WO1990012105A3 - Production of amino acids by methylotrophic bacillus - Google Patents

Production of amino acids by methylotrophic bacillus Download PDF

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Publication number
WO1990012105A3
WO1990012105A3 PCT/US1990/001908 US9001908W WO9012105A3 WO 1990012105 A3 WO1990012105 A3 WO 1990012105A3 US 9001908 W US9001908 W US 9001908W WO 9012105 A3 WO9012105 A3 WO 9012105A3
Authority
WO
WIPO (PCT)
Prior art keywords
amino acids
production
methylotrophic bacillus
methylotrophic
bacillus
Prior art date
Application number
PCT/US1990/001908
Other languages
French (fr)
Other versions
WO1990012105A2 (en
Inventor
Richard S Hanson
Michael C Flickinger
Frederick J Schendel
Michael V Guettler
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Priority to CA002030529A priority Critical patent/CA2030529C/en
Priority to EP90906690A priority patent/EP0422187B1/en
Priority to DE69022522T priority patent/DE69022522T2/en
Priority to BR909006409A priority patent/BR9006409A/en
Publication of WO1990012105A2 publication Critical patent/WO1990012105A2/en
Publication of WO1990012105A3 publication Critical patent/WO1990012105A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A method of producing amino acids by culturing an amino acid auxotroph of a biologically pure strain of a type I methylotrophic bacterium of the genus Bacillus which exhibits sustained growth at 50°C using methanol as a carbon and energy source and requiring vitamin B12 and biotin is provided.
PCT/US1990/001908 1989-04-10 1990-04-09 Production of amino acids by methylotrophic bacillus WO1990012105A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002030529A CA2030529C (en) 1989-04-10 1990-04-09 Production of amino acids by methylotrophic bacillus
EP90906690A EP0422187B1 (en) 1989-04-10 1990-04-09 Production of amino acids by methylotrophic bacillus
DE69022522T DE69022522T2 (en) 1989-04-10 1990-04-09 PRODUCTION OF AMINO ACIDS BY METHYLOTROPHIC BAZILLES.
BR909006409A BR9006409A (en) 1989-04-10 1990-04-09 PRODUCTION OF AMINO ACIDS BY METHYLOTROPHIC BACYL

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33569189A 1989-04-10 1989-04-10
US335,691 1989-04-10
US35143689A 1989-05-12 1989-05-12
US351,436 1989-05-12

Publications (2)

Publication Number Publication Date
WO1990012105A2 WO1990012105A2 (en) 1990-10-18
WO1990012105A3 true WO1990012105A3 (en) 1990-11-15

Family

ID=26989842

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1990/001908 WO1990012105A2 (en) 1989-04-10 1990-04-09 Production of amino acids by methylotrophic bacillus

Country Status (9)

