WO1987000034A2 - Bezoar artificiel - Google Patents

Bezoar artificiel Download PDF

Info

Publication number
WO1987000034A2
WO1987000034A2 PCT/GB1986/000392 GB8600392W WO8700034A2 WO 1987000034 A2 WO1987000034 A2 WO 1987000034A2 GB 8600392 W GB8600392 W GB 8600392W WO 8700034 A2 WO8700034 A2 WO 8700034A2
Authority
WO
WIPO (PCT)
Prior art keywords
balloon
overtube
stomach
supply line
valve
Prior art date
Application number
PCT/GB1986/000392
Other languages
English (en)
Inventor
Thomas Vincent Taylor
Original Assignee
Thomas Vincent Taylor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Vincent Taylor filed Critical Thomas Vincent Taylor
Publication of WO1987000034A2 publication Critical patent/WO1987000034A2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013—Implantable devices or invasive measures
    • A61F5/003—Implantable devices or invasive measures inflatable

Definitions

  • the present invention relates to artificial bezoars and to apparatus for treating obesity which includes an artificial bezoar.
  • a second problem is how to achieve oral insertion without damaging oesophageal tissue, and yet another problem is to achieve reliable inflation of a balloon after it has been introduced into the stomach cavity.
  • EP-0137878-A discloses apparatus which includes a stomach tube which contains an uninflated stomach balloon at a leading end of the stomach tube. This one end of the stomach tube is slit to the end of the tube, and the slit
  • apparatus for treating obesity in a patient comprising a valved balloon for placement in the stomach of the patient and a fluid supply line having a far end detachably connected to the valve and l& a near end for connection externally of the patient to a fluid supply means for inflation of the balloon within the stomach, the supply line and the balloon prior to its . inflation being accommodated within an overtube by which the balloon may be introduced orally into the stomach, the
  • 20uninflated balloon being housed adjacent a leading end of the overtube, characterised in that the leading end of. the overtube is closed and has a smoothly convex shape, and in that the cylindrical wall of the overtube adjacent said closed leading end includes an elongate fully-bounded
  • a flexible tube 30of a length in a range from 60 to 70 cms and a diameter in the range of from 1 to 1.5 cms similar to the tubes which are currently employed for gastric aspiration.
  • the tip of the overtube is smooth and the inflating balloon exits through a lengthwise sideways-facing slit-, so that the 35leading end of the overtube is easily introduced into the stomach and removed from it.
  • a standard Luer fitting for convenient attachment to a fluid source, which may be, for example, a syringe or an infusion line.
  • a fluid source which may be, for example, a syringe or an infusion line.
  • the leading i.e. distal end is tapered for insertion into a correspondingly shaped female element of the valve of the balloon for the purpose of inflation, and subsequent detachment by traction to leave the balloon free-floating in the stomach.
  • the balloon is of pear (piriform) or oval (ellipsoidal) shape and is of elastomeric material .
  • it is inflated through a self-sealing valve located at a narrow end of the balloon.
  • a balloon of ellipsoidal or piriform shape complies more easily with the natural pear shape of the human stomach than does a spherical balloon, and without producing undue dilation of the central stomach. Such dilation could produce abdominal discomfort around the widest .parts of the balloon and impair the process of gastric emptying.
  • the longitudinal axis of the balloon will tend to align with the longitudinal axis of the stomach, and the balloon will be .Tiore likely to occupy space in the more proximal stomach where the satiety centre is thought to lie.
  • a balloon of the preferred shape will furthermore leave less of the reservoir capacity of the stomach available for food storage and will have a greater flexibility for increased capacity without producing undue gastric distortion, stretching tension or mucosal damage.
  • the balloon should be adapted to contain about 500 millilitres of liquid under inflation in normal use, but preferably it should be able when required to accommodate liquid up to an amount of 1 litre or more.
  • the wall thickness should be as small as .possible for passage along the oesophagus whilst deflated but large enough to withstand the long-term, potentially damaging, effects of intragastric acid, food products and pressure effects of the vigorously contracting stomach.
  • the chosen wall thickness is the optimum compromise between these opposed requi rements .
  • the balloon valve should be competent and continent against fluid leakage over a relatively long period of time, that is, a period of months, say six months.
