WO1993000056A1 - A bandage or dressing for covering wounds - Google Patents

A bandage or dressing for covering wounds Download PDF

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Publication number
WO1993000056A1
WO1993000056A1 PCT/DK1992/000197 DK9200197W WO9300056A1 WO 1993000056 A1 WO1993000056 A1 WO 1993000056A1 DK 9200197 W DK9200197 W DK 9200197W WO 9300056 A1 WO9300056 A1 WO 9300056A1
Authority
WO
WIPO (PCT)
Prior art keywords
adhesive sheet
bandage
ditches
skin
dressing
Prior art date
Application number
PCT/DK1992/000197
Other languages
French (fr)
Inventor
Peter Boman Samuelsen
Original Assignee
Coloplast A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coloplast A/S filed Critical Coloplast A/S
Priority to DE69213014T priority Critical patent/DE69213014T2/en
Priority to JP5501300A priority patent/JPH06508775A/en
Priority to US08/167,983 priority patent/US5486158A/en
Priority to EP92915090A priority patent/EP0591440B1/en
Publication of WO1993000056A1 publication Critical patent/WO1993000056A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/0246—Adhesive plasters or dressings characterised by the skin adhering layer
    • A61F13/025—Adhesive plasters or dressings characterised by the skin adhering layer having a special distribution arrangement of the adhesive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/0203—Adhesive plasters or dressings having a fluid handling member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/0203—Adhesive plasters or dressings having a fluid handling member
    • A61F13/0213—Adhesive plasters or dressings having a fluid handling member the fluid handling member being a layer of hydrocoloid, gel forming material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/0259—Adhesive plasters or dressings characterised by the release liner covering the skin adhering layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/51—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the outer layers
    • A61F13/514—Backsheet, i.e. the impermeable cover or layer furthest from the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00519—Plasters use for treating burn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00727—Plasters means for wound humidity control
    • A61F2013/00748—Plasters means for wound humidity control with hydrocolloids or superabsorbers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00727—Plasters means for wound humidity control
    • A61F2013/00757—Plasters means for wound humidity control with absorbent adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00855—Plasters pervious to air or vapours
    • A61F2013/00885—Plasters pervious to air or vapours impervious, i.e. occlusive bandage
    • A61F2013/00893—Plasters pervious to air or vapours impervious, i.e. occlusive bandage viscoelastic oil-elastomer gel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00902—Plasters containing means
    • A61F2013/0091—Plasters containing means with disinfecting or anaesthetics means, e.g. anti-mycrobic

