vient du plongeur. Le plongeur (1) est entraîné en rotation par un accouplement permettant son mouvement de va-et-vient; ledit mouvement est provoqué par la rotation du plongeur grâce à une goupille (9) montée de manière rigide sur le cylindre qui s'engage dans une rainure courbe (8) ménagée sur la surface cylindrique (7) solidaire du plongeur (1).
PCT/DK1993/000121 1992-04-10 1993-04-01 Pompe d'infusion WO1993020864A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK0479/92 1992-04-10
DK47992A DK47992D0 (da) 1992-04-10 1992-04-10 Apparat

Publications (1)

Publication Number Publication Date
WO1993020864A1 true WO1993020864A1 (fr) 1993-10-28

Family

ID=8094014

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK1993/000121 WO1993020864A1 (fr) 1992-04-10 1993-04-01 Pompe d'infusion

Country Status (3)

Country Link
AU (1) AU4259893A (fr)
DK (1) DK47992D0 (fr)
WO (1) WO1993020864A1 (fr)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010485A (en) * 1996-09-20 2000-01-04 Novo Nordisk A/S Working cylinder
WO2002087665A1 (fr) * 2001-04-26 2002-11-07 Groening Ruediger Pompe pour administrer des medicaments de façon dosee et regulee dans le temps
EP1803934A1 (fr) * 2005-12-28 2007-07-04 Sensile Medical A.G. Micro-pompe
WO2007084214A1 (fr) * 2006-01-20 2007-07-26 Smiths Medical Asd, Inc. Clapet navette
WO2008141337A1 (fr) * 2007-05-16 2008-11-20 Smiths Medical Asd, Inc. Module de pompe destiné à être utilisé dans un système médical d'administration de fluide
EP2361646A1 (fr) * 2008-09-12 2011-08-31 Roche Diagnostics GmbH Unité de dosage et dispositif de perfusion ambulatoire comportant l'unité de dosage
US8790316B2 (en) 2007-03-15 2014-07-29 Roche Diagnostics International Ag Dosing device for an infusion system and method thereof
US9057363B2 (en) 2007-12-10 2015-06-16 Bayer Medical Care, Inc. Continuous fluid delivery system
EP2962714A1 (fr) * 2014-07-02 2016-01-06 Becton Dickinson and Company Pompe de dosage de came interne
JP2017513577A (ja) * 2014-04-07 2017-06-01 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ インスリンパッチのための回転計量ポンプ
WO2019204149A1 (fr) * 2018-04-19 2019-10-24 Becton, Dickinson And Company Seringue à auto-pompage
US10507319B2 (en) 2015-01-09 2019-12-17 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
WO2021041184A1 (fr) * 2019-08-26 2021-03-04 Eli Lilly And Company Sous-systèmes de pompe à piston rotatif
CN113167258A (zh) * 2018-11-28 2021-07-23 英赛罗公司 药物输送往复泵系统和阀组件
US11229736B2 (en) 2018-06-06 2022-01-25 Insulet Corporation Linear shuttle pump for drug delivery
US11229741B2 (en) 2012-03-30 2022-01-25 Insulet Corporation Fluid delivery device, transcutaneous access tool and fluid drive mechanism for use therewith
US11229740B2 (en) 2017-03-07 2022-01-25 Insulet Corporation Very high volume user filled drug delivery device
US11280327B2 (en) 2017-08-03 2022-03-22 Insulet Corporation Micro piston pump
US11369735B2 (en) 2019-11-05 2022-06-28 Insulet Corporation Component positioning of a linear shuttle pump
US11439765B2 (en) 2016-08-14 2022-09-13 Insulet Corporation Variable fill drug delivery device
US11633541B2 (en) 2017-01-19 2023-04-25 Insulet Corporation Cartridge hold-up volume reduction
US11672917B2 (en) 2018-05-31 2023-06-13 Insulet Corporation Drug cartridge with drive system
US11786668B2 (en) 2017-09-25 2023-10-17 Insulet Corporation Drug delivery devices, systems, and methods with force transfer elements
US11980746B2 (en) 2019-04-12 2024-05-14 Becton, Dickinson And Company Self-pumping syringe

