UY39097A - Sal de potasio del ácido 2-[(4s)-8-fluoro-2-[4-(3- metoxifenil)piperazin-1-il]-3-[2-metoxi-5- (trifluorometil)fenil]-4h-quinazolin-4-il]acético - Google Patents

Sal de potasio del ácido 2-[(4s)-8-fluoro-2-[4-(3- metoxifenil)piperazin-1-il]-3-[2-metoxi-5- (trifluorometil)fenil]-4h-quinazolin-4-il]acético

Info

Publication number
UY39097A
UY39097A UY0001039097A UY39097A UY39097A UY 39097 A UY39097 A UY 39097A UY 0001039097 A UY0001039097 A UY 0001039097A UY 39097 A UY39097 A UY 39097A UY 39097 A UY39097 A UY 39097A
Authority
UY
Uruguay
Prior art keywords
quinazolin
piperazin
fluoro
potassium salt
acid
Prior art date
Application number
UY0001039097A
Other languages
English (en)
Inventor
Helmut Buschmann
Thomas Goldner
Carles Ceron Bertran Jordi
Original Assignee
Aic246 Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aic246 Gmbh & Co Kg filed Critical Aic246 Gmbh & Co Kg
Publication of UY39097A publication Critical patent/UY39097A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a la sal de potasio del ácido 2-[(4S)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4H-quinazolin-4-il] acético y solvatos de la misma. La invención se refiere además a métodos de preparación de dicha sal de potasio del ácido 2-[(4S)-8-fluoro 2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4H-quinazolin-4-il] acético o solvatos de la misma, así como composiciones farmacéuticas que comprenden dicha sal.
UY0001039097A 2020-02-27 2021-02-26 Sal de potasio del ácido 2-[(4s)-8-fluoro-2-[4-(3- metoxifenil)piperazin-1-il]-3-[2-metoxi-5- (trifluorometil)fenil]-4h-quinazolin-4-il]acético UY39097A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20159742 2020-02-27

Publications (1)

Publication Number Publication Date
UY39097A true UY39097A (es) 2021-09-30

Family

ID=69742731

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001039097A UY39097A (es) 2020-02-27 2021-02-26 Sal de potasio del ácido 2-[(4s)-8-fluoro-2-[4-(3- metoxifenil)piperazin-1-il]-3-[2-metoxi-5- (trifluorometil)fenil]-4h-quinazolin-4-il]acético

Country Status (19)

Country Link
US (1) US20230150950A1 (es)
EP (1) EP4110471A1 (es)
JP (1) JP2023524349A (es)
KR (1) KR20220148860A (es)
CN (1) CN115427112A (es)
AR (1) AR121437A1 (es)
AU (1) AU2021227281A1 (es)
BR (1) BR112022016890A2 (es)
CA (1) CA3169075A1 (es)
CL (1) CL2022002294A1 (es)
CO (1) CO2022012006A2 (es)
CU (1) CU20220046A7 (es)
EC (1) ECSP22066666A (es)
IL (1) IL295644A (es)
MX (1) MX2022010442A (es)
PE (1) PE20230512A1 (es)
TW (1) TWI819279B (es)
UY (1) UY39097A (es)
WO (1) WO2021170882A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
DE102005027517A1 (de) 2005-06-15 2006-12-21 Bayer Healthcare Ag Verfahren zur Herstellung von Dihydrochinazolinen
DE102012101659A1 (de) 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Salze eines Dihydrochinazolinderivats

Also Published As

Publication number Publication date
BR112022016890A2 (pt) 2022-12-06
TW202140455A (zh) 2021-11-01
ECSP22066666A (es) 2022-12-30
US20230150950A1 (en) 2023-05-18
IL295644A (en) 2022-10-01
KR20220148860A (ko) 2022-11-07
MX2022010442A (es) 2022-10-18
CL2022002294A1 (es) 2023-02-03
AU2021227281A1 (en) 2022-10-13
JP2023524349A (ja) 2023-06-12
TWI819279B (zh) 2023-10-21
CA3169075A1 (en) 2021-09-02
WO2021170882A1 (en) 2021-09-02
CN115427112A (zh) 2022-12-02
AR121437A1 (es) 2022-06-08
CU20220046A7 (es) 2023-04-10
PE20230512A1 (es) 2023-03-24
EP4110471A1 (en) 2023-01-04
CO2022012006A2 (es) 2022-11-18

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