Definitions

  • the present invention refers to a skin-friendly bandage or dressing for covering wounds, burns or similar damages of the human skin, or ostomi openings.
  • a skin-friendly dressing comprising a water soluble or water swellable hydrocolloid, a water-insoluble, viscous elastomeric binder and optionally also a tackifying resin.
  • This known dressing is formed as a sealing pad having bevelled outer edges and optionally also, if annular, a bevelled inner edge.
  • An object of the present invention is to provide a bandage or wound dressing having a high moisture absorbing capa ⁇ city and simultaneously a high degree of flexibility for covering surface areas of the human body.
  • the skin-friendly bandage or dressing comprises a moisture absorbing, to skin and mucous membranes adhering adhesive sheet, consisting of a layer of a water swellable colloid which is dispersed in or mixed with a water insoluble viscous elastomer binder and, if desired, usual auxiliary materials, the adhesive sheet at one outwardly directed surface being firmly connected to a non-adhesive water impervious cover layer, and the other against the skin or mucous membrane directed ad ⁇ hesive surface being provided with a removable protecting sheet.
  • the bandage or wound dressing is specificly characterized in that the adhesive sheet is provided with one or several grooves or ditches that fully or partly surround the central part of the adhesive sheet.
  • the swellable colloid particles preferably consist of one or more water soluble or water swellable hydrocolloid polymers or gums. Suitable examples are carboxy ethylcellulose, dextran, pectin, guar gum and polyvinylalkohol. Further examples of such materials are mentioned in US 4 867 748, EP 0 122 344.
  • the elastomer binder acting as a medium for dispersing the hydrocolloid particles, is any known water-insoluble elastomeric substance, preferably a polymer or copolymer. Suitable examples are polyisobutylene, silicone rubber, acrylonitride rubber, polyurethane etc. Further examples may be derived from the above mentioned EP 0 122 344.
  • any common used auxiliary material may be included as a component of the dressing, such as antioxidants, for example butylated hydroxyamisole or hydroxytoluene, deodorants such as chlorophyllins, or perfume agents. It is also common practice to add pharmacologically active ingredients in the adhesive composition, such as antibiotic or antimicrobial agents, such as neomycin, an antiseptic agents such as povidone iodine, and/or an antiinflammatory agent such as hydrocortisone or triamcinolone acetomide.
  • antibiotic or antimicrobial agents such as neomycin
  • an antiseptic agents such as povidone iodine
  • an antiinflammatory agent such as hydrocortisone or triamcinolone acetomide.
  • the impervious cover layer may consist of any known useful material for the purpose. Examples of such materials are any film forming polymer, such as polyethylene, polypro ⁇ pylene, polyester, pol vinylchloride, polyvinyliden- chloride, polyvinylacetate, polyamide, polyvinylether and polyurethane.
  • the impervious cover layer may also be a foam, such as polyurethane foam or polyether foam.
  • the bandage or wound dressing may, according to an embodiment of the invention, have a hole in the central part.
  • the groove's or ditches may preferably have such a depth that the thickness of the sheet at the bottom of the ditch is less than 1/4 of the thickness of the sheet between the ditches.
  • the width of the grooves or ditches is up to three times the depth and, preferably, the width has the same size as the depth. A maximum of flexibility is thus obtained.
  • the grooves or ditches impart highly increased flexibility to the dressing.
  • Fig. 1, 4 and 5 are three different embodiments of the bandage according to the invention, seen from above,
  • Fig. 2, 3 and 6 illustrate various forms of grooves or ditches in the bandage
  • Fig. 7 illustrates a special embodiment in which only a distal part of the bandage has grooves.
  • the bandage illustrated in fig. 1 consists of a circular sheet with an outer edge 1 and two grooves 2, 3.
  • the central part 4 has a uniform maximum thickness.
  • the grooves may have different profiles such as V- or U-shapes.
  • An impervious cover layer 6 consisting of a polymer film or a thin foam layer is placed on top of the outer surface.
  • the surface to be placed against the skin is provided with adhesive layer 8 covered by a protective removable film 7.
  • One or two concentric grooves improves considerably the resistance to radial swelling. This property may be measured by a method described below.
  • the central part 4 may be a hole as illustrated in fig. 4.
  • This embodiment is suitable as bandage for ostomi open ⁇ ings. Increased flexibility is obtained due to cencentric ditches 3 as well as radial ditches 2. Such a bandage can be rather thick having a high absorption capacity and still being highly flexible.
  • the bandage shown in fig. 5 has an elliptical outer edge 1.
  • the bandage shown in fig. 7 is intended to be placed at a vertical surface of a body area, the distal part directed downward in order to minimize swelling in the downward direction.
  • the dressings according to the invention may be manufactured in various ways, e.g. by a die-casting process or a pressing process. An adequate method of manufacturing the dressing is disclosed by US 4 867 748.
  • An apparatus of a sheet of glass (25 x 25 cm) with a cen ⁇ tral hole of 20 mm is connected to a reservoir of water via a tube mounted on to the said hole.
  • the product to be tested is applied with the hole as centrum.
  • Physiological saline is introduced to the product adhering to the glass sheet by elevating the reservoir for said saline to a position above the product.
  • a pressure of 2-10 cm of water column is applied to the product and the radially swelling from the hole out through the product may be determined.
  • the test is perfomed at 37 °C and readings are taken at the times; 6 hours, 24 hours, 2, 3 and 4 days.
  • the glass plate is placed horizontally in the test.
  • a test product from the category of hydrocolloid dressings and with a content of 40% particles of sodiumcarboxy- methyl-cellulose dispersed in an elastomeric binder con- sisting of polyisobutylene and covered by a polyurethane film of 30 u was tested as a plane sheet and formed with 2 grooves as shown in fig. 1.
  • the grooves are concentric and centrally placed with deformation diameters of 24 mm and 34 mm.
  • the radial swellings at 12 hours are identical for the two dressings. However, when passing the first deformation after 24 hours a decrease in radial swelling velocity of 13% is observed for the deformed version and this decrease has after further 3 days further increased to a level of 30%.