  • it is constructed of the same material as the balloon for ease of manufacture and it should add to the weight of the balloon as little as possible.
  • an artificial bezoar being a capsule adapted to be swallowed or otherwise delivered orally to the stomach the capsule comprising a resilient balloon arranged in a compact, deflated disposition and containing a substance which is capable of undergoing a change of volume of at least two decimal orders of magnitude to inflate the balloon in the stomach.
  • the substance is capable of undergoing such a change of volume is for it to undergo a chemical reaction which results in the evolution of gas.
  • the gas should be one which does not harm the human body.
  • Carbon dioxide is considered acceptable.
  • the capsule might contain a substance such as sodium bicarbonate which reacts with hydrochloric acid to generate gasesous carbon dioxide.
  • the acid could be introduced into the capsule by injection with a needle through a self-sealing wall area of the capsule, and the capsule swallowed immediately thereafter so that inflation of the balloon takes place in the stomach. Tube delivery to the stomach, instead of swallowing, would avoid possible blockage of the oesophagus as a result of premature balloon inflation.
  • the balloon from a material which is a semi -per eabl e membrane .
  • a material which is a semi -per eabl e membrane and to enclose within the balloon a small amount of a substance which has the capacity to absorb, in large quantity, the water or gastric fluid which passes inwardly into the balloon through the semi -permeabl e membrane wall .
  • certain cellulose materials have the necessary properties.
  • the balloon are packaged in a tight and compact disposition within a capsule which is adapted to be swallowed and is formed from a material which dissolves in the stomach to allow contact of the gastric fluids with the semi -permeabl e membrane balloon.
  • Figure 1 is a perspective view of a first embodiment of the invention
  • Figure 2 is a scrap section along the longitudinal axis of the valve of the balloon of Figure 1;
  • Figure 3 is a side view, partly in .section, of a capsule which is a second embodiment of the invention.
  • Figure 4 is view like Figure 3, of a third embodiment .
  • a balloon 10 of silicone rubber has a valve 11 which accommodates the distal end 12 of a liquid supply line 13 which extends the full length of an overtube 14 to a liquid supply syringe 15.
  • a liquid supply line 13 which extends the full length of an overtube 14 to a liquid supply syringe 15.
  • liquid may be delivered down the supply line to the balloon 10 to inflate it and cause it to exit the overtube 14 through an elongate, fully bounded aperture 17 in the cylindrical wall of the overtube 14 adjacent its distal end 16.
  • Figure 2 shows the construction of the valve 11.
  • a hollow stem 20 bonded to the wall of the balloon 10 has a closed end 21 but an aperture 22 in its cylindrical wall 23.
  • a sealing sleeve 24 overlies the aperture 22 and allows liquid to flow from inside the stem 20 to inside the cavity of the balloon 10 but not in the opposite direction.
  • the sleeve 24 could be a skirt around the stem 20 or a flap over the aperture 22.
  • valve 11 can be so designed that manual squeezing of it will allow fluid to escape through the valve.
  • the distal end 12 of the supply line 13 is a firm friction fit in the stem 20.
  • tension on the supply line 13 will bring the balloon up against either the overtube or the oesophageal sphincter, and further pulling of the supply line will draw the distal end thereof out of the hollow stem 20 of the valve 11 and allow the balloon to float freely within the stomach, if the supply line is made of resilient material , tension on it will tend to reduce its diameter. This effect should assist its disengagement from the stem 20 of the valve 13.
  • the capsule 30 of Figure 3 contains a tightly-packed balloon 31 with a neck 32 bonded to an open end 33 of a short length of tube 34.
  • the other end 35 of the tube 34 is closed by a self-sealing elasto eric plug 36 of a material which resists chemical attack by stomach acids but allows passage of a syringe needle and closes up after passage of the needle.
  • 500 ml of CO2 is generated by injecting 1 ml of N/10 Hydrochloric acid into 1 g of sodium bicarbonate. Inflation of the balloon 31 causes the capsule 30 to fall away.
  • the capsule is swallowed immediately after injection of the acid, and can be made of a material which gradually dissolves or is consumed in the stomach.
  • the balloon 40 is made of a material through which water may pass to a medium 41 within the balloon 40. which swells up on contact with the water.
  • a medium 41 is a cellulose material .
  • the balloon 40 is contained in a two-part capsule 42 which dissolves in the stomach or is consumed by it.

