WO1990011051A1 - Apparatus for comminuting concretions in the body of a patient - Google Patents
Apparatus for comminuting concretions in the body of a patient Download PDFInfo
- Publication number
- WO1990011051A1 WO1990011051A1 PCT/SE1990/000181 SE9000181W WO9011051A1 WO 1990011051 A1 WO1990011051 A1 WO 1990011051A1 SE 9000181 W SE9000181 W SE 9000181W WO 9011051 A1 WO9011051 A1 WO 9011051A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- reflector
- spark gap
- patient
- ellipsoid
- circuit
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G10—MUSICAL INSTRUMENTS; ACOUSTICS
- G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
- G10K15/00—Acoustics not otherwise provided for
- G10K15/04—Sound-producing devices
- G10K15/06—Sound-producing devices using electric discharge
-
- G—PHYSICS
- G10—MUSICAL INSTRUMENTS; ACOUSTICS
- G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
- G10K11/00—Methods or devices for transmitting, conducting or directing sound in general; Methods or devices for protecting against, or for damping, noise or other acoustic waves in general
- G10K11/18—Methods or devices for transmitting, conducting or directing sound
- G10K11/26—Sound-focusing or directing, e.g. scanning
- G10K11/28—Sound-focusing or directing, e.g. scanning using reflection, e.g. parabolic reflectors
Definitions
- the present invention relates to apparatus for comminuting concretions in the body of a patient, and includes a liquid-filled focusing chamber with a reflector having an inner wall in the form of an open revolution ellipsoid, and closed by a bellows at its open end, said bellows intended to be placed against the patient's body, there being a spark gap arranged at the one focus of the ellipsoidal reflector for generating as shock wave intended for being focused at the other focal area of the revolution ellipsoid.
- Such an apparatus is previously known, e.g. from DE, Al, 3220751.
- this type of apparatus it is important to achieve good comminuting effect on the concretions or calculi (kidney or gall stones), simultaneously as the pain caused to the patient is sufficiently low for anesthetics not being required and it can be sufficient with analgesia and optional local anesthesia, e.g. EMLA cream (xylocain) on the skin where the wave inpinges. In this way the cost of anethetists is eliminated.
- the effective frequency for adequate therapy is in the range 0.3-1 MHz.
- a wavelength of 3 mm at these sites.
- Disintegration in calculi is achieved in the range 1/4 - 1/2 ⁇ , i.e. fragments of the size 0.75 - 1.5 mm are obtained, these being desired sizes.
- calculi are not homogeneous, i.e. disintegration can occur to an important degree due to inherent weakness bands. Fragments with the given sizes can subsequently be passed without causing further trouble.
- Lower frequencies do not give satisfactory therapy, e.g. for 100 kHz there is magnitude of disintegration in the range of 0.75-1.5 cm, which gives fragments which are much too large.
- Such low frequencies are not focused particularly well in the present size of the reflector and will thus pass into the body as a fairly badly focused wave. They involve large movements, however, like wip lashes, causing pain to the patient and by sudden jerks in the heart area they cause the risk of cardiac arhythmia of different kinds, such as auricular fibrillation and flutter.
- the simplest way to achieve such an effect is to form the reflector with a constant wall thickness equal to half the wavelength of the predetermined frequency, so that this frequency will be attenuated by half wave resonance less than other frequencies, and thus act with the greatest effect on the concretion.
- the wall thickness of the ellipsoidal reflector varies with the angle of incidence and refractive index applicable for the shock wave from the spark gap placed in the first focus, so that the wall thickness passed through along each ray path attains half a wavelength ( ⁇ /2). An amplified resonance phenomenon is thus achieved.
- a parallel resonance circuit for the spark being connected across the spark gap, this circuit forming a high-ohmic load for the desired, predetermined frequency and short- circuiting other frequencies.
- a parallel resonance circuit is suitably realized by a so-called quarter wave coaxial cable with the cable impedance selected equal to that of the spark.
- the ellipsoid is made with an aperture sufficiently large for the shock wave entry cone into the patient to be given a blunt cone angle.