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2634318A1 (de) * 1975-07-31 1977-02-17 Octagon Med Prod Pumpe, vorzugsweise zum dosieren und kalibrieren
US4479759A (en) * 1979-12-13 1984-10-30 Vernon Zeitz Valveless, positive displacement pump
EP0319274A1 (fr) * 1987-12-01 1989-06-07 Pacesetter Infusion Limited doing business as Minimed Technologies Système d'entraînement mécanique pour un système de perfusion de médicaments
EP0346611A2 (fr) * 1988-05-18 1989-12-20 Groninger & Co. Gmbh Procédé de stérilisation par chaleur des pompes
US4968230A (en) * 1988-05-31 1990-11-06 Textron Inc. Lubricating-oil pump control
EP0512688A2 (fr) * 1991-04-15 1992-11-11 Baxter International Inc. Pompe de dosage

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2634318A1 (de) * 1975-07-31 1977-02-17 Octagon Med Prod Pumpe, vorzugsweise zum dosieren und kalibrieren
US4479759A (en) * 1979-12-13 1984-10-30 Vernon Zeitz Valveless, positive displacement pump
EP0319274A1 (fr) * 1987-12-01 1989-06-07 Pacesetter Infusion Limited doing business as Minimed Technologies Système d'entraînement mécanique pour un système de perfusion de médicaments
EP0346611A2 (fr) * 1988-05-18 1989-12-20 Groninger & Co. Gmbh Procédé de stérilisation par chaleur des pompes
US4968230A (en) * 1988-05-31 1990-11-06 Textron Inc. Lubricating-oil pump control
EP0512688A2 (fr) * 1991-04-15 1992-11-11 Baxter International Inc. Pompe de dosage

