WO1990006121A8 - Method for improving reproductive functions in mammals - Google Patents

Method for improving reproductive functions in mammals

Info

Publication number
WO1990006121A8
WO1990006121A8 PCT/US1989/005524 US8905524W WO9006121A8 WO 1990006121 A8 WO1990006121 A8 WO 1990006121A8 US 8905524 W US8905524 W US 8905524W WO 9006121 A8 WO9006121 A8 WO 9006121A8
Authority
WO
WIPO (PCT)
Prior art keywords
mammals
reproductive functions
vitamin
improving reproductive
improving
Prior art date
Application number
PCT/US1989/005524
Other languages
French (fr)
Other versions
WO1990006121A2 (en
Inventor
Hector F Deluca
Gary G Kwiecinski
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Priority to EP90901335A priority Critical patent/EP0401357B1/en
Priority to DE68926041T priority patent/DE68926041T2/en
Publication of WO1990006121A2 publication Critical patent/WO1990006121A2/en
Priority to DK188590A priority patent/DK188590A/en
Publication of WO1990006121A8 publication Critical patent/WO1990006121A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Magnetic Heads (AREA)
  • Lubrication Of Internal Combustion Engines (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A method of improving the fertility and reproductive capacity of male and female mammals by administering an amount of a vitamin D compound, such as vitamin D3, its active form 1,25-dihydroxyvitamin D3 or other compounds exhibiting vitamin D-like activity, to the mammal.
PCT/US1989/005524 1988-12-09 1989-12-06 Method for improving reproductive functions in mammals WO1990006121A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP90901335A EP0401357B1 (en) 1988-12-09 1989-12-06 Improving reproductive functions in mammals
DE68926041T DE68926041T2 (en) 1988-12-09 1989-12-06 IMPROVING REPRODUCTIVE FUNCTIONS IN MAMMALS
DK188590A DK188590A (en) 1988-12-09 1990-08-07 IMPROVING CAPACITY OF REPRODUCTION

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US281,993 1988-12-09
US07/281,993 US4970203A (en) 1988-12-09 1988-12-09 Method for improving reproductive functions in mammals

Publications (2)

Publication Number Publication Date
WO1990006121A2 WO1990006121A2 (en) 1990-06-14
WO1990006121A8 true WO1990006121A8 (en) 2005-06-16

Family

ID=23079641

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/005524 WO1990006121A2 (en) 1988-12-09 1989-12-06 Method for improving reproductive functions in mammals

Country Status (10)

Country Link
US (1) US4970203A (en)
EP (1) EP0401357B1 (en)
JP (1) JP2724913B2 (en)
AT (1) ATE135578T1 (en)
AU (1) AU624470B2 (en)
CA (1) CA1340653C (en)
DE (1) DE68926041T2 (en)
DK (1) DK188590A (en)
ES (1) ES2085345T3 (en)
WO (1) WO1990006121A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4220757A1 (en) * 1992-06-24 1994-01-05 Schering Ag Derivatives in the vitamin D series with modifications in the 20-position, process for their preparation, intermediates for this process, pharmaceutical preparations containing these derivatives and their use in the manufacture of medicaments
US5397776A (en) * 1993-08-20 1995-03-14 Wisconsin Alumni Research Foundation Vitamin D compounds with anti-progesterone activity
US5384313A (en) * 1993-11-24 1995-01-24 Wisconsin Alumni Research Foundation 21-norvitamin D compounds
US6043386A (en) * 1998-06-03 2000-03-28 John Hopkins University Non-calcemic, antiproliferative, transcriptionally active 24-fluorinated hybrid analogs of 1α,-25-dihydroxy vitamin D3
US20100227840A1 (en) * 2005-08-18 2010-09-09 Thau Kiong Chung Use of 25-hydroxy vitamin d3 to improve male animal fertility
ATE476104T1 (en) * 2005-11-25 2010-08-15 Dsm Ip Assets Bv USE OF 25-HYDROXY-VITAMIN D3 TO IMPROVE THE VITALITY OF ANIMALS
CN101336077B (en) * 2005-11-25 2013-08-14 帝斯曼知识产权资产管理有限公司 Use of 25-hydroxy vitamin D3 to improve vitality of animals
JP5165202B2 (en) * 2006-02-17 2013-03-21 中外製薬株式会社 Recovery system testicular model animal and male infertility treatment
JP2009532457A (en) * 2006-04-06 2009-09-10 ウイスコンシン アラムニ リサーチ ファンデーション 2-Methylene-1α-hydroxy-18,19,21-trinorvitamin D3 analogs and uses thereof
NZ570711A (en) 2006-04-06 2012-10-26 Wisconsin Alumni Res Found 2-Substituted-1alpha, 25-dihydroxy-19,26,27-trinor vitamin D analogs and uses thereof
WO2007118198A2 (en) * 2006-04-06 2007-10-18 Wisconsin Alumni Research Foundation 2-METHYLENE-1α,25-DIHYDROXY-19,21-DINORVITAMIN D3 ANALOGS AND USES THEREOF
US7704981B2 (en) * 2006-04-06 2010-04-27 Wisconsin Alumni Research Foundation 2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin D3 and uses thereof
MX2008012114A (en) * 2006-04-06 2009-03-06 Wisconsin Alumni Res Found 19-nor-vitamin d analogs with 1,2,or 3,2 heterocyclic ring.
JP2009532458A (en) * 2006-04-06 2009-09-10 ウイスコンシン アラムニ リサーチ ファンデーション 2-Methylene-1α-hydroxy-19,21-dinorvitamin D3 analog and use thereof
MX2008012674A (en) * 2006-04-10 2008-10-15 Wisconsin Alumni Res Found Lalpha-hydroxy-2- (3 ' -hydroxypropylidene) -19-n0r- vitamin d compounds with a 1,1-dimethylpropyl side chain.
RU2302874C1 (en) * 2006-06-22 2007-07-20 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Agent normalizing reproductive function in men and method for its preparing
AU2007306292A1 (en) * 2006-10-13 2008-04-17 Bioxell Spa Novel method of treatment of male sub-fertility
EP2358214B1 (en) * 2008-11-19 2013-10-02 DSM IP Assets B.V. Use of canthaxanthin and/or 25-oh d3 for improved hatchability in poultry
RU2487705C1 (en) * 2012-03-21 2013-07-20 ОКТАПАМ Лимитед Agent for improving reproductive function
RU2489142C1 (en) * 2012-03-21 2013-08-10 ОКТАПАМ Лимитед Agent for improving reproductive function
US20180271118A1 (en) * 2015-01-15 2018-09-27 Dsm Ip Assets B.V. Combination of 25-hydroxyvitamin d and antioxidants/anti-inflammatories for poultry ovarian health
RU2728709C1 (en) * 2019-12-25 2020-07-30 Марина Александровна Флорова Reproductive function enhancer

Also Published As

Publication number Publication date
JP2724913B2 (en) 1998-03-09
DE68926041D1 (en) 1996-04-25
AU624470B2 (en) 1992-06-11
WO1990006121A2 (en) 1990-06-14
DK188590D0 (en) 1990-08-07
CA1340653C (en) 1999-07-13
DK188590A (en) 1990-10-09
US4970203A (en) 1990-11-13
ES2085345T3 (en) 1996-06-01
JPH03502461A (en) 1991-06-06
ATE135578T1 (en) 1996-04-15
AU4841190A (en) 1990-06-26
DE68926041T2 (en) 1996-11-28
EP0401357A1 (en) 1990-12-12
EP0401357B1 (en) 1996-03-20

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