- shock waves are generated by hydroacoustical discharges using the spark gap, the shock wave front reaching its maximum value within a time of the order of magnitude of l us (corresponding to the frequency MHz).
- the inductance in the discharge circuit feeding the spark gap must be low.
- the conductivity and refractive index are carefully adjusted in the liquid serving as a connection medium by the addition of salt and/or copper sulphate. This is essential for achieving the desired time derivative of the shock wave front and thus enabling generation of the desired frequency.
- the pressure in the second focal area, and therewith the disintegrating effect also vary considerably with conductivity.
- Figure 2 illustrates a discharge circuit for the spark gap in Figure 1
- FIG 3 a coaxial implementation of the discharge circuit.
- the focusing chamber is defined by an open ellipsoid 2 of revolution serving as a reflector, this reflector suitably being manufactured from acid-resistant stainless steel, and closed at its open end by a cylindrical bellows 4 with a rubber diaphragm 6 intended for placing against the patient's body during treatment.
- spark gap 8 which is fed from an electric circuit 10, and this gap is formed by two opposing electrodes 12, 14.
- Waves caused by spark discharge are transmitted from the focus F j and are reflected against the ellipsoid inside of the reflector 2 to the second focus of the ellipsoid, the focus ⁇ being situated in a concretion.
- a part of the energy transmitted from F j will, however, penetrate through the inner surface of the reflector 2 and reach its outer surface where it is reflected.
- the wall thickness in the reflector is adjusted so that for a given desired frequency there will be resonance in the focus F2 between the waves reflected against the inside and the outside of the reflector. This is most simply realized by making the ellipsoid reflector 2 with a constant thickness of half the wavelength for the desired frequency, so that this frequency is amplified in relation to surrounding frequencies by half-wave resonance, see Figure. 1.
- This resonance action can be amplified further by the reflector being made in such a way, with varying wall thickness, that the wall thickness along each ray path achieves half a wavelength, signifying that the wall thickness must vary as a function of the angle of incidence of the wave from the spark gap, while also taking into account the refractive index of the different materials.
- a parallel resonance circuit can be arranged across the spark gap, such as to form a high- ohmic load for the desired predetermined frequency and for short- circuiting other frequencies. This is suitably achieved by first deciding the impedance of the spark by measuring current and voltage at its discharge, and then connecting a so-called quarter wave coaxial cable having the same impedance as the spark.
- FIG. 2 there is illustrated an electric circuit for the apparatus in accordance with the invention.
- the schematically illustrated spark gap 8 disposed inside the reflector is fed from a capacitor C via a trigger means 18, suitably of the type with a moving auxiliary electrode 20, which is described in the patent application 8900995-5, filed concurrently with this application.
- the capacitor C in its turn is charged from a high voltage source 24 across a resistor R.
- a parallel resonance circuit Lj Cj is connected across the gap and dimensioned to form a high-ohmic load at the desired frequency, while it substantially short-circuits other frequencies.
- the parallel resonance circuit is suitably realized, as already mentioned, by using a quarter wave coaxial cable, i.e. a coaxial cable of a length equal to a quarter of a wavelength and short-circuited at the earthing end.
- a quarter wave coaxial cable i.e. a coaxial cable of a length equal to a quarter of a wavelength and short-circuited at the earthing end.
- a cable behaves as a parallel resonance circuit.
- the length will be of the order of 50 m.
- a shock wave with a sufficiently steep front must be generated to obtain the desired frequencies in the range 0.3-1 MHz.
- the front rising time should be of the order of magnitude 1 ms, corresponding to the frequency of 1 MHz.
- the coaxial implementation includes, as illustrated in Figure 3, the entire circuit including electrodes 12, 14, trigger circuit 18 and capacitor C and also provides a "transformer effect" which reduces self-induction.
- connection medium 16 The conductivity of the connection medium 16 is also of importance for achieving a sufficiently steep shock wave front, see Figure 1.
- the connection medium normally consists of de-gased water to which salt and/or copper sulphate has been added for adjusting conductivity and refractive index. De-gasing of the water is also affected by these additives. The additives result in a desired increased conductivity, and in addition it is attempted to ensure that the refractive index will be substantially the same as in human tissue. By not only adding salt but also copper sulphate corrosion problems are reduced, which is important when solely using a salt solution. Algae growth is also inhibited.
