WO1986003495A3 - Derives des substances p et de leurs fragments - Google Patents
Derives des substances p et de leurs fragments Download PDFInfo
- Publication number
- WO1986003495A3 WO1986003495A3 PCT/EP1985/000667 EP8500667W WO8603495A3 WO 1986003495 A3 WO1986003495 A3 WO 1986003495A3 EP 8500667 W EP8500667 W EP 8500667W WO 8603495 A3 WO8603495 A3 WO 8603495A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fragments
- derivatives
- substances
- ethoxy
- methoxy
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title 1
- QDZOEBFLNHCSSF-PFFBOGFISA-N (2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide Chemical class C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](N)CCCNC(N)=N)C1=CC=CC=C1 QDZOEBFLNHCSSF-PFFBOGFISA-N 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
- Details Of Aerials (AREA)
- Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE8686900104T DE3584288D1 (de) | 1984-12-11 | 1985-12-05 | Analoge der verbindung p. |
AT86900104T ATE68003T1 (de) | 1984-12-11 | 1985-12-05 | Analoge der verbindung p. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT23993/84A IT1177379B (it) | 1984-12-11 | 1984-12-11 | Derivati della sostanza p e di suoi frammenti |
IT23993A/84 | 1984-12-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1986003495A2 WO1986003495A2 (fr) | 1986-06-19 |
WO1986003495A3 true WO1986003495A3 (fr) | 1986-07-31 |
Family
ID=11211370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1985/000667 WO1986003495A2 (fr) | 1984-12-11 | 1985-12-05 | Derives des substances p et de leurs fragments |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0217804B1 (fr) |
JP (1) | JPS62501212A (fr) |
AT (1) | ATE68003T1 (fr) |
DE (1) | DE3584288D1 (fr) |
IT (1) | IT1177379B (fr) |
WO (1) | WO1986003495A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3815913A1 (de) * | 1988-05-10 | 1989-11-23 | Sandoz Ag | Neue reninhemmer, verfahren zu deren herstellung und deren verwendung |
US7235531B2 (en) | 1999-12-21 | 2007-06-26 | Takeda Pharmaceutical Company | Tachykinin-like polypeptides and use thereof |
CN102612373B (zh) * | 2009-11-11 | 2016-03-02 | 国立大学法人山口大学 | 消化器官疾病治疗剂 |
CN116925183A (zh) * | 2022-03-31 | 2023-10-24 | 中国医学科学院医药生物技术研究所 | 一类多肽化合物及其制备方法和应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4059693A (en) * | 1976-06-11 | 1977-11-22 | University Patents, Inc. | Analgesic action of substance P |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3862114A (en) * | 1971-11-22 | 1975-01-21 | Ici Australia Ltd | Analogs of substance p |
US4017503A (en) * | 1975-06-12 | 1977-04-12 | Merck & Co., Inc. | Antifungal 1-substituted benzimidazoles |
AR213309A1 (es) * | 1976-05-05 | 1979-01-15 | Rohm & Haas | Procedimiento para preparar 2-amino-isotioureidobencenos substituidos |
JPH082633A (ja) * | 1994-06-16 | 1996-01-09 | Asahi Sousetsu Kk | ネットコンベヤと、それを使用するネットコンベヤ装置 |
-
1984
- 1984-12-11 IT IT23993/84A patent/IT1177379B/it active
-
1985
- 1985-12-05 DE DE8686900104T patent/DE3584288D1/de not_active Expired - Fee Related
- 1985-12-05 AT AT86900104T patent/ATE68003T1/de not_active IP Right Cessation
- 1985-12-05 WO PCT/EP1985/000667 patent/WO1986003495A2/fr active IP Right Grant
- 1985-12-05 JP JP61500116A patent/JPS62501212A/ja active Pending
- 1985-12-05 EP EP86900104A patent/EP0217804B1/fr not_active Expired - Lifetime
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4059693A (en) * | 1976-06-11 | 1977-11-22 | University Patents, Inc. | Analgesic action of substance P |
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, Volume 92, 1980, Columbus Ohio, (US), page 706, Abstract 181680q & JP, A, 8002633 (Eisai co., Ltd.) 10 January 1980 * |
Also Published As
Publication number | Publication date |
---|---|
DE3584288D1 (de) | 1991-11-07 |
IT8423993A1 (it) | 1986-06-11 |
EP0217804B1 (fr) | 1991-10-02 |
EP0217804A1 (fr) | 1987-04-15 |
IT1177379B (it) | 1987-08-26 |
JPS62501212A (ja) | 1987-05-14 |
WO1986003495A2 (fr) | 1986-06-19 |
IT8423993A0 (it) | 1984-12-11 |
ATE68003T1 (de) | 1991-10-15 |
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