UY39388A - NEW COMPOUNDS THAT JOIN THE NR 1 H4 RECEIVER (FXR) AND ACT AS ANTAGONISTS TO FXR4 - Google Patents
NEW COMPOUNDS THAT JOIN THE NR 1 H4 RECEIVER (FXR) AND ACT AS ANTAGONISTS TO FXR4Info
- Publication number
- UY39388A UY39388A UY0001039388A UY39388A UY39388A UY 39388 A UY39388 A UY 39388A UY 0001039388 A UY0001039388 A UY 0001039388A UY 39388 A UY39388 A UY 39388A UY 39388 A UY39388 A UY 39388A
- Authority
- UY
- Uruguay
- Prior art keywords
- fxr4
- fxr
- antagonists
- act
- new compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente invención se refiere a nuevos compuestos que se unen al receptor NR1H (FXR) y actúan como antagonistas de FXR4 ; teniendo el compuesto la fórmula (ver representación gráfica de la fórmula)The present invention relates to new compounds that bind to the NR1H receptor (FXR) and act as antagonists of FXR4; the compound having the formula (see graphic representation of the formula)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161507153P | 2011-07-13 | 2011-07-13 | |
EP11005722A EP2545964A1 (en) | 2011-07-13 | 2011-07-13 | Novel FXR (NR1H4) binding and activity modulating compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
UY39388A true UY39388A (en) | 2021-09-30 |
Family
ID=62454900
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001039388A UY39388A (en) | 2011-07-13 | 2021-08-18 | NEW COMPOUNDS THAT JOIN THE NR 1 H4 RECEIVER (FXR) AND ACT AS ANTAGONISTS TO FXR4 |
Country Status (4)
Country | Link |
---|---|
JP (3) | JP2018123152A (en) |
HK (2) | HK1244682A1 (en) |
IL (3) | IL253437A0 (en) |
UY (1) | UY39388A (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6639078B1 (en) * | 1998-12-23 | 2003-10-28 | Smithkline Beecham Corporation | Assays for ligands for nuclear receptors |
CA2651373A1 (en) * | 2006-05-24 | 2007-12-06 | Eli Lilly And Company | Compounds and methods for modulating fxr |
EP1894924A1 (en) * | 2006-08-29 | 2008-03-05 | Phenex Pharmaceuticals AG | Heterocyclic FXR binding compounds |
EP2289883A1 (en) * | 2009-08-19 | 2011-03-02 | Phenex Pharmaceuticals AG | Novel FXR (NR1H4) binding and activity modulating compounds |
EP2545964A1 (en) * | 2011-07-13 | 2013-01-16 | Phenex Pharmaceuticals AG | Novel FXR (NR1H4) binding and activity modulating compounds |
-
2017
- 2017-07-12 IL IL253437A patent/IL253437A0/en active IP Right Grant
-
2018
- 2018-03-26 HK HK18104110.7A patent/HK1244682A1/en unknown
- 2018-04-04 JP JP2018072746A patent/JP2018123152A/en active Pending
- 2018-05-18 HK HK18106486.8A patent/HK1246716A1/en unknown
-
2019
- 2019-04-11 IL IL265973A patent/IL265973B/en active IP Right Grant
- 2019-08-26 JP JP2019153457A patent/JP6878526B2/en active Active
-
2020
- 2020-09-24 IL IL277570A patent/IL277570A/en unknown
-
2021
- 2021-03-05 JP JP2021035272A patent/JP2021091727A/en not_active Withdrawn
- 2021-08-18 UY UY0001039388A patent/UY39388A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2018123152A (en) | 2018-08-09 |
JP2021091727A (en) | 2021-06-17 |
JP6878526B2 (en) | 2021-05-26 |
IL265973B (en) | 2020-10-29 |
HK1246716A1 (en) | 2018-09-14 |
HK1244682A1 (en) | 2018-08-17 |
IL265973A (en) | 2019-06-30 |
IL277570A (en) | 2020-11-30 |
IL253437A0 (en) | 2017-09-28 |
JP2019214611A (en) | 2019-12-19 |
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