Country Link
EP (1) EP0422187B1 (en)
JP (1) JPH03505284A (en)
AT (1) ATE128187T1 (en)
AU (1) AU631640B2 (en)
BR (1) BR9006409A (en)
CA (1) CA2030529C (en)
DE (1) DE69022522T2 (en)
ES (1) ES2080825T3 (en)
WO (1) WO1990012105A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9100618A (en) * 1990-02-15 1991-10-29 Ajinomoto Kk PROCESS FOR COMPETENT FERMENTATION OF A BASIC L-AMINO-ACID AND AN ACID L-AMINO-ACID
KR0130196B1 (en) * 1990-02-15 1998-04-03 도바 다다스 Method for concurrent fermentation of basic amino acid and acidi amino acid
JP3046332B2 (en) * 1990-08-02 2000-05-29 協和醗酵工業株式会社 Production of amino acids by fermentation
AU9805698A (en) * 1997-10-17 1999-05-10 Regents Of The University Of Minnesota Production of glutamate using salt tolerant, methanol utilizing (bacillus)
US6083728A (en) * 1997-10-17 2000-07-04 Regents Of The University Of Minnesota Production of glutamate using wild type Bacillus methanolicus
KR20010031152A (en) * 1997-10-17 2001-04-16 리전츠 오브 더 유니버스티 오브 미네소타 Production of lysine using salt tolerant, methanol utilizing Bacillus
EP1063288A3 (en) * 1999-06-15 2001-01-17 Ajinomoto Co., Inc. Method for producing L-lysine
US6689601B2 (en) 2000-09-01 2004-02-10 E. I. Du Pont De Nemours And Company High growth methanotropic bacterial strain
JP2004166595A (en) 2002-11-20 2004-06-17 Ajinomoto Co Inc Method for producing l-amino acid by using methylotroph
JP2004166592A (en) 2002-11-20 2004-06-17 Ajinomoto Co Inc Method for producing l-amino acid using methylotroph
JP4120364B2 (en) 2002-11-20 2008-07-16 味の素株式会社 Method for producing L-lysine or L-arginine using methanol-assimilating bacteria
DE102004001674B4 (en) 2003-01-29 2019-01-24 Ajinomoto Co., Inc. Process for the preparation of L-lysine using methanol-utilizing bacteria
JP2009089603A (en) 2006-02-02 2009-04-30 Ajinomoto Co Inc Method for producing l-lysine using methanol-assimilating bacterium
JP2009153382A (en) 2006-03-30 2009-07-16 Ajinomoto Co Inc Method for producing carboxylic acid using methanol-assimilating bacterium
JP2011067095A (en) * 2008-01-10 2011-04-07 Ajinomoto Co Inc Method for producing target substance by fermentation process
GB201201178D0 (en) * 2012-01-25 2012-03-07 Sinvent As Novel enzymes
CN113331211A (en) * 2021-06-04 2021-09-03 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） Medicament for preventing and treating passion fruit stem basal rot and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1579160A (en) * 1967-08-05 1969-08-22
EP0218130A1 (en) * 1985-09-18 1987-04-15 Forschungszentrum Jülich Gmbh Process for the fermentative production of L-aminoacids from alpha-ketoacids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1579160A (en) * 1967-08-05 1969-08-22
EP0218130A1 (en) * 1985-09-18 1987-04-15 Forschungszentrum Jülich Gmbh Process for the fermentative production of L-aminoacids from alpha-ketoacids

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Abstracts of the Annual Meeting of the American Society for Microbiology, Miami Beach, Fla., 8-13 May 1988, (Washington, DC, US), M. GUETTLER et al.: "Characterization of a Methanol Oxidizing Thermophilic Member of the Genus Bacillus", see page 196, Abstract I-95 *
Abstracts of the Annual Meeting of the American Society for Microbiology, New Orleans, La., 14-18 May 1989, (Washinton, DC, US), F.J. SCHENDEL et al.: "L-Lysine Production from Methanol at High Cell Densities of MGA3, a Thermophilic Bacillus", see page 316, Abstract 0-69 *
Applied and Environmental Microbiology, Vol. 56, No. 4, April 1990, American Society for Microbiology, (Washington, DC, US), F.J. SCHENDEL et al.: "L-Lysine Production at 50üC by Mutants of a Newly Isolated and Characterized Methylotrophic Bacillus sp.", pages 963-970 *

Also Published As

Publication number Publication date
AU631640B2 (en) 1992-12-03
CA2030529A1 (en) 1990-10-11
WO1990012105A2 (en) 1990-10-18
ATE128187T1 (en) 1995-10-15
EP0422187B1 (en) 1995-09-20
DE69022522D1 (en) 1995-10-26
BR9006409A (en) 1991-08-06
ES2080825T3 (en) 1996-02-16
CA2030529C (en) 1999-10-19
EP0422187A1 (en) 1991-04-17
AU5522990A (en) 1990-11-05
DE69022522T2 (en) 1996-05-15
JPH03505284A (en) 1991-11-21

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