WO1990001168A3 - Automatic multiple-sample multiple-reagent chemical analyzer - Google Patents

Automatic multiple-sample multiple-reagent chemical analyzer Download PDF

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Publication number
WO1990001168A3
WO1990001168A3 PCT/US1989/003183 US8903183W WO9001168A3 WO 1990001168 A3 WO1990001168 A3 WO 1990001168A3 US 8903183 W US8903183 W US 8903183W WO 9001168 A3 WO9001168 A3 WO 9001168A3
Authority
WO
WIPO (PCT)
Prior art keywords
probe
analyzer
lamp
containers
test cells
Prior art date
Application number
PCT/US1989/003183
Other languages
French (fr)
Other versions
WO1990001168A2 (en
Inventor
Warren J Heath
Rene J Langer
Kermit W Jones
Charles A Bell
Original Assignee
Precision Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Precision Systems Inc filed Critical Precision Systems Inc
Priority to DE68915767T priority Critical patent/DE68915767D1/en
Priority to EP89908657A priority patent/EP0426729B1/en
Publication of WO1990001168A2 publication Critical patent/WO1990001168A2/en
Publication of WO1990001168A3 publication Critical patent/WO1990001168A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00425—Heating or cooling means associated with pipettes or the like, e.g. for supplying sample/reagent at given temperature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00435—Refrigerated reagent storage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00752—Type of codes bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
    • G01N2035/1086—Cylindrical, e.g. variable angle

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

An analyzer for chemical assays includes a turntable (20) which supports sample containers (22) and reagent containers (24) within a cooled volume and test cells (26) about the periphery of the cooled volume. A probe (30) is carried by a rotating arm (32) for withdrawing liquid from the containers and dispensing the liquid. Fixed stations are also provided in the path of the probe. One such station (40) serves to both wash the tip of the probe and to receive samples for flow-through analysis. Heaters (44, 46) associated with the probe and with the test cells increase the rate of reaction. Curved walls of test cell segments match the optics of an optical analyzer so that light from the analyzer lamp (124) is generally orthogonal to the curved surfaces. The light voltage of the lamp may be controlled as a function of lamp wavelength required for particular assays. The system provides multiple-point calibration and automatic dilution of samples.
PCT/US1989/003183 1988-07-25 1989-07-24 Automatic multiple-sample multiple-reagent chemical analyzer WO1990001168A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE68915767T DE68915767D1 (en) 1988-07-25 1989-07-24 SELF-ACTING, CHEMICAL MULTIPLE SAMPLE MULTIPLE REAGENT ANALYSIS ARRANGEMENT.
EP89908657A EP0426729B1 (en) 1988-07-25 1989-07-24 Automatic multiple-sample multiple-reagent chemical analyzer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22405988A 1988-07-25 1988-07-25
US224,059 1988-07-25

Publications (2)

Publication Number Publication Date
WO1990001168A2 WO1990001168A2 (en) 1990-02-08
WO1990001168A3 true WO1990001168A3 (en) 1990-05-03

Family

ID=22839136

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/003183 WO1990001168A2 (en) 1988-07-25 1989-07-24 Automatic multiple-sample multiple-reagent chemical analyzer

Country Status (4)

Country Link
EP (1) EP0426729B1 (en)
JP (1) JP3121603B2 (en)
DE (1) DE68915767D1 (en)
WO (1) WO1990001168A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132233A (en) * 1989-03-13 1992-07-21 Beckman Instruments, Inc. Sample injection cell
FR2672129B1 (en) * 1990-11-16 1994-04-08 Alcyon Analyser Sa MACHINE FOR PERFORMING ANALYZES OF A BIOLOGICAL MATERIAL FROM SAMPLES OF SAID MATERIAL AND REAGENT.
CH682463A5 (en) * 1991-12-12 1993-09-30 Hamilton Bonaduz Ag Method and device for cleaning pipette tips.
US5380487A (en) * 1992-05-05 1995-01-10 Pasteur Sanofi Diagnostics Device for automatic chemical analysis
US5972716A (en) * 1994-04-29 1999-10-26 The Perkin-Elmer Corporation Fluorescence monitoring device with textured optical tube and method for reducing background fluorescence
JP3063564B2 (en) * 1995-03-17 2000-07-12 株式会社日立製作所 Automatic analyzer
US6021253A (en) * 1997-06-12 2000-02-01 Beckman Coulter, Inc. Heating probe
JP3896447B2 (en) * 1997-06-12 2007-03-22 アークレイ株式会社 Clinical laboratory equipment
JP5255399B2 (en) * 2008-10-23 2013-08-07 古野電気株式会社 Rotating tray and biochemical automatic analyzer equipped with the same
CN102221620B (en) * 2010-04-14 2016-08-24 深圳迈瑞生物医疗电子股份有限公司 Quickly detect the system and method for test condition
KR101442066B1 (en) * 2012-11-27 2014-09-18 주식회사 엘지생명과학 Automatic in vitro diagnostic device comprising slanted rotary stirrer
CN107209115A (en) 2015-01-26 2017-09-26 百克特瑞欧扫描有限责任公司 Laser defusing measure instrument with rotating disc type fluidic sample device
JP6786149B2 (en) 2016-02-19 2020-11-18 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． Integrated transfer arm structure for analytical instruments
KR102074153B1 (en) * 2017-02-02 2020-02-06 바디텍메드(주) Automated Device for Analyzing Immunoassay in Liquid

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0041378A1 (en) * 1980-05-30 1981-12-09 Hitachi, Ltd. Automatic analytical instrument
GB2121169A (en) * 1982-05-26 1983-12-14 Orion Yhtymae Oy Analyser comprising a single apparatus for sample preparation and measurement
EP0152964A2 (en) * 1984-02-23 1985-08-28 F. Hoffmann-La Roche Ag Set of cuvettes
EP0217000A2 (en) * 1985-07-15 1987-04-08 Abbott Laboratories Reagent containment system for a clinical analyser

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0041378A1 (en) * 1980-05-30 1981-12-09 Hitachi, Ltd. Automatic analytical instrument
GB2121169A (en) * 1982-05-26 1983-12-14 Orion Yhtymae Oy Analyser comprising a single apparatus for sample preparation and measurement
EP0152964A2 (en) * 1984-02-23 1985-08-28 F. Hoffmann-La Roche Ag Set of cuvettes
EP0217000A2 (en) * 1985-07-15 1987-04-08 Abbott Laboratories Reagent containment system for a clinical analyser

Also Published As

Publication number Publication date
DE68915767D1 (en) 1994-07-07
EP0426729A1 (en) 1991-05-15
JP3121603B2 (en) 2001-01-09
JPH03506075A (en) 1991-12-26
EP0426729B1 (en) 1994-06-01
WO1990001168A2 (en) 1990-02-08

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