- connection medium 16 Water which has been carefully de-gased is utilized as connection medium 16, for avoiding cavitation which leads to so-called "acoustic opality". This is required in order for a well-defined focus to be achieved, i.e. lower energy can be used for achieving a given comminuting effect.
- de-gasing takes place by boiling at 50°C in a special vessel at a subpressure of -0.85 bar.
- the reflector is made with as large an aperture as possible.
- the reflector aperture may attain (180 mm) 230 mm, there being then obtained for the shock wave an input cone towards the patient with an angle ⁇ of about 80-90°, see Figure 1.
- the upper limit for this angle is determined by the limitation of the body's physical extension.
- the spark gap 12, 14 is fed from a capacitor C, see Figures 2 and 3, and the voltage is variable up to 30 kV.
- the circuit also includes a trigger means, schematically illustrated at 18, which is adapted for triggering the spark discharge with the aid of the R peak from an EKG signal.
- the distance between the reflector edge and focal point F£ is 13 cm, which is sufficient for most applications.
- the electrodes are of the re-usable type with individually exchangeable tips, and are made such that input current passes in a conductor around which the return current passes in a surrounding conductor, whereby resultant magnetic fields will counteract each other.
- Discharges can take place with a maximum interval of about 300 ms.
- the inventive apparatus is usable for comminuting kidney and gall stones.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO91913531A NO913531L (no) | 1989-03-21 | 1991-09-09 | Apparat til aa knuse konkrement. |
FI914393A FI914393A0 (fi) | 1989-03-21 | 1991-09-18 | Anordning foer soenderdelning av konkrement i kroppen pao en patient. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8900994-8 | 1989-03-21 | ||
SE8900994A SE465552B (sv) | 1989-03-21 | 1989-03-21 | Anordning foer soenderdelning av konkrement i kroppen paa en patient |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1990011051A1 true WO1990011051A1 (en) | 1990-10-04 |
Family
ID=20375412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE1990/000181 WO1990011051A1 (en) | 1989-03-21 | 1990-03-21 | Apparatus for comminuting concretions in the body of a patient |
Country Status (6)
Country | Link |
---|---|
US (1) | US5259368A (sv) |
EP (1) | EP0464130A1 (sv) |
JP (1) | JPH04504214A (sv) |
FI (1) | FI914393A0 (sv) |
SE (1) | SE465552B (sv) |
WO (1) | WO1990011051A1 (sv) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2304604A (en) * | 1995-09-01 | 1997-03-26 | Tzn Forschung & Entwicklung | Shock wave generator |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7189209B1 (en) | 1996-03-29 | 2007-03-13 | Sanuwave, Inc. | Method for using acoustic shock waves in the treatment of a diabetic foot ulcer or a pressure sore |
US6370419B2 (en) * | 1998-02-20 | 2002-04-09 | University Of Florida | Method and apparatus for triggering an event at a desired point in the breathing cycle |
US6702735B2 (en) | 2000-10-17 | 2004-03-09 | Charlotte Margaret Kelly | Device for movement along a passage |
CA2354462C (en) * | 2001-07-30 | 2008-09-23 | William K. Reilly | Medical line stabilizer |
DE10301875B4 (de) * | 2003-01-17 | 2004-11-18 | Sws Shock Wave Systems Ag | Vorrichtung zur Erzeugung von unterschiedlichen akustischen Druckwellen durch variable Reflexionsflächen |
US8328810B2 (en) * | 2004-06-17 | 2012-12-11 | Boston Scientific Scimed, Inc. | Slidable sheaths for tissue removal devices |
JP4896534B2 (ja) * | 2006-01-31 | 2012-03-14 | シスメックス株式会社 | 粒子分析装置用シース液 |