Landscapes

  • Health & Medical Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

Un ballon gonflable (10) est placé dans l'estomac, pour traiter l'obésité en réduisant l'appétit. Le ballon peut être gonflé par un liquide qui lui parvient par l'intermédiaire d'une conduite d'amenée (Fig. 1), par le produit de réaction gazeux d'une réaction chimique à l'intérieur du ballon (Fig. 3), ou par absorption de liquide à travers sa paroi semi-perméable (Fig. 4). Le ballon est de préférence piriforme ou ellipsoïdal. L'acheminement à l'estomac du ballon (10) et de la ligne d'amenée (13) par un sur-tube (14) présentant une extrémité lisse fermée (16) est réalisé en ménageant une fente latérale (17) totalement délimitée dans le sur-tube (14) par laquelle le ballon (10) sort du sur-tube lors de son gonflage. La valve (11) du ballon et la conduite d'amenée (13) sont de préférence à emboîtement mutuel par friction, permettant ainsi d'exercer une traction uniquement sur la conduite d'amenée pour laisser le ballon flotter librement dans l'estomac à la suite de son gonflage.
PCT/GB1986/000392 1985-07-05 1986-07-07 Bezoar artificiel WO1987000034A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8517092 1985-07-05
GB858517092A GB8517092D0 (en) 1985-07-05 1985-07-05 Artificial bezoar

Publications (1)

Publication Number Publication Date
WO1987000034A2 true WO1987000034A2 (fr) 1987-01-15

Family

ID=10581867

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1986/000392 WO1987000034A2 (fr) 1985-07-05 1986-07-07 Bezoar artificiel

Country Status (3)

Country Link
EP (1) EP0232301A1 (fr)
GB (1) GB8517092D0 (fr)
WO (1) WO1987000034A2 (fr)