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A skin-friendly dressing, comprising a moisture absorbing, to skin and mucous membranes adhering adhesive sheet, consisting of a layer of a water swellable colloid (10) which is dispersed in or mixed with a water insoluble viscous elastomer binder (9) and, if desired, usual auxiliary materials, the adhesive sheet at one outwardly directed surface being firmly connected to a non-adhesive water impervious cover layer (6), and at the other against the skin or mucous membrane directed surface of the adhesive sheet being provided with a removable protecting sheet (7). The adhesive sheet is provided with one or several grooves or ditches (2, 3) that fully or partly surround a central part (4) of the adhesive sheet. The dressing has a high moisture absorbing capacity, a high degree of flexibility and a good integrity.

Description

A bandage or dressing for covering wounds
The present invention refers to a skin-friendly bandage or dressing for covering wounds, burns or similar damages of the human skin, or ostomi openings.
From US Patent No. 4 867 748 is known a skin-friendly dressing comprising a water soluble or water swellable hydrocolloid, a water-insoluble, viscous elastomeric binder and optionally also a tackifying resin. This known dressing is formed as a sealing pad having bevelled outer edges and optionally also, if annular, a bevelled inner edge.
The dressings described in this and other similar patents are rather stiff as they must have a considerable thick¬ ness in order to contain a sufficient amount of moisture absorbing materials.
An object of the present invention is to provide a bandage or wound dressing having a high moisture absorbing capa¬ city and simultaneously a high degree of flexibility for covering surface areas of the human body.
It is also an object of the invention to provide a bandage or wound dressing comprising a medicament or a similar physiologically active material that may be transferred to the skin or mucous membranes to which the bandage or dressing is adhered.
According to the invention it has been found that a sur¬ prisingly high degree of flexibility may be obtained without compromizing the integrity and the absorbing properties when the bandage or wound dressing is provided with grooves or ditches. The skin-friendly bandage or dressing according to the in¬ vention comprises a moisture absorbing, to skin and mucous membranes adhering adhesive sheet, consisting of a layer of a water swellable colloid which is dispersed in or mixed with a water insoluble viscous elastomer binder and, if desired, usual auxiliary materials, the adhesive sheet at one outwardly directed surface being firmly connected to a non-adhesive water impervious cover layer, and the other against the skin or mucous membrane directed ad¬ hesive surface being provided with a removable protecting sheet. The bandage or wound dressing is specificly characterized in that the adhesive sheet is provided with one or several grooves or ditches that fully or partly surround the central part of the adhesive sheet.
The swellable colloid particles preferably consist of one or more water soluble or water swellable hydrocolloid polymers or gums. Suitable examples are carboxy ethylcellulose, dextran, pectin, guar gum and polyvinylalkohol. Further examples of such materials are mentioned in US 4 867 748, EP 0 122 344.
The elastomer binder, acting as a medium for dispersing the hydrocolloid particles, is any known water-insoluble elastomeric substance, preferably a polymer or copolymer. Suitable examples are polyisobutylene, silicone rubber, acrylonitride rubber, polyurethane etc. Further examples may be derived from the above mentioned EP 0 122 344.
If desired, any common used auxiliary material may be included as a component of the dressing, such as antioxidants, for example butylated hydroxyamisole or hydroxytoluene, deodorants such as chlorophyllins, or perfume agents. It is also common practice to add pharmacologically active ingredients in the adhesive composition, such as antibiotic or antimicrobial agents, such as neomycin, an antiseptic agents such as povidone iodine, and/or an antiinflammatory agent such as hydrocortisone or triamcinolone acetomide.
Further examples of such auxiliary are enumerated in the literature, see for example EP 0 122 344, EP 0 340 945, US 3 972 328, and US 4 867 748.
The impervious cover layer may consist of any known useful material for the purpose. Examples of such materials are any film forming polymer, such as polyethylene, polypro¬ pylene, polyester, pol vinylchloride, polyvinyliden- chloride, polyvinylacetate, polyamide, polyvinylether and polyurethane. The impervious cover layer may also be a foam, such as polyurethane foam or polyether foam.