EP2525727A4 (en) | 2010-01-19 | 2017-05-03 | The Board of Regents of The University of Texas System | Apparatuses and systems for generating high-frequency shockwaves, and methods of use |
AR087170A1 (es) | 2011-07-15 | 2014-02-26 | Univ Texas | Aparato para generar ondas de choque terapeuticas y sus aplicaciones |
US20130340530A1 (en) * | 2012-06-20 | 2013-12-26 | General Electric Company | Ultrasonic testing device with conical array |
US10835767B2 (en) * | 2013-03-08 | 2020-11-17 | Board Of Regents, The University Of Texas System | Rapid pulse electrohydraulic (EH) shockwave generator apparatus and methods for medical and cosmetic treatments |
CA2985811A1 (en) | 2015-05-12 | 2016-11-17 | Soliton, Inc. | Methods of treating cellulite and subcutaneous adipose tissue |
TWI742110B (zh) * | 2016-07-21 | 2021-10-11 | 美商席利通公司 | 具備改良電極壽命之快速脈波電動液壓脈衝產生裝置及使用該裝置生成壓縮聲波之方法 |
EP3582686A4 (en) | 2017-02-19 | 2020-12-02 | Soliton, Inc. | LASER-INDUCED SELECTIVE OPTICAL RUPTURE IN A BIOLOGICAL ENVIRONMENT |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3150430C1 (de) * | 1981-12-19 | 1983-07-28 | Dornier System Gmbh, 7990 Friedrichshafen | "Schaltung zur Erzeugung einer Unterwasserentladung" |
DE2913251C2 (de) * | 1979-04-03 | 1985-08-01 | Richard Wolf Gmbh, 7134 Knittlingen | Vorrichtung zur berührungsfreien Zertrümmerung von Steinen in Körperhöhlen |
US4570634A (en) * | 1982-11-06 | 1986-02-18 | Dornier System Gmbh | Shockwave reflector |
US4630607A (en) * | 1983-07-19 | 1986-12-23 | N.V. Optische Industrie "De Oude Delft" | Apparatus for the non-contact disintegration of stony objects present in a body by means of sound shockwaves |
DE3543881C1 (de) * | 1985-12-12 | 1987-03-26 | Dornier Medizintechnik | Unterwasser-Elektrode fuer die beruehrungsfreie Lithotripsie |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4004266A (en) * | 1975-12-05 | 1977-01-18 | The United States Of America As Represented By The Secretary Of The Navy | Transducer array having low cross-coupling |
DE3319871A1 (de) * | 1983-06-01 | 1984-12-06 | Richard Wolf Gmbh, 7134 Knittlingen | Piezoelektrischer wandler zur zerstoerung von konkrementen im koerperinnern |
EP0196353A3 (de) * | 1985-04-04 | 1987-02-04 | DORNIER SYSTEM GmbH | Vorrichtung zur Vermeidung oder Minderung von Schmerzen bei der extracorporalen Lithotripsie |
US5095891A (en) * | 1986-07-10 | 1992-03-17 | Siemens Aktiengesellschaft | Connecting cable for use with a pulse generator and a shock wave generator |
FR2649252B1 (fr) * | 1989-06-30 | 1993-01-15 | Technomed Int Sa | Procede et dispositif de decharge d'un arc electrique dans un liquide electriquement conducteur et application au lithotrypteur |
DE3932959C1 (sv) * | 1989-10-03 | 1991-04-11 | Richard Wolf Gmbh, 7134 Knittlingen, De |
-
1989
- 1989-03-21 SE SE8900994A patent/SE465552B/sv not_active IP Right Cessation
-
1990
- 1990-03-21 EP EP90905726A patent/EP0464130A1/en not_active Withdrawn
- 1990-03-21 WO PCT/SE1990/000181 patent/WO1990011051A1/en not_active Application Discontinuation
- 1990-03-21 US US07/761,808 patent/US5259368A/en not_active Expired - Fee Related
- 1990-03-21 JP JP2505387A patent/JPH04504214A/ja active Pending
-
1991
- 1991-09-18 FI FI914393A patent/FI914393A0/fi not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2913251C2 (de) * | 1979-04-03 | 1985-08-01 | Richard Wolf Gmbh, 7134 Knittlingen | Vorrichtung zur berührungsfreien Zertrümmerung von Steinen in Körperhöhlen |
DE3150430C1 (de) * | 1981-12-19 | 1983-07-28 | Dornier System Gmbh, 7990 Friedrichshafen | "Schaltung zur Erzeugung einer Unterwasserentladung" |
US4570634A (en) * | 1982-11-06 | 1986-02-18 | Dornier System Gmbh | Shockwave reflector |