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000376A1 (fr) * 1988-07-05 1990-01-25 Cantenys Jose Ballon intragastrique
WO2000067682A1 (fr) * 1999-05-06 2000-11-16 Lts Lohmann Therapie-Systeme Ag Forme d'administration permettant de reduire le volume gastrique
US6579301B1 (en) * 2000-11-17 2003-06-17 Syntheon, Llc Intragastric balloon device adapted to be repeatedly varied in volume without external assistance
WO2004084763A2 (fr) 2003-03-19 2004-10-07 Phagia Technology Dispositif occupant du volume intragastrique auto-gonflable
WO2005107641A2 (fr) 2004-05-03 2005-11-17 Fulfillium, Inc. Procede et systeme de commande du volume gastrique
WO2006055839A2 (fr) 2004-11-19 2006-05-26 Fulfillium, Inc. Detection de breche sans fil
US7066945B2 (en) 2001-05-17 2006-06-27 Wilson-Cook Medical Inc. Intragastric device for treating obesity
WO2007113714A1 (fr) * 2006-03-30 2007-10-11 Koninklijke Philips Electronics N.V. Pilule digestive extensible
US7500944B2 (en) 2003-06-27 2009-03-10 Ethicon Endo-Surgery, Inc. Implantable band with attachment mechanism
WO2009128882A1 (fr) * 2008-04-14 2009-10-22 Gore Enterprise Holdings, Inc. Dispositif occupant un volume intra-gastrique
US7951067B2 (en) 2003-06-27 2011-05-31 Ethicon Endo-Surgery, Inc. Implantable band having improved attachment mechanism
EP2356956A1 (fr) 2006-03-28 2011-08-17 Spatz-Fgia Inc. Ancrage gastro-intestinal flottant
WO2011136745A1 (fr) * 2010-04-30 2011-11-03 Nanyang Technological University Dispositif de gonflage de ballonnet et procédé afférent
US8095218B2 (en) 2005-07-13 2012-01-10 Betastim, Ltd. GI and pancreatic device for treating obesity and diabetes
US8162969B2 (en) 2008-10-16 2012-04-24 Obalon Therapeutics, Inc. Intragastric device
US8216268B2 (en) * 2005-12-22 2012-07-10 Cook Medical Technologies Llc Intragastric bag for treating obesity
WO2012097225A2 (fr) 2011-01-13 2012-07-19 Sensurtec, Inc. Détection de brèche dans des structures solides
WO2012099610A1 (fr) 2011-01-21 2012-07-26 Obalon Therapeutics, Inc. Dispositif intragastrique
US8292911B2 (en) 2011-01-21 2012-10-23 Obalon Therapeutics, Inc. Intragastric device
US8403952B2 (en) 2004-12-27 2013-03-26 Spatz-Fgia, Inc. Floating gastrointestinal anchor
US8647358B2 (en) 2011-01-21 2014-02-11 Obalon Therapeutics Inc. Intragastric device
US8740927B2 (en) 2011-01-21 2014-06-03 Obalon Therapeutics Inc. Intragastric device
US8992561B2 (en) 2011-01-21 2015-03-31 Obalon Therapeutics, Inc. Intragastric device
US9155528B2 (en) 2012-01-08 2015-10-13 Vibrynt, Inc. Methods, instruments and devices for extragastic reduction of stomach volume
US9314362B2 (en) 2012-01-08 2016-04-19 Vibrynt, Inc. Methods, instruments and devices for extragastric reduction of stomach volume
US9456915B2 (en) 2004-11-19 2016-10-04 Fulfilium, Inc. Methods, devices, and systems for obesity treatment
US9895248B2 (en) 2014-10-09 2018-02-20 Obalon Therapeutics, Inc. Ultrasonic systems and methods for locating and/or characterizing intragastric devices
US9974680B2 (en) 2004-12-27 2018-05-22 Spatz Fgia, Inc. System and methods for internalization of external components of adjustable intragastric balloon
US10264995B2 (en) 2013-12-04 2019-04-23 Obalon Therapeutics, Inc. Systems and methods for locating and/or characterizing intragastric devices
US10335303B2 (en) 2015-12-07 2019-07-02 Obalon Therapeutics, Inc. Intragastric device
US10350100B2 (en) 2016-04-12 2019-07-16 Obalon Therapeutics, Inc. System for detecting an intragastric balloon
US10537453B2 (en) 2015-12-16 2020-01-21 Obalon Therapeutics, Inc. Intragastric device with expandable portions
US10857019B2 (en) 2012-11-26 2020-12-08 Spatz Fgia, Inc. System and methods for internalization of external components of an adjustable intragastric balloon
US10893966B2 (en) 2017-02-09 2021-01-19 Spatz FGIA Ltd Check valve with docking station for gastrointestinal balloon
US11819433B2 (en) 2016-11-04 2023-11-21 Reshape Lifesciences Inc. Pressure control system for intragastric device

