WO1989009815A1 - Nouveau virus de la famille vih-2 et ses procedes de detection - Google Patents

Nouveau virus de la famille vih-2 et ses procedes de detection Download PDF

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Publication number
WO1989009815A1
WO1989009815A1 PCT/US1989/001379 US8901379W WO8909815A1 WO 1989009815 A1 WO1989009815 A1 WO 1989009815A1 US 8901379 W US8901379 W US 8901379W WO 8909815 A1 WO8909815 A1 WO 8909815A1
Authority
WO
WIPO (PCT)
Prior art keywords
hiv
virus
antibodies
dna
antibody
Prior art date
Application number
PCT/US1989/001379
Other languages
English (en)
Inventor
George M. Shaw
Beatrice H. Hahn
Lilly I. Kong
Shei-Wen Lee
Original Assignee
Research Corporation Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corporation Technologies, Inc. filed Critical Research Corporation Technologies, Inc.
Publication of WO1989009815A1 publication Critical patent/WO1989009815A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

Nouveau virus de la famille des virus VIH-2. En particulier, rétrovirus antigéniquement plus similaire au VIH-1 qu'au VIH-2/ROD et VISMAC, bien que génétiquement distinct de celui-ci. Tout particulièrement, isolement et culture de VIH-2/ST, de façon à fournir une source dudit virus et de ses dérivés et leurs fragments, utiles pour développer des essais de dépistage dudit virus ou d'autres virus apparentés de la famille VIH-2. En outre, molécules d'ADN recombinant contenant le provirus VIH-2/ST dans son ensemble, ce qui permet d'obtenir une source de composants viraux recombinants utiles pour développer les essais de dépistage des virus VIH-2. Anticorps spécifiques des composants viraux et différents anticorps spécifiques des premiers anticorps, utiles pour développer des essais de dépistage des virus VIH-2. Procédé d'isolement de virus du type VIH-2/ST.
PCT/US1989/001379 1988-04-04 1989-04-04 Nouveau virus de la famille vih-2 et ses procedes de detection WO1989009815A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17756288A 1988-04-04 1988-04-04
US177,562 1988-04-04

Publications (1)

Publication Number Publication Date
WO1989009815A1 true WO1989009815A1 (fr) 1989-10-19

Family

ID=22649083

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/001379 WO1989009815A1 (fr) 1988-04-04 1989-04-04 Nouveau virus de la famille vih-2 et ses procedes de detection

Country Status (1)

Country Link
WO (1) WO1989009815A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0347365A2 (fr) * 1988-06-14 1989-12-20 QIAGEN GmbH Variants du virus HIV-2
WO1991019785A1 (fr) * 1990-06-15 1991-12-26 Innogenetics N.V. RETROVIRUS VIScpz-ant ET SES UTILISATIONS
EP0887427A2 (fr) * 1997-06-25 1998-12-30 Ortho-Clinical Diagnostics, Inc. Amplification et détection du HIV-1 et/or HIV-2

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987004459A1 (fr) * 1986-01-22 1987-07-30 Institut Pasteur Retrovirus du type hiv-2 susceptible de provoquer le sida, et ses constituants antigeniques et nucleiques
US4704357A (en) * 1985-09-30 1987-11-03 United States Of America As Represented By The Department Of Health And Human Services Immortalized T-lymphocyte cell line for testing HTLV-III inactivation
US4708818A (en) * 1983-09-15 1987-11-24 Institut Pasteur Human immunodeficiency viruses associated with Acquired Immune Deficiency Syndrome (AIDS), a diagnostic method for AIDS and pre-AIDS, and a kit therefor
US4716102A (en) * 1984-08-15 1987-12-29 Regents Of The University Of California Purified AIDS-associated virus ARV-2
US4759929A (en) * 1984-12-03 1988-07-26 Cabinet Harle & Phelip Novel treatment

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708818A (en) * 1983-09-15 1987-11-24 Institut Pasteur Human immunodeficiency viruses associated with Acquired Immune Deficiency Syndrome (AIDS), a diagnostic method for AIDS and pre-AIDS, and a kit therefor
US4716102A (en) * 1984-08-15 1987-12-29 Regents Of The University Of California Purified AIDS-associated virus ARV-2
US4759929A (en) * 1984-12-03 1988-07-26 Cabinet Harle & Phelip Novel treatment
US4704357A (en) * 1985-09-30 1987-11-03 United States Of America As Represented By The Department Of Health And Human Services Immortalized T-lymphocyte cell line for testing HTLV-III inactivation
WO1987004459A1 (fr) * 1986-01-22 1987-07-30 Institut Pasteur Retrovirus du type hiv-2 susceptible de provoquer le sida, et ses constituants antigeniques et nucleiques

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
J. MOL. BIOL., Volume 98, published 1975,. E. SOUTHERN: "Detection of Specific Sequences among DNA fragments separated by gel electrophoresis", pp. 503-517. See abstract, section(d) (pp. 506-508) and conslusion. *
NATURE, Volume 324, Number 18, published 25 December 1986, F. CLAVEL et al.: "Molecular cloning and polymorphism of the human immune deficiency virus type 2", pp. 691-695. See entire article. *
NATURE, Volume 326, published 16 April 1987, M. GUYADER et al.: "Genome organization and transactivation of the human immunodeficiency virus type 2", pp. 662-669. See entire article. *
NATURE, Volume 335, published 15 september 1988, X. YU et al.: "A naturally immunogenic virion-associated protein specific for HIV-2 and SIV", p. 262-265, see entire article. *
PROC. NATL. ACAD. SCI. USA, Volume 78, published November 1981, S. SUGGS et al.: "Use of synthetic oligonucleotides as hybridization probes: isolation of cloned DNA sequences for human beta-2-microglobulin", pp. 6613-6617, see entire article. *
PROC. NATL. ACAD. SCI. USA, Volume 85, published September 1988, A. MINASSIAN et al.: "Monoclonal antibodies against human immunodeficiency virus (HIV) type 2 core proteins: cross-reactivity with HIV type 1 and Simian immunodeficiency virus", pp. 6939-6943. See entire article. *
THE LANCET, Volume II (1987), published 7 November 1987, A. DALGLEISH et al.: "Neutralisation of HIV isolates by anti-idiotypic antibodies which mimic the T4 (CD4) epitope: a potential AIDS vaccine", pp. 1047-1049, see entire article. *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0347365A2 (fr) * 1988-06-14 1989-12-20 QIAGEN GmbH Variants du virus HIV-2
EP0347365A3 (fr) * 1988-06-14 1991-10-02 QIAGEN GmbH Variants du virus HIV-2
US5637455A (en) * 1988-06-14 1997-06-10 Qiagen Gmbh HIV-2 virus variants
US5677147A (en) * 1988-06-14 1997-10-14 Qiagen Gmbh HIV-2 virus variants
WO1991019785A1 (fr) * 1990-06-15 1991-12-26 Innogenetics N.V. RETROVIRUS VIScpz-ant ET SES UTILISATIONS
EP0494317A1 (fr) * 1990-06-15 1992-07-15 Innogenetics N.V. Le rétrovirus SIV cpz-ant et ses applications
EP0887427A2 (fr) * 1997-06-25 1998-12-30 Ortho-Clinical Diagnostics, Inc. Amplification et détection du HIV-1 et/or HIV-2
EP0887427A3 (fr) * 1997-06-25 2001-10-17 Ortho-Clinical Diagnostics, Inc. Amplification et détection du HIV-1 et/or HIV-2

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