US4630607A (en) * | 1983-07-19 | 1986-12-23 | N.V. Optische Industrie "De Oude Delft" | Apparatus for the non-contact disintegration of stony objects present in a body by means of sound shockwaves |
DE3543881C1 (de) * | 1985-12-12 | 1987-03-26 | Dornier Medizintechnik | Unterwasser-Elektrode fuer die beruehrungsfreie Lithotripsie |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2304604A (en) * | 1995-09-01 | 1997-03-26 | Tzn Forschung & Entwicklung | Shock wave generator |
US5748563A (en) * | 1995-09-01 | 1998-05-05 | Tzn Forschungs- Und Entwicklungszentrum Unterluss Gmbh | Energy converter for generating high-power pulses |
GB2304604B (en) * | 1995-09-01 | 1999-11-10 | Tzn Forschung & Entwicklung | Generating high-intensity energy pulses |
Also Published As
Publication number | Publication date |
---|---|
SE8900994L (sv) | 1990-09-22 |
JPH04504214A (ja) | 1992-07-30 |
FI914393A0 (fi) | 1991-09-18 |
EP0464130A1 (en) | 1992-01-08 |
SE465552B (sv) | 1991-09-30 |
SE8900994D0 (sv) | 1989-03-21 |
US5259368A (en) | 1993-11-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5259368A (en) | Apparatus for comminuting concretions in the body of a patient | |
US8298162B2 (en) | Skin and adipose tissue treatment by nonfocalized opposing side shock waves | |
US4441486A (en) | Hyperthermia system | |
US3990452A (en) | Medical machine for performing surgery and treating using ultrasonic energy | |
DE3319871C2 (sv) | ||
US3329148A (en) | Control of electrotherapeutic apparatus | |
EP0590177B1 (de) | Gerät zum Erzeugen von Stosswellen für die berührungsfreie Zerstörung von Konkrementen in Körpern von Lebewesen | |
US6589191B2 (en) | Manually actuable ultrasonic disintegrator for breaking up or removing human or animal tissue | |
US4662375A (en) | Alleviating pain during extracoporal lithotripsy | |
EP0167670B1 (de) | Einrichtung zum Zertrümmern von im Körper eines Lebewesens befindlichen Konkrementen | |
US5109338A (en) | High-voltage generator and method for generating a high current, high-voltage pulse by pulse shaping for driving a shock wave source | |
US4793329A (en) | Shock wave source | |
US4920955A (en) | Shock wave source | |
Vergunst et al. | Assessment of shockwave pressure profiles in vitro: clinical implications | |
RU2151559C1 (ru) | Устройство для стимуляции метаболизма тканей ударно-волновыми импульсами | |
US5233980A (en) | Apparatus and method for generating shockwaves for the destruction of targets, particularly in extracorporeal lithotripsy | |
RU1804315C (ru) | Устройство дл локального разрушающего воздействи на структуру биообъекта | |
US20210353320A1 (en) | Reflector for Acoustic Pressure Wave Head | |
Štuka et al. | Nonlinear transmission of focused shock waves in nondegassed water | |
Jossinet et al. | Impedance changes in liver tissue exposed in vitro to high-energy ultrasound | |
SU1114409A1 (ru) | Устройство дл разрушени мочевых и желчных камней в организме человека | |
RU2155543C2 (ru) | Генератор ударно-волновых импульсов для дробления конкрементов | |
WO1990010419A1 (de) | Vorrichtung zur erzeugung von fokussierten akustischen wellenfeldern | |
JP3189293B2 (ja) | 超音波治療装置 | |
Baker et al. | The effect of receiver size on nonlinear pressure field measurements |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): DK FI JP NO US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB IT LU NL SE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1990905726 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 914393 Country of ref document: FI |
|
WWP | Wipo information: published in national office |
Ref document number: 1990905726 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1990905726 Country of ref document: EP |