Cited By (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010485A (en) * 1996-09-20 2000-01-04 Novo Nordisk A/S Working cylinder
WO2002087665A1 (fr) * 2001-04-26 2002-11-07 Groening Ruediger Pompe pour administrer des medicaments de façon dosee et regulee dans le temps
CN102691637A (zh) * 2005-12-28 2012-09-26 森西勒Pat股份公司 微型泵
EP1803934A1 (fr) * 2005-12-28 2007-07-04 Sensile Medical A.G. Micro-pompe
WO2007074363A2 (fr) * 2005-12-28 2007-07-05 Sensile Pat Ag Micropompe
WO2007074363A3 (fr) * 2005-12-28 2007-10-04 Sensile Medical A G Micropompe
CN102691637B (zh) * 2005-12-28 2015-06-17 森西勒Pat股份公司 微型泵
US8282366B2 (en) 2005-12-28 2012-10-09 Sensile Pat Ag Micropump
WO2007084214A1 (fr) * 2006-01-20 2007-07-26 Smiths Medical Asd, Inc. Clapet navette
US7637279B2 (en) 2006-01-20 2009-12-29 Smiths Medical Asd, Inc. Shuttle valve
US10029046B2 (en) 2007-03-15 2018-07-24 Roche Diabetes Care, Inc. Dosing device for an infusion system and method thereof
EP3012600A1 (fr) * 2007-03-15 2016-04-27 F. Hoffmann-La Roche AG Dispositif de dosage pour un système d'infusion
US10034977B2 (en) 2007-03-15 2018-07-31 Roche Diabetes Care, Inc. Dosing device for an infusion system and method thereof
US10034983B2 (en) 2007-03-15 2018-07-31 Roche Diabetes Care, Inc. Dosing device for an infusion system and method thereof
EP3258223A1 (fr) * 2007-03-15 2017-12-20 F. Hoffmann-La Roche AG Dispositif de dosage pour un système d'infusion
US9687604B2 (en) 2007-03-15 2017-06-27 Roche Diagnostics International Ag Dosing device for an infusion system and method thereof
US8790316B2 (en) 2007-03-15 2014-07-29 Roche Diagnostics International Ag Dosing device for an infusion system and method thereof
US7951112B2 (en) 2007-05-16 2011-05-31 Smiths Medical Asd, Inc. Pump module for use in a medical fluid dispensing system
JP2010527273A (ja) * 2007-05-16 2010-08-12 スミス・メディカル・エイエスディ・インコーポレーテッド 薬液投薬システムにおける使用のためのポンプモジュール
US8142397B2 (en) 2007-05-16 2012-03-27 Smiths Medical Asd, Inc. Pump module method for a medical fluid dispensing system
WO2008141337A1 (fr) * 2007-05-16 2008-11-20 Smiths Medical Asd, Inc. Module de pompe destiné à être utilisé dans un système médical d'administration de fluide
US9057363B2 (en) 2007-12-10 2015-06-16 Bayer Medical Care, Inc. Continuous fluid delivery system
US9119911B2 (en) 2008-09-12 2015-09-01 Roche Diagnostics International Ag Dosing unit, ambulatory infusion device comprising dosing unit and method for operating a dosing unit
EP2361646A1 (fr) * 2008-09-12 2011-08-31 Roche Diagnostics GmbH Unité de dosage et dispositif de perfusion ambulatoire comportant l'unité de dosage
US8500700B2 (en) 2008-09-12 2013-08-06 Roche Diagnostics International Ag Dosing unit, ambulatory infusion device comprising dosing unit and method for operating a dosing unit
US8469930B2 (en) 2008-09-12 2013-06-25 Roche Diagnostics International Ag Dosing unit, ambulatory infusion device comprising dosing unit and method for operating a dosing unit
US11229741B2 (en) 2012-03-30 2022-01-25 Insulet Corporation Fluid delivery device, transcutaneous access tool and fluid drive mechanism for use therewith
JP2017513577A (ja) * 2014-04-07 2017-06-01 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ インスリンパッチのための回転計量ポンプ
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
EP2962714A1 (fr) * 2014-07-02 2016-01-06 Becton Dickinson and Company Pompe de dosage de came interne
US11491318B2 (en) 2015-01-09 2022-11-08 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
US10507319B2 (en) 2015-01-09 2019-12-17 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
US11439765B2 (en) 2016-08-14 2022-09-13 Insulet Corporation Variable fill drug delivery device
US11497856B2 (en) 2016-08-14 2022-11-15 Insulet Corporation Drug delivery device with indicator
US11633541B2 (en) 2017-01-19 2023-04-25 Insulet Corporation Cartridge hold-up volume reduction
US11229740B2 (en) 2017-03-07 2022-01-25 Insulet Corporation Very high volume user filled drug delivery device
US11280327B2 (en) 2017-08-03 2022-03-22 Insulet Corporation Micro piston pump
US11786668B2 (en) 2017-09-25 2023-10-17 Insulet Corporation Drug delivery devices, systems, and methods with force transfer elements
JP2022095963A (ja) * 2018-04-19 2022-06-28 ベクトン・ディキンソン・アンド・カンパニー 自己ポンプ式注射器
WO2019204149A1 (fr) * 2018-04-19 2019-10-24 Becton, Dickinson And Company Seringue à auto-pompage
CN115120811A (zh) * 2018-04-19 2022-09-30 贝克顿·迪金森公司 自动泵送注射器
JP2021519623A (ja) * 2018-04-19 2021-08-12 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 自己ポンプ式注射器
US11672917B2 (en) 2018-05-31 2023-06-13 Insulet Corporation Drug cartridge with drive system
US11229736B2 (en) 2018-06-06 2022-01-25 Insulet Corporation Linear shuttle pump for drug delivery
CN113167258A (zh) * 2018-11-28 2021-07-23 英赛罗公司 药物输送往复泵系统和阀组件
US11446435B2 (en) * 2018-11-28 2022-09-20 Insulet Corporation Drug delivery shuttle pump system and valve assembly
JP2022510238A (ja) * 2018-11-28 2022-01-26 インスレット コーポレイション 薬物送達シャトルポンプシステムと弁アセンブリ
US11980746B2 (en) 2019-04-12 2024-05-14 Becton, Dickinson And Company Self-pumping syringe
CN114450046A (zh) * 2019-08-26 2022-05-06 伊莱利利公司 旋转柱塞泵子系统
WO2021041184A1 (fr) * 2019-08-26 2021-03-04 Eli Lilly And Company Sous-systèmes de pompe à piston rotatif
US11344669B2 (en) 2019-08-26 2022-05-31 Eli Lilly And Company Rotary plunger pump subsystems
AU2020340265B2 (en) * 2019-08-26 2023-06-15 Eli Lilly And Company Rotary plunger pump subsystems
JP2021529069A (ja) * 2019-08-26 2021-10-28 イーライ リリー アンド カンパニー 回転プランジャポンプサブシステム
CN114450046B (zh) * 2019-08-26 2023-12-08 伊莱利利公司 旋转柱塞泵子系统
US11369735B2 (en) 2019-11-05 2022-06-28 Insulet Corporation Component positioning of a linear shuttle pump

Also Published As

Publication number Publication date
AU4259893A (en) 1993-11-18
DK47992D0 (da) 1992-04-10

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