WO1988008448A3 - Cell culture processes, materials and products - Google Patents

Cell culture processes, materials and products Download PDF

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Publication number
WO1988008448A3
WO1988008448A3 PCT/EP1988/000362 EP8800362W WO8808448A3 WO 1988008448 A3 WO1988008448 A3 WO 1988008448A3 EP 8800362 W EP8800362 W EP 8800362W WO 8808448 A3 WO8808448 A3 WO 8808448A3
Authority
WO
WIPO (PCT)
Prior art keywords
cells
instance
products
materials
cell culture
Prior art date
Application number
PCT/EP1988/000362
Other languages
French (fr)
Other versions
WO1988008448A2 (en
Inventor
Michael Bay
Original Assignee
Michael Bay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878709499A external-priority patent/GB8709499D0/en
Priority claimed from GB878711044A external-priority patent/GB8711044D0/en
Application filed by Michael Bay filed Critical Michael Bay
Publication of WO1988008448A2 publication Critical patent/WO1988008448A2/en
Publication of WO1988008448A3 publication Critical patent/WO1988008448A3/en
Priority to DK521989A priority Critical patent/DK521989A/en
Priority to FI894998A priority patent/FI894998A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Botany (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A new process for culturing anchorage dependent mammalian cells comprises growing the cells in the presence of an aqueous medium on the surface of a sheet of synthetic polymer gel that is swollen by the aqueous medium. The cells are for instance fibroblasts and/or epithelial cells. The polymer gel usually comprises a copolymer of hydroxyethylacrylate and hydroxyethyl methacrylate. The medium can contain growth factors, for instance epidermal and/or fibroblast growth factor. The product can be used as a wound dressing, especially for use as a skin replacement for instance in burn treatment.
PCT/EP1988/000362 1987-04-22 1988-04-21 Cell culture processes, materials and products WO1988008448A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK521989A DK521989A (en) 1987-04-22 1989-10-20 PROCEDURE FOR CULTIVATING CELLS AND MATERIALS FOR USE THEREOF
FI894998A FI894998A0 (en) 1987-04-22 1989-10-20 CELLODLINGSPROCESSER, MATERIAL OCH PRODUKTER.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8709499 1987-04-22
GB878709499A GB8709499D0 (en) 1987-04-22 1987-04-22 Cell culture processes
GB878711044A GB8711044D0 (en) 1987-05-11 1987-05-11 Cell culture
GB8711044 1987-05-11

Publications (2)

Publication Number Publication Date
WO1988008448A2 WO1988008448A2 (en) 1988-11-03
WO1988008448A3 true WO1988008448A3 (en) 1988-12-01

Family

ID=26292160

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1988/000362 WO1988008448A2 (en) 1987-04-22 1988-04-21 Cell culture processes, materials and products

Country Status (6)

Country Link
EP (1) EP0355112A1 (en)
JP (1) JPH02504221A (en)
AU (1) AU614747B2 (en)
DK (1) DK521989A (en)
FI (1) FI894998A0 (en)
WO (1) WO1988008448A2 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06104061B2 (en) * 1989-02-10 1994-12-21 花王株式会社 Cell culture support material
US5284766A (en) * 1989-02-10 1994-02-08 Kao Corporation Bed material for cell culture
EP0387975A1 (en) * 1989-03-16 1990-09-19 W.R. Grace & Co.-Conn. Cell culture substrate cell sheet, cell cluster and preparations thereof
AU621722B2 (en) * 1989-03-16 1992-03-19 W.R. Grace & Co.-Conn. Cell culture substrate, cell sheet, cell cluster and preparations thereof
US4996154A (en) * 1989-05-04 1991-02-26 Millipore Corporation Method for growing cellular tissue
GB9004911D0 (en) 1990-03-05 1990-05-02 Smith & Nephew Cell culture products
US5712137A (en) * 1990-03-05 1998-01-27 Smith & Nephew Plc Laminate of a culture substrate on a carrier for producing an apertured wound dressing
JPH0489000A (en) * 1990-05-02 1992-03-23 W R Grace & Co Cell cultivation kit and cell damage testing method
EP0470681A3 (en) * 1990-08-08 1992-04-22 W.R. Grace & Co.-Conn. Cell clusters or sheets comprising a plurality of cell species and preparations thereof
EP0552380A4 (en) * 1991-08-08 1995-01-25 Kao Corp Cell culture support, production thereof, and production of cell cluster using same
CZ281269B6 (en) * 1994-05-31 1996-07-17 Ústav Makromolekulární Chemie Av Čr Biologically active cover of extensive areas with and process for preparing thereof
EP0735135A3 (en) * 1995-03-31 1997-12-29 DIZG Deutsches Institüt für Zell- und Gewebeersatz gGmbH Cell sheets and transport system for cell sheets
GB9516556D0 (en) * 1995-08-12 1995-10-11 Smith & Nephew Cell culture laminate
EP0929661A4 (en) * 1995-11-15 2000-01-12 Univ Utah Novel method of culturing human epithelial cells for the identification of cancer therapeutics and diagnostics
US6596532B1 (en) 1997-12-12 2003-07-22 BIOMéRIEUX, INC. Device for isolation and surface culture of microorganisms from bulk fluids
AU4029399A (en) * 1998-06-10 1999-12-30 1. Lekarska Fakulta Univerzity Karlovy Polymer carrier for cultivation of keratinocytes
FR2807765B1 (en) * 2000-04-18 2004-12-31 Cell Culture Ct Comp PROCESS FOR CULTURING CELLS, CELL CLUSTERS OBTAINED BY SUCH PROCESSES AND USE THEREOF
US7358082B2 (en) * 2003-07-16 2008-04-15 Fujifilm Corporation Device and method for culturing cells
WO2009099539A2 (en) * 2008-01-30 2009-08-13 Corning Incorporated (meth)acrylate surfaces for cell culture, methods of making and using the surfaces
KR20110007600A (en) * 2008-01-30 2011-01-24 제론 코포레이션 Cell culture article and screening
EP2247718B1 (en) 2008-01-30 2019-01-16 Asterias Biotherapeutics, Inc. Synthetic surfaces for culturing stem cell derived cardiomyocytes
SG188096A1 (en) 2008-01-30 2013-03-28 Geron Corp Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
US8329469B2 (en) * 2008-01-30 2012-12-11 Geron Corporation Swellable (meth)acrylate surfaces for culturing cells in chemically defined media
TWI550088B (en) * 2014-01-16 2016-09-21 國立台灣大學 Method for rejuvenating aged cells and composition thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2094833A (en) * 1981-03-13 1982-09-22 Damon Corp Process and system for producing biological materials from encapsulated cells
FR2589165A1 (en) * 1985-10-24 1987-04-30 Inst Nat Sante Rech Med Process for producing a cultured human epithelium, the epithelial tissue obtained and its application in allografts

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2094833A (en) * 1981-03-13 1982-09-22 Damon Corp Process and system for producing biological materials from encapsulated cells
FR2589165A1 (en) * 1985-10-24 1987-04-30 Inst Nat Sante Rech Med Process for producing a cultured human epithelium, the epithelial tissue obtained and its application in allografts

Also Published As

Publication number Publication date
JPH02504221A (en) 1990-12-06
DK521989D0 (en) 1989-10-20
DK521989A (en) 1989-12-05
AU1685288A (en) 1988-12-02
FI894998A0 (en) 1989-10-20
AU614747B2 (en) 1991-09-12
EP0355112A1 (en) 1990-02-28
WO1988008448A2 (en) 1988-11-03

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