The bandage or wound dressing may, according to an embodiment of the invention, have a hole in the central part.
The groove's or ditches may preferably have such a depth that the thickness of the sheet at the bottom of the ditch is less than 1/4 of the thickness of the sheet between the ditches. The width of the grooves or ditches is up to three times the depth and, preferably, the width has the same size as the depth. A maximum of flexibility is thus obtained.
The grooves or ditches impart highly increased flexibility to the dressing.
The invention shall be further described in connection with the drawing, where
Fig. 1, 4 and 5 are three different embodiments of the bandage according to the invention, seen from above,
Fig. 2, 3 and 6 illustrate various forms of grooves or ditches in the bandage, and
Fig. 7 illustrates a special embodiment in which only a distal part of the bandage has grooves.
The bandage illustrated in fig. 1 consists of a circular sheet with an outer edge 1 and two grooves 2, 3. The central part 4 has a uniform maximum thickness. As shown in fig. 2, 3 and 6 the grooves may have different profiles such as V- or U-shapes. An impervious cover layer 6 consisting of a polymer film or a thin foam layer is placed on top of the outer surface. The surface to be placed against the skin is provided with adhesive layer 8 covered by a protective removable film 7.
One or two concentric grooves improves considerably the resistance to radial swelling. This property may be measured by a method described below.
The central part 4 may be a hole as illustrated in fig. 4.
This embodiment is suitable as bandage for ostomi open¬ ings. Increased flexibility is obtained due to cencentric ditches 3 as well as radial ditches 2. Such a bandage can be rather thick having a high absorption capacity and still being highly flexible.
The bandage shown in fig. 5 has an elliptical outer edge 1. The bandage shown in fig. 7 is intended to be placed at a vertical surface of a body area, the distal part directed downward in order to minimize swelling in the downward direction. The dressings according to the invention may be manufactured in various ways, e.g. by a die-casting process or a pressing process. An adequate method of manufacturing the dressing is disclosed by US 4 867 748.
Method of determining radial swelling
An apparatus of a sheet of glass (25 x 25 cm) with a cen¬ tral hole of 20 mm is connected to a reservoir of water via a tube mounted on to the said hole. At the side oppo¬ site to the tube of the sheet of glass the product to be tested is applied with the hole as centrum. Physiological saline is introduced to the product adhering to the glass sheet by elevating the reservoir for said saline to a position above the product. A pressure of 2-10 cm of water column is applied to the product and the radially swelling from the hole out through the product may be determined. The test is perfomed at 37 °C and readings are taken at the times; 6 hours, 24 hours, 2, 3 and 4 days. The glass plate is placed horizontally in the test.
The invention is further illustrated by the following examples.
Example 1
A test product from the category of hydrocolloid dressings and with a content of 40% particles of sodiumcarboxy- methyl-cellulose dispersed in an elastomeric binder con- sisting of polyisobutylene and covered by a polyurethane film of 30 u was tested as a plane sheet and formed with 2 grooves as shown in fig. 1. The grooves are concentric and centrally placed with deformation diameters of 24 mm and 34 mm.
The radial swellings at 12 hours are identical for the two dressings. However, when passing the first deformation after 24 hours a decrease in radial swelling velocity of 13% is observed for the deformed version and this decrease has after further 3 days further increased to a level of 30%.
Example 2
A product configuration comprising the same materials as mentioned in example 1 and especially intended for leg ulcers was investigated. Here a considerable radial swelling component exists due to gravity. This means that the distal or downward part of a hydrocolloid dressing will swell more quickly than the rest of the product and hence give rise to product change although there may be considerable swelling capacity left in the product in total. By only deforming the distal part of the product by compartments as in the figure 7 and testing it by described method placing the glass sheet vertically the period before distal leakage is improved with 18-23% when the hydrocolloid dressing is deformed compared to the identified control without deformation.

