WO1990012788A3 - ACETALISCH GESCHÜTZTE ENANTIOMERENREINE α-ARYLALKANCARBONSÄUREN, DEREN HERSTELLUNG UND VERWENDUNG - Google Patents

ACETALISCH GESCHÜTZTE ENANTIOMERENREINE α-ARYLALKANCARBONSÄUREN, DEREN HERSTELLUNG UND VERWENDUNG Download PDF

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Publication number
WO1990012788A3
WO1990012788A3 PCT/AT1990/000038 AT9000038W WO9012788A3 WO 1990012788 A3 WO1990012788 A3 WO 1990012788A3 AT 9000038 W AT9000038 W AT 9000038W WO 9012788 A3 WO9012788 A3 WO 9012788A3
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WO
WIPO (PCT)
Prior art keywords
acetalically
enantiomer
pure
protected
production
Prior art date
Application number
PCT/AT1990/000038
Other languages
English (en)
French (fr)
Other versions
WO1990012788A2 (de
Inventor
Christian R Noe
Max Knollmueller
Marion Letschnig
Armin Holzner
Original Assignee
Christian R Noe
Max Knollmueller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christian R Noe, Max Knollmueller filed Critical Christian R Noe
Publication of WO1990012788A2 publication Critical patent/WO1990012788A2/de
Publication of WO1990012788A3 publication Critical patent/WO1990012788A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Die Erfindung betrifft acetalisch geschützte enantiomerenreine α-Arylalkancarbonsäuren der allgemeinen Formel (I), in welcher A, B, C und D Wasserstoff oder eine Methylgruppe in beliebiger Kombination, m und n die Zahlen 0, 1 oder 2 bedeutet, wobei die Summe aus m und n 1 oder 2 sein muss und in welcher Ar substituiertes oder unsubstituiertes Aryl und substituiertes oder unsubstituiertes Heteroaryl in beliebiger Kombination bedeutet, und in welcher R1 verzweigtes und unverzweigtes Alkyl, vorzugsweise nieder Alkyl bedeutet, deren Herstellung und Verwendung.
PCT/AT1990/000038 1989-04-24 1990-04-24 ACETALISCH GESCHÜTZTE ENANTIOMERENREINE α-ARYLALKANCARBONSÄUREN, DEREN HERSTELLUNG UND VERWENDUNG WO1990012788A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT96989 1989-04-24
ATA969/89 1989-04-24

Publications (2)

Publication Number Publication Date
WO1990012788A2 WO1990012788A2 (de) 1990-11-01
WO1990012788A3 true WO1990012788A3 (de) 1990-12-13

Family

ID=3503968

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT1990/000038 WO1990012788A2 (de) 1989-04-24 1990-04-24 ACETALISCH GESCHÜTZTE ENANTIOMERENREINE α-ARYLALKANCARBONSÄUREN, DEREN HERSTELLUNG UND VERWENDUNG

Country Status (2)

Country Link
AU (1) AU5527190A (de)
WO (1) WO1990012788A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT396686B (de) * 1992-04-13 1993-11-25 Christian Dr Noe Reagention zur razemattrennung, verfahren zu ihrer herstellung und verwendung

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH291375A (de) * 1950-12-13 1953-06-15 Hommels S Haematogen Ag Verfahren zur Herstellung von a-Phenylbuttersäure-diäthylaminoäthylester.
US3349114A (en) * 1963-05-17 1967-10-24 Hommel Ag Diethylaminoethoxyethyl ester of alpha-phenylbutyric acid and salts thereof
EP0083335A1 (de) * 1981-12-18 1983-07-06 Christian Dipl.-Ing. Dr. Noe Chirale, optisch aktive Verbindungen, Verfahren zu ihrer Herstellung und Verwendung dieser Verbindungen für den Schutz funktioneller -OH, -SH, -NH-Gruppen, zur Racemattrennung, zur Herstellung optisch aktiver Imidoesterhydrochloride sowie optisch aktiver Ester, zur Herstellung optisch angereicherter Alkohole und zur Herstellung optisch aktiver Verbindungen durch asymmetrische Induktion

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH291375A (de) * 1950-12-13 1953-06-15 Hommels S Haematogen Ag Verfahren zur Herstellung von a-Phenylbuttersäure-diäthylaminoäthylester.
US3349114A (en) * 1963-05-17 1967-10-24 Hommel Ag Diethylaminoethoxyethyl ester of alpha-phenylbutyric acid and salts thereof
EP0083335A1 (de) * 1981-12-18 1983-07-06 Christian Dipl.-Ing. Dr. Noe Chirale, optisch aktive Verbindungen, Verfahren zu ihrer Herstellung und Verwendung dieser Verbindungen für den Schutz funktioneller -OH, -SH, -NH-Gruppen, zur Racemattrennung, zur Herstellung optisch aktiver Imidoesterhydrochloride sowie optisch aktiver Ester, zur Herstellung optisch angereicherter Alkohole und zur Herstellung optisch aktiver Verbindungen durch asymmetrische Induktion

Also Published As

Publication number Publication date
WO1990012788A2 (de) 1990-11-01
AU5527190A (en) 1990-11-16

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