Cited By (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000376A1 (fr) * 1988-07-05 1990-01-25 Cantenys Jose Ballon intragastrique
US5129915A (en) * 1988-07-05 1992-07-14 Jose Cantenys Intragastric balloon
WO2000067682A1 (fr) * 1999-05-06 2000-11-16 Lts Lohmann Therapie-Systeme Ag Forme d'administration permettant de reduire le volume gastrique
US6579301B1 (en) * 2000-11-17 2003-06-17 Syntheon, Llc Intragastric balloon device adapted to be repeatedly varied in volume without external assistance
US7066945B2 (en) 2001-05-17 2006-06-27 Wilson-Cook Medical Inc. Intragastric device for treating obesity
EP1610737A2 (fr) * 2003-03-19 2006-01-04 Phagia Technology Dispositif occupant du volume intragastrique auto-gonflable
EP2204149A3 (fr) * 2003-03-19 2010-07-21 Obalon Therapeutics, Inc Dispositif d'occupation du volume intragastrique autogonflant
WO2004084763A2 (fr) 2003-03-19 2004-10-07 Phagia Technology Dispositif occupant du volume intragastrique auto-gonflable
EP1610737A4 (fr) * 2003-03-19 2008-04-02 Phagia Technology Dispositif occupant du volume intragastrique auto-gonflable
US7500944B2 (en) 2003-06-27 2009-03-10 Ethicon Endo-Surgery, Inc. Implantable band with attachment mechanism
US7951067B2 (en) 2003-06-27 2011-05-31 Ethicon Endo-Surgery, Inc. Implantable band having improved attachment mechanism
WO2005107641A2 (fr) 2004-05-03 2005-11-17 Fulfillium, Inc. Procede et systeme de commande du volume gastrique
US8066780B2 (en) 2004-05-03 2011-11-29 Fulfillium, Inc. Methods for gastric volume control
WO2006055839A2 (fr) 2004-11-19 2006-05-26 Fulfillium, Inc. Detection de breche sans fil
US9445930B2 (en) 2004-11-19 2016-09-20 Fulfillium, Inc. Methods, devices, and systems for obesity treatment
US9456915B2 (en) 2004-11-19 2016-10-04 Fulfilium, Inc. Methods, devices, and systems for obesity treatment
US11026825B2 (en) 2004-11-19 2021-06-08 Fulfillium, Inc. Methods, devices, and systems for obesity treatment
US9808367B2 (en) 2004-11-19 2017-11-07 Fulfillium, Inc. Methods, devices, and systems for obesity treatment
US8070807B2 (en) 2004-11-19 2011-12-06 Fulfillium, Inc. Wireless breach detection
US10179060B2 (en) 2004-11-19 2019-01-15 Fulfillium, Inc. Methods, devices, and systems for obesity treatment
US10524946B2 (en) 2004-11-19 2020-01-07 Fulfillium, Inc. Methods, devices, and systems for obesity treatment
US10285835B2 (en) 2004-11-19 2019-05-14 Fulfillium, Inc. Methods, devices, and systems for obesity treatment
US8403952B2 (en) 2004-12-27 2013-03-26 Spatz-Fgia, Inc. Floating gastrointestinal anchor
US9974680B2 (en) 2004-12-27 2018-05-22 Spatz Fgia, Inc. System and methods for internalization of external components of adjustable intragastric balloon
US8095218B2 (en) 2005-07-13 2012-01-10 Betastim, Ltd. GI and pancreatic device for treating obesity and diabetes
US8216268B2 (en) * 2005-12-22 2012-07-10 Cook Medical Technologies Llc Intragastric bag for treating obesity
AU2006330911B2 (en) * 2005-12-22 2012-10-04 Cook Medical Technologies Llc Intragastric bag for treating obesity
US8430894B2 (en) 2006-03-28 2013-04-30 Spatz-Fgia, Inc. Floating gastrointestinal anchor
EP2356956A1 (fr) 2006-03-28 2011-08-17 Spatz-Fgia Inc. Ancrage gastro-intestinal flottant
WO2007113714A1 (fr) * 2006-03-30 2007-10-11 Koninklijke Philips Electronics N.V. Pilule digestive extensible
WO2009128882A1 (fr) * 2008-04-14 2009-10-22 Gore Enterprise Holdings, Inc. Dispositif occupant un volume intra-gastrique
US10327936B2 (en) 2008-10-16 2019-06-25 Obalon Therapeutics, Inc. Intragastric device
US8845674B2 (en) 2008-10-16 2014-09-30 Obalon Therapeutics, Inc. Intragastric device
US10085865B2 (en) 2008-10-16 2018-10-02 Obalon Therapeutics, Inc. Intragastric volume-occupying device and method for fabricating same
US11219543B2 (en) 2008-10-16 2022-01-11 Reshape Lifesciences Inc. Intragastric device
US9539132B2 (en) 2008-10-16 2017-01-10 Obalon Therapeutics, Inc. Intragastric device