Claims

P a t e n t C l a i m s :
1. A skin-friendly dressing, comprising a moisture ab- sorbing, to skin and mucous membranes adhering adhesive sheet, consisting of a layer of a water swellable colloid (10) which is dispersed in or mixed with a water insoluble viscous elastomer binder (9) and, if desired, usual auxiliary materials, the adhesive sheet at one outwardly directed surface being firmly connected to a non-adhesive water impervious cover layer (6), and at the other against the skin or mucous membrane directed surface of the adhesive sheet being provided with a removable protecting sheet (7), c h a r a c t e r i z e d in that the adhesive sheet is provided with one or several grooves or ditches
(2, 3) that fully or partly surround a central part (4) of the adhesive sheet.
2. A bandage or dressing according to claim 1, c h a r a c t e r i z e d in that the central part (4) is a hole.
3. A bandage or dressing according to claim 1, c h a r a c t e r i z e d in that at least one of the grooves or ditches is arranged concentric around the central part (4).
4. A bandage or dressing according to claim 1, c h a r a c t e r i z e d in that at least some of the grooves or ditches are arranged radially outwardly from the central part (4).
5. A bandage or dressing according to any of the preceding claims, c h a r a c t e r i z e d in that said grooves or ditches have such a depth that the thickness of the sheet at the bottom of the ditch is less than of the thickness of the sheet between the ditches.
PCT/DK1992/000197 1991-06-24 1992-06-23 A bandage or dressing for covering wounds WO1993000056A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE69213014T DE69213014T2 (en) 1991-06-24 1992-06-23 Bandage or bandage to cover wounds
JP5501300A JPH06508775A (en) 1991-06-24 1992-06-23 bandages to cover wounds
US08/167,983 US5486158A (en) 1991-06-24 1992-06-23 Grooved hydrocolloidal dressing
EP92915090A EP0591440B1 (en) 1991-06-24 1992-06-23 A bandage or dressing for covering wounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK911227A DK122791D0 (en) 1991-06-24 1991-06-24 wound dressing
DK1227/91 1991-06-24

Publications (1)

Publication Number Publication Date
WO1993000056A1 true WO1993000056A1 (en) 1993-01-07

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ID=8102423

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK1992/000197 WO1993000056A1 (en) 1991-06-24 1992-06-23 A bandage or dressing for covering wounds

Country Status (7)

Country Link
US (1) US5486158A (en)
EP (1) EP0591440B1 (en)
JP (1) JPH06508775A (en)
KR (1) KR100222507B1 (en)
DE (1) DE69213014T2 (en)
DK (1) DK122791D0 (en)
WO (1) WO1993000056A1 (en)

Cited By (29)

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JPH06508775A (en) 1994-10-06
DE69213014D1 (en) 1996-09-26
US5486158A (en) 1996-01-23
DK122791D0 (en) 1991-06-24
EP0591440B1 (en) 1996-08-21
KR930000117A (en) 1993-01-15
KR100222507B1 (en) 1999-10-01
DE69213014T2 (en) 1997-01-23
EP0591440A1 (en) 1994-04-13

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