US9072583B2 (en) 2008-10-16 2015-07-07 Obalon Therapeutics, Inc. Intragastric volume-occupying device and method for fabricating same
US10874537B2 (en) 2008-10-16 2020-12-29 Obalon Therapeutics, Inc. Intragastric volume-occupying device and method for fabricating same
US10675165B2 (en) 2008-10-16 2020-06-09 Obalon Therapeutics, Inc. Intragastric volume-occupying device and method for fabricating same
US8162969B2 (en) 2008-10-16 2012-04-24 Obalon Therapeutics, Inc. Intragastric device
WO2011136745A1 (fr) * 2010-04-30 2011-11-03 Nanyang Technological University Dispositif de gonflage de ballonnet et procédé afférent
US9375554B2 (en) 2010-04-30 2016-06-28 National University Of Singapore Balloon inflating device and a method for inflating a balloon
WO2012097225A2 (fr) 2011-01-13 2012-07-19 Sensurtec, Inc. Détection de brèche dans des structures solides
US8963708B2 (en) 2011-01-13 2015-02-24 Sensurtec, Inc. Breach detection in solid structures
US9504576B2 (en) 2011-01-13 2016-11-29 Sensurtec, Inc. Breach detection in solid structures
US8740927B2 (en) 2011-01-21 2014-06-03 Obalon Therapeutics Inc. Intragastric device
US10463520B2 (en) 2011-01-21 2019-11-05 Obalon Therapeutics, Inc. Intragastric device
US8647358B2 (en) 2011-01-21 2014-02-11 Obalon Therapeutics Inc. Intragastric device
US9827128B2 (en) 2011-01-21 2017-11-28 Obalon Therapeutics, Inc. Intragastric device
US11974934B2 (en) 2011-01-21 2024-05-07 Reshape Lifesciences Inc. Intragastric device
EP2665511A1 (fr) * 2011-01-21 2013-11-27 Obalon Therapeutics, Inc. Dispositif intragastrique
US9468550B2 (en) 2011-01-21 2016-10-18 Obalon Therapeutics, Inc. Intragastric device
US8292911B2 (en) 2011-01-21 2012-10-23 Obalon Therapeutics, Inc. Intragastric device
US11779482B2 (en) 2011-01-21 2023-10-10 Reshape Lifesciences Inc. Intragastric device
WO2012099610A1 (fr) 2011-01-21 2012-07-26 Obalon Therapeutics, Inc. Dispositif intragastrique
EP2665511A4 (fr) * 2011-01-21 2014-06-11 Obalon Therapeutics Inc Dispositif intragastrique
US11737899B2 (en) 2011-01-21 2023-08-29 Reshape Lifesciences Inc. Intragastric device
US8992561B2 (en) 2011-01-21 2015-03-31 Obalon Therapeutics, Inc. Intragastric device
US9662239B2 (en) 2011-01-21 2017-05-30 Obalon Therapeutics, Inc. Intragastric device
US9351862B2 (en) 2011-01-21 2016-05-31 Obalon Therapeutics, Inc. Intragastric device
US9011477B2 (en) 2011-01-21 2015-04-21 Obalon Therapeutics, Inc. Intragastric device
US10610396B2 (en) 2011-01-21 2020-04-07 Obalon Therapeutics, Inc. Intragastric device
US10773061B2 (en) 2011-01-21 2020-09-15 Obalon Therapeutics, Inc. Intragastric device
US9314362B2 (en) 2012-01-08 2016-04-19 Vibrynt, Inc. Methods, instruments and devices for extragastric reduction of stomach volume
US9155528B2 (en) 2012-01-08 2015-10-13 Vibrynt, Inc. Methods, instruments and devices for extragastic reduction of stomach volume
US10857019B2 (en) 2012-11-26 2020-12-08 Spatz Fgia, Inc. System and methods for internalization of external components of an adjustable intragastric balloon
US10264995B2 (en) 2013-12-04 2019-04-23 Obalon Therapeutics, Inc. Systems and methods for locating and/or characterizing intragastric devices
US9895248B2 (en) 2014-10-09 2018-02-20 Obalon Therapeutics, Inc. Ultrasonic systems and methods for locating and/or characterizing intragastric devices
US10335303B2 (en) 2015-12-07 2019-07-02 Obalon Therapeutics, Inc. Intragastric device
US10537453B2 (en) 2015-12-16 2020-01-21 Obalon Therapeutics, Inc. Intragastric device with expandable portions
US10350100B2 (en) 2016-04-12 2019-07-16 Obalon Therapeutics, Inc. System for detecting an intragastric balloon
US11819433B2 (en) 2016-11-04 2023-11-21 Reshape Lifesciences Inc. Pressure control system for intragastric device
US10893966B2 (en) 2017-02-09 2021-01-19 Spatz FGIA Ltd Check valve with docking station for gastrointestinal balloon

Also Published As

Publication number Publication date
GB8517092D0 (en) 1985-08-14
EP0232301A1 (fr) 1987-08-19

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